Head of Chemistry in Drug Design

As a Drug Safety Associate at Integrated Resources Inc., you will play a crucial role in ensuring the safety and efficacy of pharmaceutical products. You will be responsible for monitoring and evaluating adverse events, coordinating safety reports, and contributing to the overall pharmacovigilance efforts within our organization. Your attention to detail and analytical skills will be vital in supporting our commitment to patient safety.

Join Integrated Resources Inc. as a Senior Drug Safety Associate and contribute to the vital field of drug safety and pharmacovigilance. In this role, you will play a key part in monitoring and ensuring the safety of pharmaceutical products, working closely with cross-functional teams to assess risk and implement safety measures.

We are seeking a highly skilled Associate Director of Drug Safety and Pharmacovigilance to join our dynamic team at Nuvalent. This pivotal role involves overseeing drug safety operations, ensuring compliance with regulatory requirements, and enhancing the pharmacovigilance strategy. The ideal candidate will possess a deep understanding of drug safety processes and a passion for advancing patient safety in the pharmaceutical industry.

Scholar Rock, Inc. is a pioneering biopharmaceutical firm dedicated to the discovery, development, and delivery of transformative therapies for individuals suffering from serious diseases with significant unmet medical needs. As a recognized leader in the biology of the transforming growth factor beta (TGFβ) superfamily of proteins, Scholar Rock is committed to advancing innovative treatments where the modulation of protein growth factors is crucial. Over the last decade, we have developed a robust pipeline aimed at redefining the standard of care for neuromuscular conditions, cardiometabolic disorders, cancer, and other diseases where growth factor-targeted therapies can radically change patient outcomes. Scholar Rock is the first and only company to demonstrate clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). Our commitment to unlocking unique therapeutic strategies is driven by our proprietary platform, which has generated novel monoclonal antibodies designed to modulate protein growth factors with remarkable precision. By leveraging cutting-edge scientific advancements in therapeutic areas that have historically been overlooked by conventional treatments, Scholar Rock tirelessly works to create new avenues for patient care. Discover more about our innovative approach at ScholarRock.com and follow us on @ScholarRock and LinkedIn.Position Overview:The Senior Medical Director of Drug Safety & Pharmacovigilance plays a critical role within the company, significantly influencing the development and lifecycle management of drug projects. This position is responsible for defining and implementing safety strategies and providing expert guidance during both pre- and post-approval phases for assigned products. The Senior Medical Director will proactively lead risk management initiatives in compliance with global regulatory standards, continuously evaluating safety data, conducting signal detection, and managing the safety profiles of compounds. Additionally, this role will involve close collaboration with cross-functional teams to achieve project objectives within established timelines and quality standards.

Join Integrated Resources Inc. as a Senior Associate in Pharmacovigilance, where you will play a crucial role in ensuring drug safety and regulatory compliance. We are seeking a detail-oriented professional who is passionate about pharmacovigilance and eager to make a significant impact in the pharmaceutical industry.

Role Overview Isomorphic Labs is seeking a Director of Computational Drug Design to join its Cambridge, MA site. This leader will shape computational chemistry strategy for both internal research and collaborative projects. The position sits within the Drug Design and Medical Research division, working closely with AI and machine learning specialists to advance the company’s drug design engine and accelerate new medicine development. About Isomorphic Labs Founded in 2021, Isomorphic Labs (IsoLabs) builds on the AlphaFold system, applying advanced AI to solve complex problems in human health. The team combines drug discovery expertise with machine learning to create predictive and generative models that speed up scientific discovery. The company’s mission is to design novel molecules, predict drug performance, and develop new treatments for challenging diseases by modeling biological systems with AI. Isomorphic Labs has developed an AI-driven drug design engine capable across various therapeutic areas and drug types. The organization continues to refine model architectures and expand capabilities, aiming to realize the promise of digital biology and ultimately eradicate disease through artificial intelligence. About the Computational Drug Design Team The Cambridge-based Computational Drug Design team brings together computational chemists focused on driving strategy, supporting both internal and partner projects. Close collaboration with AI/ML colleagues is central to the group’s work, ensuring the continued evolution of the Isomorphic Labs Drug Design Engine. The team values a supportive environment, ongoing learning, and professional development for every member.

AbbVie is seeking a highly skilled Associate Director to lead our Safety Operations Portfolio. This pivotal role involves overseeing safety operations while ensuring compliance with regulatory requirements. The ideal candidate will possess exceptional leadership skills and a strong background in pharmacovigilance.Join our dynamic team and contribute to advancing healthcare solutions that enhance patient safety and improve health outcomes. This is an exciting opportunity for professionals looking to make a meaningful impact in the pharmaceutical industry.

About Healx Healx is an innovative tech bio company harnessing the power of AI to revolutionize drug discovery. With more than 10,000 rare diseases impacting 400 million individuals worldwide, and 90% of these conditions without approved treatments, our mission is to spearhead a new era in drug development that expedites access to therapies for patients. We merge extensive data analytics, cutting-edge artificial intelligence, and deep pharmacological knowledge to create therapies with greater efficiency and cost-effectiveness compared to traditional methods. Diversity and inclusion are fundamental to our mission of supporting those with rare diseases. We believe that cultivating and empowering a diverse workforce is essential to fulfilling this vision. We warmly invite applications from individuals of all backgrounds and experiences. If you are passionate about our mission and values, we encourage you to apply, even if you don’t meet every listed requirement. Our Core Values Care for rare – Our focus is on patients at the center of all we do. Grow as individuals – We are committed to continuous learning and expertise development. Win as a team – We promote inclusivity, celebrate achievements, and learn together. Innovate and deliver – We act swiftly, embrace calculated risks, and maintain high standards. The Role We are in search of a Translational Scientist (DMPK & Safety) to play a pivotal role in translating AI-driven drug predictions into clinical outcomes. This position is drug-focused and highly collaborative, where you will generate and analyze data while shaping the non-clinical pathway to clinical application. You will be part of the pharmacology team, collaborating closely with our technology, curation, and clinical teams to convert computational predictions into promising therapeutic candidates. We seek a candidate with robust DMPK expertise who is eager to broaden their scope into a comprehensive translational role, making strategic contributions throughout the drug discovery lifecycle.

Join the Cambridge Boston Alignment InitiativeThe Cambridge Boston Alignment Initiative (CBAI) is a nonprofit organization dedicated to pioneering research and educational initiatives aimed at ensuring a safe and beneficial transition to advanced AI systems. Our mission focuses on producing original research and accelerating AI safety through comprehensive fellowship programs.Since our initial summer fellowship cohort, we have achieved significant milestones, including published papers at prominent conferences such as NeurIPS and ICLR. As we enter 2026, we are poised for rapid growth, planning multiple fellowship cycles and expanding our team significantly.Refer candidates to us, and if hired, you will receive a $5,000 referral bonus!Your RoleAs a Research Program Associate, you will collaborate closely with Research Managers, mentors, and program leadership to design and refine the frameworks that empower fellows to excel in their research. This is a pivotal program-building position where you will create systems for mentor matching, research goal tracking, progress assessment, and problem-solving support for fellows.Program Design & Development (0.6 FTE)Enhance CBAI's fellow selection process and program deliverables.Identify effective outreach channels and manage outreach campaigns for future iterations.Develop evaluation frameworks to assess fellow progress and program effectiveness.Implement structural improvements based on feedback from fellows, mentors, and research managers.Assist in the planning and execution of fellowship events, such as speaker series and poster days.Fellow & Mentor Experience (0.4 FTE)Design and oversee the onboarding process for mentors, ensuring a positive experience.

Join Eurofins Scientific as a Business Development Manager specializing in Drug Discovery. In this dynamic role, you will drive strategic initiatives to enhance our laboratory testing services, fostering collaboration with clients and stakeholders. You will leverage your expertise to identify market opportunities, develop client relationships, and contribute to the growth of our innovative drug discovery solutions.

Isomorphic Labs is hiring a Head of Translational Sciences, Drug Design for its Cambridge, MA site. This senior leader will guide the translational strategy across the drug discovery portfolio, working closely with teams at the intersection of biology, artificial intelligence, and medicine. The position plays a central role in shaping how new therapies are advanced and how disease mechanisms are understood within the organization. Role overview This leadership role focuses on driving translational approaches for drug design. The Head of Translational Sciences will collaborate with colleagues to advance projects from early discovery through clinical evaluation. The team’s work includes strengthening biological insights into disease, supporting the selection of drug targets, and developing biomarkers to track pharmacodynamic effects and target engagement in clinical studies. Translational Sciences at Isomorphic Labs The Translational Sciences group in Boston is essential to the company’s mission. This team informs critical decisions across the portfolio, guiding projects through various stages of research and development. Close collaboration with other teams ensures that scientific progress benefits from both biological expertise and AI-driven insights. Company background Founded in 2021, Isomorphic Labs (IsoLabs) builds on the breakthroughs of the AlphaFold system. The company brings together drug discovery experts and machine learning specialists to develop predictive and generative AI models that accelerate scientific progress. The team uses AI to model complex biological systems, design new therapeutic molecules, and pursue treatments for challenging diseases. Ongoing innovation in model architecture supports work across diverse therapeutic areas and modalities. Culture Isomorphic Labs values interdisciplinary collaboration and a supportive environment. Every team member contributes to the shared goal of addressing serious diseases through AI-driven science and digital biology.

Scholar Rock is a pioneering biopharmaceutical organization dedicated to the discovery, development, and provision of transformative therapies aimed at addressing significant unmet medical needs for individuals suffering from serious health conditions. As a frontrunner in understanding the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins, our clinical-stage company is devoted to advancing innovative treatments that leverage the fundamental role of protein growth factors. Over the last decade, we have established a robust pipeline that aims to elevate the standard of care for conditions such as neuromuscular diseases, cardiometabolic disorders, cancer, and other illnesses where growth factor-targeted therapies can make a substantial difference. Scholar Rock is distinctively positioned as the only company to showcase clinical proof of concept for a muscle-targeted therapy in spinal muscular atrophy (SMA). Our unwavering commitment to exploring fundamentally novel therapeutic strategies is fueled by our proprietary platform, which has successfully developed innovative monoclonal antibodies designed to modulate protein growth factors with remarkable selectivity. By applying cutting-edge scientific advancements in traditionally under-addressed disease areas, we strive daily to forge new possibilities for patients. Discover more about our approach at ScholarRock.com and follow us on @ScholarRock and LinkedIn.Position Overview:Scholar Rock is actively seeking a highly skilled and technically adept Senior Director of Drug Product External Manufacturing to spearhead the external manufacturing of drug products across our portfolio of biologics, which includes monoclonal antibodies, fusion proteins, and bispecifics. In this pivotal role, you will lead and supervise all drug product manufacturing operations conducted through external contract manufacturing organizations (CMOs). This position is essential for ensuring the efficient production, quality assurance, and timely delivery of both clinical and commercial products, in alignment with our organizational objectives and stringent regulatory requirements. The ideal candidate will possess extensive expertise in biopharmaceutical manufacturing, demonstrate strategic leadership capabilities, and exhibit a strong aptitude for managing complex global operations.

Nuvalent is seeking a highly experienced and visionary Senior Director of Drug Metabolism and Pharmacokinetics (DMPK) to lead our DMPK team. This role is crucial for the advancement of our drug development programs as we strive to create innovative treatments. Join us in our mission to transform the lives of patients with targeted therapies.

Role overview Lila Sciences seeks a Scientist I/II in Drug Delivery Chemistry for its Cambridge, MA location. This role centers on advancing drug delivery systems that align with the company’s broader research objectives. Key responsibilities Collaborate with fellow researchers to design and refine drug delivery technologies. Apply chemistry expertise to enhance scientific strategies and laboratory processes. Contribute to projects focused on improving patient outcomes through innovative drug delivery solutions. Location This position is based in Cambridge, Massachusetts.

We are seeking an experienced and innovative Device Development Lead to spearhead our efforts in advancing Drug Delivery Systems. The ideal candidate will possess a deep understanding of device development, coupled with a passion for enhancing patient outcomes through cutting-edge technology.Your role will involve leading cross-functional teams, driving product design, and ensuring compliance with regulatory standards. You will also be responsible for conducting feasibility studies, prototyping, and overseeing the entire development lifecycle from concept to clinical trials.

Join Integrated Resources, Inc. as a Pharmacovigilance Scientist and contribute to the safety and efficacy of pharmaceutical products. In this role, you will be responsible for monitoring, assessing, and reporting adverse effects associated with drug therapies. Your expertise will directly impact patient safety and regulatory compliance while collaborating with cross-functional teams.

Join our team as a Senior Health and Safety Consultant at AECOM in Cambridge. We are looking for an experienced professional who is passionate about promoting health and safety standards across various projects. In this role, you will collaborate with stakeholders to develop and implement safety programs, conduct risk assessments, and ensure compliance with regulations. Your expertise will contribute to creating a safer working environment for all.

Role Overview Lila Sciences seeks an Environmental Health and Safety (EHS) Coordinator (Contractor) to support environmental health, safety, and sustainability programs in laboratory settings. This onsite contract role is based in Cambridge, MA. The position is hands-on, with regular engagement on the lab floor to manage compliance workflows and help build ESG and ISO-compliant programs from the ground up. This role offers the chance to gain practical EHS and laboratory safety experience in a mission-driven scientific environment. The coordinator will also contribute to program development and sustainability reporting. What You Will Do Assist in developing and maintaining EHS programs and policies that meet local, state, and federal regulations, including documenting incidents and tracking corrective actions. Provide ongoing EHS oversight through lab tours, facility walkthroughs, and regular safety inspections. Support biosafety, chemical safety, and hazardous waste management processes, working closely with lab teams to ensure regulatory compliance. Help deliver EHS training and onboarding for new employees and contractors. Contribute to Lila Sciences' ESG program by collecting data, monitoring progress, and preparing sustainability reports and dashboards. Assist with compliance activities for ISO 14001 and ISO 45001, focusing on documentation and process coordination. Participate in developing EHS standards for the AISF blueprint through documentation, policy coordination, and workflow organization. Qualifications Bachelor's degree in Environmental Studies, Environmental Health and Safety, Sustainability, or a related field. 1-3 years of experience in EHS, sustainability coordination, program administration, or a similar area. Strong organizational, communication, and documentation skills. Ability to work independently, manage multiple priorities, and maintain attention to detail. Interest in lab safety, environmental compliance, and sustainability, with a desire to deepen technical EHS knowledge. Familiarity with AI tools is a plus. Preferred Experience Experience with biosafety, chemical hygiene, or hazardous waste handling (from academic, internship, or professional settings). Knowledge of ISO 14001 and/or ISO 45001 standards.

We are open to hiring for this role at various levels of expertise. For the right candidate, this position can be structured as a Senior Research Manager, with compensation tailored to experience and the anticipated scope of work, potentially exceeding the listed pay rate.About the Cambridge Boston Alignment InitiativeThe Cambridge Boston Alignment Initiative (CBAI) is a nonprofit research organization dedicated to promoting research and education aimed at facilitating a safe and beneficial transition to advanced AI systems. Our efforts include generating original research and accelerating AI safety initiatives through our fellowship programs.Our first summer fellowship cohort has already published significant papers at the Mechanistic Interpretability Workshop at NeurIPS and had accepted papers at ICLR. Additionally, some fellows have transitioned to roles at Goodfire and Redwood Research. Following a successful launch in 2025, we are poised for rapid expansion in 2026, with plans to host multiple fellowship cycles (Fall, Spring, and Summer), double our fellowship cohort, and quadruple our team size.Refer candidates to us and earn $5,000 if they are hired.The RoleIn this role, you will collaborate closely with research fellows and their esteemed mentors—renowned researchers from Cambridge and beyond—to support pioneering work on interpretability, AI control, formal verification for provably safe AI, evaluations, and various aspects of AI governance and policy. We are looking for research managers with experience in both technical research and governance and policy research.Research Management Responsibilities (0.7 FTE)Conduct regular one-on-one meetings with fellows to provide constructive feedback on research progress, assist in overcoming challenges, and coach them through issues such as debugging research methodologies and preparing literature scaffolds, as well as supporting data collection, analysis, and methodology development for experiments and hypothesis testing.Offer feedback on fellows' research and help cultivate an environment that encourages rigorous approaches among them.Connect fellows with relevant resources, literature, and opportunities available during and after the fellowship program.Facilitate communication between fellows and their mentors to ensure a supportive research ecosystem.