About the job
Vivodyne: Innovating Human Data for Clinical Trials.
At Vivodyne, we revolutionize the discovery, design, and development of human therapeutics. By utilizing large, lab-grown human organ tissues at unprecedented scale, we propel technological advancements at the intersection of cutting-edge biology, robotics, and artificial intelligence. Our innovative approach allows us to identify and validate new therapeutic targets while de-risking therapeutic assets through the generation of clinically translatable multi-omic data. This capability enables the production of more human data than all clinical trials in the U. S. combined. We are supported by some of the most prestigious venture funds and have established partnerships with many of the world's leading pharmaceutical companies to enhance drug discovery and development while significantly reducing reliance on animal testing.
Role Overview
As the Principal Mechanical Engineer at Vivodyne, you will collaborate within a dynamic, multi-disciplinary team, pioneering advancements in automated, large-scale "organ-on-a-chip" robotics and associated manufacturing systems. Your primary focus will be on the development and optimization of hardware and software that coordinates robotic arms, embedded controllers, and microfluidic systems to facilitate high-throughput and high-precision biological workflows.
This position demands a strong expertise in hardware, although knowledge in software is beneficial. You will engage with high-level motion control, machine vision, and robotics programming, working primarily with Python, while occasionally interacting with C# and C++ codebases to ensure seamless system integration and optimal performance.
As an expert in mechanical design, you have a deep understanding of concepts like kinematic docking, material selection (440 vs 316), finite element analysis (FEA), and error budgets. You are well-acquainted with suppliers such as McMaster-Carr, Misumi, and Grainger.
Collaboration is essential in this role; you will work closely with mechanical engineers, biologists, immunologists, AI scientists, and process engineers to design and enhance automation workflows that lead to groundbreaking discoveries. We seek a problem-solver who thrives in a fast-paced, innovative environment that prioritizes continuous learning and technical excellence.
This is a full-time, onsite position located in San Francisco, where you will be integral to designing, building, and testing transformative technologies.

