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Staff Machine Learning Engineer, Frontier AI

Ambience HealthcareSan Francisco
Hybrid Full-time $250K/yr - $250K/yr

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Experience Level

Mid to Senior

Qualifications

Lead foundational model research. Identify failure modes, develop hypotheses, and drive architectural decisions on complex clinical AI challenges — including medical coding, adaptive scribing, and chart comprehension. Create compounding learning loops. Develop systems that transform real-world signals — clinician edits, feedback, and more — into continuous improvement for our models.

About the job

About Us:

At Ambience Healthcare, we aspire to redefine healthcare technology. We are creating an AI intelligence platform that brings humanity back to healthcare while delivering significant ROI for health systems nationwide.

Our cutting-edge technology enables healthcare providers to concentrate on exceptional patient care by alleviating the administrative tasks that detract from their critical responsibilities. Ambience provides real-time, coding-aware documentation and clinical workflow support across various healthcare settings, including ambulatory, emergency, and inpatient environments, partnering with top health systems across North America.

We are relentless in our pursuit of excellence, exhibiting extreme ownership as we develop optimal solutions for our health system partners. We value transparency, positivity, and profound insight — holding each other to high standards because the challenges we tackle are of utmost importance.

Ambience has been recognized as the leading company for improving clinician experience in the KLAS Research Emerging Solutions Top 20 Report, named one of the Next Big Things in Tech by Fast Company, and selected as one of the best AI companies in healthcare by Inc. Additionally, we were honored as a LinkedIn Top Startup in 2024 and 2025. Our esteemed investors include Oak HC/FT, Andreessen Horowitz (a16z), OpenAI Startup Fund, and Kleiner Perkins — and we’re just getting started.

The Role:

As a Staff Machine Learning Engineer on the Frontier AI team at Ambience, you will tackle the most challenging model quality issues across our clinical AI products, including foundational coding models, adaptive scribing, voice agents, long-context chart understanding, and clinical reasoning. This role focuses on research direction, designing learning loops, and driving comprehensive improvements in model quality over time.

Ambience delivers advanced clinical AI solutions in real-world healthcare environments. The models that fuel our products operate under unique constraints, including proprietary ontologies, complex electronic health record (EHR) data, stringent compliance requirements, and clinician workflows where both latency and accuracy are critical. You will leverage your deep research instincts and engineering rigor to push the boundaries of what is possible.

Our engineering roles are hybrid, requiring in-office attendance at our San Francisco location three days a week.

About Ambience Healthcare

Ambience Healthcare is pioneering the future of healthcare technology with AI solutions that enhance clinician experience and streamline administrative tasks. Recognized as a leader in the healthcare AI space, we partner with top health systems to deliver innovative solutions that improve patient care.

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