Senior Research Associate in Therapeutic Discovery

Your Role at Lila Sciences As a key contributor to our Physical Sciences division, you will focus on advancing the field of in silico materials discovery techniques. Your responsibilities will involve designing autonomous workflows and data-driven pipelines that effectively integrate simulation with artificial intelligence. You will lead the development of strategies that empower agents to analyze simulation data, derive hidden insights, and facilitate hypothesis generation and materials design. Your innovative approach will enhance our utilization of simulation outputs for discovery, fostering a seamless integration of physics-based modeling with AI reasoning systems. Collaboration with specialists in simulation, AI agents, and experimental automation will be pivotal as we strive to redefine the landscape of digital discovery. Key Contributions Create cutting-edge workflows for in silico materials discovery that link physics-based simulations and generative AI models. Develop intelligent systems where AI agents autonomously design, execute, interpret, and optimize simulations. Establish frameworks that maximize the utility of simulation data for prediction, inference, and discovery, with features like automatic data extraction and model training. Prototype and assess novel paradigms for simulation-aware agents that learn from and interact with scientific simulations. Design data structures, metadata specifications, and APIs to ensure smooth information transfer among simulations, machine learning models, and experimental data repositories. Build scalable, modular workflows that connect electronic structure, atomistic, and mesoscale simulations with AI-driven reasoning and hypothesis generation. Work alongside computational scientists, machine learning professionals, and platform engineers to integrate in silico discovery pipelines into Lila’s overarching scientific superintelligence framework. Qualifications for Success PhD or equivalent experience in Computer Science, Materials Science, Chemistry, Physics, Applied Mathematics, or related fields. Strong background in in silico materials discovery, computational materials modeling, and/or simulation workflow design. Familiarity with large language models and their applications in scientific research. Experience in developing AI-driven or agentic workflows for scientific automation and discovery. Proficient programming skills in Python and scientific computing libraries.

Make an Impact at Lila Sciences As a pivotal member of our Physical Sciences division, you will spearhead the design and implementation of cutting-edge simulation methodologies aimed at modeling transport phenomena, kinetics, rare events, and reaction networks. Your innovative approaches will be integrated with artificial intelligence platforms to facilitate groundbreaking materials discovery. Your contributions will be essential in predicting, designing, and managing the behaviors of intricate materials and molecular systems, leveraging the power of agentic AI. Collaborating with our diverse teams, including experts in machine learning and materials science, you will help bridge theoretical research and practical experimentation. What You Will Create Enhance and develop molecular dynamics and Monte Carlo algorithms to effectively capture rare events, non-equilibrium processes, transport phenomena, and intricate reaction networks. Create scalable simulation workflows that merge statistical mechanics techniques with machine-learned interatomic potentials and agentic AI systems. Devise methods for synchronizing dynamic simulations with experimental observations to enable automated lab verification and discovery. Work collaboratively with computational scientists, machine learning specialists, and platform engineers to elevate the accuracy and scalability of simulation-driven material discoveries. Establish reproducible and modular software pipelines for statistical mechanics and dynamics simulations, optimized for high-performance computing and cloud environments. Qualifications for Success A PhD or equivalent research/industry experience in Physics, Chemistry, Chemical Engineering, Mechanical Engineering, Applied Mathematics, or related fields. A robust background in statistical mechanics, free energy calculations, reaction mapping, non-equilibrium dynamics, and rare-event sampling techniques. Proven expertise in molecular dynamics, Monte Carlo simulations, and/or kinetic simulation software frameworks (e.g., LAMMPS, GROMACS, OpenMM, HOOMD). Strong programming skills and experience in scientific computing (Python, C/C++, MPI, CUDA, etc.). Experience in executing and automating simulations on high-performance computing (HPC) and/or cloud platforms at scale. Bonus Qualifications A solid publication record showcasing the application of advanced statistical mechanics or dynamics simulations to molecular and materials systems, including molecular/biomolecular systems and solid-state materials and interfaces. Experience in integrating dynamics simulations with data-driven, AI-based, and/or agentic frameworks.

Join our dynamic team as an Associate Scientist II, where you will contribute to innovative research and development initiatives. You will work collaboratively with cross-functional teams to advance scientific projects and support our mission to drive breakthroughs in biotechnology.

Join AbbVie as a Senior Scientist II in our Assay Development team, focusing on innovative research in Discovery Psychiatry. This role involves designing, developing, and optimizing assays to advance our understanding of psychiatric disorders. You will collaborate with cross-functional teams to drive research initiatives and contribute to the discovery of effective treatments.The ideal candidate will possess strong scientific expertise, a passion for psychiatric research, and the ability to thrive in a dynamic environment.

We are seeking a motivated and detail-oriented Scientist I to join our dynamic team in Cambridge. The ideal candidate will have a strong background in scientific research, with a passion for innovation and problem-solving. This entry-level role offers an exciting opportunity to contribute to groundbreaking projects and advance your career in a collaborative environment.

Your Impact at Lila Join our innovative Physical Sciences team as a Research Scientist, where you'll spearhead the development of cutting-edge generative modeling techniques to address significant challenges in materials science. Collaborate with a diverse team of machine learning experts, software engineers, and materials scientists to create and implement generative models tailored to Lila’s distinctive materials design needs. This role not only advances the forefront of scientific research but also allows you to witness the tangible impact of your work on materials being refined in our experimental facilities on a daily basis. What You’ll Be Building Generative Models: Create and deploy generative models, including Diffusion and flow-based models, alongside advanced sampling methods to solve diverse materials design challenges. Data Representation: Innovate architectures and approaches that incorporate physics-informed constraints and domain knowledge to model materials across a wide chemical space for real-world applications. Real-World Validation & Deployment: Develop and verify datasets, frameworks, and methodologies for validating generative models with experimentally realized materials. Collaborate with software engineers and product managers to implement these solutions. Cross-Functional Partnership: Engage with R&D leadership, product managers, and automation specialists to translate scientific inquiries into data requirements and modeling strategies. What You’ll Need to Succeed Proficient in Python and deep learning frameworks with experience in end-to-end workflow deployment. Familiarity with contemporary generative modeling techniques, including diffusion models and geometric deep learning, and their applications in scientific disciplines such as materials science, chemistry, and biology. A foundational understanding of materials science, physics, and chemistry, and the ability to incorporate these principles into generative model design. A self-motivated and independent thinker with keen attention to detail. Demonstrated experience in industry or notable academic achievements. Strong communication and presentation skills, with the ability to convey complex technical information effectively. Aspirations to collaborate with highly skilled teams in a dynamic, entrepreneurial, and technical environment.

Your Role at Lila SciencesJoin our innovative Physical Sciences division, where you will spearhead the development of intelligent agent-driven systems designed to enhance AI-accelerated and AI-orchestrated process engineering across diverse industrial applications. In this pivotal role, your mission will be to create methodologies empowering AI agents to reason, design, simulate, optimize, and operate complex physical and chemical processes using both traditional and machine learning-driven process engineering tools. You will focus on building agentic infrastructures that facilitate AI systems in planning and executing multi-step process engineering workflows, which include process synthesis, flowsheet generation, steady-state and dynamic simulation, control strategy design, and techno-economic evaluation. Your contributions will significantly influence how Lila's scientific superintelligence addresses real-world challenges through closed-loop autonomous process engineering.Your ContributionsDesign and implement agentic frameworks supporting comprehensive process engineering workflows, encompassing process setup, simulation, optimization, and analysis.Create AI agents capable of autonomously planning, executing, and refining process engineering tasks utilizing existing tools such as steady-state and dynamic simulators, optimizers, and data systems.Investigate agentic strategies for advanced objectives, including process intensification, control co-design, real-time optimization, and closed-loop learning informed by operational data.Enhance the robustness, interpretability, and reproducibility of agent-driven process engineering workflows; develop internal tools for debugging, observability, validation, and auditability.Collaborate with interdisciplinary teams to apply agentic process engineering across a wide range of industrial applications.

COMPANY DESCRIPTION We are a pioneering start-up dedicated to transforming the landscape of chemical discovery. Our innovative platform integrates artificial intelligence with a state-of-the-art laboratory discovery pipeline to redefine molecular formulation development. Our interdisciplinary team is exploring uncharted chemical territories, facilitating significant advancements in drug delivery, agricultural formulations, and sustainable, high-performance industrial chemicals. Backed by Flagship Pioneering, a leader in biotechnology origination, we have fostered over 115 scientific ventures in 25 years, generating more than $20 billion in aggregate value, 500+ patents, and over 50 clinical trials for groundbreaking therapeutic agents. THE ROLE We are on the lookout for a passionate and skilled Senior Research Associate or Associate Scientist to enhance our formulation discovery platform by characterizing biomolecules. This position involves utilizing a range of biophysical and biochemical methodologies to analyze the effects of formulations on biomolecular integrity, aggregation, and functional stability. You will collaborate closely with chemists and machine-learning experts to produce high-quality experimental data that drives formulation design and predictive modeling initiatives. The ideal candidate will possess a solid background in biochemistry, structural biology, or biopolymer engineering, complemented by practical experience with analytical instrumentation for biomolecular characterization. KEY RESPONSIBILITIES Conduct experiments assessing biomolecular stability and solubility across various formulation conditions. Evaluate cargo structural integrity and folding utilizing circular dichroism (CD) spectroscopy and complementary biophysical techniques. Measure biomolecular interactions and stability through spectroscopy, dynamic light scattering, and electrophoretic methods. Prepare samples for diverse external workflows to evaluate molecular integrity and degradation. Experimental Pipeline Support Collaborate with formulation chemists to investigate cargo-formulation interactions across different experimental contexts. Generate high-quality experimental datasets to assist internal modeling and data analysis processes. Support laboratory instrumentation maintenance and troubleshooting. Maintain organized laboratory records, analyze results, and communicate findings effectively to cross-functional teams.

We are seeking a highly motivated and detail-oriented Research Scientist to join our innovative team in Cambridge. In this role, you will conduct groundbreaking research, analyze data, and contribute to the development of new solutions in our field. You will work collaboratively with cross-functional teams to drive projects from ideation to execution, ensuring scientific rigor and excellence.

Role Overview AbbVie is hiring a Scientist I to join the Immunology Discovery group in Cambridge. This is an entry-level role focused on research that supports new therapies in immunology. The team values creative problem-solvers who want to help drive scientific progress. What You Will Do Collaborate with scientists on research projects in immunology Apply modern laboratory techniques to investigate immune system pathways Contribute data and insights to support the development of new therapies Work as part of a team committed to advancing scientific understanding Location This position is based in Cambridge.

Your Impact at Lila Join our dynamic and innovative AI safety team at Lila Sciences, where we prioritize talent and agency to mitigate risks associated with scientific superintelligence. Our mission is to craft and execute a tailored safety strategy that aligns with our unique objectives and deployment methods. This role involves creating technical safety strategies, engaging with the broader scientific community, and producing critical technical documentation, including evaluations focused on risk and capability assessments. What You’ll Be Creating Design and implement capability evaluations to assess scientific risks, particularly from cutting-edge scientific models integrated with automated physical laboratories across biological and physical sciences. Lead and coordinate threat modeling sessions with both internal and external scientific experts, keeping abreast of emerging technologies and use cases. Develop and manage high-quality training and testing datasets for evaluations and safety systems. Analyze risks associated with Lila’s capabilities and their interactions with the broader ecosystem of general-purpose frontier models and specialized scientific tools. Contribute to high-quality research initiatives focused on scientific capability evaluation and restriction as needed. Assist with external communications regarding Lila’s safety initiatives. What You’ll Need to Succeed A PhD in biological sciences (e.g., molecular biology, virology, computational biology) or physical sciences (e.g., materials science, physics, chemistry, or chemical engineering), or similar experience. Proficient in scientific computing related to biological or physical sciences. Familiarity with dual-use research and dissemination issues within relevant safety, regulatory, and governance frameworks (e.g., export control, biological and chemical conventions). Exceptional communication skills to convey complex technical concepts to non-expert audiences effectively. Proven ability to lead internal and external teams in developing Lila's perspective on biological and physical risks. Demonstrated capacity to collaborate with cross-functional stakeholders (science, AI, product, policy) in a complex environment.

We are seeking a passionate and detail-oriented Scientist I to join our innovative team at Integrated Resources Inc. This entry-level position offers a fantastic opportunity to contribute to groundbreaking research and development projects. You will work closely with experienced scientists to support various laboratory activities, including experimental design, data collection, and analysis.

We are seeking a highly motivated and detail-oriented Research Scientist to join our innovative team in Cambridge. As a key member of our research department, you will be responsible for conducting cutting-edge experiments, analyzing data, and contributing to groundbreaking discoveries in your field. You will collaborate with a diverse group of scientists and researchers to drive projects that align with our mission of advancing scientific knowledge.

Join our team at Integrated Resources Inc. as an Associate Research Scientist, where you will contribute to cutting-edge research projects that impact real-world applications. We are looking for passionate individuals eager to innovate and collaborate in a dynamic environment. In this role, you will support senior scientists in the design and execution of experiments, analyze data, and contribute to publications. This is a fantastic opportunity to grow your career in scientific research.

Join Integrated Resources Inc. as an Associate Scientist I, where you will contribute to innovative scientific research and development projects. As a pivotal part of our team, your role will involve conducting experiments, analyzing data, and collaborating with multidisciplinary teams to advance our scientific objectives.

Role overview Harvard University seeks a Principal Research Scientist for the Sciences - Chemistry and Chemical Biology department in Cambridge. This role leads research efforts, working closely with faculty and other researchers to advance scientific understanding in chemistry and chemical biology. What you will do Direct research projects in chemistry and chemical biology Collaborate with faculty and research teams on experimental design and analysis Apply innovative methods to address complex scientific questions Contribute to scientific publications and presentations

AbbVie is seeking a talented and motivated Associate Scientist II or Scientist I to join our dynamic In Vivo Pharmacology team in Cambridge. As part of our innovative research environment, you will play a crucial role in advancing our understanding of pharmacological mechanisms through in vivo studies. This position offers an exciting opportunity to contribute to groundbreaking research that has the potential to transform patient care.

We are seeking a dedicated and passionate Associate Scientist II to join our team in Cambridge. In this role, you will contribute to cutting-edge research and development initiatives, supporting our mission to innovate and enhance scientific solutions. You will work collaboratively with a multidisciplinary team to conduct experiments, analyze data, and interpret results, driving projects forward and contributing to significant advancements in our field.

Join our team at Integrated Resources, Inc. as an Associate Scientist II, where you will contribute to cutting-edge research and development in a dynamic and collaborative environment. In this role, you will utilize your scientific expertise to support various projects and drive innovation.