Senior Software Engineer - Platform at Trunkio | San Francisco

Role overview Axiom Bio is looking for a Platform Engineer to join the team at the San Francisco Global HQ. The focus is on building and supporting scalable platforms that enable bioinformatics research. What you will do Collaborate with colleagues from a range of disciplines to design, implement, and maintain platforms for scientific teams Create systems that streamline research workflows and improve efficiency Support projects aimed at advancing bioinformatics capabilities Location This role is based on site at Axiom Bio's San Francisco Global HQ.

About Axiom: Axiom is the go-to destination for legal teams seeking the ideal talent for a diverse range of tasks, from standard in-house responsibilities to intricate outside counsel assignments. Legal departments often face the dilemma of high law firm fees, unnecessary full-time hires, or low-cost agencies that fail to meet quality expectations. Simultaneously, top legal professionals are eager to tackle challenging matters while maintaining control over their work conditions. Axiom bridges this gap by connecting mid-market and Fortune 500 companies with an extensive pool of experienced, specialized legal talent, adhering to the motto: 'work smarter, adapt faster, go further.' About the Team: At Axiom, we strive to infuse fresh energy and innovative thinking into a field bound by tradition. Our passion for the company we are building is palpable. We are dedicated to our mission and our people, celebrating successes, learning from setbacks, and finding opportunities in challenges. Our culture is built on inspiring collaboration, genuine relationships, and a commitment to listening and understanding our colleagues and clients. Our People: Innovative thinkers who challenge the status quo. Demonstrate an exceptional work ethic and a commitment to quality. Continuously seek personal growth and development. Embrace a positive outlook and assume the best intentions. Foster strong relationships and collaboration across diverse perspectives. Value learning from differing viewpoints. Leave a meaningful, lasting impact on those around them. About the Role: We are on the lookout for sales professionals to drive our growth across various sectors, including Technology, Financial Services, Consumer Services, Life Sciences, and Industrials/Energy Tech. We seek energetic evangelists—salespeople who can envision a prosperous future for clients, guide them toward that vision, and build enduring partnerships that surpass expectations. This role is tailored for a consultative seller who excels in engaging with executive-level decision-makers to develop solutions for their most pressing challenges. You will enjoy a high level of accountability and ownership over your work.

Join the Innovative Team at Topos BioAt Topos Bio, we are at the forefront of drug discovery, focusing on the challenging area of intrinsically disordered proteins—molecular targets that traditional methods have struggled to address, particularly in neurodegeneration, oncology, and cardiometabolic diseases.We are looking for a passionate and skilled Computational Chemist to join our dynamic team. This role involves the generation of novel molecules across diverse targets and requires close collaboration with AI researchers and experimental scientists to push the boundaries of drug discovery.Your ResponsibilitiesCreate and optimize scalable workflows for the generation and screening of thousands of potential drug candidates.Design and execute molecular dynamics simulations, employing advanced sampling methods to analyze protein-ligand interactions and conformational changes.Develop and refine data pipelines for managing large-scale molecular simulations and structure-based predictions.Construct and enhance cheminformatics pipelines for compound filtering, property prediction, similarity searching, and chemical space exploration.Collaborate with AI specialists to integrate simulation data into model training and inference frameworks.Ensure computational protocols are scientifically sound while delivering practical outcomes.Effectively communicate complex technical concepts to cross-functional teams, aiding in the understanding of capabilities and limitations.Remain informed on the latest advancements in computational chemistry, generative models, and molecular simulations.Lead scientific presentations to pharmaceutical partners, articulating the computational strategies employed by our team to both technical and non-technical audiences.QualificationsPhD in Computational Biophysics, Computational Chemistry, or a related discipline.Demonstrable experience in molecular modeling, simulation, and generative drug design.Proficient in computational biophysics software (e.g., AMBER, GROMACS, OpenMM, PLUMED, Schrödinger, OpenEye).Strong foundation in cheminformatics: molecular fingerprints, QSAR/QSPR, property prediction, scaffold analysis, and cheminformatics libraries (e.g., RDKit, OpenBabel).Expertise in at least one programming language, preferably Python.Experience with HPC clusters or cloud computing environments, containerization, and workflow management.

About HyperspellHyperspell is revolutionizing the Memory & Context Layer for AI Agents.AI agents are brilliant yet lack context.While AI agents excel in standardized testing, they struggle with real-world applications. Today's cutting-edge agents lack the contextual understanding that humans naturally acquire through diverse interactions. This context evolves with their tasks.Hyperspell empowers AI agents with contextual awareness by integrating with users' workspace data, creating a tailored memory and context layer.Our ValuesWe are committed to shaping the future through bold innovations. Our goal is to establish ourselves as the indispensable context layer for organizations, enabling all their AI agents to connect seamlessly. We embark on this journey not because it is easy, but because it is significant.We prioritize care — for our customers, their success, the future of AI, and most importantly, for one another. As we build the frontier of AI, we strive to be one of the most technologically advanced yet profoundly human companies in history — a place where we can enjoy shaping the future together.Our InvestorsOur vision is supported by esteemed investors such as Y Combinator, Afore Capital, Scribble Ventures, and Pioneer Fund. Our angel investors include leading figures from OpenAI, Anthropic, xAI, and DeepMind, alongside respected founders from Silicon Valley like Siqi Chen (Runway) and Julian Weisser (On Deck).Our FoundersFounded in 2024 by Conor Brennan-Burke and Manu Ebert, Hyperspell is driven by experienced leaders. Conor previously spearheaded growth at Checkr, overseeing a $30 million API product portfolio and earning the title of 'the most helpful founder in YC'.Manu brings over 15 years of expertise in machine learning and AI, having successfully sold two companies and led high-growth engineering teams at Airbnb. Interestingly, he acquired his first .ai domain in 2014, needing to send a fax to the domain authority in Anguilla to do so.About the RoleAs our founding platform engineer, your mission will be to construct the infrastructure that makes Hyperspell feel magical — swift, dependable, and effortlessly scalable. You will be responsible for the foundation upon which our entire product is built, ensuring that when customers entrust us with their data, we uphold their trust.

About the RoleJoin our dynamic team at allinbits as a Platform Engineer, where your expertise will be vital in designing and maintaining the robust infrastructure that supports our cutting-edge projects. Your role will combine technical acumen with strategic insight, ensuring our development and operational environments are finely tuned for optimal performance, reliability, and scalability.We prioritize experience in our team, especially if you have transitioned from a developer role into DevOps or Site Reliability Engineering (SRE). Your capacity to innovate and construct resilient systems will prove invaluable.In this position, you will utilize tools such as Ansible, Docker, and Hashicorp Nomad to enhance our operations.

At Inductive Bio, we believe that drug discovery is fundamentally a design challenge. Chemists invest countless hours, blending experimental data with their intuition to devise molecules aimed at effectively targeting biological challenges while ensuring optimal absorption and safety. This intricate process can span years and incur significant costs, leaving many patient needs for innovative therapeutics unaddressed.Our mission is to revolutionize the way molecules are conceived and developed through advanced software solutions. We are crafting a powerful platform, akin to Figma, supported by robust infrastructure and cutting-edge AI, facilitating seamless collaboration among elite drug discovery teams worldwide. Our platform is currently utilized in over 30 active drug discovery initiatives, with rapid adoption on the horizon. We are proud to be backed by prominent investors at the nexus of technology and biotechnology, with guidance from leading experts in drug discovery.We invite a passionate Frontend Software Engineer with UI/UX design experience to join our dynamic and supportive team. In this role, you will collaborate directly with chemists, ML engineers, and users to craft intuitive products that empower some of the brightest minds in drug chemistry and biology in their quest to discover new therapies. As an early team member in a fast-growing startup, you will have the chance to make a significant impact while expanding your skills and knowledge.

Join Our MissionAt Unlearn, we are revolutionizing clinical development to create smarter trials. Our innovative use of data, artificial intelligence, and digital twins accelerates the process of delivering life-saving treatments to patients. This vision fuels our collaboration with biopharmaceutical companies as we transform the planning, execution, and analysis of clinical trials.We are setting the standard for the future of clinical development by leveraging unparalleled scientific credibility and AI-driven precision, making decision-making clearer and trials more robust. Our goal is not just to disrupt the pharmaceutical landscape but to foster meaningful change.We firmly believe that AI will shape the future of medicine, and we are dedicated to cultivating that future in a responsible and collaborative manner with our clinical development partners.About Our TeamOur team embodies a diverse range of expertise, from machine learning to marketing, yet all Unlearners share core attributes:Ambitious: We embrace challenging goals without hesitation.Disciplined Experimenters: We break down larger objectives into manageable tasks, meeting frequently to monitor progress and iterate swiftly.Gritty: We are resilient; setbacks only motivate us to strive harder.Receptive to New Ideas: We resist complacency and welcome innovative thinking.Storytellers: We prioritize sharing information effectively, ensuring it is engaging and informative.Team-Oriented: Our mission takes precedence over everything; we prioritize the company and team over individual pursuits.Founded in 2017 and headquartered in San Francisco, Unlearn has attracted top-tier investors such as Altimeter, Insight Partners, Radical Ventures, 8VC, DCVC, and DCVC Bio, successfully completing a $50 million Series C funding round in January 2024.If our mission and culture resonate with you, we encourage you to apply.

About UsAt Speak, we are on a mission to transform the way individuals engage with language learning.Learning a new language has the power to transform lives, unlocking opportunities in diverse cultures, careers, and communities. With two billion people globally seeking to learn a language, the most effective method—one-on-one tutoring—remains difficult to access on a large scale and has seen little innovation for decades. Speak is pioneering an AI-driven, human-level tutoring experience that fits in your pocket: a conversation-first platform enabling learners to practice speaking, receive immediate feedback, and advance through meticulously crafted lessons. Our approach provides a comprehensive journey from novice to confident speaker in multiple languages.Launched in South Korea in 2019, Speak has quickly risen to become the leading language learning application in the region, catering to learners across various markets in over 15 languages. As one of the foremost AI companies globally, we have secured over $150 million in venture capital from prominent investors such as OpenAI, Accel, Founders Fund, and Khosla Ventures, with a distributed team operating across San Francisco, Seoul, Tokyo, Taipei, and Ljubljana.About This RoleAs a Platform Engineer at Speak, you will play a pivotal role in enhancing the reliability and resilience of our systems that support the global language learning experience. You will lead initiatives to scale our infrastructure, fortify our platform, and ensure our services are fast, accessible, and dependable for millions of users worldwide.Your work will span our entire tech stack—from Kubernetes on GCP to our Node.js APIs, Postgres, and Redis—creating robust infrastructure and operational tools. You will take charge of incident response, observability, and SLOs, fostering a culture of reliability throughout the engineering organization.With Speak's rapid growth, we are continuously pushing our systems to their limits. This is a unique opportunity to influence the future of our platform as we scale to accommodate the next tenfold increase in users.

Why Join Flux?At Flux, we are simplifying the complexities of hardware development by pioneering the world’s first AI Hardware Engineer. Our mission is to democratize access to cutting-edge hardware technology and transform the global landscape of electronics design and manufacturing.About the PositionAs a Platform Engineer at Flux, you will play a crucial role in ensuring that our platform operates seamlessly. Your work will extend beyond the editor, encompassing essential features such as billing, authentication, onboarding, and integrations.You will be responsible for delivering features that enhance user experience, maintaining operational integrity, and facilitating the scalability of Flux’s platform.Key ResponsibilitiesDevelop and sustain user-centric platform functionalities (billing, authentication, onboarding, settings).Integrate and sustain third-party APIs (e.g., Stripe, Firebase, analytics).Create backend services using TypeScript/Node and frontend components with React.Enhance the reliability and performance of core platform functionalities.Implement standards for observability, logging, and error tracking.Collaborate with cross-functional teams to design APIs that support new products and integrations.Document architecture and best practices pertinent to your domain.Required QualificationsMinimum of 5 years of professional software engineering experience.Proficiency in TypeScript, Node.js, and React is essential.Experience in integrating and maintaining third-party APIs is required.Demonstrated success in deploying full-stack web applications.Familiarity with cloud hosting environments (GCP/AWS/Firebase) and basic CI/CD practices.Strong debugging and cross-system troubleshooting capabilities.Excellent communication skills, both written and verbal; ability to thrive in asynchronous, remote team settings.Preferred QualificationsExperience with multi-tenant SaaS applications or collaborative web platforms.Familiarity with authentication frameworks (OAuth, JWT, Firebase Auth).Experience with observability tools (Sentry, Datadog, Grafana).Background in developing internal tools or administrative dashboards.

Charter:Join a pioneering team dedicated to developing the first precise AI systems for predicting drug toxicity, aiming to replace traditional lab and animal experiments.About Axiom and the role:At Axiom, we are committed to creating advanced AI systems for drug safety and toxicity evaluation. Drug toxicity is a leading cause of failure in drug development, and by addressing this challenge, we can accelerate the delivery of innovative medicines to patients. We are seeking a passionate Data Engineer to lead the design and implementation of pipelines, systems, and tools that transform raw chemical, biological, and clinical data into machine learning-ready datasets and actionable insights for our clients. This role involves close collaboration with our machine learning, laboratory, and product teams to develop literature research and data platforms driven by large language models (LLMs), enhance the inference capabilities of image and graph neural networks, automate ETL processes from various sources, and uphold the integrity of critical datasets that inform key decisions within the organization.What we are looking for:We aim to attract individuals who inspire and elevate our entire team. Ideal candidates will bring high energy, autonomy, and a discerning eye for what truly matters. They should embody a proactive mindset that continuously identifies necessary actions and executes them. Candidates must possess technical excellence, a deep mastery of their craft, and an insatiable curiosity that keeps them at the cutting edge of technology while effectively interfacing across AI, engineering, product, biology, chemistry, and business domains. Although they may have experience in larger tech firms, they seek a challenging adventure that promises significant rewards and satisfaction at the end.What you will be doing:Design and maintain Axiom's core research platform data systems, encompassing ingestion, processing, storage, and serving capabilities.Collaborate with scientists to define their data requirements and develop streamlined APIs for accessing chemical and biological datasets.Architect LLM systems to curate, cleanse, and analyze human clinical trial data, ensuring proper evaluations and observability for these systems.Create distributed systems for executing large-scale LLM tasks that clean and curate biological and clinical data.Establish quality assurance measures, testing tools, and monitoring systems to maintain the accuracy and reliability of data and model outputs.

Founding Platform & Reliability Engineer About OpenArtOpenArt is a revolutionary AI-driven storytelling and visual creation platform utilized by millions around the globe. Our mission is to build the next generation of creative tools powered by advanced AI technology, allowing users to generate videos, visuals, characters, and narratives with speed and creativity never seen before. We envision a future where creativity is inherently AI-native, and we are at the forefront of this transformation. Why Join OpenArt?Be part of a small, dynamic team where senior engineers are responsible for significant systems, not just fragments.Contribute to large-scale projects, with your work impacting millions of users swiftly.Benefit from a founder-led engineering culture where both founders are technical and actively engaged in product and architectural decisions.Work on an AI-native product, crafting how state-of-the-art AI models translate into tangible user experiences.Experience high ownership with minimal bureaucracy, emphasizing judgment, clarity, and speed.Join us during a period of significant growth, with a 7-10X revenue increase over the past two years, and play a pivotal role in scaling the company to new heights. About the RoleWe are seeking a Founding Platform & Reliability Engineer to take charge of the design, scalability, and reliability of our entire infrastructure stack, from high-level architectural choices to hands-on implementation, observability, and cost management.This role is not suited for traditional operators or narrow DevOps specialists. You should be adept at navigating cloud infrastructure, distributed systems, backend services, and developer tools, making practical decisions that optimize product velocity, system reliability, and cost efficiency, particularly in a fast-paced AI-centric landscape.You will collaborate closely with the founders and product engineers to design and refine the platform that powers OpenArt, influencing key decisions like serverless versus containerized architecture, multi-provider AI reliability, and scaling systems for millions of users, while serving as a force multiplier for the entire engineering team. What You’ll DoEstablish and operationalize SLOs/SLIs across essential user journeys (generation, editing, payments/credits, uploads, etc.), utilizing them to guide prioritization (including error budgets).Lead the design and implementation of robust infrastructure solutions that effectively support OpenArt's rapid growth and evolving needs.

Join Perplexity as a skilled Software Engineer, where you will play a pivotal role in developing the next-generation AI Foundation and Platform. Our mission is to transform how individuals search and engage online. In this exciting position, you will contribute to building Perplexity's comprehensive AI data, evaluation, and personalization infrastructure, which underpins nearly all of our agent products.Technology Stack: Spark | AWS Data Stack (S3, RDS, DynamoDB, Docker, EKS, Kinesis) | Pytorch | Databricks | Snowflake | LLM APIsAs we continue to expand our user base and diverse use cases, our data stack ensures that millions around the globe receive fast, personalized answers.

Join Our Team:At Notion, we empower individuals and teams to create stunning tools for their professional journeys. In a landscape filled with countless applications, Notion stands out by providing a cohesive platform that integrates documents, notes, projects, calendars, and emails. With built-in AI capabilities, we streamline workflows and enhance productivity. Our diverse user base, ranging from freelancers to major companies such as Toyota, Figma, and OpenAI, appreciates Notion’s versatility, which aids in saving both time and resources.We believe in the power of in-person collaboration, hence all employees are expected to work from our offices on Mondays, Tuesdays, and Thursdays—our designated Anchor Days. Depending on team requirements, additional in-office days may be necessary.Role Overview:As a Client Platform Engineer, you will spearhead the management of our endpoint infrastructure across macOS, Windows, iOS, and Android. Your mission will be to design and implement scalable, automated solutions that ensure secure deployments and optimize operational efficiency. Collaboration with IT, Security, and Engineering teams will be key as you adopt modern endpoint management practices using automation, Infrastructure-as-Code (IaC), and monitoring strategies.Your Objectives:In this role, you will:Architect, implement, and sustain a high-performance endpoint management infrastructure for macOS, Windows, iOS, and Android, emphasizing top-tier security.Enhance endpoint management through custom software development utilizing industry-standard open source tools and proprietary solutions.Utilize modern Infrastructure-as-Code (IaC) techniques and establish GitOps-driven methods for collaborative fleet management on a large scale.Create and manage CI/CD pipelines for fleet management infrastructure, ensuring deployments across rigorously tested environments in Azure, AWS, and GCP.Promote the adoption of cutting-edge CPE technologies and industry best practices to enhance process scalability and operational efficacy.Collaborate with cross-functional teams to provide seamless endpoint experiences while adhering to stringent security protocols and elevating quality standards.Essential Skills:Strong command of modern programming languages such as Python, Golang, or TypeScript.Proven hands-on experience with Kandji and Microsoft Intune, or equivalent cloud identity management solutions.Demonstrated proficiency in endpoint management and security practices.

At Inductive Bio, we are revolutionizing the drug discovery process by leveraging artificial intelligence to develop predictive models. Scientists traditionally design molecules based on predictions of their potency, safety, and absorption, yet the validation of these predictions through laboratory experiments can be immensely time-consuming and costly. Our innovative approach enables us to create in silico models that accurately forecast molecular behavior, allowing scientists to make informed decisions more rapidly, ultimately accelerating the delivery of safer, high-quality medicines to patients. Our extensive proprietary dataset supports our ongoing application of these advanced methodologies in numerous active drug discovery initiatives. With backing from prominent investors straddling both biotechnology and technology sectors, and guidance from esteemed drug discovery experts, we are on the cusp of a significant transformation in the industry.We are looking for passionate Machine Learning Scientists to join our dynamic and collaborative team. In this role, you will have the chance to innovate on algorithms, collaborate with leading drug discovery scientists, and apply your work directly to pioneering drug programs at some of the world’s most innovative biotech companies. As one of the early machine learning scientists at Inductive Bio, you will have the opportunity to make a substantial impact while evolving alongside our rapidly growing company.Key Responsibilities:Develop and refine machine learning models to predict molecular properties from chemical structures.Create innovative algorithms for generating novel molecule ideas.Build intelligent agents that synthesize complex data from drug programs to guide molecular optimization.Engage deeply with our unique proprietary datasets to iterate on modeling concepts and enhance model performance.Collaborate closely with chemists and software engineers to seamlessly integrate models into our software platform used by drug discovery scientists worldwide.Construct and optimize scalable infrastructure for model training, deployment, and monitoring.Interact directly with scientific users to gather feedback and improve the product.Contribute significantly to product strategy and the overall direction of the company.

Join Us at AirwallexAirwallex is redefining the financial landscape with our cutting-edge unified payments and financial platform tailored for global enterprises. Our innovative mix of proprietary infrastructure and software empowers over 200,000 businesses around the globe – including prominent names like Brex, Rippling, Navan, Qantas, and SHEIN – to seamlessly manage their business accounts, payments, spend management, treasury, and more, all on a single integrated platform.Founded in Melbourne, we pride ourselves on a diverse team of over 2,000 forward-thinking professionals across 26 offices worldwide. With a valuation of $8 billion and backing from top-tier investors such as T. Rowe Price, Visa, Mastercard, Robinhood Ventures, Sequoia, Salesforce Ventures, DST Global, and Lone Pine Capital, Airwallex is at the forefront of crafting the global payments and financial ecosystem of the future. If you're ready to embark on a transformative career journey, we invite you to join our mission.What We Look ForWe seek builders who embody an entrepreneurial spirit and are eager to make a tangible impact. You possess deep expertise in your field and a keen intellect, driven by our mission and operating principles. You are quick to act, possess sound judgment, and approach challenges with curiosity, balancing the swift execution of ideas with thorough analysis.Collaboration is key; you excel at transforming innovative concepts into viable products while ensuring that tasks are executed seamlessly from inception to completion. Leveraging AI, you work efficiently and creatively tackle complex challenges alongside exceptional colleagues, paving the way for your professional advancement as we shape the future of global finance. If this resonates with you, let’s create what’s next together.Your RoleAs the Engineering Director for the GTPN (Global Treasury and Payment Network) Team, you will be pivotal in enhancing Airwallex's payment infrastructure. Your focus will be on expanding the capabilities and user experience of our global treasury and payment network while developing innovative payment solutions grounded in a robust financial architecture. We are looking for a highly skilled and proactive leader to guide this dynamic team as we continue to broaden our global footprint.In this role, you will supervise multiple feature teams across Transfers, Client Treasury, and GTPN Infrastructure. Your technical prowess as an engineer, combined with your leadership skills, strategic product insights, and business acumen, will distinguish you as a leader in our organization.

At Browserbase, our Platform Services team is integral to delivering seamless and robust backend services and APIs that empower our products. We focus on providing both internal and external developers with a fast, reliable, and user-friendly foundation. From crafting elegant interfaces to managing vital services in production, our team is at the core of Browserbase’s operations.ResponsibilitiesDesign, develop, and maintain backend services and APIs essential for Browserbase’s diverse product offerings.Create service architectures that prioritize reliability, clarity, maintainability, and extensibility.Collaborate with product and engineering teams to understand requirements and deliver intuitive APIs and service abstractions.Oversee projects from initiation to completion, including design, implementation, rollout, monitoring, and ongoing maintenance.Enhance developer experience with comprehensive documentation, tools, and thoughtful interface design.Diagnose and resolve operational challenges in production systems.Contribute to establishing standards for service architecture, API design, testing, and operational excellence.

Join Flux: Revolutionizing Hardware EngineeringAt Flux, we are transforming the landscape of hardware engineering with our pioneering AI Hardware Engineer. Our mission is to empower innovators worldwide to design and build cutting-edge hardware effortlessly.Your RoleAs a Senior Platform Engineer, you will be at the forefront of developing robust systems that enhance the Flux platform. You'll be responsible for crucial functionalities beyond the editor, including billing, authentication, onboarding, and integrations.Your contributions will directly impact every user, ensuring seamless operations and enabling Flux to scale efficiently.Core ResponsibilitiesDevelop and sustain user-centric platform features, such as billing, authentication, onboarding, and settings.Integrate and manage third-party APIs including Stripe, Firebase, and various analytics tools.Create backend services using TypeScript/Node.js and develop frontend components with React.Enhance the reliability and performance of essential platform workflows.Establish standards for observability, logging, and error tracking.Collaborate with cross-functional teams to design APIs that enable new products and integrations.Document architecture and best practices within your domain.

Join our innovative team at Harvey as a Software Engineer focusing on our AI Platform. In this role, you will leverage cutting-edge technologies to develop and enhance AI-driven solutions that empower our users and transform industries. You will collaborate with cross-functional teams to design robust software architectures and implement scalable solutions that meet the needs of our diverse clientele.

Join middesk as a Software Engineer specializing in our Data Platform, where you will play a pivotal role in building robust systems that empower our data-driven initiatives. You will collaborate with cross-functional teams to design, implement, and optimize data solutions that enhance our products and services.