About the job
This Senior Research & Operations Technician role is based at Orchard Therapeutics' research facility in Hammersmith, London, and reports to the Executive Director of Translational Research. The position supports the Translational Research & Development teams, focusing on laboratory operations and technical oversight within the field of gene-modified hematopoietic stem cell (HSC) therapies.
Role overview
The technician manages core activities related to Lentiviral vector and Cell & Gene therapy analytical methods. Responsibilities include operational laboratory management and ensuring the smooth functioning of research infrastructure. The role requires a strong background in molecular biology and analytical techniques, with a preference for experience in Lentiviral vector production and the cell and gene therapy sector.
Key responsibilities
- Lead and optimize daily operations and infrastructure of the research laboratories to support R&D objectives.
- Manage and mentor the Translational Research Core Technical team, including assignment distribution, training, and staff development.
- Uphold quality and safety standards in the research environment.
- Collaborate with Translational Research Leadership, Facility Management, and Global Technical Operations to develop and implement laboratory policies and procedures.
- Monitor compliance and contribute to continuous improvements in research quality, data integrity, and laboratory practices.
Requirements
- Solid foundation in molecular biology and analytical methods.
- Experience in Lentiviral vector production and cell & gene therapy is strongly preferred.
- Demonstrated ability to lead and mentor technical staff.
This position plays a central role in supporting Orchard Therapeutics' mission to advance gene therapy for rare genetic disorders through strong laboratory management and technical leadership.

