Mechanical Design Engineer - Diagnostics

Isomorphic Labs is hiring a Head of Translational Sciences, Drug Design for its Cambridge, MA site. This senior leader will guide the translational strategy across the drug discovery portfolio, working closely with teams at the intersection of biology, artificial intelligence, and medicine. The position plays a central role in shaping how new therapies are advanced and how disease mechanisms are understood within the organization. Role overview This leadership role focuses on driving translational approaches for drug design. The Head of Translational Sciences will collaborate with colleagues to advance projects from early discovery through clinical evaluation. The team’s work includes strengthening biological insights into disease, supporting the selection of drug targets, and developing biomarkers to track pharmacodynamic effects and target engagement in clinical studies. Translational Sciences at Isomorphic Labs The Translational Sciences group in Boston is essential to the company’s mission. This team informs critical decisions across the portfolio, guiding projects through various stages of research and development. Close collaboration with other teams ensures that scientific progress benefits from both biological expertise and AI-driven insights. Company background Founded in 2021, Isomorphic Labs (IsoLabs) builds on the breakthroughs of the AlphaFold system. The company brings together drug discovery experts and machine learning specialists to develop predictive and generative AI models that accelerate scientific progress. The team uses AI to model complex biological systems, design new therapeutic molecules, and pursue treatments for challenging diseases. Ongoing innovation in model architecture supports work across diverse therapeutic areas and modalities. Culture Isomorphic Labs values interdisciplinary collaboration and a supportive environment. Every team member contributes to the shared goal of addressing serious diseases through AI-driven science and digital biology.

Join Isomorphic Labs as the Head of Chemistry in Drug Design, where you will be at the forefront of innovative drug discovery. You will lead a talented team of chemists, collaborating with interdisciplinary groups to design and optimize drug candidates. Your expertise will guide the development of cutting-edge pharmaceutical solutions that have the potential to transform patient outcomes.

Role Overview Isomorphic Labs is seeking a Director of Computational Drug Design to join its Cambridge, MA site. This leader will shape computational chemistry strategy for both internal research and collaborative projects. The position sits within the Drug Design and Medical Research division, working closely with AI and machine learning specialists to advance the company’s drug design engine and accelerate new medicine development. About Isomorphic Labs Founded in 2021, Isomorphic Labs (IsoLabs) builds on the AlphaFold system, applying advanced AI to solve complex problems in human health. The team combines drug discovery expertise with machine learning to create predictive and generative models that speed up scientific discovery. The company’s mission is to design novel molecules, predict drug performance, and develop new treatments for challenging diseases by modeling biological systems with AI. Isomorphic Labs has developed an AI-driven drug design engine capable across various therapeutic areas and drug types. The organization continues to refine model architectures and expand capabilities, aiming to realize the promise of digital biology and ultimately eradicate disease through artificial intelligence. About the Computational Drug Design Team The Cambridge-based Computational Drug Design team brings together computational chemists focused on driving strategy, supporting both internal and partner projects. Close collaboration with AI/ML colleagues is central to the group’s work, ensuring the continued evolution of the Isomorphic Labs Drug Design Engine. The team values a supportive environment, ongoing learning, and professional development for every member.

As a Drug Safety Associate at Integrated Resources Inc., you will play a crucial role in ensuring the safety and efficacy of pharmaceutical products. You will be responsible for monitoring and evaluating adverse events, coordinating safety reports, and contributing to the overall pharmacovigilance efforts within our organization. Your attention to detail and analytical skills will be vital in supporting our commitment to patient safety.

Role overview Lila Sciences seeks a Scientist I/II in Drug Delivery Chemistry for its Cambridge, MA location. This role centers on advancing drug delivery systems that align with the company’s broader research objectives. Key responsibilities Collaborate with fellow researchers to design and refine drug delivery technologies. Apply chemistry expertise to enhance scientific strategies and laboratory processes. Contribute to projects focused on improving patient outcomes through innovative drug delivery solutions. Location This position is based in Cambridge, Massachusetts.

About Healx Healx is an innovative tech bio company harnessing the power of AI to revolutionize drug discovery. With more than 10,000 rare diseases impacting 400 million individuals worldwide, and 90% of these conditions without approved treatments, our mission is to spearhead a new era in drug development that expedites access to therapies for patients. We merge extensive data analytics, cutting-edge artificial intelligence, and deep pharmacological knowledge to create therapies with greater efficiency and cost-effectiveness compared to traditional methods. Diversity and inclusion are fundamental to our mission of supporting those with rare diseases. We believe that cultivating and empowering a diverse workforce is essential to fulfilling this vision. We warmly invite applications from individuals of all backgrounds and experiences. If you are passionate about our mission and values, we encourage you to apply, even if you don’t meet every listed requirement. Our Core Values Care for rare – Our focus is on patients at the center of all we do. Grow as individuals – We are committed to continuous learning and expertise development. Win as a team – We promote inclusivity, celebrate achievements, and learn together. Innovate and deliver – We act swiftly, embrace calculated risks, and maintain high standards. The Role We are in search of a Translational Scientist (DMPK & Safety) to play a pivotal role in translating AI-driven drug predictions into clinical outcomes. This position is drug-focused and highly collaborative, where you will generate and analyze data while shaping the non-clinical pathway to clinical application. You will be part of the pharmacology team, collaborating closely with our technology, curation, and clinical teams to convert computational predictions into promising therapeutic candidates. We seek a candidate with robust DMPK expertise who is eager to broaden their scope into a comprehensive translational role, making strategic contributions throughout the drug discovery lifecycle.

Your Impact at Lila Sciences Lila Sciences is seeking a dynamic and visionary Director of Product, Life Sciences to lead our innovative product strategies. In this pivotal role, reporting directly to the Vice President of Life Science Product, you will be at the forefront of enhancing our therapeutic research and development capabilities, shaping the future of drug discovery, chemical synthesis, and scientific intelligence. What You'll Be Building Steer the strategic direction for developing breakthrough AI solutions in drug discovery, chemical synthesis, and molecular characterization. Convert strategic goals into comprehensive target product profiles (TPPs) and development campaigns that will empower our science and engineering teams to achieve groundbreaking innovations in life sciences. Lead customer and internal-user discovery initiatives, acting as the primary technical liaison between external customers and partners. Pinpoint and cultivate product opportunities driven by real-world discovery challenges, collaborating closely with stakeholders to ensure relevance and maximize downstream value. Transform insights into precise product requirements, acceptance criteria, and experimental plans that will guide our engineering and science teams. Oversee product execution from inception to launch, leading cross-functional teams across various disciplines including science, machine learning, automation, and software engineering. Manage resource allocations effectively (budget, compute, lab access, personnel) against a complex array of priorities. Establish clear success metrics and milestones, communicating progress to the organization, including executive leadership. What You'll Need to Succeed Advanced degree (MS, PhD, or equivalent experience) in medicinal chemistry, chemical biology, chemical engineering, biochemistry, or a related field, with a solid foundation in experimental science. 7+ years of experience in Product Management, particularly in developing new or experimental products in drug discovery, molecular profiling, machine learning, or scientific software development. In-depth understanding of drug development processes, molecular and cellular research tools, as well as wet and dry lab workflows. Experience with small molecule discovery workflows (e.g., lead optimization, ADMET profiling, synthesis planning) is highly preferred.

Join Integrated Resources Inc. as a Senior Drug Safety Associate and contribute to the vital field of drug safety and pharmacovigilance. In this role, you will play a key part in monitoring and ensuring the safety of pharmaceutical products, working closely with cross-functional teams to assess risk and implement safety measures.

Scholar Rock, Inc. is a pioneering biopharmaceutical firm dedicated to the discovery, development, and delivery of transformative therapies for individuals suffering from serious diseases with significant unmet medical needs. As a recognized leader in the biology of the transforming growth factor beta (TGFβ) superfamily of proteins, Scholar Rock is committed to advancing innovative treatments where the modulation of protein growth factors is crucial. Over the last decade, we have developed a robust pipeline aimed at redefining the standard of care for neuromuscular conditions, cardiometabolic disorders, cancer, and other diseases where growth factor-targeted therapies can radically change patient outcomes. Scholar Rock is the first and only company to demonstrate clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). Our commitment to unlocking unique therapeutic strategies is driven by our proprietary platform, which has generated novel monoclonal antibodies designed to modulate protein growth factors with remarkable precision. By leveraging cutting-edge scientific advancements in therapeutic areas that have historically been overlooked by conventional treatments, Scholar Rock tirelessly works to create new avenues for patient care. Discover more about our innovative approach at ScholarRock.com and follow us on @ScholarRock and LinkedIn.Position Overview:The Senior Medical Director of Drug Safety & Pharmacovigilance plays a critical role within the company, significantly influencing the development and lifecycle management of drug projects. This position is responsible for defining and implementing safety strategies and providing expert guidance during both pre- and post-approval phases for assigned products. The Senior Medical Director will proactively lead risk management initiatives in compliance with global regulatory standards, continuously evaluating safety data, conducting signal detection, and managing the safety profiles of compounds. Additionally, this role will involve close collaboration with cross-functional teams to achieve project objectives within established timelines and quality standards.

We are seeking a highly skilled Associate Director of Drug Safety and Pharmacovigilance to join our dynamic team at Nuvalent. This pivotal role involves overseeing drug safety operations, ensuring compliance with regulatory requirements, and enhancing the pharmacovigilance strategy. The ideal candidate will possess a deep understanding of drug safety processes and a passion for advancing patient safety in the pharmaceutical industry.

Join Eurofins Scientific as a Business Development Manager specializing in Drug Discovery. In this dynamic role, you will drive strategic initiatives to enhance our laboratory testing services, fostering collaboration with clients and stakeholders. You will leverage your expertise to identify market opportunities, develop client relationships, and contribute to the growth of our innovative drug discovery solutions.

Your Impact at Lila Sciences We are on the lookout for an innovative and strategic Vice President / Head of Marketing dedicated to driving commercial growth and fostering strategic partnerships. This pivotal role is designed to enhance our sales pipeline, facilitate revenue generation, and boost partner-driven adoption across key industry sectors. The reporting structure is adaptable, allowing for collaboration under our Chief Communication Officer while working directly with our CEO/Founder. You will collaborate daily with teams across Sales, Partnerships, Revenue, Product, and Scientific leadership to define and implement marketing initiatives that translate cutting-edge science and technical capabilities into enterprise-ready solutions that build trust and close deals. What You Will Be Building Drive Commercial Demand and Pipeline Develop and manage a comprehensive demand generation engine targeting senior scientific and business stakeholders, including R&D leadership, innovation executives, and technical decision-makers. Create account-based marketing strategies tailored for enterprise and strategic accounts. Strategically plan and optimize the marketing channel mix, encompassing digital campaigns, field events, executive programs, and partner-driven initiatives. Oversee reporting mechanisms and feedback loops that align marketing efforts with pipeline outcomes. Enable Partnerships and Ecosystem Growth Craft go-to-market strategies with partners aimed at generating qualified introductions and collaborative opportunities. Produce partner-facing collateral, co-marketing materials, and joint event strategies. Identify and nurture ecosystems significant to Lila’s commercial growth, including scientific communities, industry networks, and mission-aligned institutions. Build Segment-Specific Positioning and Sales Enablement Articulate Lila’s technical platform into clear, differentiated value propositions tailored for key verticals. Collaborate with Commercial leadership to define Ideal Customer Profiles (ICPs), buyer personas, and qualification narratives. Deliver sales enablement materials, including pitch narratives, technical documentation, case studies, ROI framing, objection handling, and competitive analysis. Support extended enterprise sales cycles with relevant proof points at each stage. Produce Revenue-Enhancing Content Create impactful content such as technical briefs, case studies, webinars, white papers, and executive narratives. Transform customer and partner success stories into reusable assets that foster trust and expedite decision-making. Ensure that marketing outputs align with Lila’s brand and messaging standards.

Scholar Rock is a pioneering biopharmaceutical organization dedicated to the discovery, development, and provision of transformative therapies aimed at addressing significant unmet medical needs for individuals suffering from serious health conditions. As a frontrunner in understanding the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins, our clinical-stage company is devoted to advancing innovative treatments that leverage the fundamental role of protein growth factors. Over the last decade, we have established a robust pipeline that aims to elevate the standard of care for conditions such as neuromuscular diseases, cardiometabolic disorders, cancer, and other illnesses where growth factor-targeted therapies can make a substantial difference. Scholar Rock is distinctively positioned as the only company to showcase clinical proof of concept for a muscle-targeted therapy in spinal muscular atrophy (SMA). Our unwavering commitment to exploring fundamentally novel therapeutic strategies is fueled by our proprietary platform, which has successfully developed innovative monoclonal antibodies designed to modulate protein growth factors with remarkable selectivity. By applying cutting-edge scientific advancements in traditionally under-addressed disease areas, we strive daily to forge new possibilities for patients. Discover more about our approach at ScholarRock.com and follow us on @ScholarRock and LinkedIn.Position Overview:Scholar Rock is actively seeking a highly skilled and technically adept Senior Director of Drug Product External Manufacturing to spearhead the external manufacturing of drug products across our portfolio of biologics, which includes monoclonal antibodies, fusion proteins, and bispecifics. In this pivotal role, you will lead and supervise all drug product manufacturing operations conducted through external contract manufacturing organizations (CMOs). This position is essential for ensuring the efficient production, quality assurance, and timely delivery of both clinical and commercial products, in alignment with our organizational objectives and stringent regulatory requirements. The ideal candidate will possess extensive expertise in biopharmaceutical manufacturing, demonstrate strategic leadership capabilities, and exhibit a strong aptitude for managing complex global operations.

Nuvalent is seeking a highly experienced and visionary Senior Director of Drug Metabolism and Pharmacokinetics (DMPK) to lead our DMPK team. This role is crucial for the advancement of our drug development programs as we strive to create innovative treatments. Join us in our mission to transform the lives of patients with targeted therapies.

We are seeking an experienced and innovative Device Development Lead to spearhead our efforts in advancing Drug Delivery Systems. The ideal candidate will possess a deep understanding of device development, coupled with a passion for enhancing patient outcomes through cutting-edge technology.Your role will involve leading cross-functional teams, driving product design, and ensuring compliance with regulatory standards. You will also be responsible for conducting feasibility studies, prototyping, and overseeing the entire development lifecycle from concept to clinical trials.

Lila Sciences seeks a Life Science Program Lead based in Cambridge, MA. This position centers on guiding research programs from planning through delivery, with a focus on advancing key initiatives in the life sciences. The role involves close collaboration with teams spanning multiple scientific fields and plays a key part in supporting project success. Main responsibilities Manage project planning and oversee daily execution for life science programs Work alongside multidisciplinary teams to move research initiatives forward Track progress and help ensure programs meet their objectives What we look for Genuine interest in science and research Dedication to maintaining high standards and achieving program goals Background in working with or leading cross-functional teams

Your Contribution at Lila SciencesWe are on the lookout for an innovative and talented Multimedia Specialist to enhance our dynamic team. In this in-house position, you will be the primary resource for design (presentations, overviews, explainers), video production, photography, animation, and multimedia content development.This role is situated within a highly technical environment, and the ideal candidate should feel at ease collaborating with scientific and engineering teams, swiftly grasping new concepts, and translating intricate ideas into visually engaging and impactful narratives. A background in science, biology, AI, robotics, or software will be highly advantageous.In addition to content creation, you will play a crucial role in ensuring our expanding library of visual and multimedia resources are well-organized, archived, and readily reusable across various teams, including Sales Enablement, Commercial, Marketing & Communications, and scientific teams documenting research and lab procedures.Key ResponsibilitiesCore Multimedia ProductionCreate and produce captivating multimedia content, including videos, graphics, and animations, tailored for various platforms.Capture and edit high-quality photographs and videos for promotional materials, internal communications, and social media content.Oversee the entire production process from concept development to final delivery, including light coordination of timelines, reviews, and asset handoff.Stay abreast of industry trends and best practices in multimedia production.Scientific and Technical CommunicationCollaborate with scientific, engineering, and product stakeholders to interpret complex topics and convert them into accurate visual narratives.Create content for both external and internal audiences, such as:Sales enablement and commercial materials (short videos, demo clips, slide visuals, one-pager graphics)Scientific and technical explainers (animations, diagrams, process visuals)Lab/team documentation that captures discoveries and workflowsCollaboration and Visual StorytellingWork closely with Marketing & Communications team members to strategize and execute visual storytelling initiatives across multiple channels.

Your Contribution at Lila Sciences Be a part of innovating the scientific landscape! We are on the lookout for a talented software engineer with a background in life sciences to enhance our data science team. In this role, you will collaborate closely with software engineers, laboratory scientists, and machine learning engineers to develop state-of-the-art tools for automated scientific analysis and beyond. Your expertise in web services and data engineering, particularly in Python development for scientific applications, will be crucial. If you excel in a collaborative and fast-paced environment while adhering to best practices in git, development workflows, and user-centered design, we encourage you to apply! Your Responsibilities Engage in the complete software development life cycle, concentrating on the design, implementation, and maintenance of software services. Create reusable code and libraries to enhance efficiency and scalability. Ensure development aligns with strategic objectives, facilitating software that meets broader organizational requirements. Oversee git repositories, manage the team’s Jira board and Notion Hub, advocate for best practices, assist laboratory scientists in utilizing new tools, and cultivate a collaborative development culture. Collaborate directly with scientists to identify gaps and unmet needs, crafting customized software solutions for data management, LIMS functionality, and data automation. Advocate for infrastructure as code and devise efficient deployment strategies. Produce clear, concise documentation for both engineering teams and end users. Required Qualifications A minimum of 2 years of experience in software development within a commercial environment. High proficiency in Python programming. Solid understanding of git best practices. Strong listening skills and the patience to thoroughly understand user challenges. Experience in implementing scalable software solutions. Exceptional problem-solving abilities and a team-oriented mindset. Excellent communication skills for effective collaboration with team members and stakeholders. A proactive self-starter with independent thinking capabilities and keen attention to detail. Desire to work with highly skilled and dynamic teams in a fast-paced, entrepreneurial technical setting. Preferred Qualifications A background in biological sciences. Familiarity with data science and machine learning libraries (e.g., pandas, numpy, scipy). Knowledge of modern developer tools (e.g., pydantic, pyright, uv). Understanding of Kubernetes, ArgoCD, and GitHub Actions.

Your Contribution at Lila Lila Sciences is in search of a skilled and knowledgeable Technical Science Writer / Content Creator to play a pivotal role in articulating our scientific endeavors. This position resembles that of a managing editor, where you will convert intricate scientific concepts into precise and comprehensible content, while also mentoring a select group of contract writers to maintain exceptional storytelling quality. This role is crucial as impactful science can only transform the world when it is both understood and trusted. Your contributions will assist: Customers in grasping what Lila enables, its functionality, and its reliability. Partners in identifying opportunities for collaboration and understanding effective integration. Government and public-sector partners in evaluating relevance, safety, and societal benefits. Investors in comprehending the technical advantages, platform strategy, and long-term vision. Future employees in recognizing our ambitions, rigorous standards, and the challenges they will tackle. Your Responsibilities Draft and refine high-quality articles, explainers, technical summaries, case studies, and multimedia scripts that convey complex scientific themes with precision and narrative strength. Produce content that links what we are developing to its significance, emphasizing scientific integrity, measurable outcomes, and responsible communication. Targeted Storytelling Customize messaging and formats to meet the diverse needs of stakeholders: Customers: practical results, workflows, reliability, and real-world constraints. Partners: collaborative roadmaps, innovation narratives, and integration stories. Government entities: public benefits, validation, safety, and responsible use. Investors: distinctiveness, defensibility, and platform direction. Candidates: our mission, culture of rigor, and the problems they will address. Develop “layered” content assets, allowing a core story to be adapted across various formats (e.g., social media posts, blogs, technical briefs, presentations). Editorial Leadership Delegate tasks to contract writers, establish clear guidelines, and provide constructive feedback to ensure quality, coherence, and a consistent voice.