About the job
We are seeking a highly skilled Senior Director of Medicinal Chemistry to join our innovative team at Genesis Molecular AI. In this pivotal role, you will leverage our cutting-edge platform to spearhead medicinal chemistry initiatives that drive drug discovery from Hit Identification to candidate nomination. You will be a key collaborator and leader in multidisciplinary drug discovery projects, shaping the medicinal chemistry strategy for each project. As a recognized leader in medicinal chemistry, you will possess exceptional communication skills, facilitating collaboration with both internal teams and external partners.
Key Responsibilities
Develop and implement medicinal chemistry strategies utilizing the Genesis platform to effectively manage drug discovery programs from Hit ID through to candidate nomination.
Apply Structure-Based Drug Design (SBDD) principles, optimize physicochemical properties, and interpret in vitro and in vivo ADME/PK/Toxicology data to advance projects.
Employ data visualization software and metrics-driven analysis to formulate medicinal chemistry hypotheses and prioritize project strategies.
Engage and collaborate with industry partners on various drug discovery projects.
Work closely with other drug discovery disciplines, including biology, DMPK, software engineering, and computational chemistry, to foster hypothesis-driven decisions and enhance platform capabilities.
Maintain regular communication and engagement with project teams and management to ensure alignment and progress.
Mentor and guide internal chemists and other scientific professionals on medicinal chemistry best practices.

