Lead Software Engineer for Distributed Systems

Join Our Mission to Protect Humanity!Vaxcyte is at the forefront of clinical-stage vaccine innovation, developing high-fidelity vaccines aimed at safeguarding humanity from the dire consequences of bacterial diseases. Our mission tackles serious health challenges, including invasive pneumococcal disease, Group A Strep, and Shigella. As we strive to eradicate or treat these infections, our path to success is clearly defined, and Vaxcyte is poised for long-term achievement. Our Work Ethos: At Vaxcyte, the importance of WHAT we do is matched only by HOW we do it. Our collaborative efforts are guided by four enduring core values: *Rethink Convention: We embrace creative and intellectual diversity to innovate and continuously improve the delivery of vaccines. *Aim High: Our audacious goal is to develop the most complex biologics ever attempted for the protection of humankind. *Lead with Heart: Kindness and inclusivity shape our collaborative and vigorous discussions, advancing our business objectives. *Model Excellence: Our commitment to integrity, accountability, equality, and clarity is vital to overcoming the challenges we face.

Join Our Mission to Safeguard Humanity!Vaxcyte is at the forefront of vaccine innovation, dedicated to developing high-fidelity vaccines that protect against bacterial diseases, which can have severe health implications if left untreated. Our mission to combat bacterial infections like invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning of our journey. With a clear strategy for success, Vaxcyte is well-equipped to achieve meaningful outcomes. Our Approach: The way we work is as important as our mission! We are guided by four core values: *RETHINK CONVENTION: We embrace creative and diverse perspectives in our pursuit of innovative vaccine delivery methods. *AIM HIGH: We strive to achieve groundbreaking goals in the development of complex biologics that protect humanity. *LEAD WITH HEART: Collaboration and constructive debate are at the heart of our inclusive workplace, driving our business objectives forward. *MODEL EXCELLENCE: Our commitment to integrity, accountability, and clarity in communication is vital as we tackle significant challenges.Position Overview:As Vaxcyte embarks on a transformative journey to implement SAP S/4HANA in support of our rapid growth and transition to Commercial Operations, the IT SAP Supply Chain Senior Business Systems Analyst (BSA) will serve as a vital link between the Supply Chain and IT departments. This role is crucial for the successful implementation, stabilization, and continual optimization of the SAP S/4HANA Supply Chain functionalities. Candidates should possess substantial expertise in SAP Supply Chain processes, a robust understanding of contract manufacturing, and experience managing complex ERP implementation projects.Key Responsibilities:Facilitate the implementation and stabilization of SAP S/4HANA Supply Chain modules within a regulated environment.Collaborate with Supply Chain, Manufacturing, Quality, and IT teams to design future-state processes that align with Vaxcyte's CDMO business model.Assist in data mapping, migration, cleansing, and validation during cutover and post-go-live activities.Demonstrate in-depth knowledge of SAP S/4HANA systems and integration capabilities.

Senior Workplace Platforms Lead, IT & Business SystemsSan Carlos, CA (on-site)About 1XAt 1X, we are pioneering the development of humanoid robots that collaborate with humans to address labor shortages and foster an environment of abundance.The RoleAs the Senior Workplace Platforms Lead, you will be responsible for overseeing and enhancing our collaboration and knowledge management systems, ensuring that teams are aligned, information is accessible, and our tools remain user-friendly as we continue to scale. You will architect scalable information structures, enhance signal clarity across platforms, and implement robust governance standards. This hands-on senior position includes configuring, automating, and continuously refining Slack, Jira, Confluence, and Notion, directly contributing to improved productivity and clarity within the organization.Your ResponsibilitiesManage workplace platforms comprehensively, including Slack, Jira, Confluence, and Notion.Design and uphold scalable information architecture comprising spaces, projects, permissions, templates, and naming conventions.Enhance the Slack experience through strategic channel management, workflows, automation, and retention policies.Standardize and enhance Jira workflows, hygiene practices, and reporting to promote consistency across teams.Establish and maintain a dependable knowledge management system with documentation standards, ownership frameworks, and content lifecycle processes.Minimize tool sprawl by defining clear defaults, integrating systems where beneficial, and consolidating redundant workflows.Implement role-based permissions and ensure reliable access provisioning and offboarding procedures.Directly configure, migrate, troubleshoot, and implement platform upgrades independently, without reliance on external consultants.

Join Our Mission to Safeguard Humanity!Vaxcyte is at the forefront of clinical-stage vaccine innovation, dedicated to engineering high-fidelity vaccines that shield humanity from the dire health implications of bacterial diseases. Our commitment goes beyond developing solutions for serious infections such as invasive pneumococcal disease, Group A Strep, and Shigella. We have a clear and well-defined roadmap for success, positioning Vaxcyte to make a lasting impact. What we accomplish is equally as important as How we achieve it! Our collaborative efforts are grounded in four core values: *RETHINK CONVENTION: We embrace creative and intellectual diversity to innovate and enhance vaccine delivery. *AIM HIGH: We strive to achieve our ambitious objective of developing the most complex biologics to protect humanity. *LEAD WITH HEART: At Vaxcyte, everyone is empowered to lead with kindness, fostering an inclusive environment for collaboration and constructive debate that drives our business goals. *MODEL EXCELLENCE: Our significant challenges demand a collective commitment to integrity, accountability, equality, and clear communication in our decision-making processes.Summary:The Senior Computer Systems Validation (CSV) Engineer will spearhead validation initiatives for cloud-based GxP systems, ensuring compliance with regulatory, quality, and operational standards throughout the system lifecycle. This role emphasizes traditional Computer System Validation while incorporating risk-based Computer Software Assurance (CSA) principles as needed.The successful candidate will collaborate closely with IT and Quality teams to validate and sustain GxP systems across their lifecycle. A strong background in validating relational databases, cloud infrastructure, and integrated applications within regulated biotech or pharmaceutical settings is essential.This is a hands-on role that involves authoring and executing validation documents and protocols for GAMP 5 systems.This position is hybrid, requiring a minimum of three days on-site at our San Carlos, CA location.

Join 1X as a Senior Firmware Engineer specializing in Battery Charging Systems.At 1X, an innovative AI and robotics company based in Palo Alto, California, our goal is to create a more abundant society through versatile robots that can autonomously perform a variety of tasks. We are committed to developing friendly humanoid robots that learn and adapt alongside humans, seamlessly integrating into daily life.We seek passionate, inquisitive individuals eager to shape the future of robotics and AI. If our mission resonates with you, we would love to discuss how your expertise can contribute to our journey.Role OverviewAs a Senior Firmware Engineer, you will play a critical role in designing and maintaining the firmware for our humanoid robot's battery charging system. Your responsibilities will encompass developing the embedded software that governs AC-DC power conversion, charge profile management, and the interface between the charger and the battery management system. You will collaborate closely with hardware architects, electrical engineers, systems engineers, and test engineers to ensure the firmware effectively aligns hardware capabilities with higher-level system requirements, both for prototypes and in production.The charger you will work with is integral to the user experience, requiring compliance with regulatory emissions standards and safe operation in domestic environments. You will manage the charging cycles of a high-energy lithium-ion battery pack, ensuring optimal performance under demanding discharge profiles. Your expertise in power conversion principles and control loop fundamentals will enable you to write resilient firmware that withstands component variations and fault conditions. You will also assess the interactions between charger behavior, battery chemistry, and electromagnetic compatibility (EMC) performance.ResponsibilitiesDevelop and maintain firmware for battery charging systems.Collaborate with cross-functional teams to ensure cohesive design and implementation.Conduct testing and troubleshooting to enhance system reliability.

Join Our Mission to Protect Humankind!Vaxcyte is an innovative clinical-stage vaccine company dedicated to engineering high-fidelity vaccines aimed at safeguarding humanity from the devastating impacts of bacterial diseases. Our mission involves not just the eradication but also the treatment of bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella. We have a clear and ambitious roadmap to success, and Vaxcyte is poised to achieve remarkable milestones. What we do is equally important as how we do it! Our collaborative efforts are anchored by four enduring core values: *RETHINK CONVENTION: We foster creative and intellectual diversity in every aspect of our work, continually innovating how vaccines are delivered. *AIM HIGH: We embody our ambitious goal to courageously create the most complex biologics ever developed for the protection of humankind. *LEAD WITH HEART: At Vaxcyte, every individual leads with a kindness-first and inclusive approach to collaboration, encouraging healthy debate that advances our objectives. *MODEL EXCELLENCE: The scale of our challenges necessitates a shared commitment to integrity, accountability, equality, and clarity in communication and decision-making.Position Summary:Vaxcyte offers an exciting opportunity for a Senior Manager, Quality Control Data Analyst to join our Quality Control (QC) organization. This role will serve as a vital link between our technical QC Operations team and Business teams. The successful candidate will be responsible for the systematic collection, evaluation, interpretation, and visualization of complex datasets, transforming them into actionable insights that inform both technical and business decisions. Key responsibilities include generating reports, managing databases, and utilizing analytical tools to identify trends, initiate quality events when necessary, enhance operational efficiency, and support the formulation of acceptance criteria as well as strategic planning.Essential Functions:Collaborate closely with analytical sub-teams and other departments within Analytics, Process Development, Quality Assurance, Operations, and Regulatory functions.Ensure data integrity, accuracy, and reliability, ensuring datasets are evaluated promptly and conform to quality and regulatory standards, thereby securing a continuous supply of Vaxcyte’s innovative therapies.

Join Our Team as a Safety Systems Engineer!At Robust AI, we are a dynamic and innovative startup founded in 2019, comprised of an exceptional team of experts in robotics, artificial intelligence, and business. Our mission is to revolutionize the robotics industry by developing intelligent, collaborative, and safe robotic systems. As a Safety Systems Engineer, you will play a crucial role in shaping the safety and compliance framework for our cutting-edge warehouse robotic systems. Collaborating closely with our engineering team, you will lead safety testing, implement design modifications, and liaise with external testing organizations. We are looking for adaptable team players who thrive in a fast-paced startup environment and are passionate about advancing the fields of robotics and AI. The base salary for this position ranges from $170,000 to $200,000, based on your qualifications and experience.

Join our dynamic team at Artech Information Systems LLC as a Senior Research Associate. In this role, you will be responsible for conducting in-depth research, analyzing data trends, and presenting findings to drive strategic decision-making. You will collaborate with cross-functional teams to support ongoing projects and contribute to innovative solutions within the organization.

Join Our Team as a C++ Systems Engineer!Location: San Carlos, CA (On-site)About the RoleAt NEO, we are at the forefront of robotics with our humanoid robot that learns from video and interacts seamlessly with people in their homes. We are looking for talented engineers who can enhance the efficiency and intelligence of our robot's brain and nervous system.As a C++ Systems Engineer, you will be responsible for developing the core infrastructure that powers our robotics systems. This includes building robust sensor pipelines, motor control loops, and inter-process communications that enable our robots to operate effectively in real-world environments.Your Responsibilities Will Include:Designing and implementing low-latency, high-throughput systems using modern C++ that perform reliably on resource-constrained devices.Managing critical real-time infrastructure such as sensor fusion pipelines, motor control interfaces, and foundational libraries utilized across all robots.Constructing IPC and serialization layers to connect perception, planning, and actuation, ensuring efficient data flow through lock-free queues, memory pools, shared-memory buffers, and precise logging systems.Establishing performance benchmarks as the standard reference through microbenchmarks, flamegraphs, and regression tracking to maintain system integrity under load.Resolving complex issues across multiple system layers, including toolchain and ABI problems, linking issues, kernel interfaces, and performance on target hardware.Ensuring system reliability with predictable behavior, clear failure modes, and well-defined interfaces that facilitate collaboration with other teams.Delivering code that is deployed on thousands of robots operating in homes and warehouses, moving beyond mere prototypes.Ideal Candidates Will Possess:A minimum of 5 years of experience in delivering production-grade C++ within performance-critical environments such as robotics, autonomous vehicles, high-frequency trading, game engines, or operating systems.A strong understanding of cycles, cache lines, and performance budgets, designing systems that remain efficient under load.Proficiency in Unix/Linux environments, including command line usage, GNU tools, and Unix philosophy.Experience shipping real-time systems where failure could have significant consequences.Ability to debug at the systems level using benchmarking, profiling, tracing, and assembly code inspection alongside extensive use of Linux kernel interfaces.A knack for writing clear and maintainable code that other engineers can build upon, emphasizing clear interfaces and minimal dependencies.

About Obvio AIEvery year, over 7,500 pedestrians lose their lives due to vehicular accidents in the U.S., a staggering increase of 70% in the last decade. Despite the heightened awareness surrounding road safety, cities are still grappling with the challenge of mitigating hazardous driving behaviors. Current 'Vision Zero' initiatives are not achieving the desired outcomes.Obvio AI is on a mission to transform this narrative.We introduce solar-powered, AI-driven cameras designed to enforce traffic regulations in areas where pedestrians face the highest risk. By automating enforcement methods that surpass traditional systems, we have already made significant strides in reducing reckless driving, enhancing safety for pedestrians, motorists, and law enforcement personnel alike.Founded by the innovators behind Motive’s AI dashcam, Obvio is supported by prominent investors such as Bain Capital Ventures and Khosla Ventures. With a recent $22M Series A funding round and collaborations with some of the nation's most progressive cities, we are poised to create a safer urban landscape globally.About the RoleWe are looking for a Senior Embedded Engineer to spearhead the design and optimization of software that fuels our AI-enhanced traffic monitoring cameras. These systems function in challenging outdoor settings, requiring real-time video processing while adhering to strict power and performance limitations. You will lead architectural decisions, mentor fellow engineers, and collaborate with hardware, AI, and backend teams to develop dependable, efficient embedded systems that accurately identify violations and relay essential data seamlessly.What You’ll DoLead the embedded software architecture for AI camera systems, creating scalable solutions for sensor integration, image processing, and real-time inference pipelines.Optimize performance of C++ code for resource-constrained environments, setting standards for the balance of detection accuracy, power consumption, and processing speed.Design and implement robust embedded systems that operate reliably across varying weather conditions and deployment scenarios at scale.Oversee integration strategies with camera sensors, communication modules, and power management systems utilizing standard embedded protocols.Work closely with AI teams to devise and enhance computer vision model deployment on edge hardware.Establish testing frameworks and debugging tools for the validation of embedded systems.

Join Artech Information Systems LLC as a Scientist in San Carlos, where you will engage in innovative research and development projects that shape the future of technology. You will collaborate with a dynamic team of professionals, leveraging cutting-edge methodologies to drive scientific advancements. We seek passionate individuals who thrive in a fast-paced environment and are eager to contribute to impactful solutions.

About 1X 1X, founded in 2015, designs and develops advanced humanoid robots for home use. The company aims to address labor challenges by creating safe, intelligent robots. Every part of each robot, from motor coils to AI, is built in-house, allowing for full control over quality and innovation. The team values technical excellence and recognizes individual contributions. Role Overview: Senior Materials Lab Engineer 1X seeks a Senior Materials Lab Engineer to drive materials innovation for humanoid robotics in San Carlos, California. This role focuses on polymer-based systems, surface science, adhesives, and coatings. The engineer will play a key part in shaping the materials lab and ensuring high standards in both process and results. What You Will Do Independently manage the formulation, processing, surface treatment, bonding, and testing of advanced materials Oversee daily operations and capabilities of the materials lab Establish and maintain lab protocols for rapid prototyping and validation of components Support the transition from raw materials to finished, validated parts used in humanoid robots What We Look For Extensive experience with polymer-based systems, surface science, adhesives, and coatings Strong hands-on skills and attention to detail Ability to work independently and take ownership of lab operations Experience in setting up and running a high-performance materials lab is a plus This position offers the chance to lead impactful projects and contribute directly to the next generation of robotics.

Vaxcyte, Inc. seeks a Manager of Quality Management System (QMS) Vendor Management & Supplier Notifications to lead supplier-related quality activities. Based in San Carlos, California, this position plays a key role in maintaining and improving supplier compliance within Vaxcyte’s QMS, with a focus on timely and accurate handling of supplier notifications. Role overview This manager oversees the intake, triage, and coordination of supplier notifications using Veeva QMS. The role requires close collaboration across departments to evaluate risks, support change controls, and ensure that supplier compliance standards are met. Responsibilities also include participating in vendor qualification, supplier management, and assisting with audits when needed. Main responsibilities Supplier notification management: Manage the full process for supplier notifications in Veeva QMS, from intake and triage to prioritization and tracking. Conduct initial reviews of supplier notifications to determine necessary actions and assess potential impacts. Coordinate with cross-functional teams to ensure thorough impact assessments and follow-up steps are completed. Collaboration and compliance This position works with teams across the company to evaluate supplier-related risks and support ongoing supplier management. The manager may also contribute to internal and external audits as required.

Join Our Innovative Team as a Robot Systems Engineer!At Robust AI, a dynamic and rapidly expanding startup established in 2019, we are on a mission to revolutionize robotics and artificial intelligence. Our team comprises seasoned professionals from diverse backgrounds, all united by a shared passion for innovation in robotics. If you're eager to help shape the future of autonomous robots that are intelligent, collaborative, and secure, we want to hear from you!As a Robot Systems Engineer, you will be an integral part of our agile team, driving the design and deployment of cutting-edge warehouse robotic systems. You will closely collaborate with our engineering team to enhance Linux-based software platforms that interface with robotic hardware, ensuring optimal real-time control and communication. Your curiosity, expertise, and organizational skills will thrive in our fast-paced startup environment where adaptability is key.Our robots operate in various customer settings and adapt to multiple software and hardware configurations, utilizing onboard, on-premises, and cloud-based systems. Your role will also be pivotal in maintaining the security and integrity of sensitive data both on-robot and off. We offer competitive compensation reflective of your skills and experience.

Join Our Mission at Obvio AIEvery year, over 7,500 pedestrians lose their lives due to vehicular accidents in the U.S., a staggering increase of 70% in the last decade. While awareness is on the rise, many cities continue to grapple with the challenge of reducing dangerous driving. Nationwide efforts like 'Vision Zero' are proving insufficient.At Obvio AI, we strive to change this narrative.We utilize solar-powered, AI-driven cameras to enforce traffic regulations in areas where pedestrians are especially at risk, automating processes in ways that traditional policing methods cannot. Our innovative solutions have significantly curtailed reckless driving, enhancing safety for pedestrians, drivers, and law enforcement alike.Founded by the creators of Motive’s AI dashcam, Obvio is supported by renowned investors such as Bain Capital Ventures and Khosla Ventures. With a recent $22 million Series A funding round, we are collaborating with some of the most progressive cities in the U.S. As we expand to meet a growing market need, we are building a global intelligence framework for safer streets.

About 1X 1X is an AI and robotics company based in Palo Alto, California. The team focuses on building general-purpose robots that support human productivity and autonomy in everyday tasks. Their goal is to develop humanoid robots that learn from people and fit naturally into daily life at home. Who 1X Looks For 1X values curiosity, motivation, and a genuine interest in shaping the future of robotics and AI. The company welcomes those who want to contribute to this mission. Role Overview: Senior to Staff Mechanical Engineer This position is based in San Carlos, California. The Senior to Staff Mechanical Engineer will design, prototype, and deliver electromechanical systems for the Neo robot. This includes responsibility for subsystems throughout their lifecycle: from initial concept and detailed design to testing, iteration, and scaling up for production. The work directly supports the robot’s ability to move, grasp, and operate reliably over time.

About 1XAt 1X, we are pioneers in AI and robotics, headquartered in Palo Alto, California. Our mission is to cultivate a future of abundance through the development of general-purpose robots that can autonomously perform a wide array of tasks.We are dedicated to creating humanoid robots that learn and adapt by living alongside humans, seamlessly integrating into everyday life. Our vision is to foster a collaborative relationship between humans and robots, leading to a smarter, more capable society.We seek innovative, motivated, and passionate individuals eager to influence the future of robotics and AI. If our mission resonates with you, we would love to connect and discuss how you can be a part of our transformative journey.Role OverviewWe are in search of a skilled Firmware / Embedded Engineer to spearhead the development and maintenance of low-level firmware that underpins our system-level hardware architecture. This role will emphasize the creation of robust, maintainable, and well-structured embedded software that spans various hardware domains and directly influences architectural decisions.You will collaborate closely with hardware architects, electrical engineers, systems engineers, and test engineers to ensure that firmware effectively connects hardware capabilities with higher-level system requirements across both prototype and production platforms.Our humanoid robot features over 20 distributed embedded nodes that must communicate deterministically, operate fail-safely, and function continuously in uncontrolled environments. This role represents a new frontier in product development where conventional playbooks are a starting point; however, many encountered challenges require innovative solutions. The ideal candidate will excel in reasoning from first principles, comfortably navigating the interface between firmware and hardware, and will be motivated by the pursuit of novel solutions to complex problems.

Role overview Natera seeks a Senior Manager of Research and Development to join the Oncology Product Development team in San Carlos, CA. This leader will oversee the development and optimization of next-generation sequencing (NGS)-based oncology diagnostic assays. The role also includes supporting product lifecycle management after launch. Success depends on technical leadership, strong collaboration across teams, and attention to product performance and scalability. What you will do Direct the technical development of NGS-based oncology assays, including project planning, execution, and coordination with multiple teams. Lead assay development from feasibility through verification and validation within a regulated CLIA environment. Work in partnership with Research, Informatics, Statistics, Software, Regulatory, Quality, and Commercial teams to bring products from concept to launch. Support post-launch activities such as process improvements, troubleshooting, and collaboration with Operations on commercialized assays. Prepare and review technical documents, including study protocols, reports, and validation materials to meet regulatory and product requirements. Mentor and manage team members, fostering their professional growth. Lead and oversee data analysis using statistical methods. Requirements PhD in Molecular Biology or a related field with at least 6 years of relevant industry experience, or BS/MS with a minimum of 8 years in biotech, including at least 2 years in management. Hands-on experience developing NGS-based assays in a regulated setting; CLIA experience preferred. Familiarity with CLIA laboratory workflows and implementing assays in production. Track record of leading projects and collaborating across functions; people management experience is a plus. Experience with high-throughput workflows or automation is beneficial. Knowledge and skills Strong technical background in oncology diagnostics and NGS technologies. Analytical thinking and problem-solving abilities. Proficiency in technical writing and documentation for regulated environments. Understanding of regulatory standards and design control processes, including LDT, CAP/CLIA, product development lifecycle, and change management. Excellent collaboration, communication, and interpersonal skills.

We are seeking a highly skilled Senior Scientist to join our Research and Development team at Natera in San Carlos, California. In this pivotal role, you will lead innovative projects that contribute to groundbreaking advancements in genetic testing and diagnostics. You will collaborate with cross-functional teams, driving research initiatives that enhance our product offerings and improve patient outcomes.