Senior Data Scientist - Expert in NLP and LLM
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Experience Level
Senior
Qualifications
About Scismic
At Scismic, we are committed to fostering a vibrant and entrepreneurial atmosphere where talented individuals thrive on creativity. We celebrate inclusivity and strive to maintain an environment where every employee feels valued and heard. We do not tolerate any form of discrimination or harassment, and we are dedicated to building an organization that embraces diversity and inclusion.
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Scismic is proud to partner with a leading global consulting firm renowned for its collaborative and inclusive culture that nurtures creativity, growth, and innovation. With a dedicated team of over 1,000 professionals operating across 50 international markets, this organization collaborates with prestigious clients to tackle intricate business challenges spanning various industries. The company embraces a 'builder’s mindset,' empowering employees to devise innovative solutions, create a lasting impact, and advance their careers in a supportive environment.We are currently seeking a talented Senior Data Scientist who possesses extensive expertise in Natural Language Processing and Large Language Models to join our consulting practice. You will collaborate directly with Fortune 500 clients, leveraging cutting-edge AI technologies to address complex business challenges across diverse sectors.
Join Experian's Innovation Lab as a Senior Data Scientist, where you will leverage your expertise to drive cutting-edge analytics and data-driven decision-making within our dynamic team. In this fully remote role, you will collaborate with cross-functional teams to develop innovative solutions that enhance business operations and customer experiences.
Art of Problem Solving
At Art of Problem Solving (AoPS), we believe that data is a cornerstone of our innovative approach to designing, developing, and enhancing our educational products. We cater to a diverse community of students across the globe through our digital platforms that facilitate discovery, enrollment, learning, and sustained engagement. Our products generate comprehensive behavioral and operational data, which we leverage to make informed decisions that elevate student experiences. We are seeking a Senior Data Scientist to join us as an integral strategic partner within the Product team. This full-stack individual contributor role is ideal for someone who excels at defining key metrics, designing experiments, and addressing complex, high-stakes product inquiries. Your mission will be to enhance our product decision-making processes and bridge the gap between analytics and strategic direction. Collaborating closely with product leadership, engineers, and designers, you will help shape the direction of our products, assess trade-offs, and ensure we are crafting experiences that deliver genuine value to students and their families.
Art of Problem Solving
At Art of Problem Solving (AoPS), data is at the heart of our mission to engage and retain families across the globe. With a reach extending to tens of thousands of students, our marketing strategies encompass various channels, including acquisition, campaign performance, lifecycle engagement, brand awareness, and community growth. The insights we gain from these initiatives are only as valuable as the decisions they inform.We are seeking a skilled Data Scientist to join our Marketing and Growth teams as a vital analytical partner. This role is designed for a full-stack individual contributor adept at conducting in-depth analyses, creating customer segments, measuring attribution, designing experiments, and addressing complex, high-impact marketing questions. Your contributions will enhance our marketing and growth strategies, bridging the gap between analytics and strategic decision-making.In collaboration with our marketing and growth teams, you will help shape our marketing strategies, assess channel performance, and ensure we effectively reach and convert audiences with compelling messages that drive enrollment.
Ironflow
About Ironflow AIAt Ironflow, we are pioneering the first AI-native ERP tailored for defense technology — a groundbreaking system that thinks, reasons, and collaborates with the individuals responsible for building, safeguarding, and defending our way of life.We are not merely updating existing concepts with a modern interface. Instead, we are innovating from the ground up — redefining how software enhances operations at the forefront of the defense technology revolution. Our team comprises veterans, engineers, and operators who have firsthand experience with the challenges posed by outdated systems. Ironflow integrates natural language processing, intelligent agents, and practical rigor to provide the frontline with clarity and efficiency.If you are courageous, decisive, and driven by the desire to make a meaningful impact — we want you to join us. Here, curiosity meets purpose.Why This Role is EssentialAs the AI/LLM Integration Engineer, you will be at the core of Ironflow's technology. Your role will extend beyond simple prompt writing; you will shape the cognitive processes of our system. You will design the orchestration layer facilitating real-time chat, multi-agent collaboration, and backend execution throughout ERP workflows. Your contributions will influence how our software reasons, adapts, and engages with users — on a large scale and in real-time.
Veracyte, Inc.
About Veracyte Veracyte, Inc. is dedicated to transforming cancer care and improving patient outcomes around the world. The team works in a mission-driven environment, supporting clinicians with innovative solutions and quality insights that help guide life-changing decisions. Employees are encouraged to make a real impact and grow in a collaborative setting known as the Veracyte way. Core Values We Seek A Better Way: Innovating boldly, learning from challenges, and showing resilience to enhance cancer care. We Make It Happen: Acting with urgency, aiming for excellence, and bringing joy to hard work. We Are Stronger Together: Collaborating openly, seeking understanding, and celebrating shared achievements. We Care Deeply: Valuing differences, maintaining integrity, and supporting each other. Role Overview The Senior Bioimage Scientist will join the Discovery Research team, focusing on tissue-based oncology diagnostics. This position connects pathologists, biologists, and AI/ML teams, contributing to the development of new assays, digital pathology AI tools, biological interpretation, and diagnostic product advancement. Both wet and dry lab work are part of the role, including developing, optimizing, and validating imaging assays and quantitative image analysis. The goal is to link biological and clinical questions with clear, interpretable image-derived metrics and features. Location San Diego, California (Hybrid)
AbbVie Inc.
Join AbbVie as a Senior Scientist II in Analytical Development, where your expertise will contribute to innovative solutions in biopharmaceuticals. You will collaborate with a dynamic team, leveraging your analytical skills to drive research and development efforts. This role is pivotal in advancing our mission to improve patient outcomes through groundbreaking therapies.
Oura Health Ltd.
Join Oura Health as a Senior Algorithm Scientist and play a pivotal role in advancing our innovative health technology. In this position, you will leverage your expertise in algorithm development to enhance our cutting-edge solutions that empower users to optimize their health and wellness. Collaborate with a dynamic team of engineers and scientists to design, implement, and validate algorithms that will shape the future of personal health tracking.
Becton, Dickinson and Company
Join Our Mission to Advance Global Health!Becton, Dickinson and Company (BD) is a leading global medical technology company dedicated to advancing the world of health. We strive to enhance medical discovery, diagnostics, and the delivery of care. With over 65,000 employees across the globe, we are committed to tackling some of the most pressing health challenges worldwide. As the Health Economics and Outcomes Research Lead, you will report to the Director of Scientific Affairs & Clinical Evidence within our Medical Affairs team. In this critical role, you will be tasked with developing and executing agile HEOR strategies in collaboration with both global and regional teams. Your expertise will drive impactful research and ultimately improve patient outcomes.
Veracyte, Inc.
Join Veracyte, a leader in transforming cancer care through innovative diagnostics that empower patients and clinicians alike. At Veracyte, we provide an inspiring work environment where you can make a significant impact on patients' lives while advancing your career. Our culture, known as the Veracyte way, emphasizes collaboration, resilience, and a commitment to excellence.Our Core Values:We Seek A Better Way: We boldly innovate and learn from challenges to improve cancer care.We Make It Happen: We prioritize urgency, quality, and enjoyment in our work.We Are Stronger Together: We foster open collaboration and celebrate our collective successes.We Care Deeply: We honor our diverse backgrounds and support each other in doing what is right.The Role:We are on the lookout for an enthusiastic Bioinformatics Research Scientist to join our Translational Bioinformatics group within the Bioinformatics and Data Science Team. This pivotal role involves leveraging computational and statistical techniques on extensive transcriptomic and genomic datasets, particularly focusing on prostate cancer biology and its clinical implications. The ideal candidate will play a key role in identifying clinically relevant molecular signatures that enhance disease stratification, prognosis, and the development of diagnostics, while effectively communicating findings to both scientific and clinical audiences. This position offers a unique opportunity to bridge the realms of data science, biology, and clinical research through close collaboration with scientists, clinicians, and cross-functional teams to convert complex data into actionable insights.
Genesis Molecular AI
Genesis Molecular AI is on a mission to transform drug discovery through innovative computational chemistry solutions. We are building a premier team of experts in computational chemistry, and we invite you to join us as a Senior CADD Scientist. In this pivotal role, you will collaborate closely with our cutting-edge wet lab scientists and work alongside our distributed computational chemistry and CADD science teams throughout the United States.Key Responsibilities:Employ a blend of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a varied target landscape, including innovative targets with limited chemical precedents.Implement methodologies such as virtual screening, molecular simulation, and potency and ADMET prediction to facilitate critical decision-making processes in drug discovery.Work collaboratively with medicinal chemists to design molecules and develop tailored computational strategies for specific projects.Serve as a bridge among teams, effectively communicating between our computational chemistry and medicinal chemistry groups to promote seamless information exchange and collaborative decision-making.Thrive in a dynamic environment that encourages innovation and rapid iteration.
Join Veracyte as a Senior Computational Development Scientist, where you will play a pivotal role in our mission to transform patient care through innovative genomics. In this remote position, you will leverage cutting-edge computational techniques to analyze complex genomic data, contributing to groundbreaking discoveries in cancer diagnostics.
Iambic Therapeutics
JOB SUMMARYIambic Therapeutics is on the lookout for a talented and highly motivated Senior/Principal Scientist specializing in Computational Chemistry to join our innovative Computational Sciences team at our San Diego headquarters. As a vital contributor, you will leverage advanced ligand and structure-based methodologies to propel our drug discovery initiatives. You will actively engage with research teams focused on developing groundbreaking therapeutics across various indications. Collaborating closely with experts in machine learning, medicinal chemistry, and biology, you will implement state-of-the-art Structure-Based Drug Design (SBDD) techniques throughout hit identification, lead optimization, and candidate selection phases. This hands-on position demands robust expertise in computational chemistry, a keen interest in co-folding applications, and a proactive drug-hunter mindset.KEY RESPONSIBILITIESUtilize diverse ligand and structure-based strategies during the hit identification, lead optimization, and candidate selection phases (including cheminformatics, pharmacophore modeling, docking, shape-based virtual screening, de novo molecular design, and molecular dynamics simulations).Lead design cycles by identifying structure-activity relationships and integrating computational predictions with bioactivity data.Collaborate with medicinal chemists to design, assess, and prioritize virtual libraries, proposing concrete molecular designs.Work alongside machine learning scientists to meld SBDD methodologies with our proprietary transformer-based property prediction technology (Enchant).Enhance and utilize our proprietary protein-ligand co-folding technology (NeuralPLexer) to generate novel and actionable structural hypotheses.Translate scientific inquiries into computational workflows, delivering actionable insights.Present findings to project teams, elucidating methods, implications, and recommendations.Develop, validate, and maintain computational workflows and tools.QUALIFICATIONSRequired:PhD or equivalent in Computational Chemistry (or a related field) with a minimum of 5 years of experience in an industrial drug discovery setting.Proven experience in supporting active small molecule drug discovery programs.Experience with ligand and structure-based drug design methodologies.
Iambic Therapeutics
Job SummaryIambic Therapeutics is looking for an exceptional and driven Senior Associate Scientist to enhance our Chemistry team at our San Diego headquarters. This exciting position allows you to thrive in a vibrant, cross-disciplinary environment, where you will collaborate closely with medicinal chemists, biologists, DMPK scientists, computational chemists, machine learning experts, and software engineers. You will engage in every phase of the discovery process, from hit identification and lead optimization to candidate selection. This role is laboratory-focused and demands robust technical skills in organic synthesis, catalysis, and medicinal chemistry, alongside hands-on experience in the drug discovery process and a proven “drug hunter” mentality.Key ResponsibilitiesDesign, synthesize, purify, and characterize chemical compounds (10 mg–5 g scale) utilizing cutting-edge analytical techniques including LCMS, HPLC, and NMR, implementing both manual and automated parallel synthesis techniques.Identify and optimize reaction conditions through the use of screening kits and other efficient methodologies.Collaborate with the high-throughput experimentation team to guarantee successful execution of parallel chemistry experiments.Analyze biological and ADME-PK data using cheminformatics tools and contribute to data-driven discussions and strategic planning.Work alongside computational chemists to harness machine learning insights for the effective execution of the design–make–test cycle and platform development.Present findings to project teams and senior leadership, effectively communicating data, implications, and recommendations.QualificationsBS in Chemistry with 5+ years of experience in the pharmaceutical or biotechnology sector, or MS in Chemistry with 3+ years of relevant experience.Demonstrated expertise in multi-step organic synthesis, reaction optimization, Structure-Activity Relationship (SAR) analysis, and effective scientific presentation skills.Adeptness in a fast-paced, highly collaborative research atmosphere.Willingness to work onsite in San Diego.Preferred QualificationsExperience in high-throughput experimentation is advantageous.Familiarity with ADME-PK principles is a plus.5+ years of experience contributing to drug discovery projects is preferred.
Integrated Resources, Inc.
Job Overview: We are seeking a dedicated Bench Scientist II to join our dynamic team in San Diego. This role entails collaborating with fellow scientists to advance translational pharmacology research focusing on various clinical candidate compounds and late-stage assets. Key responsibilities include performing tissue culture, conducting cell-based assays, and executing western blot analysis. The ideal candidate will possess a solid background in cancer biology and relevant laboratory experience while demonstrating strong communication and teamwork skills.Key Responsibilities: Conduct tissue culture, cell-based assays, and western blot analysisWork with unscreened blood, human tissue, or human cell lines
California Creative Solutions Inc.
Join our dynamic team at California Creative Solutions Inc. as a Senior Manager of Data Management in the Pharmaceuticals sector. This full-time role is based in beautiful San Diego and is pivotal in ensuring the integrity and quality of clinical data management for our innovative projects.As a Senior Manager, you will lead the Data Management team, overseeing the design, testing, and implementation of clinical data collection studies. Your expertise will be crucial in managing high-quality data deliverables for regulatory submissions, publications, and due diligence activities in collaboration with Contract Research Organizations (CROs).Key Responsibilities:Collaborate in designing and implementing clinical protocols and data collection systems.Develop and uphold data quality plans.Ensure timely execution of data management timelines for assigned projects.Provide strategic input into protocol designs with a focus on data management.Assist Biostatistics in the evaluation of Statistical Analysis Plans.Identify and resolve data discrepancies using standardized validation systems.Oversee the generation of quality data deliverables for regulatory, publication, and due diligence purposes.Participate in reviewing clinical and regulatory documents to maintain data integrity and quality.Manage projects in collaboration with CROs and lead internal project initiatives.Contribute to the development of standards and process documentation, including SOPs and Work Instructions.Support compliance with industry quality standards and guidelines.Assist in selecting, developing, and evaluating personnel to ensure efficient operations.Engage in the corporate and departmental budget processes and management.Facilitate career development for Data Management personnel.Perform additional duties as required.
Genesis Molecular AI
At Genesis Molecular AI, we are creating an elite team of experts in computational chemistry to transform the landscape of drug discovery through advanced machine learning and biophysical simulations. We invite a Senior Computational Aided Drug Discovery (CADD) Scientist to join us in our mission, collaborating closely with scientists in our advanced wet lab and our distributed teams in computational chemistry across the United States.Key ResponsibilitiesEmploy a mix of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a diverse array of targets, including innovative targets with limited chemical history.Utilize techniques such as virtual screening, molecular simulations, and ADMET prediction to facilitate critical decision-making during drug discovery.Work closely with medicinal chemists on molecular design and the creation of tailored computational methodologies for specific projects.Serve as a liaison across teams, effectively bridging communication between our computational and medicinal chemistry departments to ensure smooth information exchange and collaborative strategies.Thrive in a fast-paced environment that encourages innovation and rapid iteration.QualificationsPhD in Computational Chemistry, Structural Biology, or a related discipline. Candidates with a PhD in organic or medicinal chemistry and substantial laboratory experience transitioning into industry roles in CADD are also encouraged to apply.Extensive knowledge of structure-based drug design and protein-ligand interactions.Expertise in using industry-standard CADD tools, including MOE, PyMOL, and Schrodinger Suite.A minimum of 2 years of experience in the pharmaceutical or biotech industry as a CADD scientist, with practical involvement in active drug discovery projects.While onsite presence at our San Diego lab is preferred for collaboration, we are open to considering remote team members as well.What We OfferAttractive SalaryComprehensive Health Care Plans (Medical, Dental, and Vision fully covered for employees)An opportunity to work in a pioneering environment with the latest technologies in drug discovery.
Bee Genius
At Bee Genius, we are pioneering the future of work, today.This post was generated on behalf of our client:Job Description: We are seeking a highly accomplished and motivated Principal Scientist to become an integral part of our innovative team. In this role, you will spearhead groundbreaking scientific research and development initiatives, offer expert technical guidance, and catalyze innovation within our organization.Responsibilities:Lead and oversee scientific research projects from conception through to execution.Design and refine scientific methodologies and protocols for optimal outcomes.Conduct thorough analysis and interpretation of intricate data, effectively presenting insights to stakeholders.Mentor and provide technical support to junior scientists, fostering their professional growth.Collaborate with cross-functional teams to convert scientific discoveries into actionable applications.Remain abreast of the latest advancements and industry trends in your field.
AbbVie is seeking a highly skilled Principal Research Scientist II specializing in Lipid Chemistry to join our innovative team in San Diego. This role is pivotal in advancing our research efforts and driving the development of novel lipid-based therapies. The ideal candidate will possess a robust background in lipid biochemistry, with a proven track record of impactful research and development.
Veracyte
Join Veracyte, a trailblazer in transforming cancer care on a global scale. Our team is dedicated to making a profound impact on patient lives while fostering an environment of continuous learning and growth. We embody the Veracyte way, a collaborative spirit driven by our core values to equip clinicians with the critical insights necessary for impactful patient decisions.Our Core Values:We Seek A Better Way: Innovating with courage, learning from challenges, and resiliently pursuing advancements in cancer care.We Make It Happen: Acting with urgency and dedication to quality while finding joy in our endeavors.We Are Stronger Together: Fostering open collaboration, understanding, and celebrating our collective successes.We Care Deeply: Valuing our differences, committing to integrity, and supporting one another. The Role:We are in search of a skilled Bioinformatics Scientist to enhance our Sustaining and Continuous Improvement team within Global Operations. This pivotal role involves constructing, refining, and supervising comprehensive quality control (QC) processes for RNA-based microarray and NGS high-volume Laboratory Developed Test (LDT) diagnostic products in CLIA labs. The Bioinformatics Scientist will ensure operational excellence, drive process enhancements, and collaborate with cross-functional teams for effective troubleshooting. The selected candidate will maintain product consistency through routine CLIA updates, contribute to verification and validation documentation, and engage in design reviews. This role promises valuable exposure to diagnostic product development and sustainability, with a direct impact on improving patient outcomes.
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Scismic is proud to partner with a leading global consulting firm renowned for its collaborative and inclusive culture that nurtures creativity, growth, and innovation. With a dedicated team of over 1,000 professionals operating across 50 international markets, this organization collaborates with prestigious clients to tackle intricate business challenges spanning various industries. The company embraces a 'builder’s mindset,' empowering employees to devise innovative solutions, create a lasting impact, and advance their careers in a supportive environment.We are currently seeking a talented Senior Data Scientist who possesses extensive expertise in Natural Language Processing and Large Language Models to join our consulting practice. You will collaborate directly with Fortune 500 clients, leveraging cutting-edge AI technologies to address complex business challenges across diverse sectors.
Join Experian's Innovation Lab as a Senior Data Scientist, where you will leverage your expertise to drive cutting-edge analytics and data-driven decision-making within our dynamic team. In this fully remote role, you will collaborate with cross-functional teams to develop innovative solutions that enhance business operations and customer experiences.
Art of Problem Solving
At Art of Problem Solving (AoPS), we believe that data is a cornerstone of our innovative approach to designing, developing, and enhancing our educational products. We cater to a diverse community of students across the globe through our digital platforms that facilitate discovery, enrollment, learning, and sustained engagement. Our products generate comprehensive behavioral and operational data, which we leverage to make informed decisions that elevate student experiences. We are seeking a Senior Data Scientist to join us as an integral strategic partner within the Product team. This full-stack individual contributor role is ideal for someone who excels at defining key metrics, designing experiments, and addressing complex, high-stakes product inquiries. Your mission will be to enhance our product decision-making processes and bridge the gap between analytics and strategic direction. Collaborating closely with product leadership, engineers, and designers, you will help shape the direction of our products, assess trade-offs, and ensure we are crafting experiences that deliver genuine value to students and their families.
Art of Problem Solving
At Art of Problem Solving (AoPS), data is at the heart of our mission to engage and retain families across the globe. With a reach extending to tens of thousands of students, our marketing strategies encompass various channels, including acquisition, campaign performance, lifecycle engagement, brand awareness, and community growth. The insights we gain from these initiatives are only as valuable as the decisions they inform.We are seeking a skilled Data Scientist to join our Marketing and Growth teams as a vital analytical partner. This role is designed for a full-stack individual contributor adept at conducting in-depth analyses, creating customer segments, measuring attribution, designing experiments, and addressing complex, high-impact marketing questions. Your contributions will enhance our marketing and growth strategies, bridging the gap between analytics and strategic decision-making.In collaboration with our marketing and growth teams, you will help shape our marketing strategies, assess channel performance, and ensure we effectively reach and convert audiences with compelling messages that drive enrollment.
Ironflow
About Ironflow AIAt Ironflow, we are pioneering the first AI-native ERP tailored for defense technology — a groundbreaking system that thinks, reasons, and collaborates with the individuals responsible for building, safeguarding, and defending our way of life.We are not merely updating existing concepts with a modern interface. Instead, we are innovating from the ground up — redefining how software enhances operations at the forefront of the defense technology revolution. Our team comprises veterans, engineers, and operators who have firsthand experience with the challenges posed by outdated systems. Ironflow integrates natural language processing, intelligent agents, and practical rigor to provide the frontline with clarity and efficiency.If you are courageous, decisive, and driven by the desire to make a meaningful impact — we want you to join us. Here, curiosity meets purpose.Why This Role is EssentialAs the AI/LLM Integration Engineer, you will be at the core of Ironflow's technology. Your role will extend beyond simple prompt writing; you will shape the cognitive processes of our system. You will design the orchestration layer facilitating real-time chat, multi-agent collaboration, and backend execution throughout ERP workflows. Your contributions will influence how our software reasons, adapts, and engages with users — on a large scale and in real-time.
Veracyte, Inc.
About Veracyte Veracyte, Inc. is dedicated to transforming cancer care and improving patient outcomes around the world. The team works in a mission-driven environment, supporting clinicians with innovative solutions and quality insights that help guide life-changing decisions. Employees are encouraged to make a real impact and grow in a collaborative setting known as the Veracyte way. Core Values We Seek A Better Way: Innovating boldly, learning from challenges, and showing resilience to enhance cancer care. We Make It Happen: Acting with urgency, aiming for excellence, and bringing joy to hard work. We Are Stronger Together: Collaborating openly, seeking understanding, and celebrating shared achievements. We Care Deeply: Valuing differences, maintaining integrity, and supporting each other. Role Overview The Senior Bioimage Scientist will join the Discovery Research team, focusing on tissue-based oncology diagnostics. This position connects pathologists, biologists, and AI/ML teams, contributing to the development of new assays, digital pathology AI tools, biological interpretation, and diagnostic product advancement. Both wet and dry lab work are part of the role, including developing, optimizing, and validating imaging assays and quantitative image analysis. The goal is to link biological and clinical questions with clear, interpretable image-derived metrics and features. Location San Diego, California (Hybrid)
AbbVie Inc.
Join AbbVie as a Senior Scientist II in Analytical Development, where your expertise will contribute to innovative solutions in biopharmaceuticals. You will collaborate with a dynamic team, leveraging your analytical skills to drive research and development efforts. This role is pivotal in advancing our mission to improve patient outcomes through groundbreaking therapies.
Oura Health Ltd.
Join Oura Health as a Senior Algorithm Scientist and play a pivotal role in advancing our innovative health technology. In this position, you will leverage your expertise in algorithm development to enhance our cutting-edge solutions that empower users to optimize their health and wellness. Collaborate with a dynamic team of engineers and scientists to design, implement, and validate algorithms that will shape the future of personal health tracking.
Becton, Dickinson and Company
Join Our Mission to Advance Global Health!Becton, Dickinson and Company (BD) is a leading global medical technology company dedicated to advancing the world of health. We strive to enhance medical discovery, diagnostics, and the delivery of care. With over 65,000 employees across the globe, we are committed to tackling some of the most pressing health challenges worldwide. As the Health Economics and Outcomes Research Lead, you will report to the Director of Scientific Affairs & Clinical Evidence within our Medical Affairs team. In this critical role, you will be tasked with developing and executing agile HEOR strategies in collaboration with both global and regional teams. Your expertise will drive impactful research and ultimately improve patient outcomes.
Veracyte, Inc.
Join Veracyte, a leader in transforming cancer care through innovative diagnostics that empower patients and clinicians alike. At Veracyte, we provide an inspiring work environment where you can make a significant impact on patients' lives while advancing your career. Our culture, known as the Veracyte way, emphasizes collaboration, resilience, and a commitment to excellence.Our Core Values:We Seek A Better Way: We boldly innovate and learn from challenges to improve cancer care.We Make It Happen: We prioritize urgency, quality, and enjoyment in our work.We Are Stronger Together: We foster open collaboration and celebrate our collective successes.We Care Deeply: We honor our diverse backgrounds and support each other in doing what is right.The Role:We are on the lookout for an enthusiastic Bioinformatics Research Scientist to join our Translational Bioinformatics group within the Bioinformatics and Data Science Team. This pivotal role involves leveraging computational and statistical techniques on extensive transcriptomic and genomic datasets, particularly focusing on prostate cancer biology and its clinical implications. The ideal candidate will play a key role in identifying clinically relevant molecular signatures that enhance disease stratification, prognosis, and the development of diagnostics, while effectively communicating findings to both scientific and clinical audiences. This position offers a unique opportunity to bridge the realms of data science, biology, and clinical research through close collaboration with scientists, clinicians, and cross-functional teams to convert complex data into actionable insights.
Genesis Molecular AI
Genesis Molecular AI is on a mission to transform drug discovery through innovative computational chemistry solutions. We are building a premier team of experts in computational chemistry, and we invite you to join us as a Senior CADD Scientist. In this pivotal role, you will collaborate closely with our cutting-edge wet lab scientists and work alongside our distributed computational chemistry and CADD science teams throughout the United States.Key Responsibilities:Employ a blend of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a varied target landscape, including innovative targets with limited chemical precedents.Implement methodologies such as virtual screening, molecular simulation, and potency and ADMET prediction to facilitate critical decision-making processes in drug discovery.Work collaboratively with medicinal chemists to design molecules and develop tailored computational strategies for specific projects.Serve as a bridge among teams, effectively communicating between our computational chemistry and medicinal chemistry groups to promote seamless information exchange and collaborative decision-making.Thrive in a dynamic environment that encourages innovation and rapid iteration.
Join Veracyte as a Senior Computational Development Scientist, where you will play a pivotal role in our mission to transform patient care through innovative genomics. In this remote position, you will leverage cutting-edge computational techniques to analyze complex genomic data, contributing to groundbreaking discoveries in cancer diagnostics.
Iambic Therapeutics
JOB SUMMARYIambic Therapeutics is on the lookout for a talented and highly motivated Senior/Principal Scientist specializing in Computational Chemistry to join our innovative Computational Sciences team at our San Diego headquarters. As a vital contributor, you will leverage advanced ligand and structure-based methodologies to propel our drug discovery initiatives. You will actively engage with research teams focused on developing groundbreaking therapeutics across various indications. Collaborating closely with experts in machine learning, medicinal chemistry, and biology, you will implement state-of-the-art Structure-Based Drug Design (SBDD) techniques throughout hit identification, lead optimization, and candidate selection phases. This hands-on position demands robust expertise in computational chemistry, a keen interest in co-folding applications, and a proactive drug-hunter mindset.KEY RESPONSIBILITIESUtilize diverse ligand and structure-based strategies during the hit identification, lead optimization, and candidate selection phases (including cheminformatics, pharmacophore modeling, docking, shape-based virtual screening, de novo molecular design, and molecular dynamics simulations).Lead design cycles by identifying structure-activity relationships and integrating computational predictions with bioactivity data.Collaborate with medicinal chemists to design, assess, and prioritize virtual libraries, proposing concrete molecular designs.Work alongside machine learning scientists to meld SBDD methodologies with our proprietary transformer-based property prediction technology (Enchant).Enhance and utilize our proprietary protein-ligand co-folding technology (NeuralPLexer) to generate novel and actionable structural hypotheses.Translate scientific inquiries into computational workflows, delivering actionable insights.Present findings to project teams, elucidating methods, implications, and recommendations.Develop, validate, and maintain computational workflows and tools.QUALIFICATIONSRequired:PhD or equivalent in Computational Chemistry (or a related field) with a minimum of 5 years of experience in an industrial drug discovery setting.Proven experience in supporting active small molecule drug discovery programs.Experience with ligand and structure-based drug design methodologies.
Iambic Therapeutics
Job SummaryIambic Therapeutics is looking for an exceptional and driven Senior Associate Scientist to enhance our Chemistry team at our San Diego headquarters. This exciting position allows you to thrive in a vibrant, cross-disciplinary environment, where you will collaborate closely with medicinal chemists, biologists, DMPK scientists, computational chemists, machine learning experts, and software engineers. You will engage in every phase of the discovery process, from hit identification and lead optimization to candidate selection. This role is laboratory-focused and demands robust technical skills in organic synthesis, catalysis, and medicinal chemistry, alongside hands-on experience in the drug discovery process and a proven “drug hunter” mentality.Key ResponsibilitiesDesign, synthesize, purify, and characterize chemical compounds (10 mg–5 g scale) utilizing cutting-edge analytical techniques including LCMS, HPLC, and NMR, implementing both manual and automated parallel synthesis techniques.Identify and optimize reaction conditions through the use of screening kits and other efficient methodologies.Collaborate with the high-throughput experimentation team to guarantee successful execution of parallel chemistry experiments.Analyze biological and ADME-PK data using cheminformatics tools and contribute to data-driven discussions and strategic planning.Work alongside computational chemists to harness machine learning insights for the effective execution of the design–make–test cycle and platform development.Present findings to project teams and senior leadership, effectively communicating data, implications, and recommendations.QualificationsBS in Chemistry with 5+ years of experience in the pharmaceutical or biotechnology sector, or MS in Chemistry with 3+ years of relevant experience.Demonstrated expertise in multi-step organic synthesis, reaction optimization, Structure-Activity Relationship (SAR) analysis, and effective scientific presentation skills.Adeptness in a fast-paced, highly collaborative research atmosphere.Willingness to work onsite in San Diego.Preferred QualificationsExperience in high-throughput experimentation is advantageous.Familiarity with ADME-PK principles is a plus.5+ years of experience contributing to drug discovery projects is preferred.
Integrated Resources, Inc.
Job Overview: We are seeking a dedicated Bench Scientist II to join our dynamic team in San Diego. This role entails collaborating with fellow scientists to advance translational pharmacology research focusing on various clinical candidate compounds and late-stage assets. Key responsibilities include performing tissue culture, conducting cell-based assays, and executing western blot analysis. The ideal candidate will possess a solid background in cancer biology and relevant laboratory experience while demonstrating strong communication and teamwork skills.Key Responsibilities: Conduct tissue culture, cell-based assays, and western blot analysisWork with unscreened blood, human tissue, or human cell lines
California Creative Solutions Inc.
Join our dynamic team at California Creative Solutions Inc. as a Senior Manager of Data Management in the Pharmaceuticals sector. This full-time role is based in beautiful San Diego and is pivotal in ensuring the integrity and quality of clinical data management for our innovative projects.As a Senior Manager, you will lead the Data Management team, overseeing the design, testing, and implementation of clinical data collection studies. Your expertise will be crucial in managing high-quality data deliverables for regulatory submissions, publications, and due diligence activities in collaboration with Contract Research Organizations (CROs).Key Responsibilities:Collaborate in designing and implementing clinical protocols and data collection systems.Develop and uphold data quality plans.Ensure timely execution of data management timelines for assigned projects.Provide strategic input into protocol designs with a focus on data management.Assist Biostatistics in the evaluation of Statistical Analysis Plans.Identify and resolve data discrepancies using standardized validation systems.Oversee the generation of quality data deliverables for regulatory, publication, and due diligence purposes.Participate in reviewing clinical and regulatory documents to maintain data integrity and quality.Manage projects in collaboration with CROs and lead internal project initiatives.Contribute to the development of standards and process documentation, including SOPs and Work Instructions.Support compliance with industry quality standards and guidelines.Assist in selecting, developing, and evaluating personnel to ensure efficient operations.Engage in the corporate and departmental budget processes and management.Facilitate career development for Data Management personnel.Perform additional duties as required.
Genesis Molecular AI
At Genesis Molecular AI, we are creating an elite team of experts in computational chemistry to transform the landscape of drug discovery through advanced machine learning and biophysical simulations. We invite a Senior Computational Aided Drug Discovery (CADD) Scientist to join us in our mission, collaborating closely with scientists in our advanced wet lab and our distributed teams in computational chemistry across the United States.Key ResponsibilitiesEmploy a mix of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a diverse array of targets, including innovative targets with limited chemical history.Utilize techniques such as virtual screening, molecular simulations, and ADMET prediction to facilitate critical decision-making during drug discovery.Work closely with medicinal chemists on molecular design and the creation of tailored computational methodologies for specific projects.Serve as a liaison across teams, effectively bridging communication between our computational and medicinal chemistry departments to ensure smooth information exchange and collaborative strategies.Thrive in a fast-paced environment that encourages innovation and rapid iteration.QualificationsPhD in Computational Chemistry, Structural Biology, or a related discipline. Candidates with a PhD in organic or medicinal chemistry and substantial laboratory experience transitioning into industry roles in CADD are also encouraged to apply.Extensive knowledge of structure-based drug design and protein-ligand interactions.Expertise in using industry-standard CADD tools, including MOE, PyMOL, and Schrodinger Suite.A minimum of 2 years of experience in the pharmaceutical or biotech industry as a CADD scientist, with practical involvement in active drug discovery projects.While onsite presence at our San Diego lab is preferred for collaboration, we are open to considering remote team members as well.What We OfferAttractive SalaryComprehensive Health Care Plans (Medical, Dental, and Vision fully covered for employees)An opportunity to work in a pioneering environment with the latest technologies in drug discovery.
Bee Genius
At Bee Genius, we are pioneering the future of work, today.This post was generated on behalf of our client:Job Description: We are seeking a highly accomplished and motivated Principal Scientist to become an integral part of our innovative team. In this role, you will spearhead groundbreaking scientific research and development initiatives, offer expert technical guidance, and catalyze innovation within our organization.Responsibilities:Lead and oversee scientific research projects from conception through to execution.Design and refine scientific methodologies and protocols for optimal outcomes.Conduct thorough analysis and interpretation of intricate data, effectively presenting insights to stakeholders.Mentor and provide technical support to junior scientists, fostering their professional growth.Collaborate with cross-functional teams to convert scientific discoveries into actionable applications.Remain abreast of the latest advancements and industry trends in your field.
AbbVie is seeking a highly skilled Principal Research Scientist II specializing in Lipid Chemistry to join our innovative team in San Diego. This role is pivotal in advancing our research efforts and driving the development of novel lipid-based therapies. The ideal candidate will possess a robust background in lipid biochemistry, with a proven track record of impactful research and development.
Veracyte
Join Veracyte, a trailblazer in transforming cancer care on a global scale. Our team is dedicated to making a profound impact on patient lives while fostering an environment of continuous learning and growth. We embody the Veracyte way, a collaborative spirit driven by our core values to equip clinicians with the critical insights necessary for impactful patient decisions.Our Core Values:We Seek A Better Way: Innovating with courage, learning from challenges, and resiliently pursuing advancements in cancer care.We Make It Happen: Acting with urgency and dedication to quality while finding joy in our endeavors.We Are Stronger Together: Fostering open collaboration, understanding, and celebrating our collective successes.We Care Deeply: Valuing our differences, committing to integrity, and supporting one another. The Role:We are in search of a skilled Bioinformatics Scientist to enhance our Sustaining and Continuous Improvement team within Global Operations. This pivotal role involves constructing, refining, and supervising comprehensive quality control (QC) processes for RNA-based microarray and NGS high-volume Laboratory Developed Test (LDT) diagnostic products in CLIA labs. The Bioinformatics Scientist will ensure operational excellence, drive process enhancements, and collaborate with cross-functional teams for effective troubleshooting. The selected candidate will maintain product consistency through routine CLIA updates, contribute to verification and validation documentation, and engage in design reviews. This role promises valuable exposure to diagnostic product development and sustainability, with a direct impact on improving patient outcomes.
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