Scientist I

We are seeking a motivated and detail-oriented Scientist I to join our dynamic team in Cambridge. The ideal candidate will have a strong background in scientific research, with a passion for innovation and problem-solving. This entry-level role offers an exciting opportunity to contribute to groundbreaking projects and advance your career in a collaborative environment.

Your Impact at Lila In this pivotal role, you will spearhead the innovation and validation of advanced pooled assays utilizing mammalian cells. Your work will encompass everything from proof of concept to automated screening processes, enabling the generation of intricate, high-dimensional datasets. This position involves collaboration across cell biology, protein design, and nucleic acid teams to facilitate biologic development programs, focusing on the rapid assessment of binding, stability, function, and immunogenicity of diverse biologics. What You'll Be Building Create next-generation mammalian display-based assays for binding, stability, function, and immunogenicity. Implement cutting-edge multiomic, single-cell, and in situ sequencing workflows to design innovative, highly multiplexed assays. Collaborate with protein design, nucleic acid, and automation teams to leverage these workflows in biologics development. Closed-Loop Experimentation and Execution: Work closely with engineering and automation teams to architect automated, high-throughput experimentation platforms that yield data-rich workflows. Join forces with the AI team to conduct iterative experiments in real time, facilitating rapid optimization and discovery cycles. Collaborate, Lead & Communicate: Engage with cell biologists, synthetic biologists, automation engineers, protein design scientists, and data scientists to document systems, share insights, and refine best practices in autonomous science. Mentor junior scientists, align project milestones with internal and external collaborators, contribute to intellectual property and publications, and present findings across the organization. What You’ll Need to Succeed Ph.D. in Chemical/Biomedical Engineering, Biochemistry, Pharmaceutical Sciences, Immunology, or a related discipline (or M.S./B.S. with 5–8+ years of relevant industry experience). Proficiency in the development and/or application of mammalian display or similar pooled mammalian systems (perturb-seq, MPRA, etc.). Experience in designing, executing, and analyzing single-cell, in situ, or multiomic sequencing experiments. Expertise in creating complex libraries of defined sequences in mammalian cells. Experience in designing, executing, and analyzing flow cytometry and sorting experiments. Familiarity with next-generation sequencing (NGS) based experimental design and analysis.

Join Integrated Resources Inc. as an Associate Scientist I, where you will contribute to innovative scientific research and development projects. As a pivotal part of our team, your role will involve conducting experiments, analyzing data, and collaborating with multidisciplinary teams to advance our scientific objectives.

We are seeking a highly motivated and detail-oriented Associate Scientist I to join our dynamic team in Cambridge. The ideal candidate will assist in the design and execution of experiments, analysis of data, and contribute to various projects within our research initiatives.

AbbVie is seeking a talented and motivated Associate Scientist II or Scientist I to join our dynamic In Vivo Pharmacology team in Cambridge. As part of our innovative research environment, you will play a crucial role in advancing our understanding of pharmacological mechanisms through in vivo studies. This position offers an exciting opportunity to contribute to groundbreaking research that has the potential to transform patient care.

Role Overview AbbVie is hiring a Scientist I to join the Immunology Discovery group in Cambridge. This is an entry-level role focused on research that supports new therapies in immunology. The team values creative problem-solvers who want to help drive scientific progress. What You Will Do Collaborate with scientists on research projects in immunology Apply modern laboratory techniques to investigate immune system pathways Contribute data and insights to support the development of new therapies Work as part of a team committed to advancing scientific understanding Location This position is based in Cambridge.

Join our team at Integrated Resources Inc. as an Associate Scientist I, where you will have the opportunity to contribute to innovative research and development projects. This entry-level position is perfect for recent graduates or individuals looking to launch their careers in the scientific field. You will collaborate with experienced scientists, engage in hands-on laboratory work, and assist in conducting experiments that drive our mission forward.

Your Impact at Lila The Scientist I/II, Process Chemistry will utilize cutting-edge process chemistry methodologies to enhance Discovery Chemistry initiatives across Lila’s diverse platform. This role emphasizes reaction and reactor engineering, process design, high-throughput experimentation, and digital chemistry workflows aimed at small molecules and associated molecular constructs. We seek a hands-on scientist who possesses a robust background in synthetic and process chemistry, complemented by an engineering mindset and experience in developing scalable, data-driven experimental workflows. Collaboration is key in this role; you will work closely with teams in Discovery Chemistry, analytical chemistry, automation, platform engineering, and AI/computational science to design, implement, and refine reaction and process workflows. These improvements will enhance the speed, reliability, and scalability of chemical transformations. The Scientist I/II will play a crucial role in bridging early-stage discovery chemistry with contemporary process development by establishing efficient, digitally enabled, and automation-friendly methods for reaction screening, process optimization, and chemistry execution. This position is perfect for a scientist passionate about the convergence of chemistry, engineering, high-throughput technologies, process intensification, and digital experimentation and eager to contribute to the evolution of next-generation process chemistry capabilities beyond traditional methods. What You Will Be Building Design, execute, and optimize process-relevant chemical transformations that advance Discovery Chemistry programs and the creation of small molecules. Develop reaction and process workflows with a focus on engineering rigor, scalability, reproducibility, throughput, and data integrity. Implement high-throughput experimentation (HTE) for reaction screening, process optimization, condition scouting, and assessment of process-relevant variables. Create and execute workflows that integrate reaction setup, process screening, workup, analytical readout, and data capture into streamlined experimental cycles. Contribute to the design of digitally enabled process chemistry workflows, including structured experimental data generation, electronic documentation, and the integration of chemistry data into computational and AI-ready systems. Collaborate with automation and platform teams to refine reaction and process workflows for robotics-enabled experimentation.

Join AbbVie, a global biopharmaceutical company, as a Senior Scientist I in our Neuroscience division specializing in Biologics Screening. In this role, you will lead innovative research efforts to develop therapies that address unmet medical needs in the field of neuroscience.

Join AbbVie as a Senior Scientist I in the field of siRNA in vitro biology. In this role, you will leverage your extensive knowledge and skills in molecular biology to contribute to innovative research and development projects. Collaborate with a team of dedicated scientists to explore new therapeutic avenues and advance our understanding of RNA interference.

Your Impact at Lila As a Scientist I/II in Organic Chemistry, you will play a pivotal role in the development, execution, and optimization of cutting-edge chemical transformations that enhance Discovery Chemistry initiatives across Lila Sciences. Your focus will be on the rapid synthesis of small molecules and a diverse range of chemical compounds. This position is tailored for an experimental organic chemist who possesses a robust foundation in synthetic chemistry, complemented by practical experience in high-throughput experimentation (HTE), reaction workup, and analytical characterization. Collaborating closely with teams specializing in Discovery Chemistry, analytical chemistry, automation, screening, and AI/computational methods, you will aid in constructing and implementing efficient chemistry workflows designed to expedite molecular design–make–test–analyze cycles. The Scientist II will be integral to reaction development, analog generation, and route execution utilizing contemporary organic chemistry techniques that are compatible with scalable, data-driven, and increasingly automated discovery environments. This role is ideal for a chemist passionate about addressing synthetic challenges at the intersection of reaction innovation, high-throughput experimentation, process efficiency, and analytical insight, and who is driven to contribute to the evolution of next-generation discovery workflows that extend beyond conventional bench chemistry. What You'll Be Building Design and optimize chemical transformations pertinent to Discovery Chemistry programs, with a strong emphasis on the swift synthesis of small molecules and analog series. Utilize modern synthetic organic chemistry methodologies to facilitate efficient exploration of a wide spectrum of structurally diverse and medicinally relevant chemical spaces. Plan and execute multi-step synthesis, reaction optimization, workup, purification, and compound characterization to support molecular discovery campaigns. Develop and implement HTE workflows aimed at reaction screening, condition optimization, reagent evaluation, and rapid assessment of transformation scopes. Establish robust methodologies for reaction setup, workup, sample preparation, and analytical readout to support rapid and information-rich experimentation. Employ analytical tools such as chromatography, NMR, and other related methods to evaluate reaction performance, characterize products, and inform synthetic strategies. Contribute to the evolution of practical and scalable chemistry workflows that integrate reaction discovery, optimization, and downstream compound generation.

COMPANY DESCRIPTION Flagship Pioneering is a leading bioplatform innovation firm dedicated to inventing and building transformative companies that aim to make a significant impact on the world. By merging top-tier scientific talent with entrepreneurial visionaries, we mobilize the resources necessary to support bold innovations. Our endeavors in human health, sustainability, and beyond accelerate scientific advancements across a spectrum of fields, including disease detection and treatment, nature-positive agriculture, and cutting-edge AI applications. What distinguishes Flagship is our unique capacity to propel science and technology forward by integrating innovation, company formation, and capital investment under one roof—an approach that is largely unprecedented. Our scientific pioneers, entrepreneurial leaders, and expert capital managers are aligned in a structured process that facilitates transformative innovation for the benefit of both humanity and the planet. We have founded companies that tackle some of society's most pressing challenges, including delivering vaccines to billions during the COVID-19 pandemic, finding cures for chronic diseases, enhancing health outcomes, and fostering sustainable agricultural practices. Flagship Pioneering has been recognized twice on FORTUNE’s “Change the World” list, acknowledging our positive social and environmental contributions, and we have also been honored on Fast Company’s annual list of the World’s Most Innovative Companies. THE ROLE We are on the lookout for a Senior Scientist to spearhead the design, characterization, and optimization of aerosolizable particle systems. This pivotal role involves developing a comprehensive understanding of engineered particles during their generation, dispersion, and transport in air, and translating that knowledge into robust and scalable material and system designs. The Senior Scientist will operate at the intersection of materials science, aerosol physics, and experimental engineering. You will lead the development of aerosol testing capabilities, shape experimental strategies, and connect particle design with airborne performance. This individual will play a vital role in establishing core methodologies and driving projects from concept to validation. In this highly collaborative position, you will work closely with formulation, process development, and hardware teams to ensure seamless integration between particle design, production processes, and real-world deployment challenges.

Role overview Lila Sciences seeks a Scientist I/II in Drug Delivery Chemistry for its Cambridge, MA location. This role centers on advancing drug delivery systems that align with the company’s broader research objectives. Key responsibilities Collaborate with fellow researchers to design and refine drug delivery technologies. Apply chemistry expertise to enhance scientific strategies and laboratory processes. Contribute to projects focused on improving patient outcomes through innovative drug delivery solutions. Location This position is based in Cambridge, Massachusetts.

We are seeking a highly motivated and experienced Senior Scientist I to join our Pipeline Development & Targeted Delivery team at AbbVie. In this pivotal role, you will lead innovative research efforts aimed at advancing our therapeutics pipeline. You will collaborate with cross-functional teams to design experiments, analyze data, and contribute to strategic decision-making processes.

Make an Impact at Lila Sciences As a pivotal member of our Physical Sciences division, you will spearhead the design and implementation of cutting-edge simulation methodologies aimed at modeling transport phenomena, kinetics, rare events, and reaction networks. Your innovative approaches will be integrated with artificial intelligence platforms to facilitate groundbreaking materials discovery. Your contributions will be essential in predicting, designing, and managing the behaviors of intricate materials and molecular systems, leveraging the power of agentic AI. Collaborating with our diverse teams, including experts in machine learning and materials science, you will help bridge theoretical research and practical experimentation. What You Will Create Enhance and develop molecular dynamics and Monte Carlo algorithms to effectively capture rare events, non-equilibrium processes, transport phenomena, and intricate reaction networks. Create scalable simulation workflows that merge statistical mechanics techniques with machine-learned interatomic potentials and agentic AI systems. Devise methods for synchronizing dynamic simulations with experimental observations to enable automated lab verification and discovery. Work collaboratively with computational scientists, machine learning specialists, and platform engineers to elevate the accuracy and scalability of simulation-driven material discoveries. Establish reproducible and modular software pipelines for statistical mechanics and dynamics simulations, optimized for high-performance computing and cloud environments. Qualifications for Success A PhD or equivalent research/industry experience in Physics, Chemistry, Chemical Engineering, Mechanical Engineering, Applied Mathematics, or related fields. A robust background in statistical mechanics, free energy calculations, reaction mapping, non-equilibrium dynamics, and rare-event sampling techniques. Proven expertise in molecular dynamics, Monte Carlo simulations, and/or kinetic simulation software frameworks (e.g., LAMMPS, GROMACS, OpenMM, HOOMD). Strong programming skills and experience in scientific computing (Python, C/C++, MPI, CUDA, etc.). Experience in executing and automating simulations on high-performance computing (HPC) and/or cloud platforms at scale. Bonus Qualifications A solid publication record showcasing the application of advanced statistical mechanics or dynamics simulations to molecular and materials systems, including molecular/biomolecular systems and solid-state materials and interfaces. Experience in integrating dynamics simulations with data-driven, AI-based, and/or agentic frameworks.

Join our innovative team as a Senior Scientist where you'll drive critical research projects and make a significant impact in the field. We are seeking a highly motivated individual with a passion for scientific discovery and a strong background in relevant disciplines.

Your Role at Lila SciencesJoin our innovative Physical Sciences division, where you will spearhead the development of intelligent agent-driven systems designed to enhance AI-accelerated and AI-orchestrated process engineering across diverse industrial applications. In this pivotal role, your mission will be to create methodologies empowering AI agents to reason, design, simulate, optimize, and operate complex physical and chemical processes using both traditional and machine learning-driven process engineering tools. You will focus on building agentic infrastructures that facilitate AI systems in planning and executing multi-step process engineering workflows, which include process synthesis, flowsheet generation, steady-state and dynamic simulation, control strategy design, and techno-economic evaluation. Your contributions will significantly influence how Lila's scientific superintelligence addresses real-world challenges through closed-loop autonomous process engineering.Your ContributionsDesign and implement agentic frameworks supporting comprehensive process engineering workflows, encompassing process setup, simulation, optimization, and analysis.Create AI agents capable of autonomously planning, executing, and refining process engineering tasks utilizing existing tools such as steady-state and dynamic simulators, optimizers, and data systems.Investigate agentic strategies for advanced objectives, including process intensification, control co-design, real-time optimization, and closed-loop learning informed by operational data.Enhance the robustness, interpretability, and reproducibility of agent-driven process engineering workflows; develop internal tools for debugging, observability, validation, and auditability.Collaborate with interdisciplinary teams to apply agentic process engineering across a wide range of industrial applications.

We are seeking a motivated and detail-oriented Bench Scientist to join our dynamic team in Cambridge. This entry-level position is an excellent opportunity for recent graduates or those new to the field of scientific research. As a Bench Scientist, you will play a crucial role in conducting experiments, analyzing data, and contributing to innovative projects. If you are passionate about science and eager to learn, we encourage you to apply!

Join Artech Information Systems LLC as a Scientist in Cambridge, where you will contribute to groundbreaking research and innovative solutions in a collaborative environment. Your expertise will help drive scientific advancements and enhance our projects.