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Director of Upstream MSAT & Process Development

Scholar RockCambridge, MA
On-site Full-time

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Experience Level

Senior Level Manager

Qualifications

Qualifications:Advanced degree in Life Sciences, Engineering, or related field. Significant experience in upstream process development and MSAT in a biopharmaceutical setting. Proven leadership skills with a track record of managing teams and external partners. Strong knowledge of GMP regulations and compliance standards. Excellent communication and project management abilities.

About the job

Scholar Rock is a pioneering biopharmaceutical firm dedicated to discovering, developing, and delivering transformative therapies for individuals afflicted by severe diseases with significant unmet medical needs. Renowned for its leadership in the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins, the company has established a strong clinical focus on advancing groundbreaking treatments that leverage protein growth factors. Over the last decade, Scholar Rock has developed a robust pipeline aiming to redefine the standard of care for neuromuscular diseases, cardiometabolic disorders, cancer, and other conditions where growth factor-targeted therapies can create profound impacts.
 
As the sole organization to demonstrate clinical proof of concept for a muscle-targeted therapy in spinal muscular atrophy (SMA), Scholar Rock is committed to pioneering innovative therapeutic strategies. This commitment is bolstered by the extensive application of its proprietary platform, which has successfully generated novel monoclonal antibodies designed to modulate protein growth factors with remarkable precision. By harnessing advanced scientific methodologies in historically underserved disease areas, Scholar Rock is dedicated to expanding treatment possibilities for patients. Discover more about our unique approach at ScholarRock.com and connect with us on @ScholarRock and LinkedIn.

Position Overview:

We are on the lookout for a strategic and experienced Director of Upstream MSAT and Process Development to lead our biologics upstream MSAT and process development initiatives across early, late, and commercial program stages. This pivotal role will oversee externally partnered GMP production of Scholar Rock’s clinical and commercial assets, leveraging extensive manufacturing science and technology expertise. The successful candidate will spearhead the design, scale-up, and technology transfer of drug substance processes, both internally and through our global network of CDMOs. The ideal candidate will possess profound upstream technical knowledge, exceptional organizational leadership, and a proven track record in managing external collaborations alongside in-house teams. This role is essential for establishing resilient and scalable processes that underpin our clinical and commercial success.

About Scholar Rock

Scholar Rock is at the forefront of biopharmaceutical innovation, dedicated to creating life-altering therapies for patients with unmet medical needs. The company specializes in leveraging the science of growth factors to develop treatments that may significantly improve patient outcomes in critical therapeutic areas.

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