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Principal CADD Scientist

On-site Full-time

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Experience Level

Mid to Senior

Qualifications

PhD in Computational Chemistry, Structural Biology, or a related field. This role may also be suitable for PhD-level scientists with degrees in organic or medicinal chemistry who have extensive lab experience and transitioned into industry roles in CADD. Deep understanding of structure-based drug design and protein-ligand interactions is essential. Proficiency with industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite is required. A minimum of 5+ years of industry experience as a CADD scientist in pharma or biotech is mandatory, with hands-on experience in active drug discovery programs.

About the job

At Genesis Molecular AI, we are on a mission to transform the landscape of drug discovery by forming a premier computational chemistry team that leverages advanced machine learning techniques and biophysical simulations. We are actively looking for a Principal CADD Scientist to collaborate with our scientists in our cutting-edge wet lab and coordinate with our remote computational chemistry and CADD science teams throughout the United States.

Key Responsibilities

  • Employ both established and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a diverse range of targets, including innovative targets with minimal chemical precedents.

  • Implement strategies such as virtual screening, molecular simulations, and predictive analytics for potency and ADMET to inform critical decision-making in drug development.

  • Work collaboratively with medicinal chemists on molecular design and the formulation of project-specific computational methodologies.

  • Serve as a liaison among teams, ensuring effective communication between computational chemistry and medicinal chemistry groups to facilitate seamless information exchange and collaborative decision-making.

  • Thrive in a dynamic environment that fosters innovation and rapid iteration.

Qualifications

  • PhD in Computational Chemistry, Structural Biology, or a related discipline. This role is also suitable for PhD-level professionals in organic or medicinal chemistry with substantial lab experience who have transitioned into CADD roles.

  • In-depth knowledge of structure-based drug design and protein-ligand interactions.

  • Expertise in using industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite.

  • A minimum of 5 years of relevant industry experience as a CADD scientist in pharmaceuticals or biotechnology, with direct involvement in active drug discovery projects.

  • While onsite presence in our San Diego lab is preferred for collaboration, we welcome applicants interested in remote opportunities.

What We Offer

  • Competitive salary and benefits package

  • Comprehensive health care plans (including medical, dental, and vision, fully covered for employees)

  • Eligibility for stock options

About Genesis Molecular AI

Genesis Molecular AI is at the forefront of revolutionizing drug discovery through the integration of advanced computational techniques and machine learning. Our dedicated team is committed to developing innovative solutions that enhance the efficiency and efficacy of drug development processes.

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