Senior Clinical Scientist, Oncology

We are seeking a highly skilled Senior Scientist to join our Research and Development team at Natera in San Carlos, California. In this pivotal role, you will lead innovative projects that contribute to groundbreaking advancements in genetic testing and diagnostics. You will collaborate with cross-functional teams, driving research initiatives that enhance our product offerings and improve patient outcomes.

Role Overview Natera is hiring a Senior Manager of Research and Development for the Oncology Product Development team in San Carlos, CA. This leader will guide the development and optimization of next-generation sequencing (NGS)-based oncology diagnostic assays. The position also supports ongoing product lifecycle management after launch. Success in this role depends on strong technical leadership, cross-functional collaboration, and a focus on product performance and scalability. What You Will Do Direct the technical development of NGS-based oncology assays, including project planning, execution, and coordination across teams. Drive assay development from feasibility through verification and validation in a regulated CLIA setting. Work closely with Research, Informatics, Statistics, Software, Regulatory, Quality, and Commercial groups to move products from concept to launch. Support post-launch efforts such as process improvements, troubleshooting, and working with Operations on commercialized assays. Prepare and review technical documents, including study protocols, reports, and validation materials, ensuring regulatory and product requirements are met. Mentor and manage team members, supporting their professional growth. Lead and oversee data analysis using statistical methods. Qualifications PhD in Molecular Biology or related field with at least 6 years of relevant industry experience, or BS/MS with a minimum of 8 years in biotech, including at least 2 years in management. Hands-on experience developing NGS-based assays in a regulated environment (CLIA experience preferred). Familiarity with CLIA laboratory workflows and assay implementation in production. History of leading projects and collaborating across functions; people management experience is a plus. Experience with high-throughput workflows or automation is beneficial. Knowledge and Skills Deep technical knowledge of oncology diagnostics and NGS technologies. Strong analytical thinking and problem-solving skills. Skilled in technical writing and documentation for regulated environments. Understanding of regulatory standards and design control processes (such as LDT, CAP/CLIA, product development lifecycle, and change management). Excellent collaboration, communication, and interpersonal abilities.

Join our dynamic team at Artech Information Systems LLC as a Senior Research Associate. In this role, you will be responsible for conducting in-depth research, analyzing data trends, and presenting findings to drive strategic decision-making. You will collaborate with cross-functional teams to support ongoing projects and contribute to innovative solutions within the organization.

Join Our Mission to Safeguard Humanity!Vaxcyte is a pioneering clinical-stage company focused on developing high-fidelity vaccines aimed at protecting humanity from the devastating impacts of bacterial diseases. Our commitment extends to eradicating or managing bacterial infections, such as invasive pneumococcal disease, Group A Strep, and Shigella. With a clear and defined pathway to success, Vaxcyte is poised to make significant strides in public health. Our Approach: At Vaxcyte, we believe that what we do is as significant as how we do it. Our collaborative efforts are anchored in four core values: *RETHINK CONVENTION: We foster creativity and intellectual diversity in every aspect of our work to continuously innovate vaccine delivery. *AIM HIGH: We embrace our bold mission to develop the most complex biologics ever created for the betterment of humanity. *LEAD WITH HEART: Our inclusive and kind-first approach promotes collaboration and constructive discussions that drive our business objectives forward. *MODEL EXCELLENCE: The scale of our challenges necessitates a collective commitment to integrity, accountability, equality, and clarity in our communications and decisions.Position Overview:Vaxcyte is looking for a dynamic Director of Health Economics & Outcomes Research (HEOR) to spearhead the company’s health economic strategy throughout the vaccine lifecycle, with an initial emphasis on adult pneumococcal programs. This strategic leadership position will be integral in developing and implementing global health economic models that underpin payer value propositions, immunization policy engagement, reimbursement strategies, and communication with external stakeholders.This role will concentrate on health economic modeling and payer value strategy, collaborating closely with the Epidemiology and Real-World Evidence (RWE) teams to ensure that economic models are based on solid disease burden, vaccine effectiveness, and coverage assumptions.As Vaxcyte moves toward commercialization, this position will work in partnership with Market Access colleagues to shape pricing and contracting strategies, providing analytical support that aligns with the company's goals.

Join Natera as a Lead Biostatistician in Clinical Research, where you will play a pivotal role in the design and analysis of clinical trials. You will collaborate closely with cross-functional teams and contribute to the advancement of innovative healthcare solutions. This is an exciting opportunity to lead statistical programming efforts, ensuring the highest standards of quality and compliance in clinical data analysis.

Join Our Mission to Safeguard Humanity!Vaxcyte is at the forefront of vaccine innovation, dedicated to developing high-fidelity vaccines aimed at protecting humanity from serious bacterial diseases. Our commitment to eradicating or effectively treating infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. With a clear and well-defined path ahead, Vaxcyte is positioned for long-term success. Our approach is defined by our core values: *RETHINK CONVENTION: We embrace creative and intellectual diversity to innovate and continuously improve vaccine delivery. *AIM HIGH: We pursue our collective audacious goal of developing the most complex biologics to protect humanity. *LEAD WITH HEART: At Vaxcyte, we lead with kindness and inclusivity, fostering collaborative discussions that propel our business objectives. *MODEL EXCELLENCE: Our significant challenges demand a shared commitment to integrity, accountability, equality, and clear communication.Role Summary:The Senior Manager for Drug Substance (DS) Commercialization will oversee the launch readiness and commercial supply of the conjugate drug substance. This role will facilitate the transition of the conjugate product strategy from the Process Development team to Manufacturing Science and Technology (MSAT) during the late stages of product development. Key responsibilities include technical launch planning and execution, implementing best practices, and coordinating cross-functional efforts for regulatory submissions, facility preparations, and launch materials.The successful candidate will provide leadership to ensure effective communication of the scientific and commercial rationale for the conjugation process to internal stakeholders, relevant Contract Manufacturing Organizations (CMOs), and regulatory bodies. Exceptional written communication skills are essential, particularly in authoring submissions to Health Authorities (IND/BLA). The ability to collaborate with individuals from diverse backgrounds and perspectives is crucial for success in this role.

Join Our Mission to Safeguard Humanity!Vaxcyte is a pioneering clinical-stage vaccine innovation company dedicated to engineering high-fidelity vaccines aimed at protecting humankind from the dire consequences of bacterial diseases, which can lead to severe and costly health issues if not addressed. Our efforts to combat and potentially eliminate bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella are just the beginning of our journey towards success. Vaxcyte is strategically positioned to achieve its goals. Our Work Philosophy: We believe that what we do is as crucial as how we go about it! Our collaborative efforts are guided by four foundational core values: *RETHINK CONVENTION: We embrace intellectual diversity and creativity at every level to innovate and continuously improve vaccine delivery methods. *AIM HIGH: We strive to achieve our ambitious goal of creating the most complex biologics ever developed to protect humanity. *LEAD WITH HEART: Every team member at Vaxcyte approaches leadership with kindness and inclusivity, fostering collaboration and constructive debate to meet our business objectives. *MODEL EXCELLENCE: The scale of our mission demands a unified commitment to integrity, accountability, equality, and clear communication in all our decisions. Position Overview:Vaxcyte is seeking an enthusiastic and skilled Senior Engineer to join our Polysaccharide Development and Manufacturing team within the CMC group. The successful candidate will play a pivotal role in developing a multi-valent polysaccharide-based conjugate vaccine, utilizing a novel carrier protein produced via the Xpress CF platform. With a strong emphasis on downstream purification for early-stage development and late-stage process characterization, the ideal candidate should possess significant experience in these areas. Familiarity with Design of Experiments (DOE) methodologies and proficiency in statistical software (e.g., JMP) are essential. Proven leadership in project initiatives and team management is required. The candidate must be eager to acquire new lab skills, as they will collaborate on experimental designs and execute experiments to advance our polysaccharide development and manufacturing initiatives. This role entails over 50% laboratory time, and the candidate should be capable of working independently and in collaboration with cross-functional teams.

Natera is hiring a Research Scientist to join the R&D team in San Carlos, CA. This role centers on developing new technologies and methods that support patient care. Key responsibilities Design and execute experiments aligned with research objectives Analyze data from experiments and interpret findings Collaborate with colleagues across various disciplines to move research projects forward Role overview This position offers the chance to contribute to technology and method development within a collaborative research environment. The focus remains on work that can positively impact patient care through scientific innovation.

About Vaxcyte Vaxcyte, Inc. is advancing vaccine research in San Carlos, California, with a focus on high-fidelity vaccines targeting serious bacterial diseases. The team works to address infections such as invasive pneumococcal disease, Group A Streptococcus, and Shigella. Vaxcyte’s mission centers on reducing or managing these health threats through innovative science and a clear, strategic vision. Our Values Rethink Convention: Encourage creativity and welcome diverse perspectives to improve vaccine delivery. Aim High: Pursue ambitious goals in developing complex biologics for public health. Lead with Heart: Foster a collaborative culture rooted in kindness, inclusivity, and healthy debate. Model Excellence: Commit to integrity, accountability, and clear communication in all work. Role Overview: Associate Scientist II, Vaccine Research The Research team relies on a broad set of chromatographic techniques to purify vaccine antigens. This role calls for hands-on experience with multiple chromatography methods, including monoclonal antibody/Protein A workflows. Candidates should have worked on selecting, screening, developing, scaling up, and characterizing various chromatography techniques. Main Responsibilities Carry out AKTA FPLC chromatography, including: Immobilized metal affinity chromatography (IMAC) Ion-exchange chromatography (IEX) Hydrophobic interaction chromatography (HIC) Size-exclusion chromatography (SEC) Hydroxyapatite (CHT / HA) Design chromatography trains to reduce host cell proteins, endotoxins, and aggregates by combining complementary techniques. Apply Design of Experiments (DoE) for multimodal optimization (experience in this area is a plus). Use membrane chromatography for high-throughput contaminant analysis.

Role Overview Natera is seeking a Senior Scientist focused on In Vitro Diagnostic (IVD) Product Development in San Carlos, CA. This position leads key projects that influence the direction of diagnostic technology and support advancements in patient care. What You Will Do Lead IVD product development initiatives from concept through implementation. Collaborate closely with cross-functional teams to refine development processes. Ensure all work aligns with applicable regulatory standards. Collaboration and Impact This role works across multiple disciplines to strengthen Natera’s product pipeline and uphold quality in every stage of development.

Join Our Mission to Protect Humanity!Vaxcyte is a pioneering clinical-stage vaccine development company dedicated to engineering high-fidelity vaccines aimed at safeguarding humanity from the dire impacts of bacterial diseases. Our goal is to eradicate or effectively manage bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella. With a clear and well-defined path to success, Vaxcyte is positioned to achieve remarkable advancements in public health. Our Approach: What we do is just as important as how we do it! Our collaborative efforts are driven by four enduring core values: *RETHINK CONVENTION: We embrace creative and intellectual diversity in our work, innovating and re-innovating the delivery of vaccines. *AIM HIGH: We embody our audacious goal of courageously developing the most complex biologics ever created to protect humanity. *LEAD WITH HEART: Every team member at Vaxcyte leads with a kindness-first, inclusive approach, fostering collaboration and robust discussion that propels our business forward. *MODEL EXCELLENCE: The scale of our challenge necessitates a shared commitment to integrity, accountability, equality, and clarity in communication and decision-making.Position Summary:Vaxcyte is currently seeking a Senior Associate Scientist (Contract) specializing in Conjugation Development. This role will support the development of a robust process for generating our proprietary pneumococcal conjugate vaccine. Responsibilities include reviewing analytical data and electronic notebook entries for accuracy and compliance with standard operating procedures (SOPs). This is a remote, part-time position offering flexible working hours, requiring exceptional organizational skills, clear communication, and meticulous attention to detail.

Join Our Mission to Safeguard Humanity!Vaxcyte is a pioneering clinical-stage vaccine development company dedicated to creating high-fidelity vaccines aimed at safeguarding humanity from the dire consequences of bacterial diseases. Our mission is not just to combat but to eradicate or effectively treat serious bacterial infections including invasive pneumococcal disease, Group A Strep, and Shigella. We have a clear, structured path to success, and Vaxcyte is prepared to lead the charge. Our Approach: Our work is defined by our commitment to four core values: *Challenge the Norm: We infuse creativity and diverse perspectives into all aspects of our endeavors to revolutionize vaccine delivery. *Aim High: We strive to achieve our ambitious goal of developing the most complex biologics ever created to protect humanity. *Lead with Empathy: Every team member at Vaxcyte fosters a collaborative environment that prioritizes kindness and constructive debate, propelling our objectives forward. *Exemplify Excellence: The challenges we face demand a collective commitment to integrity, accountability, and transparent communication.Position Overview:We are on the lookout for a highly motivated and detail-oriented Senior Associate Scientist (Contract) to join our Polysaccharide Analytical Development team. The primary focus of this role is to support the analytical testing and characterization of polysaccharide-based drug candidates. The successful candidate will execute and refine various biochemical and chromatographic assays, contribute to method development initiatives, and ensure the generation of high-quality data in alignment with our research and development programs.This position demands robust hands-on experience with HPLC-based techniques, biochemical assays, and analytical software platforms, alongside a steadfast commitment to data integrity, meticulous documentation, and collaborative efforts across functions.

About Vaxcyte Vaxcyte is a clinical-stage vaccine company based in San Carlos, California. The team focuses on developing vaccines that help prevent serious bacterial diseases, including invasive pneumococcal disease, Group A Strep, and Shigella. The company’s mission centers on advancing vaccine science to protect communities worldwide. Our Values Rethink Convention: Encouraging new ideas and diverse viewpoints to improve vaccine delivery. Aim High: Pursuing major advancements in biologics to promote better health outcomes. Lead with Heart: Practicing kindness, inclusivity, and open communication in leadership and teamwork. Model Excellence: Upholding integrity, accountability, equality, and clear communication in every challenge. Role Overview: Senior Manager of Indirect Procurement for Clinical Development The Senior Manager of Indirect Procurement for Clinical Development will lead procurement activities that support clinical development programs at Vaxcyte. This position acts as a strategic partner to the Clinical Operations Department and works closely with Finance and Legal teams. The role covers the full procurement process for clinical trials, from project start to closeout, and adapts to changing indirect spend categories across the company. Key Responsibilities Manage procurement support for clinical development initiatives. Oversee the requisition to purchase order process for clinical trials. Support vendor selection and coordinate contracts to ensure timely, compliant, and cost-effective engagements. Collaborate with Clinical Operations, Finance, and Legal teams throughout the procurement lifecycle.

Join Our Mission to Safeguard Humanity!At Vaxcyte, we are pioneering vaccine innovation to safeguard humankind against the severe health impacts of bacterial diseases. Our efforts aim to eradicate or treat infections such as invasive pneumococcal disease, Group A Strep, and Shigella. With a clear and structured path to success, Vaxcyte is poised to make a profound impact in the realm of healthcare. Our Approach: We believe that the manner in which we achieve our goals is as critical as the goals themselves. Our collaborative efforts are anchored by four foundational values: *Rethink Convention: We embrace creativity and diverse perspectives to innovate and continuously improve vaccine delivery methods. *Aim High: We strive to achieve audacious goals, tackling the most complex biologics to protect humanity. *Lead with Heart: Leadership at Vaxcyte is characterized by kindness, inclusivity, and constructive debate to further our business objectives. *Model Excellence: We are committed to integrity, accountability, and clarity in all communications and decision-making processes.Position Summary:The Development organization consists of four specialized Process teams: Protein, Polysaccharide, Conjugate Drug Substance (Conjugation), and Drug Product, supported by Analytical Development and Formulation Development teams. Vaxcyte is seeking a Senior Associate Scientist (contract) with expertise in microbial fermentation and upstream processing to join our Upstream Polysaccharide Process Development team. The successful candidate will lead experimental design and execution to enhance and optimize polysaccharide manufacturing processes involving microorganisms. A hands-on laboratory background in microbial fermentation is essential, along with a keen willingness to acquire new laboratory skills. This role mandates over 50% of time spent in the lab, requiring the ability to independently document experimental procedures and results in both written and presentation formats. Additionally, the candidate will work closely with cross-functional teams, drafting technical reports and presenting experimental findings.

Join Our Mission to Protect Humankind!Vaxcyte is a pioneering clinical-stage vaccine innovation company dedicated to engineering high-fidelity vaccines aimed at safeguarding humanity from the devastating impacts of bacterial diseases. Our mission focuses on eradicating or effectively treating bacterial infections such as invasive pneumococcal disease, Group A Streptococcus, and Shigella. We are committed to a clear and defined path to success, ensuring Vaxcyte is prepared for the long haul. Our Approach: The impact of our work is equally as significant as the methodology we employ! Our collaborative efforts are driven by four fundamental core values: *RETHINK CONVENTION: We cultivate creative and intellectual diversity in all our endeavors to continuously innovate vaccine delivery methods. *AIM HIGH: We collectively strive to achieve audacious goals, tackling the most complex biologics for humanity's protection. *LEAD WITH HEART: At Vaxcyte, everyone contributes with a kindness-first, inclusive ethos that promotes collaboration and constructive debate, advancing our organizational objectives. *MODEL EXCELLENCE: The scale of our challenges demands a shared commitment to integrity, accountability, equality, and clarity in communication and decision-making.Position Summary:Vaxcyte is in search of an Associate Scientist II (contract) to bolster our research and development efforts for a groundbreaking bacterial polysaccharide conjugate vaccine. This role will play a crucial part in the setup, synthesis, purification, and analytical characterization of chemically modified polysaccharides and polysaccharide-protein conjugates.The ideal candidate should possess a robust understanding of conjugation process development, analytical chemistry principles, and significant hands-on laboratory experience. The successful individual will be expected to independently optimize and troubleshoot upstream and downstream conjugation processing procedures with minimal supervision. Contributions will extend to various related areas, including analytical development, stability studies, and process optimization initiatives. Responsibilities will also encompass record management, data presentation at team meetings, and collaborative authorship of laboratory protocols and development reports.

Role Overview Vaxcyte is hiring a Senior Manager, Supply Chain Planning in San Carlos, California. This leader will guide a team responsible for demand planning, inventory management, and supplier coordination. The work supports smooth production and distribution of Vaxcyte’s vaccine products.

Role Overview Natera Inc. is hiring a Senior Product Manager focused on Oracle Fusion Supply Chain Management (SCM) in San Carlos, CA. This role shapes product strategy for SCM solutions and works closely with teams across the company. The position plays a central part in connecting product development to customer needs and market direction within healthcare technology. What You Will Do Guide the strategy and roadmap for Oracle Fusion SCM products Work with engineering, operations, and other teams to deliver new features and improvements Identify opportunities to advance SCM solutions based on market trends and customer feedback Ensure product development aligns with Natera’s goals and the needs of healthcare clients About Natera Natera develops technology-driven solutions for the healthcare sector, with a focus on innovation and customer impact.

Join Our Mission to Safeguard Humanity!Vaxcyte is a pioneering clinical-stage vaccine innovation company dedicated to engineering high-fidelity vaccines aimed at protecting humanity from the dire consequences of bacterial diseases. Our mission to combat and eradicate bacterial infections—including invasive pneumococcal disease, Group A Strep, and Shigella—is just the beginning. With a clear and defined path to success, Vaxcyte is positioned to make a lasting impact. Our Approach: At Vaxcyte, what we do is as crucial as how we achieve it. Our work is guided by four core values: *RETHINK CONVENTION: We leverage creative and intellectual diversity to innovate and redefine the delivery of vaccines. *AIM HIGH: We pursue our ambitious goal of developing the most complex biologics ever attempted for the protection of humanity. *LEAD WITH HEART: At Vaxcyte, we prioritize kindness and inclusivity in our collaborative efforts, fostering vigorous discussions that align with our business objectives. *MODEL EXCELLENCE: Our shared challenge necessitates a commitment to integrity, accountability, equality, and clarity in all communications and decisions.Summary:Vaxcyte is seeking a dynamic and skilled individual to join our Vaccine Product Development team as a Stability Manager within the Quality Control Unit. This role is vital for managing the stability program for various projects in preclinical and clinical development.In this position, you will play an essential role in implementing and upholding cGMP Stability for all stages of clinical development. Your primary responsibilities will include overseeing stability studies for individual projects and analyzing stability data. You will collaborate closely with QC team members in a highly cooperative and cross-functional environment. The ideal candidate will bring extensive stability experience, ensure compliant operations and documentation, promote open communication, and adopt data-driven methodologies.

Position Summary The Senior Marketing Manager for NIPT will be responsible for crafting and implementing innovative marketing strategies aimed at enhancing the adoption of Natera’s genetic testing solutions, user experience offerings, and educational tools for patients. This is an exceptional opportunity to be part of a dynamic marketing team, developing multi-channel campaigns that make a significant impact on healthcare for countless patients. This position reports directly to the Director of NIPT and Hereditary Cancer Marketing. Primary Responsibilities Market Awareness and Adoption: Create and execute comprehensive marketing plans that amplify awareness and promote critical Panorama NIPT and Vistara Single-Gene NIPT messaging through effective marketing and sales channels. Develop and implement healthcare provider (HCP) and patient marketing campaigns, content, and engagement strategies to effectively communicate the value and foster the adoption of Panorama, Vistara, and related support services. Present marketing campaigns, their progress, and performance metrics to internal stakeholders to ensure alignment with overarching business objectives and facilitate campaign optimization. Cross-Functional Collaboration: Work closely with various departments to align marketing strategies and initiatives with business goals, ensuring seamless integration of marketing efforts across the organization.