Senior / Staff Software Engineer - Computational Chemistry & Molecular Dynamics

At Genesis Molecular AI, we are assembling an elite software engineering team dedicated to revolutionizing drug discovery using cutting-edge machine learning, biophysical simulations, and advanced computational chemistry. We seek passionate engineers eager to contribute to the development of innovative medicines while playing a pivotal role in enhancing our software platform.Key ResponsibilitiesDesign, implement, and sustain intricate computational chemistry workflows to facilitate drug discovery processes.Collaborate closely with computational chemists and CADD scientists to operationalize novel computational methodologies for predicting molecular properties.Assist in scaling our data infrastructure to manage billions of data points and execute hundreds of thousands of parallel quantum mechanics and molecular dynamics jobs.Your ProfileA critical thinker who employs first principles reasoning, maintains a balance between meticulous attention to detail and architectural vision, and possesses a strong curiosity to uncover the root causes of challenges.Proficient in navigating all layers of the software stack, creating user-friendly APIs and libraries tailored for computational chemists.Demonstrated experience in computational chemistry and drug discovery.Skilled in writing production-level code and successfully driving projects to fruition.What We ProvideAn opportunity to contribute to high-impact tools and products that are directly utilized to expedite the discovery of new medicines.A collaborative environment with talented colleagues in AI, software engineering, and chemistry, characterized by a blend of intellectual curiosity and humility. Our team engages in weekly discussions of 1-2 recent machine learning or chemistry publications to remain at the forefront of the field and foster creative ideas.Competitive compensation and equity options, along with comprehensive medical, dental, and vision insurance, plus a 401(k) plan.

Join Genesis Molecular AI, where we are assembling an elite software engineering team to tackle challenges in drug discovery using cutting-edge machine learning, biophysical simulation, and computational chemistry. We seek passionate engineers eager to contribute to the development of innovative medicines and significantly enhance our software platform.Your ResponsibilitiesDevelop and sustain intricate computational chemistry workflows aimed at drug discovery.Collaborate closely with computational chemists and CADD scientists to implement new computational methodologies for predicting molecular properties.Assist in scaling our data infrastructure to accommodate billions of data points and manage hundreds of thousands of concurrent QM and molecular dynamics jobs.Your ProfileA critical thinker who approaches problems from first principles, balancing meticulous attention to detail with overarching architectural considerations, and possesses a strong curiosity to uncover root causes.Skilled in navigating all layers of the software stack, crafting user-friendly APIs and libraries for computational chemists.Proficient in computational chemistry and drug discovery, with a solid track record in writing production-grade code and successfully driving projects to fruition.What We OfferThe chance to develop impactful tools and products that are rapidly deployed to accelerate the discovery of new medicines.A team of highly skilled colleagues in AI, software, and chemistry, characterized by a blend of intellectual curiosity and humility. Our team engages in weekly discussions of 1-2 relevant machine learning or chemistry papers to stay abreast of advancements and inspire creativity.Competitive salary and equity package, along with comprehensive medical, dental, and vision insurance, and a 401(k) retirement plan.About Genesis Molecular AIGenesis Molecular AI is at the forefront of developing foundational models for molecular AI, heralding a new era in drug design and development. Our innovative generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), combines AI with physics to create leading models that generate and optimize drug molecules.

Join Our Team as a Senior / Staff Fullstack Software EngineerAt Genesis Molecular AI, we are assembling a premier software engineering team dedicated to revolutionizing drug discovery utilizing machine learning, biophysical simulations, and computational chemistry. We seek engineers passionate about developing innovative medicines and contributing significantly to our software platform.Your Responsibilities:Take ownership of our comprehensive full-stack platform utilized by computational chemists, enhancing functionalities ranging from data exploration to real-time visualizations, while delivering AI-driven workflows that expedite the hypothesis-to-insight cycle.Develop and enhance tools for visualizing molecular structures and proteins, analyzing machine learning models, and managing intricate chemical workflows.Collaborate closely with machine learning engineers and computational chemists to create and implement novel computational methods for predicting molecular properties.Expand our data infrastructure capabilities to accommodate billions of data points and thousands of parallel deep learning and molecular dynamics tasks.Your Profile:A critical thinker who approaches challenges from fundamental principles, adeptly balancing detail-oriented tasks with overarching architectural considerations, possessing a strong investigative drive to uncover root causes.Proficient in managing challenges across the full technology stack, including frontend interfaces, backend services, data pipelines, and overall infrastructure.Demonstrated experience in delivering production-level code and leading projects from inception to completion with minimal oversight.Eager to operate at the nexus of software engineering, drug discovery, and machine learning.What We Offer:An opportunity to work on impactful tools and products that are swiftly implemented to accelerate the discovery of new medications.A collaborative environment with skilled colleagues in AI, software, and chemistry, fostering a culture of intellectual curiosity and humility. The team engages in weekly discussions on 1-2 relevant machine learning or chemistry papers to stay abreast of advancements and inspire innovative ideas.Competitive compensation package, including salary and equity, along with comprehensive medical, dental, and vision insurance, and a 401(k) plan.

Role SummaryGenesis Molecular AI is looking for a dynamic Chief of Staff to support our CEO in enhancing operational effectiveness and strategic direction. This is a unique opportunity to work directly with a visionary leader at the forefront of artificial intelligence and drug discovery, within a company that has successfully raised over $300 million and forged significant partnerships in the pharmaceutical industry.In this pivotal role, you will be integral to the company's operations and future trajectory. You will oversee systems that ensure alignment among the leadership team, including quarterly and annual planning, board meeting preparations, and executive team facilitation, while also serving as the CEO's trusted voice in both internal and external communications.What You’ll DoStrategic Partnership: Collaborate closely with the CEO and leadership team to drive strategic initiatives and contribute to shaping the company’s strategic vision.Force Multiplier: Execute strategic projects on behalf of the CEO, harnessing resources and insights across the organization to achieve key objectives.Business Pulse: Regularly engage with teams across the organization to identify challenges, uncover inefficiencies, and connect insights that may go unnoticed by function-specific leaders.Operational Rhythm: Act as a thought partner on company strategy, and manage processes that maintain alignment and momentum within the leadership team, including OKR setting and meeting coordination.Cross-Functional Leadership: Drive cross-functional projects that do not fit neatly within a single department, ensuring urgent and comprehensive ownership of critical initiatives.Who You AreYou are an accomplished professional with a track record of getting things done. You are equally adept at analyzing data, preparing presentations, and engaging with senior executives. With a blend of analytical skills and intuitive judgment, you know when to leverage which skill to achieve results.Specifically:Intellectually Curious: You possess strong strategic judgment and analytical capabilities, able to navigate complex topics from technical whitepapers to market strategies with ease.

ML Research Engineer, Foundation ModelsAbout Our TeamBecome part of an elite team that is pioneering advancements in AI and biochemistry. At Genesis Molecular AI, we are a cohesive group of accomplished deep learning researchers, software engineers, and innovators in drug discovery.Our mission is transformative: to develop next-generation AI foundation models that will enable new therapies for patients facing severe diseases. We engage in groundbreaking research at the convergence of machine learning, physics, and computational chemistry, continually challenging the limits of these disciplines.The Genesis AI team is at the helm of this revolution, creating extensive generative models that are trained on a wide array of molecular data, backed by robust computational infrastructure and simulation processes.This position integrates machine learning research, structural biology, and computational chemistry, necessitating rigorous technical proficiency and strong collaborative skills across disciplines.About the Role We are seeking an exceptional ML Research Engineer who excels at merging fundamental research with production-level engineering.As a vital member of the Genesis AI team, you will be instrumental in inventing, scaling, and deploying our next generation of foundation models for molecular science.You will collaborate closely with ML researchers, computational chemists, and drug discovery scientists to transform cutting-edge model concepts into operational systems that drive real drug discovery initiatives.Your responsibilities will include:Enhancing model pretraining pipelinesAdvancing reinforcement learning and post-training systemsOptimizing the performance of large molecular modelsImplementing structure prediction models like Pearl in production environments utilized by chemists and drug initiativesWe require a professional who can bridge the gap between ML and computational chemistry, facilitating swift transitions from research insights to practical applications.

About the Role Roblox is hiring a Senior Software Engineer for the Compute Cell Platform team in San Mateo, CA. This team focuses on building and improving software that supports the core of the Roblox gaming platform. What You’ll Do Design and develop software to strengthen the Compute Cell Platform. Work closely with engineers and other teams to deliver solutions that support millions of users. Help shape the technical direction of the platform, aiming for reliability and performance. Collaboration This role involves regular collaboration with colleagues across engineering, product, and other functions to deliver features that improve the gaming experience for Roblox users.

Join Roblox as a Senior Software Engineer focusing on Compute Fleet Management. You will play a pivotal role in designing and developing scalable systems that manage compute resources, ensuring optimal performance and reliability for our user base.Your expertise will contribute to the advancement of our infrastructure, enhancing our capabilities in serving millions of players. Collaborate with cross-functional teams to deliver innovative solutions that shape the future of online gaming.

At Genesis Molecular AI, we are at the forefront of revolutionizing drug discovery by harnessing advanced machine learning, computational chemistry, and biology. Our mission is to expedite the development of transformative therapies by integrating cutting-edge technology with innovative scientific practices. We are assembling an exceptional team dedicated to propelling the future of drug discovery.About the Team:We are a passionate, mission-driven collective of scientists and engineers utilizing state-of-the-art computational techniques to discover drugs addressing unmet medical needs. Our work encompasses machine learning, computational chemistry, biology, and laboratory experimentation, all within a high-trust, technically sophisticated environment.You will join a team with exceptionally strong ML expertise that is actively advancing the application of AI in drug discovery. We are refining the integration of experimental data, biological context, and computational models to create a seamless feedback loop.You will play a crucial role in redefining the flow of data from experimentation to infrastructure, model, and decision-making, enhancing the speed and scale of our learning processes.The Role:This is a dynamic builder–integrator position within a highly technical, cross-disciplinary environment spanning AI/ML, engineering, computational chemistry, biology, and laboratory operations. You will act as a vital connector and acceleration engine across these domains.Collaborating closely with senior leadership, you will take ownership of roadmap definition and execution across critical internal platforms while driving structural improvements in our operational processes.Your primary objectives will include:Bridging domain silos and minimizing friction between ML experimentation and biological contextOperating at both the strategic and operational levelsGetting hands-on when necessaryClosing the AI ↔ Chemistry loop to ensure lab data is captured in a standardized format, accessible for model training, and contributes to measurable model performance enhancementsIncreasing iteration speed significantly from research idea to validated outcomeStandardizing execution across programs to scale effectively without reinventing workflows

Genesis Molecular AI is assembling an exceptional software engineering team dedicated to transforming drug discovery through innovative machine learning, advanced biophysical simulations, and computational chemistry. We are in search of passionate engineers eager to contribute to the development of groundbreaking medicines and play a pivotal role in enhancing our software platform.Your ResponsibilitiesLead the evolution of our full-stack platform utilized by computational chemists daily, encompassing data exploration, experiment management, and real-time visualization. You will create AI-driven workflows and modern interaction patterns to expedite insights from hypotheses.Develop and enhance tools for molecule and protein visualization, ML model analysis, and management of intricate chemical workflows.Collaborate with machine learning engineers and computational chemists to innovate and implement new computational techniques for predicting molecular properties.Expand our data infrastructure to accommodate billions of data points and numerous concurrent deep learning and molecular dynamics tasks.Your ProfileYou possess a deep analytical mindset, capable of reasoning from foundational principles while balancing meticulous detail with architectural vision, and you have a strong investigative drive to uncover the core of complex issues.You are comfortable managing challenges across the full stack, including frontend interfaces, backend services, data pipelines, and infrastructure.You have a proven track record of delivering production-ready code and driving projects from conception to completion with minimal supervision.You are excited to work at the convergence of software engineering, drug discovery, and machine learning.What We OfferA chance to work on impactful tools and products that are directly applied to expedite the discovery of new medicines.An environment of strong technical peers in AI, software development, and chemistry, all characterized by a blend of intellectual curiosity and humility. Our team engages in weekly discussions of 1-2 recent machine learning or chemistry papers to stay ahead and inspire innovative ideas.A competitive salary and equity package, along with comprehensive medical, dental, and vision insurance, and a 401(k) plan.About Genesis Molecular AIGenesis Molecular AI is pioneering the application of molecular AI technologies to revolutionize drug discovery, driving efficiency and effectiveness in the quest for new therapies.

About Our TeamAt Genesis Molecular AI, we are a dedicated group of innovative drug hunters, deep learning researchers, and skilled software engineers, all striving to revolutionize biochemistry. Our mission is to harness the power of AI to discover and develop groundbreaking therapies for patients dealing with severe disorders.Our team is engaged in pioneering the development of foundational models for small molecule drug discovery, conducting essential research at the intersection of machine learning, physics, and computational chemistry. We engineer robust software systems that support extensive simulations and facilitate the training of generative and predictive AI models capable of learning from diverse molecular data, leveraging a powerful cluster of thousands of GPUs and tens of thousands of CPUs.About the PositionWe are in search of talented ML Infrastructure Engineers who are ready to take the lead in advancing our machine learning research agenda for generative modeling of molecular systems, a key component of our mission.In this role, you will spearhead the rapid evolution of our AI platform and infrastructure, unlocking unprecedented levels of performance, efficiency, and scalability. You will be responsible for constructing massively distributed training and inference pipelines, core MLOps tools and frameworks, as well as optimizing GPU operations to enhance the speed of ML models.Genesis fosters a collaborative and cross-functional environment, offering the opportunity to work closely with our exceptional engineers, researchers, and scientists.Your ResponsibilitiesLead engineering initiatives aimed at the continuous enhancement of our AI platform, focusing on the rapid development of scalable and resilient distributed infrastructure for ML training, inference, and evaluation.Facilitate model training and deployment across multiple clusters and cloud environments, with an emphasis on optimizing throughput and cost-effectiveness.Maximize the efficiency of ML models and various workloads regarding latency, throughput, and memory usage (e.g., through GPU performance engineering), pushing the limits of current hardware capabilities.Contribute to the long-term strategic vision for Genesis’ infrastructure platform.QualificationsWe are looking for engineers with a strong foundation in software development and a passion for machine learning, particularly in the context of infrastructure and distributed systems.

About the Role Roblox is hiring a Principal Software Engineer focused on Compute Provisioning at our San Mateo, CA office. This role centers on building and improving the systems that power Roblox’s cloud infrastructure. Work closely with engineers and other teams to create and support scalable solutions for compute provisioning across the platform.

At Genesis Therapeutics, we are at the forefront of revolutionizing drug discovery by harnessing the power of machine learning, biophysical simulations, and computational chemistry. We are actively seeking a passionate Infrastructure Engineer to join our elite computational team. In this role, you will contribute to the development of groundbreaking medicines and play a pivotal part in the expansion of our advanced AI platform.Your Role:Collaborate with our infrastructure team to enhance and maintain our extensive multi-cloud compute infrastructure, which is vital for ML model training, computational chemistry research, and drug discovery initiatives.Develop and implement configurations and procedures for monitoring, resource allocation, and deployment automation to adapt to the growing demands of our autoscaling compute clusters.Contribute to the orchestration scheduling framework to boost execution throughput, increase reliability, and optimize compute utilization across diverse pipelines.Your Qualifications:Minimum of 5 years of experience in building and maintaining scalable cloud infrastructure, particularly with AWS or GCP.Proficient in Python, Bash, Terraform, Ray, and Kubernetes.Experience with distributed ML training jobs on compute clusters with over 1,000 GPUs is highly desirable.Hands-on experience with physical hardware and data center management is a plus.What We Offer:An opportunity to engage with impactful infrastructure that accelerates the discovery of new medicines.Be part of a world-class, close-knit team of dedicated professionals across software, machine learning, computational chemistry, medicinal chemistry, and biology.Competitive salary and equity options, alongside comprehensive medical, dental, and vision coverage, plus a 401(k) retirement plan.

Verkada seeks a Senior Staff Software Engineer to join the Platform Infrastructure team in San Mateo, CA. This senior technical position focuses on shaping and improving the core infrastructure that underpins Verkada's products, with particular attention to performance and scalability. Key Responsibilities Lead the design, building, and ongoing support of platform infrastructure. Partner with engineering teams to deliver software solutions that enable the platform to grow and adapt. Spot opportunities to improve reliability and efficiency, and guide initiatives to address them. Collaboration Frequent collaboration with cross-functional teams is central to this role. The goal is to ensure that infrastructure evolves to meet the demands of both current and future products.

Slickdeals is hiring a Staff Software Engineer based in either San Mateo, CA or Las Vegas, NV. This position centers on building and improving the systems that help millions of users find top deals every day. Role overview The Staff Software Engineer will work closely with teams across the company to design and deliver software solutions. The focus is on developing scalable features, improving user experiences, and supporting Slickdeals’ mission to connect people with great savings. Key responsibilities Lead and contribute to software projects that support the Slickdeals platform Collaborate with engineers, product managers, and designers to deliver new features Apply modern development practices and technologies to solve technical challenges Ensure solutions are scalable and responsive to changing user needs What you bring Expertise in software development and architecture Experience working with cross-functional teams Ability to develop solutions that scale for large user bases

Join Our Team at LuminaiLuminai is transforming healthcare operations by bridging the gap between human effort and technology. Our innovative solutions automate critical processes that have traditionally relied on manual work, enabling healthcare providers to focus on what truly matters: their patients. Despite the challenges faced by health systems, Luminai's platform organizes complexity, automates workflows, and integrates intelligence across systems to streamline operations and enhance patient care.Backed by leading investors from Silicon Valley—including General Catalyst, Peak XV, and YCombinator—Luminai is on a mission to redefine healthcare efficiency and productivity.About the OpportunityAs a Staff Software Engineer, you will be a key architect in developing our core platform, which is utilized globally for executing and scaling AI automations in essential production settings. Your expertise in software engineering fundamentals will be critical as you lead technical projects and contribute to our ambitious engineering goals. You will play a pivotal role in defining and enhancing the foundational systems that empower our engineering team to deliver an exceptional platform experience.Key ResponsibilitiesDevelop languages and associated tools (DSLs, parsers, compilers) for both internal and external system abstractions.Design and maintain distributed computing environments.Identify and resolve system bottlenecks, proactively re-architecting foundational abstractions to facilitate scalability.Lead technical initiatives that establish high-quality standards in the codebase.Define and enhance experimentation, monitoring, reliability, and observability strategies for production systems.Drive improvements to the core Luminai Integrated Development Environment (IDE) to ensure an outstanding user experience.

Why Choose PlayStation?At PlayStation, we believe that our platform is not only the ultimate destination for gaming but also the ideal workplace for talented individuals. As a globally recognized leader in the entertainment industry, we proudly develop the PlayStation family of products and services, including the acclaimed PlayStation®5, PlayStation®4, PlayStation®VR, PlayStation®Plus, and a wide array of award-winning software titles from PlayStation Studios.We are committed to fostering an inclusive environment that empowers our employees and celebrates diversity. We encourage all individuals who have a passion for innovation, technology, and play to apply for our open positions and become part of our dynamic global team.The PlayStation brand operates under Sony Interactive Entertainment, a wholly-owned subsidiary of Sony Group Corporation.

At Notable, we are at the forefront of revolutionizing healthcare through our advanced AI platform, designed to enhance workforce productivity. Our innovative solutions empower healthcare systems, hospitals, and payers to elevate care quality, bridge gaps in patient services, and drive member engagement—all while scaling operations without the need for additional personnel.Our mission is clear: to enrich the lives of patients, healthcare providers, and staff alike—creating a positive impact on healthcare for everyone. This isn't merely an aspiration; it's a reality we work towards daily. As part of Notable, you will join a dedicated team committed to transforming healthcare and aiming to positively influence the lives of 100 million patients.We cultivate a purposeful culture that empowers each team member to excel in their roles, collaborate with top talent, and enjoy the journey of achieving significant milestones together.Position Overview:We are seeking a talented Senior Fullstack Software Engineer to join our dynamic engineering team. In this role, you will utilize your extensive expertise to design, develop, and maintain high-performing web applications that significantly enhance healthcare delivery. Collaboration with cross-functional teams will be key as you implement innovative solutions, all aimed at improving patient care and optimizing healthcare workflows.Your Responsibilities:Architect and develop responsive, high-performance web applications that serve as the core of our healthcare AI platform.Engage with product managers and UX/UI designers to translate business needs into technical designs and intuitive user interfaces.Create and enhance RESTful APIs to facilitate seamless integrations with various healthcare systems and third-party services.Apply best practices for code quality, testing, and continuous integration/continuous deployment (CI/CD) to ensure software reliability and maintainability.Diagnose and resolve technical challenges across the entire stack, ensuring optimal front-end and back-end performance.Mentor junior engineers, offering guidance and expertise to nurture their development and enhance overall team capabilities.Collaborate closely with our data science team to deploy machine learning (ML) and natural language processing (NLP) algorithms into production applications, driving innovation in healthcare solutions.

Why Choose PlayStation?At PlayStation, we pride ourselves on being the ultimate destination for gaming enthusiasts and a premier workplace for talent. As a recognized global leader in the entertainment industry, we develop the PlayStation family of products and services, including the highly acclaimed PlayStation®5, PlayStation®4, PlayStation®VR, PlayStation®Plus, and a diverse range of award-winning software titles from PlayStation Studios.We are committed to fostering an inclusive environment that champions diversity and empowers our employees. We invite individuals with a passion for innovation, technology, and gaming to explore our open positions and become a vital part of our expanding global team.PlayStation operates under Sony Interactive Entertainment, a wholly-owned subsidiary of Sony Group Corporation.Staff Software Engineer, Client Engineer San Mateo, CA

As a Senior Staff Software Engineer focusing on Engineering Productivity at Verkada, you will play a pivotal role in enhancing our engineering processes and tools. Your expertise will help streamline workflows, improve development practices, and drive efficiency across our engineering teams. We are looking for a seasoned engineer who is passionate about building scalable systems and creating a productive environment for engineers.

About UsAt Verkada, we are revolutionizing the way organizations safeguard their people and assets through our cutting-edge, AI-driven platform. As a frontrunner in cloud-based physical security solutions, we empower organizations with enhanced safety and efficiency through a singular, integrated software platform that encompasses video security, access control, air quality monitoring, alarms, intercoms, and visitor management. With over 30,000 clients globally, including more than 100 Fortune 500 companies, Verkada is the trusted physical security partner for seamless management, intelligent oversight, and scalable implementations. Established in 2016, we have experienced rapid growth, with 15 offices and a workforce exceeding 2,200 dedicated professionals.Recent Projects for This Role IncludeDesigning and deploying a binary classifier using TensorFlow to detect binary states across hundreds of cameras.Identifying unusual object additions or removals within a scene.Counting and monitoring the frequency of objects and people.Your ResponsibilitiesHold a Bachelor’s Degree in Computer Science, ideally with research experience.Possess over 2 years of professional software engineering experience.Have at least 1 year of work or research experience with contemporary neural network frameworks.Exhibit proficiency in at least one practical programming language.Contribute effectively within an agile team software development setting.What You OfferProficient in C++, capable of writing clean, modular code.Familiarity with traditional computer vision algorithms.Experience in training deep learning networks utilizing TensorFlow, Keras, Caffe, or similar frameworks.Strong understanding of data structures and software architecture.Must be willing and able to work onsite five days a week.