Research Infrastructure and Software Engineer

Role OverviewJoin Healx as a passionate Platform Engineer, where your expertise will be pivotal in constructing cloud infrastructure and crafting production pipelines that advance our AI-driven drug discovery initiatives. You will play a crucial role in merging infrastructure with scientific software, engaging in design, development, and support of cloud systems, while also collaborating closely with bioinformaticians, machine learning engineers, and data scientists to implement effective data pipelines.As part of a compact, dynamic engineering team, you will take ownership of your tasks, drive innovation swiftly, and engage in collaborative pair programming. Your work will have a significant impact on the future of AI drug discovery, helping to find treatments for patients suffering from rare diseases. We encourage you to attach a cover letter detailing why you believe you would excel in this position. Our Approach to AI DevelopmentOur engineers leverage AI coding tools to address challenges and efficiently implement systems, while maintaining accountability for system design, implementation, and code testing. We prioritize rapid development alongside a deep understanding of the systems we create and manage. About HealxHealx is a pioneering tech bio company harnessing AI to transform drug discovery. With over 10,000 rare diseases impacting 400 million individuals globally, 90% of which lack approved treatments, Healx is committed to revolutionizing drug discovery to support patients in need. By integrating data, artificial intelligence, and profound pharmacology knowledge, we aim to develop treatments more swiftly and cost-effectively than traditional methods. We firmly believe that diversity and inclusion are fundamental to our mission of assisting individuals with rare diseases. At Healx, we encourage applications from candidates of all backgrounds and experiences.

Quotient Therapeutics is a private biotechnology company developing new therapies by working with natural somatic genetic diversity in patients. The team applies expertise in somatic genomics to advance biopharmaceutical research, running both internal and collaborative programs. Founded by Flagship Pioneering, Quotient Therapeutics is part of a network of over 100 ventures launched in the last two decades, each tackling challenges in biology, industry, and engineering. Role overview This mid-level AWS Platform Engineer position is based at the Chesterford Research Campus near Cambridge, UK. The role focuses on building and improving cloud infrastructure that supports genomics-driven drug discovery. As part of the Data Infrastructure team, the engineer will work alongside biologists, informaticians, and software engineers to maintain data pipelines, applications, and AI/ML workflows across the organization. The position reports to the Head of Data Engineering. Candidates must have the right to work in the UK. What you will do Manage and enhance the AWS-based platform for development and production environments. Develop and maintain infrastructure-as-code, primarily using AWS CDK, to provision and manage cloud resources. Help build CI/CD pipelines and automation for engineering teams. Support and optimize AWS services including EC2, S3, Lambda, Batch, ECS/EKS, and RDS. Improve observability through better logging, monitoring, alerting, and cost tracking. Troubleshoot issues across infrastructure, pipelines, and applications, collaborating closely with engineers and scientists. Location This position is based at the Chesterford Research Campus near Cambridge, UK.

Join Luminance, a leader in Legal-Grade™ AI for enterprises, and be part of a groundbreaking team that's revolutionizing the legal profession worldwide. With backing from prestigious venture capitalists and accolades like being featured in Forbes AI 50 as one of the 'Most Promising Private AI Companies' and Inc. 5000's 'Fastest Growing Companies in America', we're on the cutting edge of technology.We are on the lookout for an innovative and skilled Infrastructure Engineer to join our Infrastructure Team in a role focused on DevOps and platform engineering. The successful candidate will possess a robust background in cloud-native infrastructure development, emphasizing automation, scalability, and security, as well as a comprehensive grasp of Infrastructure-as-Code (IaC). Your role will be pivotal in designing and evolving Luminance’s AWS platform, modernizing deployment patterns, automating environment creation, and ensuring our systems are reliable, repeatable, and resilient.Key ResponsibilitiesDesign, build, and maintain scalable cloud infrastructure utilizing AWS services including EC2, EKS, RDS/Aurora, ElastiCache, OpenSearch, and CloudFront.Lead the development and adoption of Kubernetes on EKS for managing both production and internal workloads.Architect and implement Infrastructure-as-Code (IaC) pipelines, integrating Terraform or similar tools into CI/CD workflows for environment provisioning, validation, and automated testing.Implement zero-downtime deployment strategies (blue/green, rolling, canary) and automate rollback and recovery processes.Promote continuous improvement in infrastructure, focusing on eliminating single points of failure and enhancing autoscaling, high availability, and managed service adoption across the platform.Collaborate with SRE, Security, and Engineering teams to enhance observability, monitoring, and alerting using tools such as Prometheus, Grafana, and CloudWatch.Work closely with the Security team to incorporate best practices for IAM, secrets management, WAF, and overall posture management.Optimize performance and cloud expenditure through automation and cost visibility dashboards.Participate in on-call rotations, conduct post-incident reviews, and contribute to ongoing operational reliability improvements.

Collaboration Fuels Innovation. Roku is transforming the way the world experiences televisionAs the leading TV streaming platform in the U.S., Canada, and Mexico, Roku aims to power every television globally. We pioneered streaming technology, and our mission is to be the ultimate platform connecting the entire TV ecosystem. We link consumers to their favorite content, enable publishers to grow and monetize vast audiences, and provide advertisers with unique engagement opportunities.From day one at Roku, your contributions will be significant and appreciated. Join our dynamic public company where every team member plays an active role. You’ll have the chance to inspire millions of TV viewers while gaining invaluable experience across diverse areas. About the Role We are developing a next-generation observability and cloud platform that is high-performance, cost-effective, secure, and scalable across multi-region, multi-cloud infrastructures. You will take the lead in architecting and evolving Roku’s observability and cloud infrastructure stack, which encompasses metrics, logs, traces, telemetry pipelines, service mesh, developer experience, and system reliability that support thousands of services and millions of devices. You will be instrumental in driving a vision where developers achieve profound visibility with minimal overhead, onboarding is effortless, and insights are accessible in real-time. Your contributions will directly empower Roku...

Imagine being part of a pioneering organization that fosters, funds, and builds innovative life sciences companies focused on groundbreaking technologies aimed at transforming healthcare and sustainability. Montai Therapeutics is an early-stage biotechnology company that is privately owned, dedicated to developing a unique platform designed to understand and utilize complex molecular interactions to address global health and sustainability challenges. Our multidisciplinary approach combines advanced tools, including machine learning, big data, multi-omics, and high-throughput screening. At Montai, we cultivate a vibrant, forward-thinking culture committed to enhancing human health: We operate as a cohesive unit, characterized by mutual trust, empowerment, and accountability. While we each contribute our strengths, we thrive as a unified team, dedicated to excellence. We embody urgency and tenacity, with a strong belief in our capacity to effect change. We embrace discomfort as a pathway to growth, employing rigorous methods and viewing failures as valuable data points. Diversity in our workforce, thoughts, personalities, opinions, backgrounds, and uniqueness is a priority for us. We maintain a sense of humor to navigate the complexities of our strategic endeavors. About the Role We are in search of a Senior Platform Engineer who will enhance and expand our AWS-based infrastructure that underpins our products and teams. This role entails architecting the foundation that fuels our innovation and growth. You will tackle intricate engineering challenges, streamline automation processes for quicker and more dependable deployments, and construct resilient systems that empower our teams to operate at scale. Why should you consider joining us? Here, you will be at the forefront of genuine innovation, engaging with cutting-edge cloud technologies, challenging the limits of automation, and developing state-of-the-art tools that enable our users and teams to excel. If you are enthusiastic about creating platforms that yield significant impacts and wish to help define the future of technology delivery, this position is tailored for you. What You Will Do Design, build, and maintain AWS infrastructure (ECS, EC2, RDS, S3, IAM, VPC) or equivalent services from alternative cloud providers (GCP, Azure). Develop backend services and integration tools to bolster critical systems. Implement and optimize CI/CD pipelines (GitHub Actions, CodePipeline). Drive automation initiatives to ensure deployments are swift, reliable, and...

Join Cambridge Mobile Telematics (CMT), the leading telematics service provider dedicated to enhancing road safety and improving driver behavior. Our AI-driven platform, DriveWell Fusion®, integrates data from millions of IoT devices, including smartphones, connected vehicles, and dashcams, to provide invaluable insights for auto insurers, automakers, and mobility companies. Headquartered in Cambridge, MA, with global offices in Budapest, Chennai, Seattle, Tokyo, and Zagreb, we are committed to protecting millions of drivers daily.We are on the lookout for a dynamic and collaborative Senior Manager of Engineering to steer our Cloud Infrastructure team. This critical team is responsible for developing and enhancing the core platform services that underpin our telematics products, ensuring a secure, scalable, and robust infrastructure. As a leader, you will work closely with cross-functional engineering and product teams to shape and execute the technical roadmap.

Join our dynamic team at ttp1 as a Senior Platform Engineer. In this pivotal role, you will be responsible for designing, developing, and maintaining scalable platform solutions that enable our innovative projects to thrive. You will collaborate with cross-functional teams to ensure seamless integration and exceptional performance of our systems.

Role overview Speechify seeks a Platform Software Engineer based in Cambridge, MA. This position centers on building and enhancing the core platforms that power Speechify’s applications. The work involves designing, implementing, and refining scalable systems that influence both product development and the overall user experience. What you will do Develop and maintain platform software supporting Speechify’s products Work with engineering, product, and design teams to deliver reliable solutions Improve existing systems for better performance and scalability Share ideas that help shape the direction of Speechify’s technology Requirements Proven experience building high-quality software Ability to collaborate with cross-functional teams Interest in tackling complex technical challenges This is an onsite role in Cambridge, MA.

Join ttp1 as a Platform Engineer in our dynamic Cellular Origins department, where you will play a pivotal role in designing and developing innovative platforms that drive cutting-edge cellular technology. You will collaborate with a talented team of engineers and scientists, contributing your expertise to enhance our products and solutions. This is an exciting opportunity to work in a fast-paced environment where creativity and technical skills are highly valued.

Join Luminance, a trailblazer in Legal-Grade™ AI for enterprises, and seize the opportunity to shape the future of the legal profession globally. With significant backing from prestigious venture capitalists and recognition in Forbes AI 50 and Inc. 5000, our innovative solutions are transforming legal practices worldwide.We are looking for a seasoned IT Infrastructure & Network Engineer to take ownership of enhancing Luminance’s corporate infrastructure. This includes responsibilities for networking, identity management, firewalls, and hybrid cloud services.In this hands-on engineering role, you will focus on creating secure, reliable, and efficient enterprise IT systems that facilitate our internal operations. You will collaborate closely with the Security and Platform teams to ensure our infrastructure is robust, secure, and scalable.

Location: Cambridge, UK. Candidates should live within commuting distance or be willing to relocate for onsite meetings as needed. Role overview Jagex seeks a Senior Cloud Reliability Engineer to help keep RuneScape’s services reliable, scalable, and responsive for players worldwide. This position sits within the Cloud Tech division and collaborates with Game, Central Tech, and Cloud Platform teams. The main focus is to drive reliability, observability, automation, and cloud-native practices across a hybrid-cloud environment. This role combines hands-on production engineering with architectural decision-making. Projects include modernizing services, migrating workloads, and improving systems that directly affect the player experience. The team is committed to delivering reliable live services at scale. What you will do Collaborate with game and development teams to move services toward cloud-native architectures, increasing resilience, security, and cost-effectiveness in live environments. Support migration of workloads from managed VPS environments to Jagex’s cloud platform, with a focus on modernization and uptime. Develop and refine SLIs, SLOs, and error-budget frameworks to measure and communicate service reliability across teams. Design and improve observability and alerting for logs, metrics, and traces, enabling faster detection and resolution of issues. Automate operational tasks such as scaling, failover, and deployments. Build self-healing systems to reduce manual intervention and improve recovery. Drive reliability improvements in Linux-based production systems, reusable Infrastructure as Code modules, and team codebases. Contribute to raising engineering standards within Cloud Tech. Requirements Experience ensuring reliability for large-scale, internet-facing production services. Strong knowledge of AWS services, including VPC, EC2, ECS/EKS, ELB, ECR, Route53, KMS, IAM, and Systems Manager. Background in cloud-native design, workload modernization, and Infrastructure as Code (IaC). Hands-on experience with SLIs, SLOs, incident management, root cause analysis, and resilient system architecture. Practical experience with Debian-based Linux environments, managing VM fleets, and configuration management tools. Familiarity with observability platforms, CI/CD practices, containerization, and programming or scripting in Python or Java. Benefits Comprehensive private healthcare, including dental plan Discretionary annual performance bonuses At least 6% pension contributions Life insurance coverage Enhanced family leave policies

Speechify’s mission is to remove reading barriers and open up learning opportunities for everyone. Our text-to-speech technology supports over 50 million users, turning PDFs, books, Google Docs, news articles, and websites into audio. This helps people read more efficiently and remember more. The product suite covers iOS, Android, Mac, a Chrome Extension, and a Web App. Speechify has earned recognition from Google as Chrome Extension of the Year and received Apple’s 2025 Design Award for Inclusivity. The team is fully distributed, with nearly 200 professionals from companies such as Amazon, Microsoft, and Google, as well as graduates from Stanford and other top universities. Speechify operates without physical offices. Role Overview This Software Engineer position sits within the AI team, focusing on data infrastructure and acquisition. The work spans all aspects of data collection to support model training. The role blends infrastructure, engineering, and research to help build high-quality datasets at petabyte scale, efficiently and cost-effectively. What You Will Do Identify and source new audio data to improve the data ingestion pipeline. Manage and expand cloud infrastructure for data ingestion, currently on Google Cloud Platform (GCP) and managed with Terraform. Work closely with scientists to improve data quality, throughput, and cost, supporting the development of future models. Collaborate with the AI team and leadership to plan and prioritize datasets for upcoming consumer and enterprise products. What We Look For BS, MS, or PhD in Computer Science or a related field. At least 5 years of professional software development experience. Strong skills in bash and Python scripting in Linux environments. Familiarity with Docker and Infrastructure-as-Code, with hands-on experience using a major cloud provider (GCP preferred). Experience with web crawlers and large-scale data processing is a plus. Comfort handling multiple priorities and shifting focus as needed. Clear verbal and written communication skills. Location: Cambridge, United Kingdom (fully remote/distributed team).

LILA Sciences is seeking a Staff DevOps Engineer to lead the design, deployment, and ongoing improvement of infrastructure and delivery systems. This role blends platform engineering, site reliability, and DevOps practices to build scalable, automated systems that support reliable software delivery in cloud and Kubernetes environments. Collaboration is central: work closely with software developers, laboratory scientists, and machine learning engineers to create the backbone for automated scientific analysis and experiment orchestration. Key Responsibilities Design and implement Kubernetes-based infrastructure to support scientific services, machine learning pipelines, and platform workloads. Ensure production hardening, RBAC, network policies, and compliance with Pod Security Standards. Set up and maintain CI/CD pipelines using GitHub Actions or GitLab CI. Apply best practices including build attestations, SBOM generation, dependency scanning, and container image hardening. Apply Infrastructure-as-Code principles with Terraform and Helm. Implement policy-as-code guardrails (using OPA, Kyverno, or Checkov) and enable drift detection. Manage AWS cloud infrastructure, including EKS clusters, IAM with least privilege, VPC/PrivateLink networking, KMS/Secrets Manager, ECR, S3, and centralized logging and monitoring systems. Develop platform tools to improve deployment, observability, and developer workflows, supporting self-service with secure defaults. Drive reliability engineering practices, focusing on SLOs/SLIs, incident response, capacity planning, and performance optimization across the technology stack. Implement software supply chain security, including artifact signing, registry governance, and vulnerability management. Build and maintain QA and testing infrastructure: static analysis, code quality gates in CI pipelines, automated end-to-end and browser-based regression testing, ephemeral environments for pull request validation, and pre-merge quality checks. Automate operational processes and develop tooling in Python or Go to streamline infrastructure operations and integrate telemetry with observability platforms. Requirements Significant experience in DevOps, Site Reliability Engineering, or Platform Engineering within large-scale cloud environments. Proficiency with cloud deployments (AWS, GCP, etc.) using Infrastructure-as-Code tools such as Terraform and Helm, and expertise in containerization. Strong background in CI/CD systems (GitHub Actions, GitLab CI, or Jenkins) and familiarity with GitOps workflows. Advanced scripting skills in Python or similar languages for automation and tool creation. Comprehensive understanding of Kubernetes operations, including deployments, networking, storage, observability, and troubleshooting. This position is based in Cambridge, MA, USA.

Join Roku, a leading streaming platform, as a Senior Software Engineer focused on enhancing our infrastructure, efficiency, and productivity. In this role, you will play a key part in architecting and developing innovative solutions that drive our technology forward. Collaborate with cross-functional teams to optimize system performance and ensure robust reliability in our services.

Location: Cambridge, MA (Eastern Time / UTC -4) Relocation package available or Remote option for Out-Of-State applicantsStart date: ASAPLanguages: English (required)About the RoleJoin Pragmatike, a dynamic AI startup recognized as a Top 10 GenAI company by GTM Capital, founded by esteemed MIT CSAIL researchers. We are currently seeking a Senior Multicloud Engineer who possesses extensive, hands-on experience in architecting, deploying, and managing production infrastructure across AWS, GCP, and Azure. This pivotal role involves working directly on cloud and platform layers to support large-scale, distributed AI systems for Fortune 500 clients.What You'll DoDesign, deploy, and maintain production infrastructure across AWS, GCP, and Azure.Ensure consistent environments through Infrastructure as Code (Terraform preferred).Manage and operate Kubernetes clusters and containerized applications across multiple cloud environments.Architect and oversee cloud networking solutions (VPC/VNet design, peering, load balancing, and private connectivity).Implement robust monitoring, logging, alerting, and incident response protocols for multicloud systems.Enhance performance, reliability, and cost-efficiency across providers using autoscaling and capacity planning strategies.Support AI training and inference workloads in multicloud settings.Diagnose and resolve complex production issues across compute, networking, storage, and Kubernetes layers.Collaborate with AI, backend, and platform teams to ensure seamless integration with production systems.What We're Looking For5+ years of experience as a Cloud/Platform/Infrastructure Engineer.Proven production experience with AWS, GCP, and Azure (strong expertise in at least one).

Teamwork Makes the Stream Work. Transforming TV Viewing with RokuAs the leading TV streaming platform in the U.S., Canada, and Mexico, Roku is on a mission to empower every television worldwide. We pioneered the concept of streaming to the TV, aiming to create a platform that seamlessly integrates all elements of the television ecosystem. Our goal is to connect viewers to the content they love while providing content creators the tools to monetize their audiences and offering advertisers unique engagement opportunities.From the moment you join Roku, you will play a vital role in our team. As a rapidly growing public company, we ensure that every employee feels valued. This is your chance to impact millions of TV streamers globally and gain invaluable experience across various disciplines. Role OverviewWith over 85 million users worldwide, our products are renowned for their intuitive performance and seamless integration. This success is not incidental; our commitment to user-centered design ensures our products are not just functional but also instinctive to use. We strive to simplify the streaming experience for users.We seek a Senior Software Engineer to develop core features for the Roku platform's user interface. The ideal candidate will have experience creating high-performance applications and SDK components, eager to code for a highly popular consumer electronics platform. This position offers significant visibility and the chance to make a substantial business impact, working on components that influence nearly all content streamed on Roku. About Our TeamThis team focuses on customer-centric features that enhance user experience, including cross-platform device interactions, TV and Player-centric user interfaces, and IoT integration with Roku OS. Our product roadmap is designed to accelerate our growth and scalability, delivering innovative features to millions of Roku users worldwide.Our developers and engineers are proactive and driven, taking ownership of their work and finding motivation in their contributions.

Role overview Speechify seeks a Software Engineer focused on Data Infrastructure & Acquisition for its Cambridge, MA office. This position centers on building and improving data pipelines, ensuring the platform’s information remains accurate and current. The work directly supports Speechify’s mission to empower people through technology. What you will do Develop and refine data pipelines with an emphasis on reliability and efficiency Collaborate with team members to strengthen the platform’s data architecture Contribute to solutions that enhance data delivery throughout the platform Collaboration This role involves close partnership with engineers and other colleagues to advance Speechify’s data systems and foster ongoing innovation.

About Flagship Pioneering Flagship Pioneering is a biotechnology company based in Cambridge, MA. The team invents and builds platform companies focused on advancing human health and sustainability. Flagship brings together scientific leaders, entrepreneurs, and experienced capital managers to address challenges ranging from cancer care to sustainable agriculture. The company’s portfolio includes organizations that have vaccinated billions, developed new treatments, and promoted eco-friendly practices. Flagship has been recognized on FORTUNE’s “Change the World” list and featured in Fast Company’s annual “World’s Most Innovative Companies.” Role Overview: Lead Cloud Security and Application Security Engineer This role shapes Flagship’s cloud security and application security engineering practice. Supported by the CISO and Director of Security Engineering, the position focuses on defining and executing cloud posture management, secure software development lifecycle (SSDLC) security, and cloud-side data loss prevention. The engineer will work closely with the Infrastructure & Operations team on cloud architecture and network infrastructure. One of the main responsibilities is to build workflows that use AI and large language models (LLMs) to automate routine security tasks, freeing up time for complex challenges that require human judgment. The position leads technical execution for cloud security and application security across Flagship and its portfolio, partnering with engineering teams to embed security into development pipelines from the start. Key Responsibilities Establish and lead Flagship’s cloud security and application security engineering practice Define cloud posture management, SSDLC security, and cloud-side DLP strategies Collaborate with Infrastructure & Operations on cloud architecture and network infrastructure Develop and implement AI-enhanced workflows using LLMs and intelligent tools Automate recurring tasks to focus on high-impact security work Work directly with engineering teams to integrate security into development pipelines Drive technical execution of cloud security and AppSec across Flagship and its portfolio companies Work Location Cambridge, MA, USA

Join Engine as a Senior Associate in Community OperationsAt Engine, we empower visionary founders who are tackling the world's most critical challenges in areas such as climate change, health, and advanced technologies. Our commitment includes providing robust support through founder programs, access to shared infrastructure and labs, and the opportunity to connect with a diverse national network of corporate partners, investors, and industry experts.