About the job
About Flagship Pioneering
Flagship Pioneering is a biotechnology company based in Cambridge, MA. The team invents and builds platform companies focused on advancing human health and sustainability. Flagship brings together scientific leaders, entrepreneurs, and experienced capital managers to address challenges ranging from cancer care to sustainable agriculture. The company’s portfolio includes organizations that have vaccinated billions, developed new treatments, and promoted eco-friendly practices.
Flagship has been recognized on FORTUNE’s “Change the World” list and featured in Fast Company’s annual “World’s Most Innovative Companies.”
Role Overview: Lead Cloud Security and Application Security Engineer
This role shapes Flagship’s cloud security and application security engineering practice. Supported by the CISO and Director of Security Engineering, the position focuses on defining and executing cloud posture management, secure software development lifecycle (SSDLC) security, and cloud-side data loss prevention. The engineer will work closely with the Infrastructure & Operations team on cloud architecture and network infrastructure.
One of the main responsibilities is to build workflows that use AI and large language models (LLMs) to automate routine security tasks, freeing up time for complex challenges that require human judgment. The position leads technical execution for cloud security and application security across Flagship and its portfolio, partnering with engineering teams to embed security into development pipelines from the start.
Key Responsibilities
- Establish and lead Flagship’s cloud security and application security engineering practice
- Define cloud posture management, SSDLC security, and cloud-side DLP strategies
- Collaborate with Infrastructure & Operations on cloud architecture and network infrastructure
- Develop and implement AI-enhanced workflows using LLMs and intelligent tools
- Automate recurring tasks to focus on high-impact security work
- Work directly with engineering teams to integrate security into development pipelines
- Drive technical execution of cloud security and AppSec across Flagship and its portfolio companies
Work Location
Cambridge, MA, USA

