Threat Detection Engineer at Ambience Healthcare | San Francisco

About Us:At Ambience Healthcare, we are not just another documentation service; we are pioneering an AI-driven platform that reintroduces humanity into healthcare, creating substantial returns on investment for health systems nationwide.Our innovative technology empowers healthcare providers to concentrate on exceptional patient care by alleviating the administrative burdens that detract from their crucial responsibilities. We provide real-time, coding-aware documentation and clinical workflow assistance across various healthcare settings, including ambulatory, emergency, and inpatient environments, collaborating with the leading health systems in North America.We are committed to delivering the best solutions for our partners, operating with a strong sense of ownership and a culture that values transparency, positivity, and thoughtful discussion. Our team holds each other to high standards because we understand the significance of the challenges we tackle.Recognized as a leader in enhancing clinician experiences by KLAS Research, featured by Fast Company as one of the Next Big Things in Tech, acknowledged by Inc. as one of the best AI companies in healthcare, and listed as a LinkedIn Top Startup for 2024 and 2025, Ambience is backed by prestigious investors including Oak HC/FT, Andreessen Horowitz (a16z), OpenAI Startup Fund, and Kleiner Perkins. Our journey is just beginning.The Role:As a key member of our team, you will spearhead the detection engineering and incident response program within a HIPAA-compliant, AI-driven environment, where the threat landscape includes LLM-powered agents operating across diverse infrastructures. Your responsibilities will include writing production code, architecting security data pipelines, and establishing high standards for detection and response within a rapidly evolving attack surface.This position requires a hybrid work model based in our San Francisco office (3 days per week).What You’ll Own:Detection Engineering: Establish a detection pipeline covering our highest-risk surfaces, including AWS, Kubernetes, Okta, endpoints, and SaaS tools. Create environment-specific detections that ensure reliable alerting for the on-call team.Incident Response: Develop a comprehensive incident response program, including playbooks, escalation processes, evidence collection, and post-mortems. Ensure all procedures are well-documented, practiced, and meet regulatory requirements.

Join Our Team:At Ambience Healthcare, we are pioneering an AI intelligence platform that enhances the human touch in healthcare while delivering substantial ROI for health systems nationwide. Our innovative technology enables healthcare providers to concentrate on delivering exceptional patient care by alleviating the administrative tasks that distract them from their critical responsibilities.We provide real-time, coding-aware documentation and clinical workflow support across various settings, including ambulatory, emergency, and inpatient care, partnering with the leading health systems in North America.Our team is dedicated to exhibiting extreme ownership to create the best solutions for our partners. We foster a culture of transparency, positivity, and deep thinking, striving for excellence because we understand the significance of the challenges we tackle.Ambience has been recognized as the top company for improving clinician experience in the KLAS Research Emerging Solutions Top 20 Report, hailed by Fast Company as one of the Next Big Things in Tech, named one of the best AI companies in healthcare by Inc., and listed as a LinkedIn Top Startup in both 2024 and 2025. We are supported by esteemed investors including Oak HC/FT, Andreessen Horowitz (a16z), OpenAI Startup Fund, and Kleiner Perkins — and our journey is just beginning.

About Us:At Ambience Healthcare, we are more than just a technology company; we are pioneers in creating AI-driven solutions that bring the human touch back to healthcare. Our innovative platform is designed to reduce administrative burdens, allowing healthcare providers to concentrate on what truly matters: delivering exceptional patient care.We specialize in real-time, coding-aware documentation and clinical workflow support across a variety of healthcare settings, including ambulatory, emergency, and inpatient environments, working with top health systems across North America.Our team embodies a culture of extreme ownership and collaboration, striving to develop the best solutions for our partners and tackling vital challenges in the healthcare industry. We prioritize transparency, positivity, and deep thinking, holding ourselves to high standards because we recognize the significance of the problems we address.Ambience has been awarded #1 for Improving the Clinician Experience in the KLAS Research Emerging Solutions Top 20 Report, recognized by Fast Company as a leading tech innovator, named one of the best AI companies in healthcare by Inc., and selected as a LinkedIn Top Startup for both 2024 and 2025. Our growth is backed by eminent investors such as Oak HC/FT, Andreessen Horowitz (a16z), OpenAI Startup Fund, and Kleiner Perkins — and we are just beginning our journey.The Role:As a Staff Security Engineer, you will play a crucial role in safeguarding our platform within some of the most security-sensitive health systems in the nation. Security must be ingrained in our product from the ground up, not merely an afterthought.In this position, you will oversee the systems that shield our platform at scale, focusing on application security, cloud security, detection and response, and foundational security primitives that other teams rely on. Your responsibilities will include designing security frameworks that make secure choices the default, fortifying our infrastructure against potential threats, and collaborating with engineering teams to minimize risks effectively.This is a hands-on role; you will engage in coding, system design, and lead comprehensive security initiatives that foster enterprise trust and facilitate customer growth.What You’ll Own:Application & Platform Security — Develop and implement secure-by-default patterns across our backend and infrastructure, identifying and rectifying vulnerabilities in application logic, APIs, and data flows.Cloud & Infrastructure Security — Manage the security posture of our cloud environment, focusing on IAM, network boundaries, secrets management, and secure service-to-service communication.Detection & Incident Response — Construct and maintain detection pipelines, alerts, and runbooks, spearheading investigations to ensure swift and effective incident response.

About Us:At Ambience Healthcare, we're not just another software company; we're revolutionizing healthcare through our cutting-edge AI intelligence platform. Our mission is to enhance the clinician experience by alleviating administrative burdens, enabling healthcare providers to focus on what truly matters—their patients.Our innovative technology delivers real-time, coding-aware documentation and clinical workflow support across various healthcare settings, including ambulatory, emergency, and inpatient care. We partner with leading health systems in North America, and our team operates with a deep commitment to ownership and excellence, striving to deliver the best solutions for our partners. We foster a culture of transparency, positivity, and thoughtful collaboration.Recognized as a leader in the field, Ambience has been ranked #1 for Improving the Clinician Experience in the KLAS Research Emerging Solutions Top 20 Report, honored by Fast Company as one of the Next Big Things in Tech, and named one of the best AI companies in healthcare by Inc. We’re proud to be a LinkedIn Top Startup for 2024 and 2025, backed by prominent investors such as Oak HC/FT, Andreessen Horowitz (a16z), OpenAI Startup Fund, and Kleiner Perkins.The Role:As a Senior Software Engineer on our AI Platform team, you will play a pivotal role in designing, building, and maintaining the core infrastructure that supports healthcare providers utilizing our platform daily. Joining an OpenAI portfolio company means you'll work alongside some of the brightest minds in AI and be at the forefront of technological advancements.In your first six months, your focus will be on establishing a robust foundation for long-term success, enhancing platform observability, reliability, and scalability. You will lead major technical initiatives within our AI stack, overseeing everything from system design to the deployment of your code.Note: Our Engineering roles are hybrid, requiring in-office presence in San Francisco three times a week.

About AbridgeAbridge, established in 2018, is dedicated to enhancing understanding in healthcare. Our innovative AI platform is specifically designed for medical conversations, streamlining clinical documentation processes and allowing clinicians to prioritize patient care.Our advanced technology converts patient-clinician discussions into structured clinical notes in real-time, featuring robust EMR integrations. With our unique Linked Evidence and auditable AI, we stand out as the only company that aligns AI-generated summaries with verified ground truth, enabling healthcare providers to trust and validate our outputs swiftly. As leaders in generative AI for healthcare, we are setting benchmarks for the ethical application of AI within health systems.Our diverse team comprises practicing MDs, AI scientists, PhDs, creatives, technologists, and engineers, all collaborating to empower individuals and enhance healthcare delivery. Our offices are located in San Francisco's Mission District, New York's SoHo neighborhood, and Pittsburgh's East Liberty.The RoleAre you ready to build robust security measures at the forefront of AI in healthcare? We are seeking a highly skilled and motivated Senior or Staff Threat Detection and Response Engineer to join our pioneering Abridge Security Operations team. As one of our initial engineers, you will play a crucial role in elevating the costs for any adversary targeting our organization or our clients.This role demands profound technical knowledge, a builder’s mindset, and exceptional communication abilities to foster a security-centric culture across the organization. This is a greenfield opportunity to shape the future of Threat Detection and Response at Abridge. You will excel here if you are passionate about creating solutions from scratch and recognize that modern security fundamentally revolves around large-scale data and automation challenges.What You’ll DoLead investigations into complex, organization-wide security incidents, establishing best practices across various security domains including log analysis, digital forensics, and malware analysis.Design and implement a strategic roadmap for threat detection capabilities, developing high-fidelity detection systems informed by a deep understanding of advanced threat actor tactics, techniques, and procedures (TTPs).Architect scalable incident response processes while driving automation throughout the entire incident response lifecycle, establishing effective patterns for the organization.Act as a key technical leader and influence security practices organization-wide.

Role Overview Writer Inc. is hiring a Security Engineer focused on Detection and Response in San Francisco, CA. This position centers on building and maintaining security controls that safeguard the company’s digital assets. What You Will Do Develop and implement security measures to protect systems and data. Collaborate with teams across the company to strengthen security practices. Respond to security incidents and help improve incident response processes. Location This role is based in San Francisco, CA.

About Our TeamAt OpenAI, we believe that the development of artificial general intelligence must be conducted in a way that is safe and beneficial for all of humanity. Security is paramount to our mission and underpins every aspect of our work.Our Security team is dedicated to safeguarding OpenAI’s technology, personnel, and products. We adopt a highly technical approach to our creations while maintaining operational excellence in execution. Our core tenets include prioritizing impactful initiatives, empowering our researchers, anticipating future technological advancements, and fostering a robust security culture.About the PositionAs a Security Engineer specializing in insider threat detection and response, you will collaborate with our talented engineers and researchers to build and secure groundbreaking AI technologies. This role emphasizes the identification and mitigation of insider threats, ensuring the protection of OpenAI's most sensitive assets. Key responsibilities will include:Key Responsibilities:Innovate and enhance our detection and response infrastructure to automate comprehensive workflows for detection and investigation.Develop, assess, and refine detection rules to guarantee effective and sustainable operations.Lead projects across OpenAI’s technology landscape focusing on insider threats, including access abuse and intellectual property theft, as well as emerging risks associated with AI infrastructure.Collaborate with cross-functional teams such as HR, Legal, and investigative units, providing technical insights and evidence to support thorough investigations.Engage in pioneering AI research initiatives, leveraging AI to bolster OpenAI’s security framework.Ideal Candidate Profile:A minimum of 5 years of experience in a detection/response or insider risk role; we welcome both mid-level and senior applicants.Proficient in operating systems and platforms, including macOS, Windows, Linux, and Kubernetes, with hands-on experience in cloud infrastructure.Strong knowledge of modern adversarial tactics, data exfiltration methods, and experience in managing and leading incident responses.Demonstrated proficiency in scripting languages such as Python, Bash, or PowerShell.Possess excellent analytical and problem-solving skills, with a keen attention to detail.

Join Sample Healthcare as a Founding Engineer!At Sample Healthcare, we are committed to transforming healthcare operations from a burden into a formidable competitive edge. Despite the USA's leadership in introducing new treatments, our healthcare professionals spend an alarming 73% of their time on administrative tasks. Our mission is to eliminate this inefficiency and pave the way for medical progress. We collaborate with top national healthcare providers and have amassed data from 75% of oncology clinics across the nation, with our network rapidly expanding.Why It MattersThe American healthcare system is facing urgent challenges as our population ages and chronic illnesses proliferate. Clinicians and administrators bear an increasing load, often within precariously thin margins. This administrative friction results in not only inefficiencies but also dangerous delays in diagnoses and treatment, leading to clinician burnout. To sustain America's role as a leader in modern medicine amidst accelerating scientific discovery, we must address these operational hurdles.Our Innovative ProductWe have developed a transformative platform that empowers healthcare providers to create AI copilots, automating and streamlining critical operations. These copilots enhance efficiency while continuously gathering valuable data that improves our models over time. By joining our network, providers collaborate with specialists to support patients effectively. Our astonishing growth trajectory—achieving Series A revenue metrics within just ten months—attests to our potential.Your OpportunityBe part of a generation-defining company. As a founding engineer, you will tackle some of the most significant challenges in healthcare, with the autonomy to innovate. Our engineering team is currently focused on:Developing frameworks and IDEs for AI-powered workflows, evolving from copilots to comprehensive assistants.Training advanced models for medical record reasoning.Creating pipelines that swiftly tune task-specific models based on data from our copilots.These challenges are not just technical—they are opportunities to redefine healthcare operations. Success hinges on navigating both technical and domain complexities.Who We're SeekingWe aim to build a world-class team of engineers who embody:Technical Excellence: Proficiency in software development and a passion for solving complex problems.Innovation Mindset: A drive to embrace new technologies and methodologies.Collaborative Spirit: A commitment to working effectively in a team-oriented environment.

About DepthFirst AIAt DepthFirst AI, we recognize that software underpins modern civilization, yet its vulnerabilities pose significant risks to integrity and security. Our mission is to enhance software security through innovative solutions.We are developing cutting-edge intelligence to identify and remediate critical software vulnerabilities, leveraging AI agents to discover zero-day vulnerabilities across extensive customer codebases and popular open-source software.Our founding team comprises industry leaders from DeepMind, Databricks, Square, and Faire, bringing unparalleled expertise in security and large language models (LLMs). We seek talented technical professionals eager to explore the intersection of AI, security, and infrastructure.Role Overview:We are looking for a skilled Research Engineer to contribute to the development and training of AI agents focused on vulnerability discovery and exploitation.Your work will be pivotal in creating technology capable of detecting vulnerabilities, akin to Log4J, at scale, ensuring the security of customer and open-source codebases.Ideal candidates will possess a strong engineering intuition, experience in model evaluation and benchmarks, with reinforcement learning experience being an added advantage. Your contributions will be instrumental in shaping a product that aims to revolutionize security practices for companies.Why You Will Love This Role:Develop Cutting-Edge AI pipelines tailored for the detection and exploitation of complex software vulnerabilities.Design and Maintain evaluation benchmarks that genuinely reflect the challenges faced by our users.Craft effective training methodologies and reinforcement learning environments for security coding agents.Be Part of a Solution to critical security challenges, with feedback from our valued customers revealing the immediate impact of our product.

About Our TeamAt OpenAI, our Security organization is dedicated to fostering safe and responsible innovation on a global scale. As our systems, infrastructure, and research capabilities expand, we are committed to investing in top-tier security measures that protect our people, products, and users while maintaining our momentum in progress.Our team is focused on safeguarding OpenAI’s environments by developing sophisticated detection systems, enhancing real-time response capabilities, scaling telemetry and logging infrastructure, and providing actionable threat intelligence to proactively counter adversaries.About the RoleWe are on the lookout for a Global Detection and Response Lead who will take ownership of and enhance OpenAI’s cybersecurity detection and response operations. In this pivotal role, you will establish the strategy and oversee the execution of security monitoring, incident response, recovery, and post-incident enhancements across our global infrastructure.As a hands-on leader with substantial technical credibility and acute operational instincts, you will build and mentor high-performing teams, collaborate closely with Infrastructure, Research, Product Security, Enterprise Security, IT, and Engineering to ensure that detection and response capabilities are integrated into the systems that drive OpenAI.This role demands strategic thinking combined with practical leadership skills, requiring deep technical expertise, operational discipline, and the ability to cultivate high-performing teams in a dynamic environment.Key Responsibilities:Lead global detection and response operations, ensuring continuous monitoring, triage, investigation, containment, and remediation of security incidents across diverse networks and infrastructures.Mentor and manage several teams of senior engineers focused on observability, detection and response, and threat intelligence, strategically expanding these functions as OpenAI’s computational capacity and platform aspirations grow.Ensure exceptional operational readiness through management of incident response playbooks, on-call procedures, escalation protocols, and ongoing enhancements to response efficacy and agility.Enhance detection effectiveness by collaborating with engineering teams to ensure essential telemetry is accessible, reliable, and actionable across cloud, corporate, and production environments.Work collaboratively across all departments to assess and address emerging security challenges and risks.

Join Cloudflare as a Threat Detection and Incident Response Intern for the Summer of 2026! This exciting opportunity is designed for students who are passionate about cybersecurity and eager to learn about detecting and responding to threats in a dynamic environment. You will work alongside experienced professionals, gaining hands-on experience that will enhance your skills and prepare you for a successful career in the field.

Embark on an exciting journey as a Threat Detection and Incident Response Intern at Cloudflare for the summer of 2026. This internship will provide you with the hands-on experience needed to thrive in the field of cybersecurity. You will work closely with our expert team to monitor, analyze, and respond to security incidents while contributing to innovative projects that protect our global network.

Join Cloudflare as a Senior Threat Intelligence Engineer, where you will play a pivotal role in enhancing our security posture by analyzing and mitigating cyber threats. You will collaborate closely with cross-functional teams to develop strategies that protect our global network and safeguard our customers' data. Your expertise will be essential in driving threat intelligence initiatives, ensuring that we remain ahead of emerging threats.

Join Cloudflare’s Solutions Engineering team as a Threat Advisory Engineer, where you will play a pivotal role in providing expert insights and strategies to help our clients navigate the complexities of cybersecurity threats. You will engage directly with clients to understand their unique challenges and deliver tailored solutions that enhance their security posture.Your contributions will be vital in building trust and confidence among our clients as we work together to combat evolving threats in the digital landscape.

Mercor is looking for a Software Engineer specializing in fraud detection. This full-time position is based in either San Francisco or New York City. The focus is on building and refining systems that protect both the company and its clients from fraudulent activity. Key responsibilities Design and develop tools to identify and reduce fraud across mercor’s platforms. Implement solutions that detect suspicious patterns and prevent threats before they escalate. Collaborate with colleagues from various disciplines to strengthen fraud detection strategies. Collaboration and technology This role requires regular interaction with engineering, product, and other internal teams. The work involves using modern technology to keep mercor’s systems secure and resilient.

About the TeamThe Applied team is dedicated to responsibly introducing OpenAI's groundbreaking technology to the global community. We have launched revolutionary products like ChatGPT, Plugins, DALL·E, and APIs for GPT-5, embeddings, and fine-tuning. Additionally, we manage extensive inference infrastructure to support our rapidly advancing initiatives.Our clients leverage our APIs to create dynamic businesses with innovative product features previously thought impossible. For instance, ChatGPT exemplifies the capabilities our technology currently offers. We prioritize the responsible use of our powerful tools, ensuring that safety remains paramount over unrestricted growth.The Fraud Engineering team operates within the Applied Engineering organization, focusing on identifying and mitigating fraudulent activities on our platform. We are seeking a software engineer with expertise in anti-fraud and abuse systems to help us design and implement next-generation solutions.About the RoleThe Scaled Abuse team safeguards OpenAI’s products and users by detecting, preventing, and addressing fraudulent and abusive activities on a large scale. We develop and maintain backend and data systems that facilitate real-time detection, investigative workflows, and enforcement, ensuring a balance between robust protection and an excellent user experience as our platform evolves.Our work lies at the convergence of engineering and abuse prevention expertise. We collaborate closely with Trust & Safety, Security, and Product teams to identify emerging attack trends, translate complex signals into actionable system behavior, and continuously enhance our defenses. We value engineers who can navigate unfamiliar codebases swiftly, develop a deep understanding of system functionality, and suggest practical improvements to enhance overall resilience.In This Role, You Will:Design and develop systems for fraud detection and remediation, balancing fraud loss, implementation costs, and customer experience.Collaborate with finance, security, product, research, and trust & safety teams to effectively combat fraudulent and abusive behaviors on our platform.Stay updated with the latest techniques and tools to remain ahead of determined adversaries.Utilize GPT-5 and future models to enhance our fraud and abuse mitigation efforts.You May Thrive in This Role If You:Possess at least 5 years of software engineering experience, particularly in backend and data systems.

Join Sofi as a Lead Cyber Threat Intelligence Engineer and play a pivotal role in safeguarding our digital landscape. In this position, you will lead initiatives aimed at identifying, analyzing, and mitigating potential cyber threats, ensuring the safety and integrity of our systems and data.

About CrunchyrollFounded by fans, Crunchyroll is dedicated to delivering the art and culture of anime to a vibrant community. Connecting over 100 million anime and manga enthusiasts across 200+ countries and territories, we create experiences that resonate, whether through online streaming, theatrical releases, games, merchandise, or events. Join us in shaping the future of anime!About the RoleAs a Senior Machine Learning Engineer focusing on Fraud Detection, you will collaborate with the Director of Data Science and Machine Learning within our Center for Data and Insights. This position can be based in either the Los Angeles or San Francisco area.Your expertise will drive the design and implementation of scalable machine learning models aimed at detecting account sharing fraud. Utilizing user behavior data such as geolocation, concurrent sessions, and device profiles, you will work closely with data scientists, product analysts, and data engineers to transform research prototypes into production systems that improve detection accuracy while minimizing user disruption. Your contributions will align with industry best practices, driving subscriber growth in our VOD streaming platform.Core Areas of ResponsibilityDesign and implement machine learning algorithms, including real-time anomaly detection models to identify unauthorized account sharing.Develop comprehensive ML pipelines for data preprocessing, model training, evaluation, and deployment leveraging cloud platforms.Optimize models for performance, scalability, and efficiency to accommodate high-volume streaming data.Integrate machine learning solutions with existing systems via APIs while establishing monitoring for model drift and retraining.Collaborate on A/B testing and iterative improvements to refine algorithms in response to evolving evasion tactics.

At Habitat Health, we aspire to create a future where seniors can enjoy a fulfilling and independent aging experience within their own homes, supported by comprehensive healthcare access. Our mission is to deliver personalized, coordinated clinical and social care, complemented by health plan coverage through the Program of All-Inclusive Care for the Elderly (“PACE”), in partnership with leading healthcare organizations, including Kaiser Permanente.We are committed to providing a fully integrated experience that fosters a sense of belonging for participants and their caregivers. Our dedicated care teams are engaged and empowered to offer personalized care both in our centers and at home. Additionally, we equip our partners with scalable solutions to effectively address the healthcare needs and financial challenges associated with aging populations.As Habitat Health continues to expand, we are on the lookout for passionate individuals eager to join our mission of transforming the aging experience. To learn more about us, visit https://www.habitathealth.com.

Join our dynamic Security Engineering team as a Senior Security Engineer specializing in Detection and Incident Response. In this pivotal role, you will blend the realms of security operations and software engineering, not only investigating incidents but also developing the systems that detect, contain, and prevent them. Your contributions will involve designing and deploying high-precision detection mechanisms across cloud services and enterprise SaaS platforms, crafting automation to expedite response times, and enhancing telemetry pipelines essential for robust security measures.Your expertise in coding will be as vital as your incident triaging skills. You will structure investigations, analyze root causes, and clearly communicate the implications of security incidents to both technical and non-technical stakeholders. Additionally, you'll leverage these insights to drive lasting engineering improvements, resulting in better detections and smarter automation.