Research Associate in tRNA and mRNA Biology

Nuclera develops technology to make proteins more accessible for researchers. Based in Cambridge, UK, with a presence in Boston, the company’s eProtein Discovery™ platform brings together a benchtop instrument, cloud-based software, and proprietary cartridges. This system supports rapid protein expression, characterization, and purification for life science teams around the world. Role overview The Research Associate in Service Fulfillment supports custom scientific projects and DNA construct amplification using the eProtein Discovery Platform. The role requires careful adherence to Standard Operating Procedures (SOPs) and detailed work instructions to maintain quality and consistency. Success in this position calls for strong organizational skills, attention to detail, and the ability to work independently within set timelines. What you will do Prepare DNA constructs for cell-free protein expression using PCR techniques. Perform protein purification, quantification, SDS PAGE analysis, and either gel filtration chromatography or Surface Plasmon Resonance (SPR) analysis. Run experiments with the eProtein Discovery Platform. Follow established SOPs and work instructions to ensure quality standards are met. Organize and manage large collections of biological samples in a systematic way. Document experimental methods, observations, and results with precision.

We are seeking a detail-oriented and motivated Research Associate to join our dynamic team at Integrated Resources, Inc. As a Research Associate, you will play a pivotal role in conducting research, analyzing data, and supporting various projects that contribute to the advancement of our organization’s goals.Your responsibilities will include collaborating with cross-functional teams, preparing reports, and presenting findings to stakeholders. This position offers an excellent opportunity for professional growth and development in a fast-paced environment.

Join our team at Integrated Resources Inc. as an Associate Research Scientist, where you will contribute to cutting-edge research projects that impact real-world applications. We are looking for passionate individuals eager to innovate and collaborate in a dynamic environment. In this role, you will support senior scientists in the design and execution of experiments, analyze data, and contribute to publications. This is a fantastic opportunity to grow your career in scientific research.

We are seeking a highly motivated Senior Research Associate to join our dynamic team at Integrated Resources, Inc. In this pivotal role, you will conduct advanced research, analyze data, and contribute to innovative projects that drive our mission forward. If you are passionate about scientific research and eager to make an impact, we want to hear from you!

We are seeking a talented and dedicated Senior Research Associate to join our dynamic team in Cambridge. In this role, you will contribute to innovative research projects and collaborate with interdisciplinary teams to drive impactful findings.

Harvard University is seeking an innovative and strategic Associate Director of Research to lead groundbreaking research initiatives. The ideal candidate will possess a deep understanding of research methodologies, strong leadership skills, and a passion for academic excellence. This role involves collaborating with faculty and students to enhance research output and drive impactful scholarship.

Join our dynamic team at Integrated Resources Inc. as a Senior Neurology Research Associate, where you will play a pivotal role in advancing groundbreaking research in neurology. You will collaborate with top-tier professionals, contributing to innovative projects that drive the future of neurological health.

Join Integrated Resources, Inc. as a Pharmaceutical Research Associate, where you will play a vital role in advancing medical research and drug development. You will collaborate with a team of scientists and researchers to assist in the design and execution of clinical trials, ensuring the integrity and accuracy of data collection.Your contributions will help pave the way for innovative therapies that make a difference in patients' lives. Ideal candidates are detail-oriented, possess strong analytical skills, and have a passion for the pharmaceutical industry.

COMPANY DESCRIPTION We are a pioneering start-up dedicated to transforming the landscape of chemical discovery. Our innovative platform integrates artificial intelligence with a state-of-the-art laboratory discovery pipeline to redefine molecular formulation development. Our interdisciplinary team is exploring uncharted chemical territories, facilitating significant advancements in drug delivery, agricultural formulations, and sustainable, high-performance industrial chemicals. Backed by Flagship Pioneering, a leader in biotechnology origination, we have fostered over 115 scientific ventures in 25 years, generating more than $20 billion in aggregate value, 500+ patents, and over 50 clinical trials for groundbreaking therapeutic agents. THE ROLE We are on the lookout for a passionate and skilled Senior Research Associate or Associate Scientist to enhance our formulation discovery platform by characterizing biomolecules. This position involves utilizing a range of biophysical and biochemical methodologies to analyze the effects of formulations on biomolecular integrity, aggregation, and functional stability. You will collaborate closely with chemists and machine-learning experts to produce high-quality experimental data that drives formulation design and predictive modeling initiatives. The ideal candidate will possess a solid background in biochemistry, structural biology, or biopolymer engineering, complemented by practical experience with analytical instrumentation for biomolecular characterization. KEY RESPONSIBILITIES Conduct experiments assessing biomolecular stability and solubility across various formulation conditions. Evaluate cargo structural integrity and folding utilizing circular dichroism (CD) spectroscopy and complementary biophysical techniques. Measure biomolecular interactions and stability through spectroscopy, dynamic light scattering, and electrophoretic methods. Prepare samples for diverse external workflows to evaluate molecular integrity and degradation. Experimental Pipeline Support Collaborate with formulation chemists to investigate cargo-formulation interactions across different experimental contexts. Generate high-quality experimental datasets to assist internal modeling and data analysis processes. Support laboratory instrumentation maintenance and troubleshooting. Maintain organized laboratory records, analyze results, and communicate findings effectively to cross-functional teams.

Join the Cambridge Boston Alignment InitiativeThe Cambridge Boston Alignment Initiative (CBAI) is a nonprofit organization dedicated to pioneering research and educational initiatives aimed at ensuring a safe and beneficial transition to advanced AI systems. Our mission focuses on producing original research and accelerating AI safety through comprehensive fellowship programs.Since our initial summer fellowship cohort, we have achieved significant milestones, including published papers at prominent conferences such as NeurIPS and ICLR. As we enter 2026, we are poised for rapid growth, planning multiple fellowship cycles and expanding our team significantly.Refer candidates to us, and if hired, you will receive a $5,000 referral bonus!Your RoleAs a Research Program Associate, you will collaborate closely with Research Managers, mentors, and program leadership to design and refine the frameworks that empower fellows to excel in their research. This is a pivotal program-building position where you will create systems for mentor matching, research goal tracking, progress assessment, and problem-solving support for fellows.Program Design & Development (0.6 FTE)Enhance CBAI's fellow selection process and program deliverables.Identify effective outreach channels and manage outreach campaigns for future iterations.Develop evaluation frameworks to assess fellow progress and program effectiveness.Implement structural improvements based on feedback from fellows, mentors, and research managers.Assist in the planning and execution of fellowship events, such as speaker series and poster days.Fellow & Mentor Experience (0.4 FTE)Design and oversee the onboarding process for mentors, ensuring a positive experience.

COMPANY DESCRIPTION Flagship Pioneering is a transformative innovation platform that unites visionary scientific minds with entrepreneurial leaders to create and cultivate groundbreaking companies that aim to change the world. We provide the necessary capital and support to enable these innovators to undertake ambitious projects that advance human health, sustainability, and more. Our diverse portfolio spans critical areas including disease detection and treatment, sustainable agriculture, and pioneering applications of artificial intelligence that foster technological advancements. What distinguishes Flagship is our unparalleled ability to integrate scientific innovation, company creation, and strategic capital investment, offering a cohesive ecosystem that facilitates progress. Our founders, leaders, and capital managers collaborate through a structured process designed to foster innovation and enhance life on Earth. Our portfolio companies have tackled some of the world’s most pressing challenges: from vaccinating billions against COVID-19 to curing complex diseases, enhancing human health, preventing illness, and improving agricultural resilience and sustainability. Flagship has been recognized multiple times on FORTUNE’s “Change the World” list and has earned accolades on Fast Company’s annual list of the World’s Most Innovative Companies. THE ROLE We are seeking a dedicated Senior Research Associate to join our formulation and product development team. This critical position will focus on the design, screening, and optimization of dried powder formulations. The successful candidate will take a hands-on approach to executing formulation strategies utilizing techniques such as lyophilization and spray drying, while bringing experimental precision, physical insights, and data-driven decision-making to our early-stage platform development. The Senior Research Associate will collaborate closely with process development partners to create stable, robust, and scalable powder formulations. This role will also involve experimental design, data interpretation, and establishing best practices for formulation screening, characterization, and documentation within a dynamic early-stage environment. KEY RESPONSIBILITIES Design, execute, and optimize dried powder formulations using lyophilization and spray drying, focusing on stability, reproducibility, and performance across various formulations.

Join our innovative team at Flagship Pioneering Inc., where we are at the forefront of therapeutic discovery. As a Senior Research Associate, you will play a critical role in advancing our understanding of novel therapeutic pathways and contribute to groundbreaking research in the life sciences.

We are seeking a dedicated and detail-oriented Research Associate I / Cell Culture Technician to join our dynamic team. This role is pivotal in supporting our research initiatives through precise cell culture techniques and laboratory procedures. The ideal candidate will be responsible for maintaining cell lines, performing assays, and assisting in various research projects.

About eGenesiseGenesis is an innovative clinical-stage biotechnology company dedicated to developing human-compatible engineered organs to tackle the critical global organ shortage. Our proprietary genome engineering platform facilitates extensive, multiplex gene edits aimed at removing major biological barriers, incorporating protective human transgenes, and inactivating endogenous retroviruses. Our flagship program, EGEN-2784, a genetically engineered porcine kidney, is currently undergoing evaluation in a multi-patient Expanded Access study at Massachusetts General Hospital (MGH). Headquartered in the vibrant city of Cambridge, MA, eGenesis is at the forefront of pioneering medical solutions.As the Lead Clinical Research Associate, you will spearhead site monitoring activities and oversee Clinical Research Associates (CRAs) for designated clinical trials. Collaborating closely with Clinical Operations leadership and cross-functional teams, you will ensure that studies are executed in strict adherence to protocols, ICH-GCP guidelines, regulatory requirements, and our company Standard Operating Procedures (SOPs).

About Serif Biomedicines, Inc. Serif Biomedicines, Inc. is a privately held biotechnology company based in Cambridge, MA. The team focuses on developing gene therapies for diseases that currently lack effective treatments. Founded by Flagship Pioneering, Serif is part of a network that has launched over 100 companies in the life sciences, including Moderna, Syros Pharmaceuticals, and Generate Biomedicines. Position Overview The Research Associate in Molecular Biology will contribute to the development of programmable medicines. This position suits a molecular virologist or biochemist with hands-on experience in nucleic acid production, characterization, and molecular cloning. Scientific rigor and a collaborative approach are essential. The role involves working closely with others to advance nucleic acid therapeutics in a setting that values curiosity and innovation. Main Responsibilities Plasmid Production: Design, carry out, and troubleshoot molecular cloning for inserts of various lengths and compositions. Ensure plasmid sequences meet specifications. Inventory Management: Organize storage of produced materials. Keep accurate electronic records of material details and storage locations. Enzymatic Reaction Optimization: Improve and troubleshoot enzymatic reactions to boost nucleic acid yield and purity. Nucleic Acid Production: Follow and refine protocols to produce high-quality DNA and RNA with different expression cassettes.

Senior Research Associate in Chemical BiologyLocation: Cambridge, MA, USACompany: Flagship Pioneering, Inc. (FL116) About FL116 FL116, backed by Flagship Pioneering, focuses on advancing biomolecule synthesis. The team is developing a platform aimed at changing how research, diagnostic, and therapeutic molecules are manufactured. Role Overview The Senior Research Associate in Chemical Biology will join a collaborative group dedicated to applying chemical approaches to biological questions. This position centers on enzyme-mediated biomolecular synthesis, with attention to both mechanistic and molecular details. Main Responsibilities Design and conduct high-throughput experiments to study enzyme-substrate interactions Characterize biomolecular products using established and emerging techniques Support development of scalable assays to expand platform capabilities What We Look For Strong experimental skills and attention to detail Intellectual curiosity about the chemical nature of biological systems Interest in manipulating and measuring biological activities at the molecular level Comfort working in a hands-on, execution-focused, and pipeline-driven setting Motivation to grow with a rapidly evolving technology platform Work Environment This role offers the chance to build expertise at the intersection of chemistry and biology within a collaborative startup supported by Flagship Pioneering. The team values problem solvers who enjoy working on challenging scientific questions and developing new tools for biotechnology and therapeutics.

Join Integrated Resources Inc. as an Associate Scientist III in Cambridge, where you'll contribute to groundbreaking scientific research and development. In this role, you will collaborate with a dynamic team to analyze and interpret data, develop experimental protocols, and ensure the highest standards of quality control. Your expertise will play a crucial role in advancing our innovative projects and achieving scientific excellence.

Lila Sciences seeks an Associate Engineer to join the Research Operations team in Cambridge, MA. This team develops high-throughput methods that support scientific discovery across multiple disciplines. The position centers on hands-on work with materials characterization, using advanced tools such as spectroscopy and microscopy. This role provides direct exposure to automation technologies while supporting projects that influence the company’s direction. It suits candidates interested in expanding their engineering skills and building a strong base in scientific operations. Key responsibilities Perform materials characterization using SEMXRF, XRD, Optical Microscopy, Nanoindentation, and Profilometry. Prepare reagents, solutions, electrolytes, samples, and consumables to support experiments across shifts. Follow standard operating procedures to maintain accuracy and consistency. Monitor workflow, troubleshoot routine issues, and escalate concerns to keep operations steady between shifts. Record and organize experimental data with care. Identify and suggest ways to improve efficiency and streamline shift operations. Report unusual results or observations to scientists for review. Collaborate with scientists and engineers on projects spanning life sciences and physical sciences. Location This position is based in Cambridge, MA, USA.

Your Contribution at Lila Sciences Lila Sciences is actively seeking a dedicated (Senior) Research Associate to become an integral part of our dynamic Life Sciences team. This pivotal role will be centered around the formulation of lipid nanoparticles (LNPs), their functionalization with targeting ligands, and the characterization of the resulting targeted LNPs (tLNPs). The ideal candidate will possess substantial hands-on experience in LNP formulation and characterization, bioconjugation, protein characterization, and automation technologies. Your expertise will significantly enhance our understanding of the delivery space, enabling a high-throughput closed-loop screening cascade for tLNPs. You will work collaboratively with professionals across protein, cell biology, automation, chemistry, machine learning, and data science teams to establish advanced tools for targeted nucleic acid delivery. Your Key Responsibilities Design, execute, and characterize LNP formulations utilizing various scales and mixing modalities (e.g., DLS, ribogreen, TNS). Develop and optimize high-throughput ligand conjugation and purification methodologies, leveraging automation and robotics to maximize throughput. Collaborate with cell assay and antibody experts to screen candidates across diverse tissue targets in in vivo models. Engage with chemists, biologists, engineers, and data scientists to document processes, share insights, and refine best practices in autonomous flow chemistry. Create, implement, and uphold Standard Operating Procedures (SOPs) for both existing and emerging lab processes. Your Qualifications for Success MSc in Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences, or a closely related field with 3+ years of hands-on experience in targeted LNP production or a BSc with 5+ years of relevant experience. Industry experience is highly desirable. Strong proficiency in bioanalytical techniques (e.g., DLS, fluorescence spectroscopy, electrophoresis, in vitro assays). Experience in protein and antibody design and characterization. Familiarity with automation and high-throughput workflows is preferred. Exceptional troubleshooting, communication, and collaboration skills, with a proven ability to work effectively across interdisciplinary teams. About Lila Sciences Lila Sciences is at the forefront of innovation as the world's first scientific superintelligence platform and autonomous laboratory focused on life sciences, chemistry, and materials science. We are pioneering a new era of limitless discovery by harnessing AI capabilities to enhance every facet of the scientific method. Our mission is to leverage scientific superintelligence to address humanity's most pressing challenges.