Staff / Principal Mechanical Engineer

Your Contribution at Lila Sciences Lila Sciences is on the lookout for a motivated Automation Engineer I to enhance our Integrated Automation Engineering Team. This role offers an exciting opportunity to engage in the creation and refinement of our state-of-the-art automated workcells. As an Automation Engineer I, you will be pivotal in diagnosing and addressing operational challenges while fueling the innovation that propels our objective of achieving scientific superintelligence. Your responsibilities will encompass pioneering automation solutions in life science laboratories and extending into material and physical sciences, thereby supporting a myriad of applications, including drug discovery, bioengineering, and advanced material characterization. This position promises to equip you with invaluable hands-on experience in an energetic and collaborative environment, aiding in the cultivation of a broad skill set that will be beneficial for your future endeavors in science and technology. Your Responsibilities Identify, categorize, and resolve issues associated with automated workcells. Efficiently troubleshoot software and electro-mechanical systems, swiftly learning new technologies and documenting processes for team knowledge sharing. Proactively pinpoint potential failure points and spearhead initiatives to mitigate them. Develop automated processes or tools to facilitate the attainment of Lila's objectives. Collaborate on significant projects to gain practical experience and create a tangible impact, including initiatives focused on proactive issue identification, preventive maintenance, and AI integration into troubleshooting operations.

We are seeking a talented Automation Software Engineer to join our dynamic team at ttp1. In this role, you will be responsible for developing and implementing automation solutions that enhance our software products and services. Your expertise will play a critical role in optimizing our processes and ensuring the highest standards of software quality. If you are passionate about automation, have a strong background in software engineering, and thrive in a collaborative environment, we want to hear from you!

Your Impact at Lila Sciences Lila Sciences is in search of an experienced and proactive Senior Automated Systems Engineer to spearhead the design, development, and implementation of innovative automation solutions across various laboratory workflows. This pivotal role, reporting to the Automated Systems Engineering Lead, focuses on creating scalable, high-throughput automated workcells that effectively translate scientific objectives into dependable, real-world systems. As an integral member of our team, you will collaborate closely with scientists, hardware, controls, and software teams to define project scope, ensure interface alignment, and guide projects from conception through to deployment. You will work in partnership with scientific stakeholders to shape the technical direction of experimental automation in a dynamic research environment. Your Contributions Engage in hands-on development, testing, and implementation of automated workflows within the laboratory. Engineer scalable automated solutions tailored for synthesis and characterization workflows, catering to a diverse array of material systems including porous materials, catalysts, coatings, and advanced composites. Establish and document standardized laboratory workflows, operating procedures, and system architectures to promote reproducibility and scalability. Lead and participate in equipment and system-level Failure Mode and Effects Analyses (FMEAs) to enhance robustness and operational safety. Assist in troubleshooting and optimizing automated systems to maximize throughput, reliability, and adaptability across various workflows. Design failure detection methodologies and maintain laboratory automation systems to ensure robust operations. Project Innovation Convert scientific goals into well-defined technical requirements and automation architectures. Serve as a liaison among science, hardware, controls, and software to ensure clarity in interfaces and cohesiveness in solutions. Investigate and incorporate emerging technologies, such as machine vision and advanced sensors, to boost automation capabilities. Ensure that automation solutions adhere to safety, quality, and regulatory standards.

Teamwork Makes the Stream Work. Join Roku and Transform TV Viewing Worldwide!At Roku, we are revolutionizing how the world watches television. As the leading TV streaming platform in the U.S., Canada, and Mexico, our ambition is to power every television globally. We pioneered streaming to the TV, and our mission is to connect the entire TV ecosystem, empowering consumers to access their favorite content, enabling publishers to build and monetize large audiences, and providing advertisers with unique engagement opportunities.From your very first day, you will contribute significantly to our mission. We are a dynamic public company where every team member plays a vital role. This is your opportunity to engage millions of TV streamers worldwide while gaining invaluable experience across various disciplines. About the RoleWe are looking for a talented Software Engineer with expertise in Python and automation, who has experience developing automated tools and tests for resource-constrained hardware platforms. Your work will involve creating and maintaining tools and tests that enhance our products and guarantee the highest quality in software releases deployed to devices in the field. In this role, you will develop solutions for testing, monitoring, and analyzing metrics across millions of players and TV products.As a versatile Software Engineer at Roku, you will be responsible for building fully automated test suites and performance monitoring tools. You will create automation that validates both the Roku OS system software and top-tier streaming applications across Roku TVs and Players, alongside the necessary infrastructure. This includes extending existing tests and developing new ones to assess memory usage, playback performance, compliance with specifications, and more. You will also maintain a multi-platform device farm for use by test and firmware engineers.This role requires a proactive and motivated individual with excellent communication, organizational, and technical skills, as you will collaborate cross-functionally with various engineering teams. Key ResponsibilitiesDevelop and maintain an automation framework for testing high-profile streaming applications.Collaborate with engineering teams to ensure seamless integration of automated testing solutions.Extend and create tests to evaluate memory consumption, playback efficiency, and adherence to specifications.Manage a multi-platform device testing environment.

We are seeking a passionate and detail-oriented Scientist I to join our innovative team at Integrated Resources Inc. This entry-level position offers a fantastic opportunity to contribute to groundbreaking research and development projects. You will work closely with experienced scientists to support various laboratory activities, including experimental design, data collection, and analysis.

Join Engine as a Senior Associate in Community OperationsAt Engine, we empower visionary founders who are tackling the world's most critical challenges in areas such as climate change, health, and advanced technologies. Our commitment includes providing robust support through founder programs, access to shared infrastructure and labs, and the opportunity to connect with a diverse national network of corporate partners, investors, and industry experts.

We are seeking a motivated and detail-oriented Scientist I to join our dynamic team in Cambridge. The ideal candidate will have a strong background in scientific research, with a passion for innovation and problem-solving. This entry-level role offers an exciting opportunity to contribute to groundbreaking projects and advance your career in a collaborative environment.

Role Overview The Building Engineer I at LPC supports the daily operation and maintenance of building systems in Cambridge, MA. Working under the guidance of senior engineers, this role focuses on HVAC, plumbing, and electrical systems. The position involves routine maintenance, responding to tenant requests, and helping ensure safe, efficient building operations. Main Responsibilities Perform regular maintenance, repairs, and inspections of building systems. Respond to service requests, including temperature adjustments, plumbing issues, and lighting repairs. Diagnose minor equipment problems and escalate complex issues to senior staff as needed. Replace light fixtures, filters, and other key components. Keep accurate records of inspections and system performance. Communicate clearly with tenants, contractors, and property managers to resolve concerns and coordinate activities. Work closely with senior engineers and technicians to support smooth building operations. Assist with preventive maintenance tasks and oversee contractor work when required. Conduct property inspections to identify and document deficiencies. Record equipment readings to confirm compliance with operational standards. Follow safety protocols, wear required PPE, and comply with OSHA, NEC, NFC, and NFPA regulations. Report hazards and participate in safety inspections. Offer guidance to junior technicians when needed. Communicate professionally in both verbal and written formats with teammates, leadership, vendors, tenants, and client employees. Collaborate with senior engineers to build technical skills and participate in professional development programs. Complete additional duties as assigned.

Your Impact at Lila In this pivotal role, you will spearhead the innovation and validation of advanced pooled assays utilizing mammalian cells. Your work will encompass everything from proof of concept to automated screening processes, enabling the generation of intricate, high-dimensional datasets. This position involves collaboration across cell biology, protein design, and nucleic acid teams to facilitate biologic development programs, focusing on the rapid assessment of binding, stability, function, and immunogenicity of diverse biologics. What You'll Be Building Create next-generation mammalian display-based assays for binding, stability, function, and immunogenicity. Implement cutting-edge multiomic, single-cell, and in situ sequencing workflows to design innovative, highly multiplexed assays. Collaborate with protein design, nucleic acid, and automation teams to leverage these workflows in biologics development. Closed-Loop Experimentation and Execution: Work closely with engineering and automation teams to architect automated, high-throughput experimentation platforms that yield data-rich workflows. Join forces with the AI team to conduct iterative experiments in real time, facilitating rapid optimization and discovery cycles. Collaborate, Lead & Communicate: Engage with cell biologists, synthetic biologists, automation engineers, protein design scientists, and data scientists to document systems, share insights, and refine best practices in autonomous science. Mentor junior scientists, align project milestones with internal and external collaborators, contribute to intellectual property and publications, and present findings across the organization. What You’ll Need to Succeed Ph.D. in Chemical/Biomedical Engineering, Biochemistry, Pharmaceutical Sciences, Immunology, or a related discipline (or M.S./B.S. with 5–8+ years of relevant industry experience). Proficiency in the development and/or application of mammalian display or similar pooled mammalian systems (perturb-seq, MPRA, etc.). Experience in designing, executing, and analyzing single-cell, in situ, or multiomic sequencing experiments. Expertise in creating complex libraries of defined sequences in mammalian cells. Experience in designing, executing, and analyzing flow cytometry and sorting experiments. Familiarity with next-generation sequencing (NGS) based experimental design and analysis.

The Engine supports Tough Tech entrepreneurs who are developing solutions for major global challenges. As a nonprofit, the organization connects founders with infrastructure, funding, and operational support to help turn breakthrough science and technology into real-world impact. Role overview The Chief Growth Officer (CGO) will lead The Engine through its next phase of growth. This executive shapes partnership strategies, drives revenue initiatives, and works to strengthen the organization’s market position. The CGO also serves as a strategic advisor to the CEO and leadership team, providing input on key organizational decisions. Who should apply Experienced leaders with a background in Tough Tech, either as entrepreneurs or commercial executives Individuals with a track record of scaling organizations and launching first-of-a-kind (FOAK) projects Candidates who have advocated for Tough Tech founders and engaged with the broader ecosystem Location This position is based in Cambridge.

About the Role Lila Sciences, Inc. is looking for a Controls Engineer in Cambridge, MA. This position focuses on designing and implementing control systems that support the performance and reliability of the company's products. What You Will Do Design control systems for new and existing products Implement and test system functionality to meet performance goals Contribute technical expertise to projects that require reliable, precise control Location This role is based in Cambridge, MA, USA.

Are you ready to lead the electronics vision for advanced laboratory automation as the Engineering Manager within the Electronics team at SPT Labtech? In this pivotal role, you will hold technical authority over electronics, motion control, and low-level system integration, while inspiring and developing a high-performing engineering team. Your hands-on approach to design, architecture, and problem-solving will enable you to collaborate closely with software and mechanical teams, ensuring the delivery of precise, reliable, and high-performance control of complex electromechanical systems.This position is ideal for a seasoned engineer with extensive expertise in electronics and embedded systems, robust motion-control capabilities, and a knack for overcoming intricate technical challenges through effective collaboration across disciplines.About Us:Located in the heart of Cambridge, SPT Labtech revolutionizes the way scientists conduct their research. For many years, our dedicated scientists, engineers, and business innovators have provided cutting-edge, innovative solutions for liquid handling, sample preparation, and sample management, accelerating research and significantly impacting human health. We pride ourselves on fostering collaborative relationships with our customers, delivering exceptional, tailored experiences that address real-world laboratory challenges.Are you eager to be part of a team making a tangible impact?Your Key Responsibilities Will Include:1. Team Leadership & DevelopmentBuild and nurture the electronics engineering team, ensuring adherence to high technical standards and professional development. Guarantee that solutions comply with regulations and meet Quality, Delivery, and Cost objectives.Collaborate with program and portfolio leads, along with the R&D Director, to prioritize tasks and resource planning, ensuring the electronics team is aligned and able to deliver effectively.Enhance engineering processes, design reviews, documentation standards, and verification methodologies.Encourage a culture of ownership, teamwork, and practical problem-solving.Oversee small to medium-scale projects as necessary, while providing technical guidance and best practices to team members.2. Technical LeadershipServe as the primary authority for electronics design and motion control across the entire product line.Establish and maintain the architecture for electronics and control systems, ensuring seamless integration with software, firmware, and mechanical teams.Adopt a system-level perspective in design decisions, ensuring that choices in electronics and motion control support the overall product architecture, performance, and reliability.Lead the development of motion-control strategies, offering direction on actuation and control...

Join Luminance, a trailblazer in Legal-Grade™ AI for enterprises, recognized by top-tier venture capitalists and featured in Forbes AI 50 and Inc. 5000 lists for innovation and growth. Our mission is to transform the legal industry worldwide.We are seeking a proactive DevSecOps Engineer to enhance our security engineering capabilities and integrate security practices within our platform and development processes. In this role, you will collaborate with teams across Platform (SRE), IT Infrastructure, and Security to establish secure controls, automate workflows, and elevate risk management practices. If you thrive on resolving practical security engineering challenges and creating automation solutions that prioritize secure development, we want to hear from you.The ideal candidate will concentrate on automation, security control implementation, cloud security enhancement, and achieving significant improvements in our security framework.

Teamwork makes the stream work. Join Roku - Pioneering TV Streaming TechnologyRoku is the leading TV streaming platform in the U.S., Canada, and Mexico, aspiring to power every television globally. We revolutionized how audiences consume content and strive to connect consumers with the media they adore. Our platform empowers content creators to grow and monetize their audience while offering advertisers unique ways to connect with consumers.From day one at Roku, your contributions will be significant and appreciated. As a rapidly expanding public company, we foster an environment where every team member is actively engaged. This is your chance to make a difference for millions of TV streamers worldwide while gaining invaluable experience across various domains. About the TeamThe automation and tools teams at Roku are the driving force behind enhancing our testing and developer experience. By leveraging AI and analytics, these teams create frameworks, pipelines, and developer utilities that elevate validation coverage, accelerate release cycles, and enhance engineering productivity across embedded, mobile, and cloud services. Role OverviewWe invite you to join our automation and tools team as a Software Engineer Intern at Roku, where your passion for technology and creativity will be instrumental in our growth. This is a paid 12-week internship commencing in Summer 2026.As a Software Engineer Intern, you will undertake a project aimed at enhancing automation or developer tooling—possible tasks might include extending a Python test framework, developing a lightweight web or AI tool, or integrating automation into CI/CD processes. Your ResponsibilitiesLead an automation/tools project; examples include enhancing a Python test framework, creating a service for test orchestration, or integrating test steps into CI/CD pipelines.Write clean, reusable code (predominantly in Python and TypeScript/JavaScript for web tools); engage in code reviews and document your work for maintainability.Collaborate with engineers across different locations to implement enhancements and gather feedback. Preferred QualificationsProficient in Python programming with a solid understanding of REST APIs and a web framework (Flask, FastAPI, Django, Node.js, or Express).Interest in CI/CD tools (Jenkins, GitLab CI) and familiarity with automation practices.

Your Contribution at Lila Sciences Lila Sciences is seeking a passionate Software Engineer to spearhead the development of cutting-edge Lab Instrument Integration Software, a crucial element of our AI-powered laboratory ecosystem. We want innovative thinkers who thrive at the intersection of software, science, and hardware, delivering impactful solutions that propel scientific advancements. Key Responsibilities Lab Instrument Software Development: Design and implement reliable software that facilitates seamless communication between robotic systems and automation hardware (e.g., robotic arms, liquid handlers, sensors) and control software, guaranteeing effective hardware integration. System Integration: Integrate lab instruments into our next-gen AI-driven lab automation framework, managing intricate connections between cloud and edge infrastructures, along with device execution. Testing and Debugging: Conduct comprehensive testing, debugging, and troubleshooting of drivers to pinpoint, isolate, and resolve performance issues, bugs, and compatibility hurdles. Technical Documentation: Develop, revise, and maintain thorough documentation for driver interfaces, APIs, and integration procedures, ensuring clarity for internal teams and end-users. Collaboration and Support: Partner with cross-functional teams, including hardware engineers, software developers, product managers, and end-users, to provide technical assistance and resolve integration challenges efficiently. AI-Driven Development: Leverage advanced coding models and development tools to enhance the speed and quality of software delivery. Qualifications for Success Proficiency in Python, C#/.NET, or other programming languages/frameworks is essential. Proven experience in debugging and problem-solving, particularly in hardware-software integration contexts. Strong analytical skills and a methodical approach to troubleshooting complex technical challenges. Excellent verbal and written communication skills to facilitate effective collaboration within multidisciplinary teams. Bonus Qualifications A keen interest or background in science. Experience in developing software for laboratory instruments.

Your Role at Lila SciencesJoin our innovative Physical Sciences division, where you will spearhead the development of intelligent agent-driven systems designed to enhance AI-accelerated and AI-orchestrated process engineering across diverse industrial applications. In this pivotal role, your mission will be to create methodologies empowering AI agents to reason, design, simulate, optimize, and operate complex physical and chemical processes using both traditional and machine learning-driven process engineering tools. You will focus on building agentic infrastructures that facilitate AI systems in planning and executing multi-step process engineering workflows, which include process synthesis, flowsheet generation, steady-state and dynamic simulation, control strategy design, and techno-economic evaluation. Your contributions will significantly influence how Lila's scientific superintelligence addresses real-world challenges through closed-loop autonomous process engineering.Your ContributionsDesign and implement agentic frameworks supporting comprehensive process engineering workflows, encompassing process setup, simulation, optimization, and analysis.Create AI agents capable of autonomously planning, executing, and refining process engineering tasks utilizing existing tools such as steady-state and dynamic simulators, optimizers, and data systems.Investigate agentic strategies for advanced objectives, including process intensification, control co-design, real-time optimization, and closed-loop learning informed by operational data.Enhance the robustness, interpretability, and reproducibility of agent-driven process engineering workflows; develop internal tools for debugging, observability, validation, and auditability.Collaborate with interdisciplinary teams to apply agentic process engineering across a wide range of industrial applications.

Join Cambridge Mobile Telematics (CMT), the leading telematics service provider dedicated to enhancing road safety and driver performance. Our AI-powered platform, DriveWell Fusion®, aggregates data from millions of IoT devices, including smartphones and connected vehicles, to deliver actionable insights for auto insurers, automakers, and mobility companies. Headquartered in Cambridge, MA, with a global presence in cities like Budapest, Chennai, and Tokyo, we protect millions of drivers every day.We are on the lookout for a talented Principal Software Engineer to spearhead ambitious projects while mentoring our engineering teams in developing robust and scalable full-stack solutions. This pivotal role involves setting the technical direction for our platform and contributing to its ongoing success.If you are a collaborative, innovative, and customer-focused engineer eager to make a real impact on road safety, we invite you to apply!

Your Role at Lila Sciences Lila Sciences is on the lookout for an experienced Principal Software Engineer specializing in Instrument Simulations. In this pivotal position, you will spearhead the architecture and development of our cutting-edge laboratory automation platform. Your expertise will be crucial in designing the simulation framework and integration layer that links AI-driven experimental design with physical robotic systems, enabling groundbreaking scientific discoveries at an unparalleled scale. Key Responsibilities Design and implement high-fidelity simulation environments that accurately model intricate laboratory instrumentation, fluidics, and robotic processes. Establish and maintain robust integration frameworks between diverse hardware systems, ensuring the safe and reliable execution of fully automated experiments. Lead the development of APIs and interfaces to facilitate seamless interaction between scientists and AI agents with complex automation infrastructures. Champion best practices in hardware-software integration, system monitoring, and continuous integration/deployment (CI/CD) within laboratory automation contexts. Provide mentorship to engineers, likely overseeing a small, agile team.

COMPANY DESCRIPTION Flagship Pioneering is a groundbreaking bioplatform innovation organization dedicated to inventing and building transformative companies that make a positive impact on the world. We unite exceptional scientific talent with entrepreneurial visionaries and mobilize substantial capital to enable bold advancements in human health, sustainability, and beyond. Our innovative efforts span critical areas such as disease detection and treatment, nature-positive agriculture, and pioneering applications of AI that catalyze the development of new technologies. What distinguishes Flagship is our unique ability to propel science and technology forward by integrating innovation, company creation, and capital investment within a cohesive framework that is largely unprecedented. Our scientific founders, entrepreneurial leaders, and professional capital managers share a commitment to an institutionalized process that empowers us to innovate and transform for the betterment of humanity and the planet. Many of our founded companies have tackled some of the most pressing challenges facing humanity: from vaccinating billions against COVID-19 to curing complex diseases, enhancing human health, preempting illness, and bolstering global food security through improved agricultural resilience and sustainability. Flagship has earned recognition on FORTUNE’s “Change the World” list, celebrating companies that have made a significant social and environmental impact through their core business strategies, and has been named twice to Fast Company’s annual list of the World’s Most Innovative Companies. THE ROLE We are on the lookout for a Senior Scientist I or II to spearhead microbial strain engineering initiatives that will support a pioneering biological platform within one of our stealth mode startups. This position will concentrate on the design, construction, and optimization of engineered microbial strains aimed at enabling scalable production systems. The ideal candidate will manage strain development cycles from genetic design to experimental validation, collaborating closely with our discovery and bioprocess development teams to translate initial biological insights into robust strains suitable for fermentation environments. This role will also provide technical leadership within our technical operations function and aid in establishing best practices for microbial engineering in a dynamic and collaborative R&D setting.