Senior Machine Learning Engineer Home Modeling jobs in San Mateo – Browse 594 openings on RoboApply Jobs

Senior Machine Learning Engineer Home Modeling jobs in San Mateo

Open roles matching “Senior Machine Learning Engineer Home Modeling” with location signals for San Mateo. 594 active listings on RoboApply Jobs.

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companyRoblox logo
Full-time|$243.3K/yr - $295.3K/yr|On-site|San Mateo, CA, United States

At Roblox, we welcome millions of users daily to engage in immersive 3D experiences crafted by our vibrant community of developers and creators.Our mission is to empower this community by providing innovative tools and a platform that turn their imaginative ideas into reality. We aim to transform the way people connect globally, across all devices, fostering a spirit of optimism and civility as we work towards our goal of connecting one billion users.Joining Roblox means you will play a key role in shaping the future of human interaction, solving significant technical challenges, and enhancing shared experiences for all.As our user base grows at an unprecedented rate, we are on the lookout for proficient machine learning engineers who excel in tackling intricate challenges and developing scalable, cutting-edge solutions. In this influential role, you will create deep learning models focused on user insights, content analysis, and recommendation systems, thereby enhancing user engagement, retention, and growth in our creator ecosystem.Your contributions will be vital in refining the core systems that facilitate user discovery and interaction across Roblox. By enhancing exploration and engagement, you will help users find relevant and exciting content. Looking to the future, our team is dedicated to innovating personalized recommendation algorithms and advancing CV and NLP techniques to deepen our understanding of Roblox experiences.Join us and be a driving force in connecting a billion users with the optimal content and interactions at the perfect moment, addressing diverse challenges on an unprecedented scale.

Feb 10, 2026
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companyzaimler logo
Full-time|On-site|San Mateo, CA

About zaimlerAt zaimler, we recognize that AI agents struggle to make decisions based on fragmented data. Today’s enterprise data is scattered across numerous systems, lacking shared context and structure, which contributes to the challenges faced in enterprise AI. As we transition from copilots to fully autonomous agents, we're establishing a revolutionary infrastructure layer to support this evolution.zaimler serves as the foundational context infrastructure for the agentic era. Our platform autonomously uncovers domain knowledge, maps intricate relationships, and equips AI agents with the semantic understanding necessary for precise operations at scale. Envision knowledge graphs that facilitate real-time inference, designed specifically for systems that require reasoning capabilities, rather than mere data retrieval.Founded by industry veterans Biswajit Das and Sofus Macskassy, zaimler is a small yet highly skilled team at the seed stage, collaborating with major enterprises across sectors such as insurance, travel, and technology. If you aspire to develop the infrastructure that will underpin the next decade of AI advancements, we invite you to join our journey.About the RoleWe are in search of a Senior Machine Learning Engineer to enhance our dynamic team, ideally based in the Bay Area or open to relocation. The perfect candidate will possess strong expertise in one or more of the following areas: Knowledge Extraction, Natural Language Understanding, Unsupervised Learning, Information Retrieval, and Fine-tuning Large Language Models (LLMs). In this pivotal role, you will be instrumental in developing and training the models, pipelines, and methodologies that drive our semantic graph systems. We seek an individual with a robust background in machine learning, natural language processing, LLMs, and semantic technologies, along with a proven history of managing complex, large-scale machine learning projects.

Nov 27, 2024
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companyGenesis Therapeutics logo
Full-time|On-site|San Mateo, CA

Join Our Innovative TeamAt Genesis Molecular AI, we are a dedicated group of skilled deep learning researchers, software engineers, and pioneers in drug discovery. Our collective mission is to develop pioneering AI foundation models that will enable revolutionary therapies for patients suffering from severe conditions.We don't merely implement machine learning in biology; we engage in groundbreaking research at the convergence of machine learning, physics, and computational chemistry, challenging the limits of each discipline. As part of the Genesis AI team, you will collaborate with top-tier multidisciplinary researchers to design and construct generative and discriminative foundation models from an extensive range of molecular data, utilizing state-of-the-art computing resources and large-scale simulations.Your RoleThis position provides a unique platform for a scientific innovator to contribute to the future of generative AI in drug discovery. As an integral member of the Genesis AI team, you will guide and propel our research initiatives focusing on foundation models. You will spearhead significant research projects in areas such as reinforcement learning, innovative model architectures, and advanced pretraining and post-training techniques. Your primary goal will be to develop groundbreaking models and insights crucial for discovering new medications.This role demands a profound curiosity and a collaborative mindset. You will be an essential team player, working closely with our exceptional engineers and drug discovery specialists to transform complex concepts into reality. Additionally, we encourage you to be an influential voice in the scientific community, and we will actively support your efforts to publish research breakthroughs at premier ML conferences such as NeurIPS, ICML, and ICLR.Positions are available at several levels of seniority: Senior, Staff, and Principal.Key ResponsibilitiesLead transformative research projects from initiation to execution, addressing core challenges in generative modeling for molecular systems.Design and develop innovative models and algorithms, leveraging the latest advancements in diffusion models, flow matching, reinforcement learning, large language models, and other cutting-edge fields.

Jul 30, 2025
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companyRoblox logo
Full-time|$195.8K/yr - $242.1K/yr|On-site|San Mateo, CA, United States

At Roblox, millions of individuals engage daily to explore, create, play, learn, and connect with friends in immersive 3D digital experiences crafted by our global community of developers and creators.We are dedicated to building tools and platforms that empower our community to realize their imaginative experiences. Our vision is to transform how people connect from anywhere in the world and on any device. Our mission is to unite one billion people with optimism and civility, and we are seeking exceptional talent to help us achieve this goal.Joining Roblox means you will play a pivotal role in shaping the future of human interaction, tackling unique technical challenges at scale, and contributing to the creation of safer, more civil shared experiences for all.The Rights Manager and Content Suitability teams, part of our Safety Experience, are in search of a Senior Machine Learning Engineer.The Safety Experience organization develops tools and systems that empower Roblox users and creators to control their experiences while enabling moderators to uphold our community standards. Our focus includes education, intervention, visibility, and action.Our initiatives include:Monitoring and influencing user behavior for enhanced safety.Building scalable and efficient moderation platforms.Providing transparency and educational resources for parents and developers.Empowering users to manage their own safety.Allowing IP owners to manage their creations on Roblox.Delivering quick and accurate support through our Customer Care Chatbot.Your responsibilities will include:Implementing machine learning solutions for safety-focused systems.Promoting a culture of technical excellence and inclusivity.Breaking down long-term product requirements into actionable phases for continuous improvement.Designing and building large-scale machine learning models with billions of parameters, ensuring they are production-ready.Facilitating complex technical decisions with empathy and foresight.

Feb 10, 2026
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company
Full-time|On-site|San Mateo, CA

About the TeamBecome a part of a pioneering team at the intersection of artificial intelligence and biochemistry.At Genesis Molecular AI, we are a dynamic collective of distinguished deep learning researchers, software engineers, and innovators in drug discovery. Our ambitious mission is to develop the next frontier of AI foundation models to unlock revolutionary treatments for patients battling serious diseases.We are not merely applying machine learning to biological problems; we are engaged in groundbreaking research that bridges machine learning, physics, and computational chemistry, challenging the limits of each discipline. The Genesis AI team is constructing the engine for this transformation. You will collaborate closely with leading multidisciplinary researchers to design and implement generative and discriminative foundation models at scale, utilizing extensive computational resources and large-scale simulations.About the RoleThis is a unique opportunity for a scientific innovator to influence the future landscape of generative AI in drug discovery. As a pivotal member of the Genesis AI team, you will direct our research strategy for foundation models. You will spearhead critical research initiatives in areas such as reinforcement learning, innovative model architectures, and advanced pretraining and post-training techniques. Your primary goal will be to develop transformative models and insights that play a crucial role in the discovery of new medications.This position demands a profound curiosity and a commitment to collaboration. You will be an integral team player, partnering closely with our exceptional engineers and drug discovery specialists to realize complex concepts. Additionally, we encourage you to engage with the scientific community, and we will actively support your endeavors to publish significant research findings in prestigious ML conferences such as NeurIPS, ICML, and ICLR.We are hiring for various levels of seniority: Senior, Staff, and Principal.Your ResponsibilitiesLead innovative research projects from inception to execution, addressing fundamental challenges in generative modeling for molecular systems.Design and develop advanced models and algorithms, leveraging the latest advancements in diffusion models, flow matching, reinforcement learning, and large language models.Conduct large-scale experiments utilizing our premier computational resources to validate your research.

Jul 30, 2025
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companyRoblox logo
Full-time|$259K/yr - $311.4K/yr|On-site|San Mateo, CA, United States

Roblox is a dynamic platform where millions engage daily to explore, create, and connect within immersive 3D digital experiences crafted by our global community of developers and creators.We are dedicated to building tools and a platform that empower our community to transform their imaginative ideas into reality. Our vision aims to revolutionize the way people connect, enabling interactions from anywhere in the world and on any device. Our mission is to connect a billion people with positivity and respect, and we are in search of exceptional talent to help us achieve this goal.Joining Roblox means you will be at the forefront of shaping the future of human interaction, tackling unique technical challenges at scale, while enhancing safety and civility in shared experiences for everyone.As the number of daily active users on Roblox continues to surge, we are looking for skilled machine learning engineers who excel in solving complex problems and designing scalable, innovative solutions. In this pivotal role, you will create deep learning models for our performance advertising business, establishing the groundwork for effective ads that benefit our users and deliver significant value to our advertisers.You'll be tasked with developing cutting-edge machine learning solutions that enhance ad ranking algorithms and create personalized advertising experiences. As our advertising system is still evolving, this role presents a unique chance to shape and build a world-class ML-driven advertising platform from the ground up.

Feb 10, 2026
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companyRoblox Corporation logo
Full-time|On-site|San Mateo, CA, United States

Join Roblox as a Senior Software Engineer, specializing in Machine Learning Infrastructure. In this role, you will be a key player in designing and developing robust ML systems to enhance our gaming platform. You will collaborate with cross-functional teams to implement scalable solutions that elevate user experiences. Your expertise will directly influence the future of gaming at Roblox.

Apr 1, 2026
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companyRoblox logo
Full-time|$195.8K/yr - $242.1K/yr|On-site|San Mateo, CA, United States

At Roblox, our platform allows millions of users to explore, create, and connect in immersive 3D experiences crafted by our diverse community of developers. Every day, players from around the globe engage in imaginative play and learning, and we are dedicated to empowering them with the tools they need to bring their visions to life.Our mission is to foster a connected world, inspiring a billion people to engage with optimism and respect. We are seeking exceptional talent to join us on this journey, shaping the future of human interaction and tackling unique challenges at scale to create safe, enjoyable shared experiences.As a Senior Machine Learning Engineer at Roblox, you will tackle complex problems using cutting-edge AI and machine learning technologies to innovate the experiences of our growing user community. We are looking for leaders in AI and ML to spearhead the development of cost-effective machine learning solutions, guiding the design of essential components for on-device ML operations. Your work will focus on enhancing model architectures, facilitating efficient deployment to cloud and client systems, and managing sophisticated tasks such as Generative AI model deployment. You will play a key role in optimizing architectures across a variety of compute devices, making the best use of available resources. Join us in our exciting journey!

Feb 10, 2026
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companyRoblox logo
Full-time|$242.1K/yr - $293.8K/yr|On-site|San Mateo, CA, United States

Every day, millions of users engage with Roblox, diving into immersive 3D experiences crafted by our vibrant global community of developers and creators.At Roblox, we empower our community with innovative tools and platforms that bring their imaginations to life. Our mission is to transform how people connect from anywhere, on any device, fostering a world of optimism and civility. We are seeking exceptional talent to help us reach our goal of connecting a billion people.Embarking on a career at Roblox means shaping the future of human interaction, tackling unique technical challenges at scale, and creating safer, more respectful shared experiences for all.As our Ads business rapidly expands, we are developing a large-scale machine learning infrastructure aimed at delivering impactful performance ads to our user base and substantial value to our advertisers.In the role of Senior Machine Learning Infrastructure Engineer within our Ads ML Infra team, you will design and implement scalable, reliable, and high-performance infrastructure that underpins machine learning systems throughout our organization. You will work with vast datasets, handling hundreds of billions of engagements while redefining how we deliver performance ads to millions.

Feb 10, 2026
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companyRoblox Corporation logo
Full-time|On-site|San Mateo, CA, United States

Join Roblox as a Senior Machine Learning Engineering Manager and lead a dynamic team focused on developing cutting-edge machine learning solutions. In this role, you will be responsible for overseeing the design, implementation, and optimization of algorithms that enhance user experience and gameplay. Your leadership will guide the team in leveraging data to drive strategic decisions, ensuring our platform remains at the forefront of technology.

Mar 24, 2026
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companyRoblox logo
Full-time|$195.8K/yr - $242.1K/yr|On-site|San Mateo, CA, United States

Roblox is a vibrant platform where millions of users come together to explore, create, play, learn, and connect in immersive 3D experiences crafted by a diverse global community of developers.At Roblox, we are dedicated to building innovative tools and a robust platform that empower our community to bring their imaginative experiences to life. Our vision is to transform how people unite, no matter where they are in the world or what device they use. We are on a mission to connect a billion individuals with optimism and civility, and we seek exceptional talent to help us achieve this goal.Joining Roblox means you will be at the forefront of shaping the future of human interaction, tackling unique technical challenges at scale, and creating safer, more respectful shared experiences for all.Our engine's resource management and streaming systems are crucial for providing a seamless, stable, and responsive experience for Roblox users across a vast array of devices and network conditions. These systems collaboratively manage compute, memory, bandwidth, and rendering quality while delivering dynamic world content in real time as players interact with their environments. The challenges we face include highly dynamic environments, unpredictable user behaviors, and opaque signals stemming from device and OS limitations.This position offers a unique chance to lead the integration of machine learning into real-time engine optimization. You will develop the ML framework for predictive resource allocation and content fetching, transitioning from heuristic-based logic to adaptive, data-driven decision-making. Your contributions will directly influence stability, visual quality, responsiveness, and content delivery across billions of global play sessions.

Feb 10, 2026
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companyRoblox logo
Full-time|$195.8K/yr - $242.1K/yr|On-site|San Mateo, CA, United States

Roblox is a dynamic platform where millions of users venture daily to explore, create, engage, and connect with friends in immersive 3D digital environments crafted by our vibrant community of developers and creators.At Roblox, we are dedicated to developing tools and platforms that empower our community to transform their imaginative ideas into reality. Our vision is to redefine global connectivity, enabling people to come together from anywhere in the world, accessible on any device. We are on a mission to unite a billion people with positivity and respect, and we are seeking exceptional talent to help us achieve this goal.A career at Roblox means you will play a pivotal role in shaping the future of human interaction, tackling unique technical challenges on a grand scale, and contributing to the creation of safer, more respectful shared experiences for all.The Foundation AI Group aims to position Roblox as the benchmark for 3D foundational models (3DFMs), making it easier for anyone to craft high-quality, immersive 3D experiences using AI. The AI Platform team is integral to this vision, managing hundreds of machine learning use cases and handling billions of inferences daily across areas like Discovery, Safety, and Engine. We are searching for exceptional PhD graduates to spearhead innovation in three vital areas: AI Platform, Distributed Inference Systems, and Generative AI Information Retrieval.Your RoleAs a Senior Machine Learning Engineer on the AI Platform team, you will be a vital contributor to the development of innovative systems that drive AI at Roblox. You will concentrate on one of three significant tracks:Track 1: AI Platform ProjectsLead the development of next-generation AI tools that improve the efficiency, cost, and usability of ML@Roblox.Build and sustain essential platform components: Serving Layer, Model Registry, Pipeline Orchestrator, and Training/Inference control planes.Craft outstanding developer experiences (templates, tools, visualizations) to reduce time-to-production and ensure foundational AI systems are scalable and reliable.Track 2: Distributed Inference & Systems OptimizationDesign and implement scalable distributed inference systems for efficiently serving large language models (LLMs) and Large Recommender Models at unprecedented scale.Perform in-depth, low-level performance analysis to optimize systems.

Feb 10, 2026
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companyGenesis Therapeutics logo
Full-time|On-site|San Mateo, CA

Join Our Team as a Senior ML Research Engineer, Foundation ModelsAbout UsBecome part of a cutting-edge team at Genesis Molecular AI, where we are dedicated to pioneering advancements at the intersection of artificial intelligence and biochemistry. Our accomplished group comprises distinguished deep learning researchers, software engineers, and innovators in drug discovery.Our mission is transformative: to develop innovative AI foundation models that provide breakthrough therapies for patients with critical health challenges. We conduct essential research that amalgamates machine learning, physics, and computational chemistry, continuously pushing the boundaries of these disciplines.At Genesis AI, we are constructing the core infrastructure for this revolutionary work. We design and implement large-scale generative models, leveraging comprehensive molecular data supported by robust computational resources and simulation pipelines.About the RoleWe are seeking a highly proficient ML Research Engineer who excels in bridging fundamental research with production-level engineering.As an integral member of the Genesis AI team, you will be instrumental in conceptualizing, scaling, and deploying our next generation of foundation models for molecular science.Collaboration is key, as you will work closely with ML researchers, computational chemists, and drug discovery scientists to translate pioneering model concepts into actionable systems that drive real drug discovery initiatives.Key ResponsibilitiesEnhancing and scaling model pretraining pipelinesAdvancing reinforcement learning and post-training systemsOptimizing the performance of extensive molecular modelsImplementing structure prediction models like Pearl into production settings utilized by chemists and drug programsThis position requires an individual capable of integrating ML and computational chemistry, facilitating swift transitions from research insights to practical applications.

Jul 30, 2025
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companyFireworks AI logo
Full-time|$170K/yr - $240K/yr|On-site|New York, NY; San Mateo, CA

About Us:At Fireworks AI, we are pioneering the future of generative AI infrastructure. Our platform is recognized for delivering the highest-quality models with the fastest and most scalable inference capabilities in the industry. Proudly benchmarked as a leader in LLM inference speed, we are at the forefront of innovation with projects like function calling and multimodal models. As a Series C company valued at $4 billion, we are supported by prestigious investors including Benchmark, Sequoia, Lightspeed, Index, and Evantic. Our team comprises ambitious builders, many of whom hail from Meta PyTorch and Google Vertex AI.The Role:As an Applied Machine Learning Engineer, you will play a crucial role in bridging the gap between advanced AI research and practical applications. Your responsibilities will include developing, fine-tuning, and operationalizing machine learning models that deliver significant business value and enhance user experiences. This hands-on engineering position demands a blend of deep technical expertise and a strong customer-centric approach to create scalable AI solutions.Key Responsibilities:Customer Success: Collaborate with the Go-To-Market (GTM) team, including Account Executives and Solutions Architects, to ensure seamless integration and successful deployment of machine learning solutions.Demo / Proof of Concept (PoC): Develop and present engaging PoCs that showcase the capabilities of our AI technology.Application Build: Design, develop, and deploy end-to-end AI-powered applications customized to meet customer needs.Platform Features / Bug Fixes: Contribute to the internal machine learning platform by adding features and resolving issues.New Model Enablements: Integrate and enable new machine learning models within the existing platform or client environments.Performance Optimizations: Enhance the performance, efficiency, and scalability of deployed models and applications.Partnership Enablement: Collaborate closely with partners to facilitate joint AI solutions and ensure effective collaboration.

Mar 5, 2026
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companyRoblox logo
Full-time|$397.5K/yr - $455.7K/yr|On-site|San Mateo, CA, United States

Roblox is a vibrant platform where millions of users engage daily to explore, create, play, learn, and connect through immersive 3D experiences, all crafted by our diverse community of developers and creators.At Roblox, we are dedicated to building innovative tools and platforms that empower our community to turn their imaginative experiences into reality. Our vision is to revolutionize how people connect from anywhere in the world, across any device. We are on a purposeful mission to unite a billion individuals with positivity and respect, and we are seeking exceptional talent to help us achieve this goal.Joining Roblox means contributing to the evolution of human interaction, tackling unique technical challenges at scale, and fostering safer, more respectful shared experiences for all.In the role of Distinguished Machine Learning Engineer/Technical Director within the Safety organization at Roblox, you will spearhead the technical vision and execution of machine learning projects aimed at ensuring user safety and promoting civility. Our top-tier safety features are what make Roblox a secure and inclusive space for creative expression and shared experiences. The Safety team plays a critical role in maintaining Roblox as one of the safest platforms on the internet, protecting users as our platform grows to accommodate diverse age groups and locations.You Will:Take ownership of the technical direction and implementation of machine learning solutions for safety systems.Lead and mentor fellow engineers, fostering an environment of technical excellence and inclusivity.Translate long-term product requirements into manageable milestones, ensuring ongoing enhancements.Design and develop large-scale machine learning models with billions of parameters, ensuring they are production-ready.Navigate complex technical decisions across teams, showcasing empathy and fostering mutual understanding.Work collaboratively with cross-functional teams to outline and prioritize the machine learning roadmap.

Feb 10, 2026
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company
Full-time|On-site|San Mateo

About WisdomAIAt WisdomAI, we are committed to democratizing access to data and insights for everyone. We leverage the transformative potential of Generative AI to revolutionize how organizations utilize data for informed decision-making. Join us now, as we partner with multiple Fortune 100 companies and embark on an exciting journey to shape the future of data accessibility and understanding.Position OverviewWe are on the lookout for talented Machine Learning and Natural Language Processing engineers to join our dynamic team. You will tackle core challenges in large language model (LLM) code generation, document comprehension, context synthesis, and the development of LLM-based agents. Our team is comprised of seasoned professionals who hail from industry leaders such as Glean, Apple, Rubrik, Google, and Meta.Key ResponsibilitiesDevelop workflows and agentic pipelines to handle complex analytical tasks.Design and implement an evaluation framework for our query processing engine.Collaborate closely with customers and founders to establish the product and engineering roadmap.Influence the engineering culture and technology stack at WisdomAI.

Feb 3, 2026
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companyGeneralist logo
Full-time|On-site|San Francisco Bay Area (San Mateo) or Boston (Somerville)

About the RoleAt Generalist, we are at the forefront of training expansive robot foundation models, leveraging cutting-edge GPU hardware, primarily from Nvidia, to execute distributed training tasks and experimental research. Our operations demand exceptional storage solutions and optimized data loading processes, necessitating the full utilization of cloud infrastructure alongside custom-built solutions.In this role, you will take charge of our inference infrastructure. Our robotic systems rely on a dedicated fleet of on-premises GPUs designed for demanding real-time computations and latency-sensitive applications within resource-constrained environments.Your Responsibilities:Manage and optimize our GPU compute fleets.Facilitate user-friendly access to GPUs for researchers, ensuring optimal utilization.Enhance ML data loading, transport, and storage systems in extensively utilized distributed environments.Oversee the orchestration of our robot inference fleets.You May Excel in This Position If You:Have experience managing large GPU fleets for large-scale, distributed training or inference.Possess significant expertise in using Slurm or Kubernetes for ML workload orchestration.Have developed high-scale ML data loaders and preparation systems.Understand the intricacies of ML hardware, storage, and networking systems.Are familiar with the Nvidia GPU ecosystem.

Feb 12, 2026
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company
Full-time|On-site|San Mateo, CA

ML Research Engineer, Foundation ModelsAbout Our TeamBecome part of an elite team that is pioneering advancements in AI and biochemistry. At Genesis Molecular AI, we are a cohesive group of accomplished deep learning researchers, software engineers, and innovators in drug discovery.Our mission is transformative: to develop next-generation AI foundation models that will enable new therapies for patients facing severe diseases. We engage in groundbreaking research at the convergence of machine learning, physics, and computational chemistry, continually challenging the limits of these disciplines.The Genesis AI team is at the helm of this revolution, creating extensive generative models that are trained on a wide array of molecular data, backed by robust computational infrastructure and simulation processes.This position integrates machine learning research, structural biology, and computational chemistry, necessitating rigorous technical proficiency and strong collaborative skills across disciplines.About the Role We are seeking an exceptional ML Research Engineer who excels at merging fundamental research with production-level engineering.As a vital member of the Genesis AI team, you will be instrumental in inventing, scaling, and deploying our next generation of foundation models for molecular science.You will collaborate closely with ML researchers, computational chemists, and drug discovery scientists to transform cutting-edge model concepts into operational systems that drive real drug discovery initiatives.Your responsibilities will include:Enhancing model pretraining pipelinesAdvancing reinforcement learning and post-training systemsOptimizing the performance of large molecular modelsImplementing structure prediction models like Pearl in production environments utilized by chemists and drug initiativesWe require a professional who can bridge the gap between ML and computational chemistry, facilitating swift transitions from research insights to practical applications.

Jul 30, 2025
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companyGenesis Therapeutics logo
Full-time|On-site|San Mateo, CA

Join Our Innovative TeamAt Genesis Therapeutics, we are a dynamic and passionate group of drug discovery experts, deep learning researchers, and software engineers dedicated to revolutionizing biochemistry through AI. Our mission is clear: to uncover and develop transformative therapies for patients with severe medical conditions.Our AI team is at the forefront of creating foundational models for small molecule drug discovery. We conduct cutting-edge research that bridges machine learning, physics, and computational chemistry, while building resilient software systems capable of executing large-scale simulations and training advanced generative and predictive AI models utilizing our powerful cluster of thousands of GPUs and tens of thousands of CPUs.Your RoleWe are on the lookout for skilled ML infrastructure engineers to propel our machine learning research initiatives, particularly in generative modeling of molecular systems, which is vital to our overarching goals.In this position, you will spearhead the rapid advancement of our AI platform and infrastructure, enhancing performance, efficiency, and scalability to unprecedented levels. You will construct expansive distributed training and inference pipelines, essential MLOps tools and frameworks, and fine-tune GPU operations to accelerate ML model performance.Genesis fosters a collaborative and interdisciplinary environment, allowing you to work closely with our talented engineers, researchers, and scientists.Your ResponsibilitiesDrive engineering initiatives aimed at the continuous enhancement of our AI platform, focusing on the rapid development of scalable and robust distributed infrastructures for ML training, inference, and evaluation.Facilitate model training and deployment across various clusters and cloud environments, optimizing for throughput and cost-effectiveness.Maximize the efficiency of ML models and other workloads in terms of latency, throughput, and memory usage, particularly through GPU performance engineering, pushing the boundaries of current hardware capabilities.Contribute to the long-term strategic vision for Genesis’ infrastructure platform.Your ProfileA strong engineering background with a focus on machine learning infrastructure.

Nov 24, 2025
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companyRoblox Corporation logo
Full-time|On-site|San Mateo, CA, United States

Join Roblox as a Principal Machine Learning Engineer focused on enhancing reliability across our systems. In this pivotal role, you will leverage cutting-edge machine learning techniques to ensure the seamless performance and reliability of our platform. Collaborate with cross-functional teams to design and implement robust ML algorithms that enhance user experience and system functionality.

Mar 12, 2026

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