Machine Learning Research Scientist in Computational Biophysics

About Scale AI At Scale AI, we are committed to propelling the advancement of AI technologies. For over eight years, we have been a pioneer in the AI data sector, supporting groundbreaking innovations in areas such as generative AI, defense solutions, and autonomous driving. Following our recent Series F funding round, we are enhancing access to premium data to accelerate the journey towards Artificial General Intelligence (AGI). Building on our legacy of model evaluation for both enterprise and governmental clients, we are expanding our capabilities to establish new benchmarks for evaluations in both public and private domains. About This Role This position is at the leading edge of AI research and practical implementation, concentrating on reasoning within large language models (LLMs). The successful candidate will investigate critical data types vital for evolving LLM-based agents, including browser and software engineering agents. You will significantly influence Scale’s data strategy by pinpointing optimal data sources and methodologies to enhance LLM reasoning. To excel in this role, you will require a profound understanding of LLMs, planning algorithms, and fresh approaches to agentic reasoning, alongside inventive solutions to challenges in data generation, model interaction, and evaluation. Your contributions will lead to transformative research on language model reasoning, facilitate collaboration with external researchers, and engage closely with engineering teams to translate cutting-edge advancements into scalable, real-world applications.

Position OverviewAt Sentra, we are pioneering the development of organizational superintelligence through innovative memory infrastructure that intelligently processes time, causality, and context. As a Machine Learning Research Scientist, you will address fundamental challenges in knowledge representation, temporal reasoning, and semantic compression. Your mission will be to design and implement sophisticated systems that preserve the execution state for entire organizations, transforming millions of micro-events into robust knowledge and identifying patterns for predicting future events.Key ResponsibilitiesDevelop LLM-powered information extraction pipelines to convert unstructured communications and textual data into structured entity-relationship models.Create memory consolidation algorithms that validate information through multiple observations, merge duplicate entities, and efficiently prune transient data.Architect temporal knowledge graphs that represent organizational execution states as dynamic, continuously updated frameworks instead of static records.Implement graph attention mechanisms and reasoning systems for intricate causal queries regarding blockers, dependencies, and outcome patterns.Conduct research on lossy semantic compression using information-theoretic principles to distill event streams into query-relevant long-term memory.Design entity resolution systems that effectively manage identity evolution, where entities may merge, split, and transform over time.Construct meta-learning systems that uncover organizational patterns and discern when current situations align with historical indicators of success or failure.Innovate privacy-preserving cross-organizational learning approaches utilizing federated learning and differential privacy techniques.Publish research findings and actively contribute to the wider research community focused on knowledge graphs and organizational intelligence.

About AnthropicAt Anthropic, we are dedicated to developing AI systems that are reliable, interpretable, and steerable. We aim to ensure that AI is safe, beneficial, and aligned with the needs of both our users and society. Our expanding team consists of passionate researchers, engineers, policy experts, and business leaders collaborating to create groundbreaking AI solutions.About the RoleWe are seeking a talented Research Engineer with a solid foundation in computer vision, who shares our belief that visual and spatial reasoning are essential for unleashing the full potential of large language models (LLMs). In this collaborative role, you will engage in research, development, and evaluation of cutting-edge Claude models, with a specific emphasis on enhancing visual and spatial capabilities. You will contribute across multiple facets of our research initiatives, employing a full-stack approach that encompasses pretraining, reinforcement learning (RL), and runtime techniques such as agentic harnesses. Additionally, you will work closely with our product team to ensure that your vision enhancements positively influence Claude's performance in real-world applications.

At Causal Labs, we are on a groundbreaking mission to develop general causal intelligence—artificial intelligence that not only predicts future events but also determines the most effective actions to influence those outcomes.To achieve this monumental goal, we are constructing a Large Physics Foundation Model (LPM). Our focus is on domains governed by physical laws, which inherently exhibit cause-and-effect relationships, setting them apart from traditional visual or textual data.Weather serves as the ideal training environment for our LPM, being one of the most extensively observed physical systems available. It provides immediate, objective feedback from sensory observations and boasts data scales significantly larger than those currently employed to train existing language models.Our team at Causal Labs includes leading researchers and engineers with backgrounds in self-driving technology, drug discovery, and robotics, hailing from prestigious organizations such as Google DeepMind, Cruise, Waymo, Meta, Nabla Bio, and Apple. We firmly believe that achieving general causal intelligence will represent one of the most critical technological advancements for our civilization.We are seeking innovative researchers eager to confront unsolved challenges in the field.This role presents an opportunity to create powerful models rooted in observable feedback and verifiable ground truths. If you possess experience in pioneering research and training large-scale models from the ground up in areas such as language and vision models, robotics, or biology, we invite you to join our mission.

About Our TeamJoin the forefront of AI innovation with the RL and Reasoning team at OpenAI. Our team is dedicated to advancing reinforcement learning research and has pioneered transformative projects, including o1 and o3. We are committed to pushing the limits of generative models while ensuring their scalable deployment.About the RoleAs a Research Engineer/Research Scientist at OpenAI, you will play a pivotal role in enhancing AI alignment and capabilities through state-of-the-art reinforcement learning techniques. Your contributions will be essential in training intelligent, aligned, and versatile agents that power various AI models.We seek individuals with a solid foundation in reinforcement learning research, agile coding skills, and a passion for rapid iteration.This position is located in San Francisco, CA, and follows a hybrid work model of three days in the office per week. We also provide relocation assistance for new hires.You may excel in this role if:You are enthusiastic about being at the cutting edge of RL and language model research.You take initiative, owning ideas and driving them to fruition.You value principled methodologies, conducting simple experiments in controlled environments to draw trustworthy conclusions.You thrive in a fast-paced, complex technical environment where rapid iteration is essential.You are adept at navigating extensive ML codebases to troubleshoot and enhance them.You possess a profound understanding of machine learning and its applications.About OpenAIOpenAI is a pioneering AI research and deployment organization committed to ensuring that general-purpose artificial intelligence serves the greater good for humanity. We strive to push the boundaries of AI system capabilities while prioritizing safe deployment through our innovative products. We recognize AI as a powerful tool that must be developed with safety and human-centric principles, embracing diverse perspectives to reflect the full spectrum of humanity.We are proud to be an equal opportunity employer, welcoming applicants from all backgrounds without discrimination based on race, religion, color, national origin, sex, sexual orientation, age, veteran status, disability, genetic information, or any other legally protected characteristic.

Join Handshake as a Machine Learning Research Scientist and contribute to groundbreaking projects that leverage advanced algorithms and data analysis to drive innovation. In this role, you will collaborate with a dynamic team to design, implement, and evaluate machine learning models that enhance our products and services. Your expertise will be pivotal in unlocking new insights from data, improving user experiences, and shaping the future of our technology.

About Scale AI At Scale AI, we are dedicated to propelling the advancement of AI applications. Over the past eight years, we have established ourselves as the premier AI data foundry, supporting groundbreaking innovations in fields such as generative AI, defense technologies, and autonomous vehicles. Following our recent Series F funding round, we are intensifying our efforts to harness frontier data, paving the way toward achieving Artificial General Intelligence (AGI). Our work with enterprise clients and governments has enhanced our model evaluation capabilities, allowing us to expand our offerings for both public and private evaluations. About the ACE Team The Agent Capabilities & Environments (ACE) team, a vital part of Scale’s Research organization, unites customer-focused Researchers and Applied AI Engineers. Our primary mission is to conduct research on agent environments and reinforcement learning reward signals, benchmark autonomous agent performance in real-world contexts, and develop robust data programs aimed at enhancing the capabilities of Large Language Models (LLMs). We are committed to creating foundational tools and frameworks for evaluating models as agents, focusing on autonomous agents that interact dynamically with a wide range of external environments, including code repositories and GUI interfaces. About This Role This position sits at the cutting edge of AI research and its practical applications, concentrating on the data types necessary for the development of state-of-the-art agents, including browser and software engineering agents. The ideal candidate will investigate the data landscape required to propel intelligent and adaptable AI agents, steering the data strategy at Scale to foster innovation. This role demands not only expertise in LLM agents and planning algorithms but also creative problem-solving skills to tackle novel challenges pertaining to data, interaction, and evaluation. You will contribute to influential research publications on agents, collaborate with customer researchers, and partner with the engineering team to transform these advancements into scalable real-world solutions.

At Scale AI, we collaborate with leading AI laboratories to supply high-quality data and foster advancements in Generative AI research. We seek innovative Research Scientists and Research Engineers with a strong focus on post-training techniques for Large Language Models (LLMs), including Supervised Fine-Tuning (SFT), Reinforcement Learning from Human Feedback (RLHF), and reward modeling. This position emphasizes optimizing data curation and evaluation processes to boost LLM performance across text and multimodal formats. In this pivotal role, you will pioneer new methods to enhance the alignment and generalization of extensive generative models. You will work closely with fellow researchers and engineers to establish best practices in data-driven AI development. Additionally, you will collaborate with top foundation model labs, providing critical technical and strategic insights for the evolution of next-generation generative AI models.

Join us at Physical Intelligence as a Research Scientist, where you will be at the forefront of innovation in machine learning and robotics. We are in search of exceptional researchers across all experience levels who demonstrate a strong track record of impactful research results. Ideal candidates will possess a solid foundation in both practical implementation and theoretical frameworks, showcasing a blend of system-building capabilities and significant conceptual, algorithmic, or theoretical advancements. We value diverse backgrounds and encourage applications from both traditional academic researchers and those with unique, unconventional experiences.We are committed to fostering a diverse and inclusive workplace. In accordance with the San Francisco Fair Chance Ordinance, we welcome applications from qualified individuals with arrest and conviction records.

Zyphra is a pioneering artificial intelligence firm located in the vibrant city of San Francisco, California.About the Role:We are seeking a passionate Research Scientist to join our dynamic Agency and Reasoning Team at Zyphra. In this role, you will conduct cutting-edge research in reinforcement learning, post-training methodologies, and human preference learning. Your innovative ideas will be instrumental in shaping our next-generation language models, enabling their application on a large scale.What We Desire:A strong sense of research intuition and tasteCapability to navigate a research project from initial concept to execution and documentationProficiency in implementation and prototypingA quick thinker who can rapidly transform ideas into experimental frameworksAbility to collaborate effectively in a fast-paced research environmentAn insatiable curiosity and enthusiasm for the study of intelligence.Qualifications:Proven experience and skill in reinforcement learning, particularly in the context of language model reasoning or classical RL tasksFamiliarity with language-model-supervised fine-tuning and preference-learning techniques, such as DPO and simPO.Experience with methods for context-length extensionStrong intuitive understanding of model behaviors, with the ability to refine them through iterative fine-tuningInterest in engaging deeply with data and dedicating time to data engineering and synthetic data generationA postgraduate degree in a scientific discipline (Computer Science, Electrical Engineering, Mathematics, Physics)Published research in reputable machine learning venuesExpertise in PyTorch and PythonEagerness and aptitude for rapidly acquiring new knowledge and implementing innovative conceptsExceptional communication and teamwork abilities, capable of contributing to both research and large-scale engineering effortsWhy Join Zyphra?We champion creative and unconventional ideas and are prepared to invest significantly in innovative concepts.Our culture fosters collaboration, curiosity, and intellectual growth.

Become a Pioneer in Sleep FitnessAt Eight Sleep, we're dedicated to unlocking human potential through optimal sleep. As the world's first sleep fitness company, we are revolutionizing what it means to be well-rested by creating the most advanced hardware, software, and AI technology. Our innovative products enhance mental, physical, and emotional performance by transforming each night into a personalized, data-driven recovery journey. Trusted by high achievers, professional athletes, and health-conscious individuals across over 30 countries, we have been recognized by Fast Company as one of the Most Innovative Companies in 2019, 2022, and 2023, and honored twice by TIME's “Best Inventions of the Year.” Our high-performance team operates with speed, focus, and a commitment to impact. We don't just create; we refine and obsess over every detail to ensure our members sleep better and wake up stronger.Every position at Eight Sleep offers the opportunity to innovate cutting-edge technology, collaborate with exceptional talent, and contribute to a future where sleep is a powerful tool for well-being. If you're ready to break away from the ordinary and eager to build at the forefront of possibility, this is your chance to join us in reshaping how the world sleeps and what we can achieve upon waking.Our Culture: High Standards, No CompromiseOur mission demands intensity, and at Eight Sleep, we embody the mindset of the world's top performers: focused, relentless, and committed to being in the top 1% of our field. Inspired by the relentless drive of legends like Kobe Bryant, we apply that mentality to bold ideas, next-gen technology, and impeccable execution. This is not a standard 9-to-5 role; our team is dedicated, often working 60+ hours per week—not out of obligation, but out of passion. If you thrive under pressure and seek to do the most meaningful work of your career, you'll find a home here. If you prefer an easier path, this position is not for you.Your RoleAs a Machine Learning Research Scientist at Eight Sleep, you will be at the cutting edge of sleep innovation. Your mission will be to leverage innovative technology, minimalistic design, and proven clinical science to personalize and enhance sleep experiences, fundamentally changing how people sleep for the better.Our revolutionary temperature-regulated technology, the Pod, has been recognized as a game changer, enhancing health and happiness by transforming sleep. Join us in making sleep count for more.

About the TeamJoin the innovative Post-Training team at OpenAI, where we focus on refining and elevating pre-trained models for deployment in ChatGPT, our API, and future products. Collaborating closely with various research and product teams, we conduct crucial research that prepares our models for real-world deployment to millions of users, ensuring they are safe, efficient, and reliable.About the RoleAs a Research Engineer / Scientist, you will spearhead the research and development of enhancements to our models. Our work intersects reinforcement learning and product development, aiming to create cutting-edge solutions.We seek passionate individuals with robust machine learning engineering skills and research experience, particularly with innovative and powerful models. The ideal candidate will be driven by a commitment to product-oriented research.This position is located in San Francisco, CA, and follows a hybrid work model requiring three days in the office each week. Relocation assistance is available for new employees.In this role, you will:Lead and execute a research agenda aimed at enhancing model capabilities and performance.Work collaboratively with research and product teams to empower customers to optimize their models.Develop robust evaluation frameworks to monitor and assess modeling advancements.Design, implement, test, and debug code across our research stack.You may excel in this role if you:Possess a deep understanding of machine learning and its applications.Have experience with relevant models and methodologies for evaluating model improvements.Are adept at navigating large ML codebases for debugging purposes.Thrive in a fast-paced and technically intricate environment.About OpenAIOpenAI is a pioneering AI research and deployment organization dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We are committed to pushing the boundaries of AI capabilities while prioritizing safety and human-centric values in our products. Our mission is to embrace diverse perspectives, voices, and experiences that represent the full spectrum of humanity, as we strive for a future where AI is a powerful ally for everyone.

About Wispr FlowAt Wispr Flow, we strive to make device interaction as seamless as conversing with a friend.Wispr Flow has revolutionized voice dictation, now preferred by users over traditional keyboards due to its unparalleled accuracy on the first attempt. Our platform is context-aware, personalized, and effective across all devices, whether desktop or mobile.By 2026, we aim to expand beyond dictation to develop native actions within an agentic framework that comprehends and responds to user needs reliably.Our diverse team comprises AI researchers, designers, growth specialists, and engineers dedicated to reimagining human-computer interaction. We value team members who prioritize open communication, exhibit a user-centric mindset, and pay meticulous attention to detail. Our collaborative environment fosters spirited discussions, truth-seeking, and tangible impact.Having achieved a remarkable 150% revenue growth quarterly for the past year, we have successfully raised $81 million from top-tier venture capitalists and renowned angel investors.

At Scale AI, we are the premier partner for data and evaluation in the rapidly evolving field of artificial intelligence. Our commitment to advancing the assessment and benchmarking of large language models (LLMs) positions us at the forefront of AI innovation. We are dedicated to creating leading-edge LLM evaluation methodologies that set new benchmarks for model performance. Our research teams collaborate with the top AI laboratories in the industry to provide high-quality data, accelerate progress in generative AI research, and inform what excellence looks like in this domain. As a Staff Machine Learning Research Scientist on our LLM Evals team, you will spearhead the creation of novel evaluation methodologies, metrics, and benchmarks to assess the strengths and weaknesses of cutting-edge LLMs. Your work will shape our internal strategies and influence the broader AI research community, making this role essential for establishing best practices in data-driven AI development.

At Scale AI, we are at the forefront of artificial intelligence, driving innovation through our advanced data, infrastructure, and tooling that empower the most sophisticated models worldwide. Our teams thrive at the intersection of pioneering research, extensive engineering, and practical deployment, collaborating with leading labs, enterprises, and government entities to explore the vast potential of Generative AI. As AI technology evolves from static models to dynamic, intelligent systems, Scale AI is dedicated to establishing the essential research foundations, evaluation methodologies, and reinforcement learning infrastructure that will shape this transformative era. Join our high-impact research organization, where you will contribute to advancing large language models, post-training evaluation, and agent-based reinforcement learning environments, influencing the future of AI development and implementation. As the Research Scientist Manager, you will spearhead a distinguished team of research scientists and engineers, define the strategic research roadmap, and oversee projects from initial prototyping to final deployment. You will excel in a fast-paced environment, harmonizing deep technical leadership with effective people management, visionary goal setting, and successful delivery.

About Plaid Plaid builds tools that help developers create new financial products and experiences. Since 2013, Plaid has connected millions of users to over 12,000 financial institutions across the US, Canada, the UK, and Europe. The company partners with organizations like Venmo, SoFi, Fortune 500 firms, and major banks to make linking financial accounts to apps and services easier. Headquarters are in San Francisco, with offices in New York, Washington D.C., London, and Amsterdam. Team: Data Foundation & AI The Data Foundation and AI team designs and maintains the machine learning and AI infrastructure that supports Plaid’s products. This group transforms Plaid’s financial network data into flexible formats used by teams across the company. Responsibilities span the entire system lifecycle: data curation for pretraining, model development, deployment, serving, and monitoring in production. Role Overview: Senior Machine Learning Engineer (Research Scientist) This position focuses on applied research for Plaid’s foundation model. The Senior Research Scientist leads efforts to design model architectures, set pretraining objectives, and implement fine-tuning strategies that work across a range of product needs. The role also involves building and maintaining production machine learning systems, including training pipelines, model serving, feature engineering, and performance monitoring. Key Responsibilities Design model architectures and define pretraining objectives for Plaid’s foundation model Develop and apply fine-tuning methods for diverse product use cases Build and maintain end-to-end machine learning systems, from data pipelines to model serving Engineer features and monitor system performance in production Create evaluation frameworks to measure model quality across multiple tasks and metrics Location This role is based in San Francisco.

Join Our Team at Rad AIAt Rad AI, we are dedicated to transforming the healthcare landscape through the power of artificial intelligence. Established by a radiologist, our innovative AI solutions are revolutionizing the field of radiology, enhancing patient care, alleviating clinician burnout, and significantly reducing the time required for report generation. With access to one of the largest proprietary datasets of radiology reports globally, our AI technologies have facilitated the discovery of numerous new cancer diagnoses and halved error rates across tens of millions of reports.Having raised over $140 million in funding, including a highly successful Series C round of $68 million led by Transformation Capital, we are now valued at $528 million. Our prestigious investors, such as Khosla Ventures, World Innovation Lab, Gradient Ventures, and Cone Health Ventures, are all committed to supporting our mission to empower healthcare professionals with cutting-edge AI tools.Our latest breakthroughs in generative AI are utilized by thousands of radiologists every day, supporting nearly half of all medical imaging across the United States, in partnership with esteemed healthcare organizations like Cone Health, Jefferson Einstein Health, Geisinger, Guthrie Healthcare System, and Henry Ford Health.Recognized as one of the most promising healthcare AI companies by CB Insights and AuntMinnie, and ranked as the 19th fastest-growing company in North America by Deloitte, we are committed to creating AI-powered solutions that make a real difference. Recently, Rad AI was also featured on CNBC’s Disruptor 50 list, showcasing the innovation and momentum behind our mission.If you are eager to impact the future of healthcare positively, we would be thrilled to have you join our talented team!Why You Should Join UsWe are seeking a Staff Machine Learning Research Scientist to define and lead Rad AI's next wave of applied research in Natural Language Processing (NLP) and clinical AI. You will engage with large language models, retrieval systems, representation learning, speech processing, and multimodal modeling, prioritizing evaluation and reliability alongside achieving state-of-the-art outcomes. This role offers you the chance to take ownership of projects and establish a direct pathway from research to product implementation.As part of our team, you will work closely with clinicians, engineers, and product leaders to translate foundational research into practical applications that enhance healthcare delivery.

Why Join Achira?Become part of an elite team comprising scientists, machine learning researchers, and engineers dedicated to transforming the predictability of the physical microcosm and revolutionizing drug discovery.Explore uncharted territories: we are on a mission to innovate next-generation model architectures that merge AI with chemistry.Engage in large-scale operations: harness massive computational resources, extensive datasets, and ambitious objectives.Take ownership of significant projects from inception to deployment on large-scale infrastructures.Thrive in a culture that values precision, speed, execution, and a proactive mindset.About the PositionAt Achira, we are committed to developing state-of-the-art foundation models that tackle the most complex challenges in simulation for drug discovery and beyond. Our atomistic foundation simulation models (FSMs) serve as world models of the physical microcosm, incorporating machine learning interaction potentials (MLIPs), neural network potentials (NNPs), and various generative models.We are seeking a Machine Learning Research Engineer (MLRE) who excels at the intersection of advanced machine learning and rigorous research methodologies. Collaborate closely with our research scientists to design and enhance intelligent training systems that propel us beyond contemporary architectures into a new era of ML-driven molecular modeling.Your mission is clear yet ambitious: to establish the foundational frameworks for training atomistic simulation models at scale. This entails a deep dive into architecture, data, optimizers, losses, training metrics, and representation learning, all while constructing high-performance systems that maximize the potential of our models. In this role, you will be instrumental in creating a blueprint for pretraining FSMs similar to today’s large-scale generative AI systems, making a significant impact on drug discovery.At Achira, you will have the chance to pioneer models that comprehend and simulate the physical world at an atomic level, achieving unprecedented speed and accuracy.

About Our TeamJoin the Foundations Research team, where we tackle ambitious and innovative projects that could redefine the future of AI. Our mission is to enhance the science behind our training and scaling initiatives, focusing on pioneering frontier models. We are dedicated to advancing data utilization, scaling methodologies, optimization strategies, model architectures, and efficiency enhancements to accelerate our scientific breakthroughs.About the PositionWe are on the lookout for a dynamic technical research lead to spearhead our embeddings-focused retrieval initiatives. You will oversee a talented team of research scientists and engineers committed to developing foundational technologies that enable models to access and utilize the right information precisely when needed. This includes crafting innovative embedding training objectives, architecting scalable vector storage, and implementing adaptive indexing techniques.This pivotal role will contribute to various OpenAI products and internal research initiatives, offering opportunities for scientific publication and significant technical influence.This position is located in San Francisco, CA, where we embrace a hybrid work model, requiring three days in the office weekly, and we provide relocation assistance for new hires.Your ResponsibilitiesLead cutting-edge research on embedding models and retrieval systems optimized for grounding, relevance, and adaptive reasoning.Supervise a team of researchers and engineers in building an end-to-end infrastructure for training, evaluating, and integrating embeddings into advanced models.Drive advancements in dense, sparse, and hybrid representation techniques, metric learning, and retrieval systems.Work collaboratively with Pretraining, Inference, and other Research teams to seamlessly integrate retrieval throughout the model lifecycle.Contribute to OpenAI's ambitious vision of developing AI systems with robust memory and knowledge access capabilities rooted in learned representations.You Will Excel in This Role If You PossessA proven track record of leading high-performance teams of researchers or engineers within ML infrastructure or foundational research.In-depth technical knowledge in representation learning, embedding models, or vector retrieval systems.Familiarity with transformer-based large language models and their interaction with embedding spaces and objectives.Research experience in areas such as contrastive learning and retrieval-augmented generation.