Senior Computational Development Scientist

Join Veracyte as a Senior Computational Development Scientist, where you will play a pivotal role in our mission to transform patient care through innovative genomics. In this remote position, you will leverage cutting-edge computational techniques to analyze complex genomic data, contributing to groundbreaking discoveries in cancer diagnostics.

JOB SUMMARYIambic Therapeutics is on the lookout for a talented and highly motivated Senior/Principal Scientist specializing in Computational Chemistry to join our innovative Computational Sciences team at our San Diego headquarters. As a vital contributor, you will leverage advanced ligand and structure-based methodologies to propel our drug discovery initiatives. You will actively engage with research teams focused on developing groundbreaking therapeutics across various indications. Collaborating closely with experts in machine learning, medicinal chemistry, and biology, you will implement state-of-the-art Structure-Based Drug Design (SBDD) techniques throughout hit identification, lead optimization, and candidate selection phases. This hands-on position demands robust expertise in computational chemistry, a keen interest in co-folding applications, and a proactive drug-hunter mindset.KEY RESPONSIBILITIESUtilize diverse ligand and structure-based strategies during the hit identification, lead optimization, and candidate selection phases (including cheminformatics, pharmacophore modeling, docking, shape-based virtual screening, de novo molecular design, and molecular dynamics simulations).Lead design cycles by identifying structure-activity relationships and integrating computational predictions with bioactivity data.Collaborate with medicinal chemists to design, assess, and prioritize virtual libraries, proposing concrete molecular designs.Work alongside machine learning scientists to meld SBDD methodologies with our proprietary transformer-based property prediction technology (Enchant).Enhance and utilize our proprietary protein-ligand co-folding technology (NeuralPLexer) to generate novel and actionable structural hypotheses.Translate scientific inquiries into computational workflows, delivering actionable insights.Present findings to project teams, elucidating methods, implications, and recommendations.Develop, validate, and maintain computational workflows and tools.QUALIFICATIONSRequired:PhD or equivalent in Computational Chemistry (or a related field) with a minimum of 5 years of experience in an industrial drug discovery setting.Proven experience in supporting active small molecule drug discovery programs.Experience with ligand and structure-based drug design methodologies.

At Genesis Molecular AI, we are creating an elite team of experts in computational chemistry to transform the landscape of drug discovery through advanced machine learning and biophysical simulations. We invite a Senior Computational Aided Drug Discovery (CADD) Scientist to join us in our mission, collaborating closely with scientists in our advanced wet lab and our distributed teams in computational chemistry across the United States.Key ResponsibilitiesEmploy a mix of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a diverse array of targets, including innovative targets with limited chemical history.Utilize techniques such as virtual screening, molecular simulations, and ADMET prediction to facilitate critical decision-making during drug discovery.Work closely with medicinal chemists on molecular design and the creation of tailored computational methodologies for specific projects.Serve as a liaison across teams, effectively bridging communication between our computational and medicinal chemistry departments to ensure smooth information exchange and collaborative strategies.Thrive in a fast-paced environment that encourages innovation and rapid iteration.QualificationsPhD in Computational Chemistry, Structural Biology, or a related discipline. Candidates with a PhD in organic or medicinal chemistry and substantial laboratory experience transitioning into industry roles in CADD are also encouraged to apply.Extensive knowledge of structure-based drug design and protein-ligand interactions.Expertise in using industry-standard CADD tools, including MOE, PyMOL, and Schrodinger Suite.A minimum of 2 years of experience in the pharmaceutical or biotech industry as a CADD scientist, with practical involvement in active drug discovery projects.While onsite presence at our San Diego lab is preferred for collaboration, we are open to considering remote team members as well.What We OfferAttractive SalaryComprehensive Health Care Plans (Medical, Dental, and Vision fully covered for employees)An opportunity to work in a pioneering environment with the latest technologies in drug discovery.

Join AbbVie as a Senior Scientist II in Analytical Development, where your expertise will contribute to innovative solutions in biopharmaceuticals. You will collaborate with a dynamic team, leveraging your analytical skills to drive research and development efforts. This role is pivotal in advancing our mission to improve patient outcomes through groundbreaking therapies.

Genesis Molecular AI is on a mission to transform drug discovery through innovative computational chemistry solutions. We are building a premier team of experts in computational chemistry, and we invite you to join us as a Senior CADD Scientist. In this pivotal role, you will collaborate closely with our cutting-edge wet lab scientists and work alongside our distributed computational chemistry and CADD science teams throughout the United States.Key Responsibilities:Employ a blend of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a varied target landscape, including innovative targets with limited chemical precedents.Implement methodologies such as virtual screening, molecular simulation, and potency and ADMET prediction to facilitate critical decision-making processes in drug discovery.Work collaboratively with medicinal chemists to design molecules and develop tailored computational strategies for specific projects.Serve as a bridge among teams, effectively communicating between our computational chemistry and medicinal chemistry groups to promote seamless information exchange and collaborative decision-making.Thrive in a dynamic environment that encourages innovation and rapid iteration.

Join Oura Health as a Senior Algorithm Scientist and play a pivotal role in advancing our innovative health technology. In this position, you will leverage your expertise in algorithm development to enhance our cutting-edge solutions that empower users to optimize their health and wellness. Collaborate with a dynamic team of engineers and scientists to design, implement, and validate algorithms that will shape the future of personal health tracking.

At Genesis Molecular AI, we are on a mission to transform the landscape of drug discovery by forming a premier computational chemistry team that leverages advanced machine learning techniques and biophysical simulations. We are actively looking for a Principal CADD Scientist to collaborate with our scientists in our cutting-edge wet lab and coordinate with our remote computational chemistry and CADD science teams throughout the United States.Key ResponsibilitiesEmploy both established and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a diverse range of targets, including innovative targets with minimal chemical precedents.Implement strategies such as virtual screening, molecular simulations, and predictive analytics for potency and ADMET to inform critical decision-making in drug development.Work collaboratively with medicinal chemists on molecular design and the formulation of project-specific computational methodologies.Serve as a liaison among teams, ensuring effective communication between computational chemistry and medicinal chemistry groups to facilitate seamless information exchange and collaborative decision-making.Thrive in a dynamic environment that fosters innovation and rapid iteration.QualificationsPhD in Computational Chemistry, Structural Biology, or a related discipline. This role is also suitable for PhD-level professionals in organic or medicinal chemistry with substantial lab experience who have transitioned into CADD roles.In-depth knowledge of structure-based drug design and protein-ligand interactions.Expertise in using industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite.A minimum of 5 years of relevant industry experience as a CADD scientist in pharmaceuticals or biotechnology, with direct involvement in active drug discovery projects.While onsite presence in our San Diego lab is preferred for collaboration, we welcome applicants interested in remote opportunities.What We OfferCompetitive salary and benefits packageComprehensive health care plans (including medical, dental, and vision, fully covered for employees)Eligibility for stock options

About Veracyte Veracyte, Inc. is dedicated to transforming cancer care and improving patient outcomes around the world. The team works in a mission-driven environment, supporting clinicians with innovative solutions and quality insights that help guide life-changing decisions. Employees are encouraged to make a real impact and grow in a collaborative setting known as the Veracyte way. Core Values We Seek A Better Way: Innovating boldly, learning from challenges, and showing resilience to enhance cancer care. We Make It Happen: Acting with urgency, aiming for excellence, and bringing joy to hard work. We Are Stronger Together: Collaborating openly, seeking understanding, and celebrating shared achievements. We Care Deeply: Valuing differences, maintaining integrity, and supporting each other. Role Overview The Senior Bioimage Scientist will join the Discovery Research team, focusing on tissue-based oncology diagnostics. This position connects pathologists, biologists, and AI/ML teams, contributing to the development of new assays, digital pathology AI tools, biological interpretation, and diagnostic product advancement. Both wet and dry lab work are part of the role, including developing, optimizing, and validating imaging assays and quantitative image analysis. The goal is to link biological and clinical questions with clear, interpretable image-derived metrics and features. Location San Diego, California (Hybrid)

AbbVie Inc. is looking for a Scientist I to join the Formulation and Process Development team in San Diego. The main focus of this position is to create and refine drug formulations that contribute to improved patient outcomes. Key responsibilities Design and execute laboratory experiments focused on drug formulation. Interpret experimental results and use findings to inform formulation strategies. Collaborate with team members from various scientific backgrounds to address development challenges. Assist in developing and optimizing manufacturing processes for new therapies. Location This position is based in San Diego.

Join AbbVie as a Principal Research Scientist II in our Analytical Development team, where you will play a pivotal role in advancing our therapeutic solutions. Your expertise will be crucial in developing and validating analytical methods, ensuring our products meet the highest standards of quality and efficacy.This position offers a unique opportunity to collaborate with cross-functional teams, driving innovation and excellence in our research initiatives. If you are passionate about scientific discovery and eager to contribute to impactful projects, we invite you to apply.

Capricor Therapeutics (NASDAQ: CAPR) is a pioneering biotechnology company focused on developing groundbreaking cell and exosome-based therapies for rare diseases. Our flagship product, Deramiocel (CAP-1002), is currently in late-stage development targeting Duchenne muscular dystrophy. Additionally, we are utilizing our innovative StealthX™ exosome platform to enhance targeted delivery systems and advance vaccinology initiatives. Each of our programs embodies our dedication to pushing scientific boundaries and providing transformative treatments for patients and their families.The Analytical Development Scientist plays a vital role as a senior technical contributor within our Analytical Development team. This position involves leading the development, optimization, and validation of sophisticated analytical methods that support our cell therapy and biologic products. Operating with a high level of independence and scientific acumen, the Scientist will oversee cross-functional projects, steer assay strategies, and ensure compliance with regulatory standards and program timelines. This role is crucial for making technical decisions, facilitating the progression of projects from initial development through to commercialization, and mentoring team members while fostering robust collaboration across departments.

AbbVie is hiring an Associate Scientist I/II for its Formulation & Process Development team in San Diego. This position plays a key part in advancing biopharmaceutical products from concept to practical use. Role overview The Associate Scientist works alongside experts from various disciplines to develop and refine drug formulations. The main goal is to create products that meet strict requirements for both efficacy and safety. Collaboration This role involves frequent interaction with colleagues from different scientific backgrounds, ensuring that each formulation benefits from a range of perspectives and expertise. Focus areas Supporting the formulation of new drug products Improving existing processes to enhance product quality Maintaining standards for safety and effectiveness throughout development

At Bee Genius, we are pioneering the future of work, today.This post was generated on behalf of our client:Job Description: We are seeking a highly accomplished and motivated Principal Scientist to become an integral part of our innovative team. In this role, you will spearhead groundbreaking scientific research and development initiatives, offer expert technical guidance, and catalyze innovation within our organization.Responsibilities:Lead and oversee scientific research projects from conception through to execution.Design and refine scientific methodologies and protocols for optimal outcomes.Conduct thorough analysis and interpretation of intricate data, effectively presenting insights to stakeholders.Mentor and provide technical support to junior scientists, fostering their professional growth.Collaborate with cross-functional teams to convert scientific discoveries into actionable applications.Remain abreast of the latest advancements and industry trends in your field.

Join Our Mission to Advance Global Health!Becton, Dickinson and Company (BD) is a leading global medical technology company dedicated to advancing the world of health. We strive to enhance medical discovery, diagnostics, and the delivery of care. With over 65,000 employees across the globe, we are committed to tackling some of the most pressing health challenges worldwide. As the Health Economics and Outcomes Research Lead, you will report to the Director of Scientific Affairs & Clinical Evidence within our Medical Affairs team. In this critical role, you will be tasked with developing and executing agile HEOR strategies in collaboration with both global and regional teams. Your expertise will drive impactful research and ultimately improve patient outcomes.

Millennium Health LLC is a highly regarded specialty laboratory with over a decade of expertise in medication monitoring and drug testing services. We empower healthcare professionals to effectively monitor both the use and misuse of prescription medications and illicit substances. Our testing solutions provide clinicians with objective insights into patients' recent drug usage, enhancing the effectiveness of treatment plans.We are seeking a Clinical Scientist who will take the lead in developing clinical LC-MS/MS assays. This role involves independently conducting original scientific research and creating innovative analytical technologies while managing project resources and timelines effectively.The responsibilities of this position include, but are not limited to: Acting as a technical leader to design, develop, and validate high-quality LC-MS/MS assays/products/technologies within established timelines. Providing formal and informal scientific mentoring to team members. Leveraging technical expertise to design experiments and independently contribute to multiple projects concurrently. Serving as a critical technical and scientific resource within the organization. Drafting, reviewing, and finalizing technical documentation essential for various stages of product development. Maintaining meticulous experimental records in compliance with company SOPs. Ensuring adherence to HIPAA, confidentiality, and compliance policies, procedures, and standards. Upholding administrative, physical, and technical cybersecurity controls. Consistent and reliable attendance is a must.

Join Experian's Innovation Lab as a Senior Data Scientist, where you will leverage your expertise to drive cutting-edge analytics and data-driven decision-making within our dynamic team. In this fully remote role, you will collaborate with cross-functional teams to develop innovative solutions that enhance business operations and customer experiences.

Millennium Health LLC is a distinguished accredited specialty laboratory, boasting over a decade of expertise in medication monitoring and drug testing services. We empower healthcare professionals with objective insights into patients' use of prescription medications and illicit drugs, ensuring effective monitoring of treatment plans.As a Computer Technician, you will play a vital role in delivering exceptional customer support for our business systems and technology. Your responsibilities encompass a wide array of devices, including desktops, laptops, mobile devices, and audio-visual equipment. You will also assist with cloud and on-premises business applications, manage new equipment configuration and deployment, and handle user and computer account creation during employee onboarding and offboarding processes. Our focus is on delivering a personalized level of service, leveraging Millennium Health’s advanced tools and solutions.Efficiently triage and prioritize client requests while documenting issues and actions taken.Offer technical support to end users via email, phone, and remote assistance.Resolve end-user requests for services, including installation, troubleshooting, and maintenance of desktop and laptop computers and peripherals.Build rapport with end users, providing tailored solutions while maintaining a high standard of service.Manage asset reception and update asset management records accordingly.Facilitate equipment movement within and between facilities.Stage equipment for building and imaging hardware setups and replacements.Be available for after-hours on-call rotation, including weekends.Adhere to HIPAA, confidentiality, and compliance policies and standards at all times.Ensure compliance with administrative, physical, and technical cybersecurity controls.Perform additional duties as assigned.

Positive Development seeks a Child Development Specialist in San Diego, CA to support children’s growth and learning. This position centers on building strong relationships with families and educators, working together to create environments where children can thrive both academically and emotionally. Role overview The Child Development Specialist will contribute expertise to shape and carry out programs tailored to each child’s needs. Collaboration is key: expect to partner with others to develop strategies that encourage healthy development and positive learning experiences. What you will do Work directly with children, families, and educators to support learning and emotional well-being Help design and implement individualized programs for child development Create supportive, inclusive environments that respond to each child’s strengths and challenges

Scismic is proud to partner with a leading global consulting firm renowned for its collaborative and inclusive culture that nurtures creativity, growth, and innovation. With a dedicated team of over 1,000 professionals operating across 50 international markets, this organization collaborates with prestigious clients to tackle intricate business challenges spanning various industries. The company embraces a 'builder’s mindset,' empowering employees to devise innovative solutions, create a lasting impact, and advance their careers in a supportive environment.We are currently seeking a talented Senior Data Scientist who possesses extensive expertise in Natural Language Processing and Large Language Models to join our consulting practice. You will collaborate directly with Fortune 500 clients, leveraging cutting-edge AI technologies to address complex business challenges across diverse sectors.

Job SummaryIambic Therapeutics is looking for an exceptional and driven Senior Associate Scientist to enhance our Chemistry team at our San Diego headquarters. This exciting position allows you to thrive in a vibrant, cross-disciplinary environment, where you will collaborate closely with medicinal chemists, biologists, DMPK scientists, computational chemists, machine learning experts, and software engineers. You will engage in every phase of the discovery process, from hit identification and lead optimization to candidate selection. This role is laboratory-focused and demands robust technical skills in organic synthesis, catalysis, and medicinal chemistry, alongside hands-on experience in the drug discovery process and a proven “drug hunter” mentality.Key ResponsibilitiesDesign, synthesize, purify, and characterize chemical compounds (10 mg–5 g scale) utilizing cutting-edge analytical techniques including LCMS, HPLC, and NMR, implementing both manual and automated parallel synthesis techniques.Identify and optimize reaction conditions through the use of screening kits and other efficient methodologies.Collaborate with the high-throughput experimentation team to guarantee successful execution of parallel chemistry experiments.Analyze biological and ADME-PK data using cheminformatics tools and contribute to data-driven discussions and strategic planning.Work alongside computational chemists to harness machine learning insights for the effective execution of the design–make–test cycle and platform development.Present findings to project teams and senior leadership, effectively communicating data, implications, and recommendations.QualificationsBS in Chemistry with 5+ years of experience in the pharmaceutical or biotechnology sector, or MS in Chemistry with 3+ years of relevant experience.Demonstrated expertise in multi-step organic synthesis, reaction optimization, Structure-Activity Relationship (SAR) analysis, and effective scientific presentation skills.Adeptness in a fast-paced, highly collaborative research atmosphere.Willingness to work onsite in San Diego.Preferred QualificationsExperience in high-throughput experimentation is advantageous.Familiarity with ADME-PK principles is a plus.5+ years of experience contributing to drug discovery projects is preferred.