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Senior Director of Medicinal Chemistry

On-site Full-time $300K/yr - $300K/yr

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Experience Level

Senior Level Manager

Qualifications

QualificationsPhD in synthetic organic chemistry or medicinal chemistry with a minimum of 12 years of relevant experience in industrial drug discovery, ORMS in synthetic organic chemistry with at least 18 years of experience in industrial drug discovery. Demonstrated expertise in medicinal chemistry, particularly in SBDD and optimization of drug-like properties. Proficient in metrics-based analysis and data visualization to enhance decision-making and efficiency. Exceptional communication skills for both team collaboration and professional presentations. Proven experience in leading drug discovery programs. Strong foundation in synthetic chemistry and problem-solving abilities. Eagerness to adopt new technologies, coupled with strong interpersonal skills and a commitment to continuous learning.

About the job

We are seeking a highly skilled Senior Director of Medicinal Chemistry to join our innovative team at Genesis Molecular AI. In this pivotal role, you will leverage our cutting-edge platform to spearhead medicinal chemistry initiatives that drive drug discovery from Hit Identification to candidate nomination. You will be a key collaborator and leader in multidisciplinary drug discovery projects, shaping the medicinal chemistry strategy for each project. As a recognized leader in medicinal chemistry, you will possess exceptional communication skills, facilitating collaboration with both internal teams and external partners.

Key Responsibilities

  • Develop and implement medicinal chemistry strategies utilizing the Genesis platform to effectively manage drug discovery programs from Hit ID through to candidate nomination.

  • Apply Structure-Based Drug Design (SBDD) principles, optimize physicochemical properties, and interpret in vitro and in vivo ADME/PK/Toxicology data to advance projects.

  • Employ data visualization software and metrics-driven analysis to formulate medicinal chemistry hypotheses and prioritize project strategies.

  • Engage and collaborate with industry partners on various drug discovery projects.

  • Work closely with other drug discovery disciplines, including biology, DMPK, software engineering, and computational chemistry, to foster hypothesis-driven decisions and enhance platform capabilities.

  • Maintain regular communication and engagement with project teams and management to ensure alignment and progress.

  • Mentor and guide internal chemists and other scientific professionals on medicinal chemistry best practices.

About Genesis Molecular AI

Genesis Molecular AI is at the forefront of drug discovery, utilizing advanced AI-driven technologies to revolutionize the pharmaceutical industry. Our mission is to accelerate the development of novel therapeutics, improving patient outcomes and transforming lives through innovative science.

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