About the job
COMPANY DESCRIPTION
We are a pioneering start-up dedicated to transforming the landscape of chemical discovery. Our innovative platform integrates artificial intelligence with a state-of-the-art laboratory discovery pipeline to redefine molecular formulation development. Our interdisciplinary team is exploring uncharted chemical territories, facilitating significant advancements in drug delivery, agricultural formulations, and sustainable, high-performance industrial chemicals.
Backed by Flagship Pioneering, a leader in biotechnology origination, we have fostered over 115 scientific ventures in 25 years, generating more than $20 billion in aggregate value, 500+ patents, and over 50 clinical trials for groundbreaking therapeutic agents.
THE ROLE
We are on the lookout for a passionate and skilled Senior Research Associate or Associate Scientist to enhance our formulation discovery platform by characterizing biomolecules. This position involves utilizing a range of biophysical and biochemical methodologies to analyze the effects of formulations on biomolecular integrity, aggregation, and functional stability. You will collaborate closely with chemists and machine-learning experts to produce high-quality experimental data that drives formulation design and predictive modeling initiatives. The ideal candidate will possess a solid background in biochemistry, structural biology, or biopolymer engineering, complemented by practical experience with analytical instrumentation for biomolecular characterization.
KEY RESPONSIBILITIES
- Conduct experiments assessing biomolecular stability and solubility across various formulation conditions.
- Evaluate cargo structural integrity and folding utilizing circular dichroism (CD) spectroscopy and complementary biophysical techniques.
- Measure biomolecular interactions and stability through spectroscopy, dynamic light scattering, and electrophoretic methods.
- Prepare samples for diverse external workflows to evaluate molecular integrity and degradation.
Experimental Pipeline Support
- Collaborate with formulation chemists to investigate cargo-formulation interactions across different experimental contexts.
- Generate high-quality experimental datasets to assist internal modeling and data analysis processes.
- Support laboratory instrumentation maintenance and troubleshooting.
- Maintain organized laboratory records, analyze results, and communicate findings effectively to cross-functional teams.

