Senior Machine Learning Engineer at Roku | Cambridge, UK

Location: Cambridge, MA (Eastern Time / UTC -4). Relocation support is available. Remote work may be considered for candidates based outside Massachusetts.Start date: ASAPLanguages: English (required) Pragmatike is an AI startup founded by MIT CSAIL researchers, recognized by GTM Capital as a Top 10 GenAI company. The team develops advanced AI systems with a focus on real-world applications. Role overview The Principal Machine Learning Operations Engineer shapes the architecture and scaling of Pragmatike’s machine learning infrastructure. This senior position leads the design, implementation, and optimization of production AI systems, overseeing the full lifecycle from model training and evaluation to deployment, monitoring, and ongoing improvement. Collaboration is central in this role. The Principal ML Ops Engineer works closely with AI researchers, GPU systems engineers, backend developers, and product teams. The main focus is building reliable, efficient, and automated ML platforms to support large-scale AI deployments. Key responsibilities Architect, build, and improve the end-to-end ML Ops pipeline, including training, fine-tuning, evaluation, rollout, and monitoring. Design and maintain infrastructure for model deployment, version control, reproducibility, and orchestration across both cloud and on-premises GPU clusters. Optimize distributed systems for computational efficiency, covering Kubernetes, autoscaling, caching, GPU allocation, and checkpointing workflows. Establish observability for ML systems by monitoring model drift, performance, throughput, reliability, and operational costs. Automate workflows for dataset curation, labeling, feature engineering, evaluation, and CI/CD for ML models. Collaborate with researchers to bring models into production and improve training and inference pipelines. Set internal ML Ops standards, best practices, and develop tools that support cross-team collaboration. Mentor engineers and provide architectural guidance across the AI platform. Requirements Extensive hands-on experience designing and operating production ML systems at scale, ideally at the Staff or Principal level. Deep knowledge of ML Ops, distributed systems, and cloud infrastructure.

ABOUT PIONEERING INTELLIGENCE Pioneering Intelligence is a forward-thinking initiative that builds upon Flagship Pioneering's rich history of establishing groundbreaking scientific and computational enterprises. By leveraging cutting-edge advancements in artificial intelligence, machine learning, and data science, we aim to accelerate fundamental research and cultivate a dynamic portfolio of AI-first companies. As an integral part of Flagship's unique model that intertwines science, entrepreneurship, and investment, we transform revolutionary concepts into impactful companies, enhancing AI innovations that contribute to human health, sustainability, and more. THE ROLE We are on the lookout for a Principal Scientist specializing in Embedded Machine Learning and Computational Methods to spearhead various AI/ML and computational initiatives across early-stage ventures within our company origination framework. Your responsibilities will include defining and executing practical AI strategies, overseeing the development of methodologies and platforms (including systems design, drug design, molecular modeling, systems biology, protein design, and LLM-based workflows), and ensuring a high standard of rigor in model development, benchmarking, scaling, and reporting. You will also manage cross-functional teams as necessary, influence the strategic direction of our initiatives, and represent Pioneering Intelligence to venture teams and external collaborators. The ideal candidate is a self-motivated individual with a diverse skill set, capable of transitioning seamlessly from protein design to mass spectrometry or docking pipelines, and then creating LLM-based agents to streamline scientific workflows.

ABOUT PIONEERING INTELLIGENCEPioneering Intelligence extends Flagship Pioneering's tradition of launching innovative scientific and computational initiatives. By leveraging the latest advancements in AI, machine learning, and data analytics, we aim to expedite fundamental research and build a diverse portfolio of AI-first companies. As a key player in Flagship's integrated approach to science, entrepreneurship, and investment, we transform groundbreaking concepts into transformative enterprises that enhance AI innovations in human health, sustainability, and more.THE ROLEWe are on the lookout for a Principal Scientist specializing in Embedded Machine Learning and Computational Techniques to spearhead various AI/ML and computational initiatives across early-stage ventures in our company origination process. You will be responsible for defining and executing practical AI strategies, overseeing the development of methodologies and platforms such as systems design, drug design, molecular modeling, systems biology, protein design, and LLM-driven workflows while ensuring the utmost rigor in model development, benchmarking, scaling, and reporting. You will manage cross-functional contributors as necessary, influence the strategic direction of the company, and represent Pioneering Intelligence to venture teams and external partners. The ideal candidate is a proactive, deep thinker who can seamlessly transition between protein design one week and mass spectrometry or docking pipelines the next, while also developing LLM-based agents to automate scientific workflows.

ABOUT PIONEERING INTELLIGENCE Pioneering Intelligence continues the legacy of Flagship Pioneering by creating innovative scientific and computational ventures. Utilizing advancements in AI, machine learning, and data analytics, our mission is to expedite fundamental research and establish a diverse portfolio of AI-first companies. We integrate science, entrepreneurship, and capital to transform groundbreaking concepts into impactful companies, furthering AI advancements in human health, sustainability, and more. THE ROLE We are on the lookout for a Principal Scientist in Embedded Machine Learning/Computational to spearhead multiple AI/ML and computational projects within early-stage ventures as part of Flagship’s origination process. Your responsibilities will include defining and executing effective AI strategies, leading method and platform advancements (such as systems design, drug design, molecular modeling, systems biology, protein design, and LLM/agentic workflows), and ensuring excellence in model development, benchmarking, scaling, and reporting. You'll collaborate with cross-functional teams, shape the direction of the company, and represent Pioneering Intelligence to both venture teams and external partners. The ideal candidate is a proactive deep diver, capable of transitioning from protein design to mass spectrometry or docking pipelines, and then developing LLM-based agents to streamline scientific workflows.

Join Cambridge Mobile Telematics (CMT), the largest telematics service provider globally, dedicated to enhancing road safety and improving driver behavior. Our AI-driven platform, DriveWell Fusion®, integrates sensor data from numerous IoT devices, including smartphones, connected vehicles, and dashcams, to provide actionable insights for auto insurers, automakers, and public safety organizations. With headquarters in Cambridge, MA, and offices across the globe, we are committed to making a difference for millions of drivers every day.As a Principal Machine Learning Engineer on the innovative DriveWell Atlas team, you will lead the charge in developing cutting-edge AI systems leveraging telematics data. You will spearhead projects that involve the design, pre-training, fine-tuning, and deployment of novel foundation models aimed at revolutionizing risk assessment, driver engagement, and claims processing. This role demands a profound understanding of contemporary AI methodologies, machine learning, and sensor data analysis, offering the chance to construct a pioneering large language model from petabyte-scale datasets.We seek a collaborative and inventive Principal Machine Learning Engineer who is driven by a passion for making roads safer and improving driver capabilities.

Join Cambridge Mobile Telematics (CMT), the largest telematics service provider globally, dedicated to enhancing road safety for all drivers. Our innovative AI-driven platform, DriveWell Fusion®, aggregates data from millions of IoT devices—including smartphones, proprietary Tags, connected vehicles, and dashcams—fusing it with contextual information to provide a comprehensive view of driver and vehicle behavior. Our insights are utilized by auto insurers, automobile manufacturers, commercial mobility companies, and public sector entities to enhance risk assessment, safety protocols, claims processing, and driver improvement initiatives. With our headquarters in Cambridge, MA, and offices in Budapest, Chennai, Seattle, Tokyo, and Zagreb, we safeguard millions of drivers worldwide every day.As a Principal Machine Learning Engineer at CMT, you will craft algorithms that model the physical phenomena associated with vehicle and human movements as captured by mobile sensors and IoT devices. Your expertise will help solve complex real-world challenges and drive innovative solutions through exploratory data analysis on intricate, high-dimensional datasets. Leveraging your knowledge in statistics, machine learning, deep learning, signal processing, physics, programming, and data modeling, you will spearhead Data Science projects, independently create new solutions to meet CMT’s goals, and contribute to company-wide prototype development and product enhancements.If you are a collaborative, customer-focused, and inventive Principal Machine Learning Engineer eager to contribute to safer roads and better driving practices, we welcome your application!

Join the Team at GraphcoreAt Graphcore, we are at the forefront of revolutionizing AI computation. Our team of experts in semiconductors, software, and artificial intelligence is committed to developing an advanced AI compute stack that encompasses everything from silicon to datacenter infrastructure.As a proud member of the SoftBank Group, we are supported by significant long-term investment, enabling us to drive crucial technology within the rapidly expanding SoftBank AI ecosystem.To address the immense opportunities within the AI landscape, we are seeking to expand our teams globally. We welcome the brightest minds to tackle the most challenging problems, ensuring that every team member has an opportunity to influence our company, our products, and the future of AI.

Your Impact at Lila As a Machine Learning Engineer on the Physical Sciences team, you will play a pivotal role in developing and managing comprehensive, scalable machine learning workflows. These workflows will address a wide range of scientific challenges in materials science, chemistry, and physical sciences. Your contributions will be instrumental in advancing research initiatives focused on cutting-edge algorithms, driving towards the establishment of scientific superintelligence to tackle today’s most significant challenges in physical sciences. What You Will Build Design, implement, and sustain end-to-end ML pipelines, encompassing data ingestion, feature engineering, model training, evaluation, deployment, and monitoring. Productionize models and services while ensuring robust testing, observability, and documentation in collaboration with cross-functional software teams; develop CI/CD workflows and automated evaluations to facilitate safe and frequent releases. Work closely with domain scientists and platform engineers to translate research insights into high-performing, scalable systems. Participate in technical design reviews, establish coding standards, and mentor colleagues on best practices. What You’ll Need to Succeed BS, MS, or PhD in Computer Science, Engineering, or a related quantitative field, or equivalent industry experience. A solid foundation in Python software engineering, including testing, packaging, and typing; experience with machine learning frameworks such as PyTorch and Hugging Face. Experience deploying ML services in cloud-based environments (FastAPI/GRPC, containers, orchestration, cloud infrastructure). Hands-on experience with deploying models in production systems (LLMs, multimodal models, databases, RAG) along with strong debugging and profiling skills. Effective communication and collaboration in cross-functional settings. Bonus Points For Familiarity with scientific or engineering domains (materials, chemistry, physics) and related data formats/benchmarks. Experience in GPU optimization (CUDA, Triton, compilation, distributed training). Previous contributions to open-source ML or scientific software. Experience with workflow orchestration, data provenance, or large-scale computing environments. About Lila Lila Sciences stands as the pioneering platform for scientific superintelligence, offering an autonomous laboratory dedicated to life sciences, chemistry, and materials science. We are at the forefront of a new era of limitless discovery, harnessing AI to revolutionize research and innovation in these fields.

Collaboration Drives Innovation. Join Roku in Transforming Television ViewingRoku stands as the premier TV streaming platform across the U.S., Canada, and Mexico, aiming to revolutionize how people experience television on a global scale. As pioneers in TV streaming, our mission is to create a platform that connects the entire television ecosystem. We bridge the gap between consumers and their favorite content, empower content creators to reach and monetize vast audiences, and equip advertisers with unique tools to engage effectively with viewers.At Roku, your contributions are vital from day one. As a rapidly expanding public company, we value proactive engagement from all employees. This is your chance to create delightful experiences for millions of TV streamers worldwide while gaining invaluable experience across diverse disciplines. About the TeamWith over 70 million active accounts, Roku leads the way in the TV streaming industry across North America. Our commitment to machine learning and innovative recommendation systems is central to our ongoing success. We enable users to access an extensive library of content, including movies, series, news, sports, music, and channels from around the globe. Role OverviewIn this role, you will deepen our understanding of queries, content, and user behavior through machine learning. Your work will be pivotal in enhancing user satisfaction throughout their search journey. Tackling these challenges is at the heart of our mission to improve customer experience.

Collaboration Fuels Innovation. Join Roku - Revolutionizing TV ViewingAs the leading TV streaming platform in the U.S., Canada, and Mexico, Roku is on a mission to empower every television worldwide. Pioneering the streaming experience, we connect viewers to their favorite content, support publishers in audience growth and monetization, and provide advertisers with exceptional tools for consumer engagement.From day one at Roku, your contributions will be valued. We are a rapidly expanding public company where every team member plays an essential role. This is your chance to impact millions of TV streamers globally while gaining significant experience across diverse disciplines. About Our TeamThe Advertising Performance team is dedicated to optimizing the performance of all participants in the advertising ecosystem, including advertisers, publishers, and Roku itself. Our systems and solutions leverage various disciplines and technologies for real-time, multi-objective optimization on a large scale with minimal latency. Utilizing Machine Learning, Reinforcement Learning, AI, and Optimization Systems, we tackle a wide array of complex challenges. Central to our efforts is our Machine Learning, Experimentation, and Inference Platform that supports the entire operational landscape.

Join Cambridge Mobile Telematics (CMT), the leading provider of telematics solutions worldwide, dedicated to enhancing road safety for drivers everywhere. Our innovative AI-driven platform, DriveWell Fusion®, aggregates sensor information from millions of IoT devices—including smartphones, connected vehicles, dashcams, and proprietary Tags—along with contextual data to deliver an integrated perspective on vehicle and driver behavior. Our insights empower auto insurers, automakers, commercial mobility firms, and government entities to enhance risk assessment, safety protocols, claims management, and driver improvement initiatives. With headquarters in Cambridge, MA and additional offices in Budapest, Chennai, Seattle, Tokyo, and Zagreb, we protect and monitor millions of drivers globally every day.CMT is seeking a talented and experienced Senior Software Engineer to contribute to the development and scalability of our on-device Machine Learning systems within the Mobile SDK. This pivotal team is responsible for the core C/C++ runtime that enables real-time sensor data processing and machine learning across a multitude of mobile devices. Our platform facilitates swift updates and deployment of driving behavior algorithms while ensuring optimal performance, battery efficiency, and operational accuracy.If you are a collaborative, customer-focused, and innovative individual eager to help us improve road safety by enhancing driver behavior, we invite you to apply!

About Graphcore At Graphcore, we are pioneering the future of AI computation. Our team consists of semiconductor, software, and AI specialists with extensive experience in creating a complete AI compute stack—from silicon and software to infrastructure at datacenter scale. As a proud member of the SoftBank Group, we are supported by significant long-term investments, allowing us to deliver vital technology to the rapidly expanding SoftBank AI ecosystem. To seize the immense and exciting opportunities in AI, Graphcore is actively expanding its teams globally, uniting the brightest minds to tackle the most challenging problems in an environment where everyone can significantly impact the company, its products, and the future of artificial intelligence. Job Summary In the role of Senior Machine Learning Engineer within the Applied AI team at Graphcore, you will play a crucial part in advancing AI technology by developing and optimizing AI models specifically designed for our specialized hardware. You will engage with large-scale systems where performance is paramount to the success of our initiatives. Collaborating closely with both the Software Development and Research teams, you will be instrumental in identifying innovative opportunities that set Graphcore’s technology apart. We are looking for engineers with robust technical skills and a deep understanding of large-scale AI model implementation, eager to make a meaningful impact in this fast-evolving field. The Team The Applied AI team's mission is to serve as advocates for our customers. We continually strive to understand the latest AI models, applications, and software to ensure that Graphcore’s technology integrates seamlessly with the AI ecosystem and operates efficiently at scale. Our responsibilities include building reference applications, optimizing key software libraries (including kernel efficiency on our hardware), and collaborating with the Research team to develop and publish innovative ideas across domains such as efficient computation, model scaling, and distributed training and inference of AI models across various modalities and applications. If you are passionate about advancing the next generation of AI models on cutting-edge hardware, we would love to hear from you!

Are you passionate about advancing the field of machine learning? Join our team at Altos Labs as a Machine Learning Scientist or Senior Machine Learning Scientist. In this role, you will leverage your expertise to drive innovation and development in cutting-edge research projects. Collaborate with a multidisciplinary team to push the boundaries of machine learning technology.

Your Role at Lila Sciences We are seeking a talented Senior Software Engineer to collaborate with our Machine Learning Engineers and Researchers. You will be instrumental in developing software that enhances Lila’s ML workflows and research tools. Join a dynamic team of engineers as you contribute to the development, support, and maintenance of Lila’s cutting-edge ML libraries and tools. Your Contributions Create and optimize high-performance, secure, and thoroughly documented Machine Learning libraries that implement algorithms crafted by our machine learning specialists. Develop CI/CD pipelines and integration tests to streamline ML workflows. Design repository architectures that adhere to consistent standards. Assist with debugging, logging, and ongoing maintenance of Ray-based compute environments. Establish data ingestion pipelines connecting lab data with the ML teams. Qualifications for Success A minimum of 8 years of software development experience in commercial environments using Go or Python. Proven track record in implementing scalable software solutions. Familiarity with MLOps systems and GitOps tools (ArgoCD, GitHub Actions). Experience with orchestration frameworks like Ray, Argo, or Airflow. Strong knowledge in containerization, Kubernetes, and infrastructure-as-code tools. Excellent listening skills and the ability to comprehend complex problems and algorithms. Outstanding problem-solving abilities and a collaborative mindset. Self-motivated and detail-oriented, eager to work with dynamic, skilled teams in a fast-paced, entrepreneurial environment. Preferred Qualifications Experience with monitoring and logging tools such as Prometheus and Grafana. Background in research engineering or scientific software development. About Lila Sciences Lila Sciences is at the forefront of scientific innovation, pioneering the world’s first scientific superintelligence platform and autonomous laboratory for life sciences, chemistry, and materials science. We are committed to transforming the landscape of discovery by applying AI to every facet of the scientific method. Our mission is to leverage scientific superintelligence to address humanity's most pressing challenges, empowering scientists to deliver solutions in health, climate, and sustainability with unprecedented speed and scale. Discover more about our vision at www.lila.ai.

Your Impact at Lila As a Senior or Principal Research Engineer specializing in Synthetic Data, you will play a pivotal role in shaping the vision, roadmap, and execution of our synthetic data initiatives. Your responsibilities will span from asset generation and simulation to integrating machine learning training and achieving measurable enhancements in model performance. Collaborating closely with our Research Engineering team, you will design, generate, and implement artificial datasets aimed at training, testing, and refining Lila’s platform to achieve our strategic objectives. What You Will Build Define and refine the synthetic data strategy along with a comprehensive multi-quarter roadmap. Create evaluation frameworks that effectively connect synthetic interventions with genuine model performance. Establish high standards for asset quality, diversity, thorough documentation, and reproducibility while fostering a robust review culture. What You Will Need to Succeed Over 6 years of experience in applied ML/ML systems, with at least 3 years leading industry initiatives, showcasing a strong track record in advanced algorithms and frameworks designed for large-scale synthetic data generation. More than 8 years of experience working with contemporary ML workflows, including Python, PyTorch, dataset tools, training loops, and evaluation frameworks; adept at profiling and optimizing GPU-intensive pipelines. Bonus Points For A proven history of constructing synthetic datasets from source data to significantly enhance model performance in specific domains. Experience with instruction fine-tuning and hill-climbing techniques. Ability to translate product requirements and feedback into a scalable synthetic data generation pipeline. Knowledge of quantization, distillation, routing, mixture-of-experts, and cost optimization at scale. Experience in compliance-heavy settings (HIPAA, PCI, FedRAMP) and with on-premises/VPC deployments. About Lila Lila Sciences stands at the forefront of innovation as the world’s first scientific superintelligence platform and autonomous lab, dedicated to life sciences, chemistry, and materials science. We are ushering in an era of limitless discovery by harnessing AI to enhance every facet of the scientific method. Our mission is to empower scientists to tackle humanity's most pressing challenges in health, climate, and sustainability at an unprecedented pace and scale. Discover more about our mission at www.lila.ai. If this sounds like an environment in which you would thrive, we encourage you to apply even if your experience doesn't perfectly align with every requirement listed.

Our MissionAt Altos Labs, our mission is to rejuvenate cell health and resilience, aiming to reverse diseases, injuries, and the associated disabilities that arise throughout life.For further details, visit our website at altoslabs.com.Our ValuesWe embrace a singular value at Altos: Everyone Owns Achieving Our Inspiring Mission.Diversity at AltosWe hold a firm belief that diverse perspectives are crucial to scientific advancement and inquiry. At Altos, outstanding scientists and industry leaders collaborate from across the globe to further our shared mission. We prioritize creating a sense of belonging, ensuring that every employee feels valued for their unique contributions. We are collectively responsible for maintaining a diverse and inclusive workplace.Your Contributions to AltosIn the role of Senior or Principal Machine Learning Scientist, you will be instrumental in the development of generative AI/ML models for multi-modal, multiscale biology, spanning from virtual cells to agentic target assessment. We seek a hands-on, innovative, and collaborative individual to join our multidisciplinary team of scientists and engineers dedicated to transforming the treatment of aging and disease. The ideal candidate will flourish in a dynamic environment that values teamwork, transparency, scientific excellence, originality, rigor, and integrity.

Join Luminance, a pioneering AI firm in the UK that is transforming the legal sector. Recognized in Tech Nation’s Future Fifty list and awarded with two Queen’s Awards, Luminance stands at the forefront of advanced AI technology.We are seeking passionate and dedicated candidates with a robust academic background in Artificial Intelligence or a related discipline to enrich our R&D team in Cambridge. As a member of our agile team, you will be instrumental in prototyping, developing, and executing innovative solutions to complex AI challenges, while assessing output quality, efficiency, and feasibility in a data-driven environment.This position is open to recent graduates eager to learn and seasoned professionals with substantial experience in the field.If you’re enthusiastic about this opportunity but feel your skills or experience don’t fully match the job description, we encourage you to apply. At Luminance, we are committed to fostering an inclusive workplace where everyone can thrive. Your enthusiasm may be the key to our search for the right candidate, whether for this role or another!

Join Cambridge Mobile Telematics (CMT), the leading telematics service provider dedicated to enhancing road safety and driver behavior. Our innovative AI-powered platform, DriveWell Fusion®, integrates sensor data from millions of IoT devices—including smartphones, proprietary Tags, connected vehicles, and dashcams—to deliver a comprehensive analysis of driving patterns and vehicle dynamics. Our insights are leveraged by auto insurers, automakers, and mobility companies to improve risk assessment, safety measures, and claims processes.We are excited to announce the development of DriveWell Atlas, a cutting-edge suite of foundation models that utilizes large-scale, multi-modal telematics signals to promote safer driving outcomes across various workflows such as risk assessment, safety improvement, and claims management.As a key contributor to our IC2 Foundation Models team, you will collaborate with experienced scientists and engineers to prototype, train, evaluate, and deploy time-series foundation models. This highly technical role is ideal for individuals with a solid software background and emerging expertise in applied machine learning.

Your Impact at Lila Join our dynamic team in the Physical Sciences division as a Senior Machine Learning Engineer. In this pivotal role, you will be instrumental in shaping the infrastructure that empowers Lila’s scientific superintelligence to autonomously design, execute, and interpret intricate physics simulations. Your expertise will be critical in developing core systems that enable AI agents to reason over and control computational experiments, ranging from electronic structure calculations to surrogate-driven atomistic modeling, and beyond. Your contributions will directly enhance the capability of autonomous computational processes to explore chemical and materials landscapes with unmatched autonomy and robustness. What You Will Be Building Architect and implement agentic frameworks to support dynamic, multi-stage simulation workflows for scientific tasks. Develop pipelines that allow agents to autonomously plan, schedule, execute, and interpret computational tasks at scale. Create integration layers and APIs that connect machine learning models, large-scale simulation engines, databases, and heterogeneous compute platforms. Collaborate with AI researchers to productionize agent behaviors, including tool-use strategies, simulation-aware decision loops, and adaptive task planning. Enhance the robustness, modularity, performance, and reproducibility of agent-driven computational workflows; develop internal tooling for debugging, observability, and validation. What You’ll Need to Succeed A Master's degree or PhD in Computer Science, Machine Learning/AI, Scientific Computing, or a related technical field, or equivalent experience. Proven experience in building machine learning-driven pipelines, workflow systems, or tool-use frameworks, particularly for complex or scientific applications. Proficiency in Python and familiarity with machine learning ecosystems; experience with compiled languages such as C++, Rust, or Julia is advantageous. Understanding of large-scale scientific or engineering software, including integrating external tools into automated computational workflows. Background in distributed systems, high-performance computing environments, cloud platforms, or accelerator-based computing. A solid grasp of modern machine learning architectures and their deployment in production systems (e.g., GNNs, transformers, diffusion models, multimodal or tool-using models). Strong engineering fundamentals: reproducibility, testing, modular design, CI/CD, and scalable machine learning operations. Bonus Points For Experience developing or integrating agentic frameworks, autonomous machine learning pipelines, or multi-step tool-using agents, particularly for scientific applications.