About the job
Isomorphic Labs is hiring a Head of Translational Sciences, Drug Design for its Cambridge, MA site. This senior leader will guide the translational strategy across the drug discovery portfolio, working closely with teams at the intersection of biology, artificial intelligence, and medicine. The position plays a central role in shaping how new therapies are advanced and how disease mechanisms are understood within the organization.
Role overview
This leadership role focuses on driving translational approaches for drug design. The Head of Translational Sciences will collaborate with colleagues to advance projects from early discovery through clinical evaluation. The team’s work includes strengthening biological insights into disease, supporting the selection of drug targets, and developing biomarkers to track pharmacodynamic effects and target engagement in clinical studies.
Translational Sciences at Isomorphic Labs
The Translational Sciences group in Boston is essential to the company’s mission. This team informs critical decisions across the portfolio, guiding projects through various stages of research and development. Close collaboration with other teams ensures that scientific progress benefits from both biological expertise and AI-driven insights.
Company background
Founded in 2021, Isomorphic Labs (IsoLabs) builds on the breakthroughs of the AlphaFold system. The company brings together drug discovery experts and machine learning specialists to develop predictive and generative AI models that accelerate scientific progress. The team uses AI to model complex biological systems, design new therapeutic molecules, and pursue treatments for challenging diseases. Ongoing innovation in model architecture supports work across diverse therapeutic areas and modalities.
Culture
Isomorphic Labs values interdisciplinary collaboration and a supportive environment. Every team member contributes to the shared goal of addressing serious diseases through AI-driven science and digital biology.

