Protein Purification Scientist

We are seeking a passionate and detail-oriented Protein Purification Scientist to join our dynamic team in San Diego. This role is critical to our mission of advancing biopharmaceutical development through innovative protein purification techniques.The ideal candidate will have experience in utilizing various purification methodologies and will be responsible for developing and optimizing protocols to ensure the highest quality of protein products. You will collaborate with cross-functional teams to support ongoing research projects.

JOB SUMMARYiambic therapeutics is on the lookout for a talented and motivated Analytical/Bioanalytical Scientist specializing in chromatography-based purification to enhance our drug discovery initiatives. The chosen candidate will be instrumental in facilitating high-throughput purification and assay workflows, supporting a weekly design-make-test-analysis cycle driven by our proprietary AI-based drug discovery engine. The ideal individual will possess extensive expertise in chromatographic purification, particularly in SFC and/or LC purification of small molecules, along with demonstrated skills in instrument troubleshooting, workflow optimization, and a solid understanding of ADME/DMPK assay design and execution.KEY RESPONSIBILITIESAct as the authority in chromatography-based purification, leveraging significant experience in SFC and LC purification of small molecules within a drug discovery context.Create, implement, and refine purification workflows, including preparative chromatography methods, fraction collection strategies, and post-purification data integration.Design and sustain automated purification workflows to enhance throughput, reproducibility, and sample quality.Work collaboratively with medicinal chemistry, purification, and DMPK teams to supply high-quality purified compounds, aiding in lead optimization and screening.Provide direct support, preventive maintenance, and troubleshooting for LC, LC/MS, and SFC instruments to reduce downtime and ensure continuous lab operations.Engage with vendors and automation partners for service, upgrades, installations, and workflow integration.Potentially assist with ADME/DMPK and physicochemical assays, contributing to method development, troubleshooting, and execution as required.Document purification workflows, maintenance activities, and troubleshooting in line with laboratory best practices.QUALIFICATIONSPossession of an advanced degree (M.S. or Ph.D.) in Analytical Chemistry, Chemistry, Chemical Engineering, or a related discipline; or equivalent industry experience.A minimum of a Ph.D. with 2 years of relevant experience OR an M.S. with 6 years of relevant experience.Extensive hands-on experience with chromatography-based purification, particularly SFC and/or LC purification of small molecules.Strong proficiency in operating, maintaining, and troubleshooting chromatography and mass spectrometry instruments.

Join our dynamic team at Integrated Resources Inc. as an Entry-Level Biochemist specializing in Protein Conjugation. This role is perfect for recent graduates eager to apply their knowledge in a real-world setting. You will be involved in the development and optimization of protein conjugation processes, contributing to innovative projects that impact health and biotechnology.As a key member of our research team, you will work under the guidance of experienced biochemists and gain hands-on experience with cutting-edge technologies. Your responsibilities will include conducting experiments, analyzing data, and collaborating with cross-functional teams to drive project success.

Role Overview Quantum-Si is seeking a Senior Marketing Manager focused on Protein Sequencing Solutions in San Diego, CA. This role leads marketing strategy and execution for the company’s protein sequencing offerings, working directly with scientists and researchers in biotechnology. What You Will Do Shape and implement marketing strategies for protein sequencing products Develop clear product positioning to reach key audiences Create and manage marketing campaigns tailored to researchers and scientists Work closely with cross-functional teams to strengthen Quantum-Si’s presence in the market

Job Overview: We are seeking a dedicated Bench Scientist II to join our dynamic team in San Diego. This role entails collaborating with fellow scientists to advance translational pharmacology research focusing on various clinical candidate compounds and late-stage assets. Key responsibilities include performing tissue culture, conducting cell-based assays, and executing western blot analysis. The ideal candidate will possess a solid background in cancer biology and relevant laboratory experience while demonstrating strong communication and teamwork skills.Key Responsibilities: Conduct tissue culture, cell-based assays, and western blot analysisWork with unscreened blood, human tissue, or human cell lines

At Bee Genius, we are pioneering the future of work, today.This post was generated on behalf of our client:Job Description: We are seeking a highly accomplished and motivated Principal Scientist to become an integral part of our innovative team. In this role, you will spearhead groundbreaking scientific research and development initiatives, offer expert technical guidance, and catalyze innovation within our organization.Responsibilities:Lead and oversee scientific research projects from conception through to execution.Design and refine scientific methodologies and protocols for optimal outcomes.Conduct thorough analysis and interpretation of intricate data, effectively presenting insights to stakeholders.Mentor and provide technical support to junior scientists, fostering their professional growth.Collaborate with cross-functional teams to convert scientific discoveries into actionable applications.Remain abreast of the latest advancements and industry trends in your field.

AbbVie is seeking a highly skilled Principal Research Scientist II specializing in Lipid Chemistry to join our innovative team in San Diego. This role is pivotal in advancing our research efforts and driving the development of novel lipid-based therapies. The ideal candidate will possess a robust background in lipid biochemistry, with a proven track record of impactful research and development.

Join Veracyte as a Senior Computational Development Scientist, where you will play a pivotal role in our mission to transform patient care through innovative genomics. In this remote position, you will leverage cutting-edge computational techniques to analyze complex genomic data, contributing to groundbreaking discoveries in cancer diagnostics.

Join Veracyte, a trailblazer in transforming cancer care on a global scale. Our team is dedicated to making a profound impact on patient lives while fostering an environment of continuous learning and growth. We embody the Veracyte way, a collaborative spirit driven by our core values to equip clinicians with the critical insights necessary for impactful patient decisions.Our Core Values:We Seek A Better Way: Innovating with courage, learning from challenges, and resiliently pursuing advancements in cancer care.We Make It Happen: Acting with urgency and dedication to quality while finding joy in our endeavors.We Are Stronger Together: Fostering open collaboration, understanding, and celebrating our collective successes.We Care Deeply: Valuing our differences, committing to integrity, and supporting one another. The Role:We are in search of a skilled Bioinformatics Scientist to enhance our Sustaining and Continuous Improvement team within Global Operations. This pivotal role involves constructing, refining, and supervising comprehensive quality control (QC) processes for RNA-based microarray and NGS high-volume Laboratory Developed Test (LDT) diagnostic products in CLIA labs. The Bioinformatics Scientist will ensure operational excellence, drive process enhancements, and collaborate with cross-functional teams for effective troubleshooting. The selected candidate will maintain product consistency through routine CLIA updates, contribute to verification and validation documentation, and engage in design reviews. This role promises valuable exposure to diagnostic product development and sustainability, with a direct impact on improving patient outcomes.

Genesis Molecular AI is on a mission to transform drug discovery through innovative computational chemistry solutions. We are building a premier team of experts in computational chemistry, and we invite you to join us as a Senior CADD Scientist. In this pivotal role, you will collaborate closely with our cutting-edge wet lab scientists and work alongside our distributed computational chemistry and CADD science teams throughout the United States.Key Responsibilities:Employ a blend of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a varied target landscape, including innovative targets with limited chemical precedents.Implement methodologies such as virtual screening, molecular simulation, and potency and ADMET prediction to facilitate critical decision-making processes in drug discovery.Work collaboratively with medicinal chemists to design molecules and develop tailored computational strategies for specific projects.Serve as a bridge among teams, effectively communicating between our computational chemistry and medicinal chemistry groups to promote seamless information exchange and collaborative decision-making.Thrive in a dynamic environment that encourages innovation and rapid iteration.

Join our dynamic team as a Scientist II, where you will leverage your expertise to drive innovation and contribute to cutting-edge research projects. You will work collaboratively with a team of professionals in a stimulating environment that fosters growth and creativity.

Join our innovative team at Artech Information Systems LLC as a Research Scientist. We are seeking a dedicated individual to contribute to groundbreaking research initiatives. You will engage in scientific inquiry, data analysis, and collaborative projects that push the boundaries of knowledge in your field.

At Art of Problem Solving (AoPS), data is at the heart of our mission to engage and retain families across the globe. With a reach extending to tens of thousands of students, our marketing strategies encompass various channels, including acquisition, campaign performance, lifecycle engagement, brand awareness, and community growth. The insights we gain from these initiatives are only as valuable as the decisions they inform.We are seeking a skilled Data Scientist to join our Marketing and Growth teams as a vital analytical partner. This role is designed for a full-stack individual contributor adept at conducting in-depth analyses, creating customer segments, measuring attribution, designing experiments, and addressing complex, high-impact marketing questions. Your contributions will enhance our marketing and growth strategies, bridging the gap between analytics and strategic decision-making.In collaboration with our marketing and growth teams, you will help shape our marketing strategies, assess channel performance, and ensure we effectively reach and convert audiences with compelling messages that drive enrollment.

Join LanceSoft, Inc. as a Research Scientist I in the vibrant city of San Diego, California. In this entry-level role, you will play a crucial part in supporting scientific research initiatives, collaborating with senior scientists, and contributing to innovative projects within our dynamic team.

Join our dynamic team at Integrated Resources, Inc. as a Research Scientist I. In this role, you will contribute to cutting-edge research initiatives, collaborating with multidisciplinary teams to innovate and develop groundbreaking solutions.

About Veracyte Veracyte, Inc. is dedicated to transforming cancer care and improving patient outcomes around the world. The team works in a mission-driven environment, supporting clinicians with innovative solutions and quality insights that help guide life-changing decisions. Employees are encouraged to make a real impact and grow in a collaborative setting known as the Veracyte way. Core Values We Seek A Better Way: Innovating boldly, learning from challenges, and showing resilience to enhance cancer care. We Make It Happen: Acting with urgency, aiming for excellence, and bringing joy to hard work. We Are Stronger Together: Collaborating openly, seeking understanding, and celebrating shared achievements. We Care Deeply: Valuing differences, maintaining integrity, and supporting each other. Role Overview The Senior Bioimage Scientist will join the Discovery Research team, focusing on tissue-based oncology diagnostics. This position connects pathologists, biologists, and AI/ML teams, contributing to the development of new assays, digital pathology AI tools, biological interpretation, and diagnostic product advancement. Both wet and dry lab work are part of the role, including developing, optimizing, and validating imaging assays and quantitative image analysis. The goal is to link biological and clinical questions with clear, interpretable image-derived metrics and features. Location San Diego, California (Hybrid)

Join Veracyte, a leader in transforming cancer care through innovative diagnostics that empower patients and clinicians alike. At Veracyte, we provide an inspiring work environment where you can make a significant impact on patients' lives while advancing your career. Our culture, known as the Veracyte way, emphasizes collaboration, resilience, and a commitment to excellence.Our Core Values:We Seek A Better Way: We boldly innovate and learn from challenges to improve cancer care.We Make It Happen: We prioritize urgency, quality, and enjoyment in our work.We Are Stronger Together: We foster open collaboration and celebrate our collective successes.We Care Deeply: We honor our diverse backgrounds and support each other in doing what is right.The Role:We are on the lookout for an enthusiastic Bioinformatics Research Scientist to join our Translational Bioinformatics group within the Bioinformatics and Data Science Team. This pivotal role involves leveraging computational and statistical techniques on extensive transcriptomic and genomic datasets, particularly focusing on prostate cancer biology and its clinical implications. The ideal candidate will play a key role in identifying clinically relevant molecular signatures that enhance disease stratification, prognosis, and the development of diagnostics, while effectively communicating findings to both scientific and clinical audiences. This position offers a unique opportunity to bridge the realms of data science, biology, and clinical research through close collaboration with scientists, clinicians, and cross-functional teams to convert complex data into actionable insights.

Capricor Therapeutics (NASDAQ: CAPR) is a pioneering biotechnology firm committed to developing cutting-edge cell and exosome-based therapies for rare diseases. Our flagship innovation, Deramiocel (CAP-1002), is currently in late-stage development targeting Duchenne muscular dystrophy. Additionally, we leverage our proprietary StealthX™ exosome platform to explore new avenues in targeted delivery and vaccinology. Each initiative exemplifies our dedication to advancing scientific boundaries and providing transformative treatments to patients and families in need.We are looking for a Scientist to join our Pre-Clinical team, where you will play a crucial role in advancing our therapeutic programs. Your responsibilities will include designing, executing, and optimizing in vivo research activities and preclinical studies. This position demands extensive expertise in in vivo methodologies, exceptional technical skills, and the capability to conduct intricate operations within a regulated environment.

At Genesis Molecular AI, we are on a mission to transform the landscape of drug discovery by forming a premier computational chemistry team that leverages advanced machine learning techniques and biophysical simulations. We are actively looking for a Principal CADD Scientist to collaborate with our scientists in our cutting-edge wet lab and coordinate with our remote computational chemistry and CADD science teams throughout the United States.Key ResponsibilitiesEmploy both established and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a diverse range of targets, including innovative targets with minimal chemical precedents.Implement strategies such as virtual screening, molecular simulations, and predictive analytics for potency and ADMET to inform critical decision-making in drug development.Work collaboratively with medicinal chemists on molecular design and the formulation of project-specific computational methodologies.Serve as a liaison among teams, ensuring effective communication between computational chemistry and medicinal chemistry groups to facilitate seamless information exchange and collaborative decision-making.Thrive in a dynamic environment that fosters innovation and rapid iteration.QualificationsPhD in Computational Chemistry, Structural Biology, or a related discipline. This role is also suitable for PhD-level professionals in organic or medicinal chemistry with substantial lab experience who have transitioned into CADD roles.In-depth knowledge of structure-based drug design and protein-ligand interactions.Expertise in using industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite.A minimum of 5 years of relevant industry experience as a CADD scientist in pharmaceuticals or biotechnology, with direct involvement in active drug discovery projects.While onsite presence in our San Diego lab is preferred for collaboration, we welcome applicants interested in remote opportunities.What We OfferCompetitive salary and benefits packageComprehensive health care plans (including medical, dental, and vision, fully covered for employees)Eligibility for stock options

Join Integrated Resources, Inc. as an Associate Immunoassay Scientist in the vibrant city of San Diego! In this role, you will have the opportunity to work with a dynamic team and engage in innovative research and development in the field of immunoassays. Your contributions will be crucial in advancing our scientific capabilities and enhancing our product offerings.