Senior/Principal Scientist - Human-Computer Interaction (HCI)

ABOUT PIONEERING INTELLIGENCE Pioneering Intelligence builds on the legacy of Flagship Pioneering, leveraging the latest advancements in artificial intelligence, machine learning, and data analytics to expedite groundbreaking research and establish a portfolio of AI-centric companies. As an integral part of Flagship’s innovative model that merges science, entrepreneurship, and capital, we transform revolutionary ideas into transformative enterprises, enhancing the AI breakthroughs occurring within the realms of human health, sustainability, and beyond. THE ROLE Pioneering Intelligence represents a strategic initiative of Flagship Pioneering, dedicated to positioning our organization at the forefront of global innovation through the fusion of human, machine, and nature’s intelligence – a concept we refer to as Polyintelligence. We are currently on the lookout for a Principal Product Manager to collaborate across various disciplines including UX design, AI research, engineering, legal, communications, marketing, and scientific research teams, as well as venture creation units, to address the most significant challenges in AI within the life sciences sector. We are establishing a state-of-the-art digital infrastructure that integrates computational science, AI/ML technologies, knowledge engineering, data platforms, and workflow automation. These capabilities are essential in supporting Flagship’s distinctive approach to exploring uncharted territories and translating scientific insights into transformative enterprises. The Principal Product Manager, Agentic AI will be a key individual contributor responsible for owning a specific product area from conception to execution, translating intricate user and scientific requirements into a coherent strategy, quantifiable outcomes, and widely adopted solutions aligned with our business objectives. As part of a multidisciplinary team, you will closely partner with scientists and business stakeholders to drive impactful innovations from agentic systems that redefine workflows and business capabilities within a dynamic startup environment. KEY RESPONSIBILITIES Own and articulate the product vision, strategy, and roadmap. Define Objectives and Key Results (OKRs) and drive measurable outcomes. Lead discovery processes with scientists, synthesize insights, and develop wireframes. Facilitate cross-functional decision-making and alignment among machine learning, engineering, and scientific stakeholders. Drive product adoption, including spearheading user enablement initiatives.

Join Cambridge Mobile Telematics (CMT), the globe’s leading telematics service provider, dedicated to enhancing road safety for drivers worldwide. Our innovative AI-powered platform, DriveWell Fusion®, collects sensor data from millions of IoT devices—including smartphones, proprietary Tags, connected vehicles, dashcams, and third-party devices—and integrates it with contextual data to provide a comprehensive overview of vehicle and driver behavior. Auto insurers, automakers, commercial mobility firms, and public sector organizations leverage insights from CMT’s platform to enhance risk assessment, optimize safety, streamline claims, and develop driver improvement initiatives. With headquarters in Cambridge, MA, and additional offices located in Budapest, Chennai, Seattle, Tokyo, and Zagreb, we are committed to safeguarding tens of millions of drivers globally every day.As the Principal Product Manager, you will spearhead the strategy and execution of our Drivewell Crash product, with an initial emphasis on Openroad—a direct-to-consumer mobile application that delivers advanced crash detection and assistance. Utilizing state-of-the-art technology, the app provides real-time alerts, automatic emergency response, and comprehensive incident reports. We are seeking a self-motivated, imaginative, and customer-centric mobile app Product Manager to take charge of the app and drive its continuous innovation, ensuring it remains a reliable resource for our users.CMT is in search of a collaborative, customer-focused, and inventive Principal Product Manager II, Crash & Claims who is eager to contribute to our mission of making roads safer by improving driver behavior!

Role Overview Lila Sciences is seeking a Principal Engineer with expertise in AI Security for its Cambridge, MA office. This senior individual contributor will help define and drive the technical strategy to secure AI applications across the organization. The role involves close collaboration with IT and business teams to ensure AI tools and platforms are implemented safely and in compliance with internal and external requirements. Securing both third-party and in-house AI tools is central to this position. The work will focus on protecting sensitive data, intellectual property, and scientific processes as AI becomes increasingly embedded in Lila's operations. What You Will Do Enterprise AI Security Strategy: Develop and roll out security controls and guidelines for using AI tools throughout the company, covering LLM APIs and SaaS AI platforms. AI Gateway & Agentic Gateway Security: Design and enforce controls for AI gateways, monitoring and managing access to AI systems. Ensure agentic workflows are secured with strong identity and authorization measures. AI Red Teaming & Adversarial Testing: Lead red teaming and adversarial testing efforts to uncover vulnerabilities in AI usage, such as prompt injection and data exfiltration risks. Data Protection for AI Usage: Establish and maintain safeguards to prevent sensitive data exposure through AI systems, with a focus on input/output filtering and secure data management. Multi-Layer AI Security: Integrate AI security practices with the organization's broader security framework, maintaining visibility and control over AI service access and data flows. AI Threat Modeling: Build and maintain threat models tailored to enterprise AI applications, addressing risks like data leaks and unauthorized agent actions. Vendor & Platform Security: Assess and advise on secure integration of third-party AI vendors, with close attention to their data handling practices and model behavior.

ABOUT PIONEERING INTELLIGENCE Pioneering Intelligence is a forward-thinking initiative that builds upon Flagship Pioneering's rich history of establishing groundbreaking scientific and computational enterprises. By leveraging cutting-edge advancements in artificial intelligence, machine learning, and data science, we aim to accelerate fundamental research and cultivate a dynamic portfolio of AI-first companies. As an integral part of Flagship's unique model that intertwines science, entrepreneurship, and investment, we transform revolutionary concepts into impactful companies, enhancing AI innovations that contribute to human health, sustainability, and more. THE ROLE We are on the lookout for a Principal Scientist specializing in Embedded Machine Learning and Computational Methods to spearhead various AI/ML and computational initiatives across early-stage ventures within our company origination framework. Your responsibilities will include defining and executing practical AI strategies, overseeing the development of methodologies and platforms (including systems design, drug design, molecular modeling, systems biology, protein design, and LLM-based workflows), and ensuring a high standard of rigor in model development, benchmarking, scaling, and reporting. You will also manage cross-functional teams as necessary, influence the strategic direction of our initiatives, and represent Pioneering Intelligence to venture teams and external collaborators. The ideal candidate is a self-motivated individual with a diverse skill set, capable of transitioning seamlessly from protein design to mass spectrometry or docking pipelines, and then creating LLM-based agents to streamline scientific workflows.

Join lilasciences as a Product Lead specializing in Software and Applied AI, where you will spearhead innovative projects that leverage cutting-edge AI technologies. In this pivotal role, you will collaborate with cross-functional teams to define product vision, strategy, and execution, ensuring alignment with user needs and market trends.

Location: Cambridge, MA (Eastern Time / UTC -4) Relocation package available Relocation package: AvailableStart date: ASAPLanguages: English (required)About the RolePragmatike is seeking a highly skilled Principal AI/ML Engineer to join a rapidly growing AI startup recognized as a Top 10 GenAI company by GTM Capital, founded by researchers from MIT CSAIL.In this pivotal role, you will become an integral part of our elite AI engineering team, responsible for architecting, developing, and deploying advanced AI systems utilized by Fortune 500 clients. Your technical expertise will drive the development of essential ML components while collaborating closely with AI researchers, platform engineers, and product teams to ensure the delivery of scalable, production-ready AI solutions.This position is tailored for seasoned AI/ML engineers with a proven track record of building and deploying models in production settings, eager to work at the nexus of research-grade AI and practical systems engineering.Key ResponsibilitiesDesign, construct, train, and refine machine learning and deep learning models for production deploymentLead the successful deployment of ML models into robust, scalable production environmentsArchitect training, inference, and evaluation pipelines for both structured and unstructured datasetsOwn the performance, reliability, scalability, and lifecycle management of ML modelsDrive experimentation, model iteration, and performance benchmarking initiativesImplement and uphold high-quality ML codebases primarily in PythonMonitor, troubleshoot, and enhance live production modelsCollaborate with platform, backend, and infrastructure teams to ensure seamless system integrationContribute to technical direction, architecture decisions, and AI roadmap strategiesMentor junior engineers and foster a culture of technical excellence within the teamDesired QualificationsBachelor’s, Master’s, or PhD in Computer Science, Engineering, Mathematics, or a related discipline7+ years of relevant professional experience in AI/ML, data science, or applied machine learning rolesDemonstrated experience in deploying ML systems in production environmentsStrong proficiency in Python and familiarity with machine learning frameworksExcellent problem-solving skills and a passion for innovation in AI

EverQuote is actively seeking a Senior Product Manager to join our Site Experiences team. In this key position, you will influence and enhance our consumer-facing experiences and the foundational infrastructure of EverQuote’s marketplace platform. Your primary objective will be to ensure seamless, scalable, and high-performing site functionality that enhances engagement and value for both consumers and insurance providers.This role will initially emphasize the development of EverQuote’s new upper funnel platform, contributing to a brand-centric, AI-optimized content and quoting experience. You will engage in a combination of front-end experiences, modular infrastructure, SSR optimization, SEO, and quote APIs, ensuring our site remains discoverable, distinctive, and conversion-ready in the evolving landscape of AI-driven discovery.This is a hybrid position that requires in-office attendance several days a week.The base salary range for this full-time hybrid role is $160,000 to $175,000. Initial salaries will typically align with the lower end of the provided range. Employees may also qualify for company variable compensation or equity programs based on their specific role, level, and responsibilities.

ABOUT PIONEERING INTELLIGENCEPioneering Intelligence extends Flagship Pioneering's tradition of launching innovative scientific and computational initiatives. By leveraging the latest advancements in AI, machine learning, and data analytics, we aim to expedite fundamental research and build a diverse portfolio of AI-first companies. As a key player in Flagship's integrated approach to science, entrepreneurship, and investment, we transform groundbreaking concepts into transformative enterprises that enhance AI innovations in human health, sustainability, and more.THE ROLEWe are on the lookout for a Principal Scientist specializing in Embedded Machine Learning and Computational Techniques to spearhead various AI/ML and computational initiatives across early-stage ventures in our company origination process. You will be responsible for defining and executing practical AI strategies, overseeing the development of methodologies and platforms such as systems design, drug design, molecular modeling, systems biology, protein design, and LLM-driven workflows while ensuring the utmost rigor in model development, benchmarking, scaling, and reporting. You will manage cross-functional contributors as necessary, influence the strategic direction of the company, and represent Pioneering Intelligence to venture teams and external partners. The ideal candidate is a proactive, deep thinker who can seamlessly transition between protein design one week and mass spectrometry or docking pipelines the next, while also developing LLM-based agents to automate scientific workflows.

POS-4092 Team and Product Focus The Data Hub team at HubSpot connects scattered data sources to deliver practical insights for Revenue Operations, marketing, sales, and customer teams. By integrating information from various channels and tools, the team improves data quality and makes this data actionable within HubSpot. This enables teams to run AI-powered demand generation, optimize campaigns, and produce reliable reports, without requiring deep expertise in data systems. Product engineering here blends data engineering, machine learning, applied AI, and market strategy. The group prioritizes reliability, cost efficiency, and scalability, while always considering usability for marketers and sales professionals. Role Overview HubSpot is seeking a Lead Principal Software Engineer to steer the next phase of Data Hub's development. This platform is evolving into the central engine for data-driven demand generation company-wide. Key Responsibilities Take ownership of critical components in the data lake and analytics architecture, working with technologies such as Iceberg, Spark, and both batch and streaming data pipelines. These systems underpin large-scale demand generation, segmentation, and scoring. Design and refine data systems to achieve the right balance between cost, latency, data freshness, and reliability. Apply principles like the CAP theorem, efficient partitioning, and thoughtful storage layout to guide decisions. Collaborate closely with Product Management, product analytics, and go-to-market leaders to deliver solutions that drive business outcomes: improved lead scoring, enhanced funnel visibility, audience segmentation, and campaign attribution for marketing and sales. Contribute to transforming Data Hub into an AI-powered platform, aiming for curated, always-available datasets that support AI agents and reporting tools, eliminating the need for manual integrations or custom pipelines. This is a hands-on principal engineering position. The role involves building systems, working alongside product and design, and amplifying the impact of HubSpot's broader engineering community.

Join AECOM as an Employers Agent, where you will play a pivotal role in managing and overseeing various construction projects. You will be the key point of contact between clients and contractors, ensuring that projects are delivered on time, within budget, and to the highest quality standards. Your expertise will help facilitate communication, resolve issues, and maintain solid working relationships with all stakeholders involved.

ABOUT PIONEERING INTELLIGENCE Pioneering Intelligence continues the legacy of Flagship Pioneering by creating innovative scientific and computational ventures. Utilizing advancements in AI, machine learning, and data analytics, our mission is to expedite fundamental research and establish a diverse portfolio of AI-first companies. We integrate science, entrepreneurship, and capital to transform groundbreaking concepts into impactful companies, furthering AI advancements in human health, sustainability, and more. THE ROLE We are on the lookout for a Principal Scientist in Embedded Machine Learning/Computational to spearhead multiple AI/ML and computational projects within early-stage ventures as part of Flagship’s origination process. Your responsibilities will include defining and executing effective AI strategies, leading method and platform advancements (such as systems design, drug design, molecular modeling, systems biology, protein design, and LLM/agentic workflows), and ensuring excellence in model development, benchmarking, scaling, and reporting. You'll collaborate with cross-functional teams, shape the direction of the company, and represent Pioneering Intelligence to both venture teams and external partners. The ideal candidate is a proactive deep diver, capable of transitioning from protein design to mass spectrometry or docking pipelines, and then developing LLM-based agents to streamline scientific workflows.

POS-31591About Our TeamThe Prospecting Solutions team is revolutionizing the way B2B SMB and mid-market sales teams cultivate their pipeline. The current outbound sales approach is often inefficient and outdated, with representatives dedicating excessive time to research, tool integration, and uncertain contact strategies. Our focus transcends mere outreach execution; we prioritize intelligent sourcing, prioritization, and trust.This team is developing a comprehensive, signal-driven prospecting ecosystem that aligns with contemporary B2B purchasing behavior: account-centered, aware of buying groups, and trust-oriented. Our mission is to merge human discernment with automation, enabling sales teams to generate consistent, high-quality pipeline without compromising their brand integrity or their representatives' well-being.About the RoleWe are seeking a Principal Software Engineer to serve as a pivotal technical leader for Prospecting Solutions. This role is highly hands-on, perfect for an innovator who excels in dynamic, product-defining environments.As a Principal Engineer within our team, you will play a crucial role in shaping how data, AI, and workflows converge to facilitate intelligent prospecting at scale. You won't just follow a roadmap; you will help craft it, transforming ambiguous challenges such as “who should I contact next and with what message?” into robust, transparent, production-grade systems utilized by millions of sales professionals.Key ResponsibilitiesDesign signal-driven prospecting systems: Define the integration of intent signals, firmographics, behavioral insights, and CRM context to create actionable prioritization and recommendations.Hands-on, impactful developer: Write production-quality code, steer complex projects from conception to completion, and scale prototypes into full-fledged systems.AI and systems integration: Guide the integration of machine learning and generative AI models into deterministic workflows, balancing efficiency with transparency and user trust.Influential technical leadership: Shape not only the construction of the product but also its vision, collaborating closely with Product to define interfaces, workflows, and necessary trade-offs.Extensibility focus: Design systems capable of functioning across diverse accounts, buying groups, and regions while ensuring adaptability and ongoing evolution.Cross-department collaboration: Work collaboratively across CRM, data, AI, and GTM teams to synchronize patterns and avoid localized optimizations.Elevate technical standards: Foster a culture of excellence in engineering practices and innovation.

Join our dynamic team at Integrated Resources, Inc. as a Principal Application Administrator. In this pivotal role, you will oversee and manage our application systems, ensuring optimal performance and user satisfaction. You will collaborate with various departments to implement innovative solutions and enhance our technology infrastructure.

About Pioneering Intelligence Imagine harnessing the power of science, data, and artificial intelligence to revolutionize technology and accelerate innovation. This is the mission of Pioneering Intelligence, an initiative by Flagship Pioneering that aims to blend cutting-edge research with digital sciences. We are committed to creating AI and machine learning-driven platforms that can transform human health, sustainability, and more. Pioneering Intelligence builds upon Flagship's legacy of pioneering companies at the forefront of AI, driving advancements throughout the ecosystem and enabling the creation of groundbreaking innovations. Our team comprises computational scientists and engineers from diverse fields including applied mathematics, nuclear physics, engineering, and computational biology. We leverage our collective expertise to tap into the broad spectrum of scientific knowledge and promote innovative thinking that transcends conventional computational boundaries. We are constructing a next-generation digital foundation that combines computational science, AI/ML, knowledge engineering, data platforms, and workflow automation. These capabilities empower Flagship to explore uncharted territories and transform scientific insights into transformative enterprises. About the Role The Flagship Data Platform is a shared resource that facilitates swift progress for Flagship companies by providing secure and well-governed access to reliable data across our portfolio. As the Senior Director, Product Manager for the Data Platform, you will spearhead the product strategy, roadmap, and execution from initial use cases to widespread adoption. You will collaborate closely with software and ML engineers, UX designers, scientists, and senior stakeholders across various companies to convert ambiguous, high-value opportunities into impactful products that enhance scientific discovery and decision-making. You thrive in a dynamic, interdisciplinary environment and can seamlessly transition between strategic planning, discovery, and hands-on execution. Key Responsibilities Develop and maintain the comprehensive product vision and roadmap, establishing metrics and priorities to optimize impact. Swiftly conduct product discovery through user research, problem definition, prototyping, and validation. Coordinate priorities with an empowered technical lead. Utilize product analytics, qualitative feedback, and experimentation to guide decision-making. Effectively communicate results to stakeholders. Define and apply metrics to measure product effectiveness.

Your Impact at Lila As a Senior or Principal Research Engineer specializing in Synthetic Data, you will play a pivotal role in shaping the vision, roadmap, and execution of our synthetic data initiatives. Your responsibilities will span from asset generation and simulation to integrating machine learning training and achieving measurable enhancements in model performance. Collaborating closely with our Research Engineering team, you will design, generate, and implement artificial datasets aimed at training, testing, and refining Lila’s platform to achieve our strategic objectives. What You Will Build Define and refine the synthetic data strategy along with a comprehensive multi-quarter roadmap. Create evaluation frameworks that effectively connect synthetic interventions with genuine model performance. Establish high standards for asset quality, diversity, thorough documentation, and reproducibility while fostering a robust review culture. What You Will Need to Succeed Over 6 years of experience in applied ML/ML systems, with at least 3 years leading industry initiatives, showcasing a strong track record in advanced algorithms and frameworks designed for large-scale synthetic data generation. More than 8 years of experience working with contemporary ML workflows, including Python, PyTorch, dataset tools, training loops, and evaluation frameworks; adept at profiling and optimizing GPU-intensive pipelines. Bonus Points For A proven history of constructing synthetic datasets from source data to significantly enhance model performance in specific domains. Experience with instruction fine-tuning and hill-climbing techniques. Ability to translate product requirements and feedback into a scalable synthetic data generation pipeline. Knowledge of quantization, distillation, routing, mixture-of-experts, and cost optimization at scale. Experience in compliance-heavy settings (HIPAA, PCI, FedRAMP) and with on-premises/VPC deployments. About Lila Lila Sciences stands at the forefront of innovation as the world’s first scientific superintelligence platform and autonomous lab, dedicated to life sciences, chemistry, and materials science. We are ushering in an era of limitless discovery by harnessing AI to enhance every facet of the scientific method. Our mission is to empower scientists to tackle humanity's most pressing challenges in health, climate, and sustainability at an unprecedented pace and scale. Discover more about our mission at www.lila.ai. If this sounds like an environment in which you would thrive, we encourage you to apply even if your experience doesn't perfectly align with every requirement listed.

Are you ready to make a significant impact on the environment by joining a team of skilled ecologists? We invite you to become a vital member of our innovative Nature team as a Principal Ecologist in our expanding offices located in Cambridge, Basingstoke, Croydon, Leeds, Nottingham, Newcastle, Manchester, Birmingham, Glasgow, Edinburgh, Bristol, and Liverpool (other locations may also be considered). Enjoy the benefits of our flexible hybrid working model at AECOM, where we lead the way in delivering an exceptional portfolio of Ecology programs and projects through long-standing partnerships with key clients.We are currently engaged in a diverse array of projects across the power, renewables, infrastructure, environment, and transport sectors. Our collaborative efforts extend to other technical disciplines, including landscape, GIS, engineering, sustainability, and drainage. Recent projects include some of the largest solar farms in the UK, a cable tunnel beneath the River Thames, electricity network upgrades in Kent and Suffolk, and master planning for new residential developments.Your Responsibilities:Lead and support the delivery of high-quality ecological consultancy and advisory services to both internal and external clients.Oversee, plan, schedule, and organize all phases of ecological project work, ensuring that necessary resources, budgets, and controls are in place to meet program and budget requirements.Develop technically robust and pragmatic solutions to complex ecological challenges.Lead the production of ecology chapters for environmental statements and protected species license applications and ensure the high quality of project deliverables.Contribute to the ongoing development of our technical capabilities.Join Us in Our Growth Journey. Become part of our dynamic Nature business, which comprises around 230 professionals specializing in arboriculture, forestry, groundwater, surface water, and ecology. Our team includes national and global leaders in species licensing, impact assessment, habitat creation, ecosystem restoration, enhancement, and management. At AECOM, you will flourish in an inclusive and forward-thinking environment where your contributions are valued.Don't forget the amazing perks at AECOM! You will enjoy a variety of core and personalized benefits tailored to support your future and well-being, including career development opportunities, a flexible hybrid working model to enhance your work-life balance, technical practice networks, and access to AECOM University.

Teamwork makes the stream work. Join Roku, a Pioneer in TV StreamingAs the leading TV streaming platform in the U.S., Canada, and Mexico, Roku is revolutionizing how the world consumes television. Our mission is simple yet ambitious: to empower every television worldwide with our innovative streaming technology. By connecting viewers to their favorite content, enabling publishers to reach large audiences, and offering advertisers unique engagement tools, we are transforming the entertainment landscape.At Roku, we value every contribution. From your first day, you will play a crucial role in our mission to delight millions of streamers globally while gaining invaluable experience across various disciplines. About the Team As a Product Management Intern in the Live TV team within the Viewer Product organization, you will not merely observe; you will actively contribute to defining product requirements and the strategic rationale behind them. Utilizing big data and user research, you will delve into customer needs and business objectives. Your success will be measured by outcomes rather than mere outputs. We offer a paid 12-week internship starting in Summer 2026. About the Role In this role, you will be entrusted with a specific feature or product initiative, guiding a project from initial concept through to final delivery, employing industry-standard methodologies. You will play a key role in determining the "What" and "Why" of our offerings.

As a Principal Terrestrial Ecologist at dev2, you will play a pivotal role in leading and managing ecological projects that contribute to sustainable environmental practices. You will be responsible for conducting extensive field studies, analyzing ecological data, and providing expert guidance on terrestrial ecosystems. Your insights will help shape strategies that promote biodiversity and conservation.

Join our dynamic team at Ramboll as a Senior / Principal Electrical Engineer. In this role, you will lead innovative projects, collaborate with a talented team, and contribute to the development of sustainable electrical solutions. Your expertise will be pivotal in driving forward our commitment to excellence in engineering.