About the job
Eikon Therapeutics is a pioneering biopharmaceutical company that leverages innovative technology at the confluence of chemistry, engineering, computation, and biology to create groundbreaking treatments for life-threatening diseases. Our discovery platform is founded on transformative innovations from our Nobel Prize-winning founders (2014), leading to the development of advanced microscopes capable of real-time, molecular-resolution measurements of protein movement in living cells, thus revealing previously inaccessible classes of proteins as potential drug targets.
Position
We are excited to invite an accomplished and proactive Associate Director of Clinical Pharmacology to join our dynamic Clinical Research & Development team. This role will be pivotal in advancing Modeling and Simulation within the Clinical Pharmacology group. Responsibilities will encompass non-compartmental analysis (NCA), population pharmacokinetics/pharmacodynamics (PK/PD), disease progression modeling, statistical and physiologically-based PK (PBPK) modeling, allometric scaling, quantitative systems pharmacology (QSP), clinical trial simulations, literature meta-analysis, machine learning, and other cutting-edge quantitative techniques. The selected candidate will collaborate closely with Clinical Pharmacology Project Leads to utilize quantitative strategies to elucidate the relationship between drug exposure and therapeutic response, facilitating the selection and justification of first-in-human doses, recommended Phase II doses (RP2D), and labeled dosing during regulatory discussions. This position necessitates a minimum of three days a week onsite presence at our Jersey City, NJ location to ensure effective management, operational excellence, and the successful execution of clinical studies, fostering significant team growth and collaboration.

