Principal Research Scientist II - Analytical Development

Join AbbVie as a Principal Research Scientist II in our Analytical Development team, where you will play a pivotal role in advancing our therapeutic solutions. Your expertise will be crucial in developing and validating analytical methods, ensuring our products meet the highest standards of quality and efficacy.This position offers a unique opportunity to collaborate with cross-functional teams, driving innovation and excellence in our research initiatives. If you are passionate about scientific discovery and eager to contribute to impactful projects, we invite you to apply.

AbbVie is seeking a highly skilled Principal Research Scientist II specializing in Lipid Chemistry to join our innovative team in San Diego. This role is pivotal in advancing our research efforts and driving the development of novel lipid-based therapies. The ideal candidate will possess a robust background in lipid biochemistry, with a proven track record of impactful research and development.

JOB SUMMARYiambic therapeutics is on the lookout for a talented and motivated Analytical/Bioanalytical Scientist specializing in chromatography-based purification to enhance our drug discovery initiatives. The chosen candidate will be instrumental in facilitating high-throughput purification and assay workflows, supporting a weekly design-make-test-analysis cycle driven by our proprietary AI-based drug discovery engine. The ideal individual will possess extensive expertise in chromatographic purification, particularly in SFC and/or LC purification of small molecules, along with demonstrated skills in instrument troubleshooting, workflow optimization, and a solid understanding of ADME/DMPK assay design and execution.KEY RESPONSIBILITIESAct as the authority in chromatography-based purification, leveraging significant experience in SFC and LC purification of small molecules within a drug discovery context.Create, implement, and refine purification workflows, including preparative chromatography methods, fraction collection strategies, and post-purification data integration.Design and sustain automated purification workflows to enhance throughput, reproducibility, and sample quality.Work collaboratively with medicinal chemistry, purification, and DMPK teams to supply high-quality purified compounds, aiding in lead optimization and screening.Provide direct support, preventive maintenance, and troubleshooting for LC, LC/MS, and SFC instruments to reduce downtime and ensure continuous lab operations.Engage with vendors and automation partners for service, upgrades, installations, and workflow integration.Potentially assist with ADME/DMPK and physicochemical assays, contributing to method development, troubleshooting, and execution as required.Document purification workflows, maintenance activities, and troubleshooting in line with laboratory best practices.QUALIFICATIONSPossession of an advanced degree (M.S. or Ph.D.) in Analytical Chemistry, Chemistry, Chemical Engineering, or a related discipline; or equivalent industry experience.A minimum of a Ph.D. with 2 years of relevant experience OR an M.S. with 6 years of relevant experience.Extensive hands-on experience with chromatography-based purification, particularly SFC and/or LC purification of small molecules.Strong proficiency in operating, maintaining, and troubleshooting chromatography and mass spectrometry instruments.

At Bee Genius, we are pioneering the future of work, today.This post was generated on behalf of our client:Job Description: We are seeking a highly accomplished and motivated Principal Scientist to become an integral part of our innovative team. In this role, you will spearhead groundbreaking scientific research and development initiatives, offer expert technical guidance, and catalyze innovation within our organization.Responsibilities:Lead and oversee scientific research projects from conception through to execution.Design and refine scientific methodologies and protocols for optimal outcomes.Conduct thorough analysis and interpretation of intricate data, effectively presenting insights to stakeholders.Mentor and provide technical support to junior scientists, fostering their professional growth.Collaborate with cross-functional teams to convert scientific discoveries into actionable applications.Remain abreast of the latest advancements and industry trends in your field.

Join AbbVie as a Senior Scientist II in Analytical Development, where your expertise will contribute to innovative solutions in biopharmaceuticals. You will collaborate with a dynamic team, leveraging your analytical skills to drive research and development efforts. This role is pivotal in advancing our mission to improve patient outcomes through groundbreaking therapies.

Join Veracyte, a leader in transforming cancer care through innovative diagnostics that empower patients and clinicians alike. At Veracyte, we provide an inspiring work environment where you can make a significant impact on patients' lives while advancing your career. Our culture, known as the Veracyte way, emphasizes collaboration, resilience, and a commitment to excellence.Our Core Values:We Seek A Better Way: We boldly innovate and learn from challenges to improve cancer care.We Make It Happen: We prioritize urgency, quality, and enjoyment in our work.We Are Stronger Together: We foster open collaboration and celebrate our collective successes.We Care Deeply: We honor our diverse backgrounds and support each other in doing what is right.The Role:We are on the lookout for an enthusiastic Bioinformatics Research Scientist to join our Translational Bioinformatics group within the Bioinformatics and Data Science Team. This pivotal role involves leveraging computational and statistical techniques on extensive transcriptomic and genomic datasets, particularly focusing on prostate cancer biology and its clinical implications. The ideal candidate will play a key role in identifying clinically relevant molecular signatures that enhance disease stratification, prognosis, and the development of diagnostics, while effectively communicating findings to both scientific and clinical audiences. This position offers a unique opportunity to bridge the realms of data science, biology, and clinical research through close collaboration with scientists, clinicians, and cross-functional teams to convert complex data into actionable insights.

Capricor Therapeutics (NASDAQ: CAPR) is a pioneering biotechnology company focused on developing groundbreaking cell and exosome-based therapies for rare diseases. Our flagship product, Deramiocel (CAP-1002), is currently in late-stage development targeting Duchenne muscular dystrophy. Additionally, we are utilizing our innovative StealthX™ exosome platform to enhance targeted delivery systems and advance vaccinology initiatives. Each of our programs embodies our dedication to pushing scientific boundaries and providing transformative treatments for patients and their families.The Analytical Development Scientist plays a vital role as a senior technical contributor within our Analytical Development team. This position involves leading the development, optimization, and validation of sophisticated analytical methods that support our cell therapy and biologic products. Operating with a high level of independence and scientific acumen, the Scientist will oversee cross-functional projects, steer assay strategies, and ensure compliance with regulatory standards and program timelines. This role is crucial for making technical decisions, facilitating the progression of projects from initial development through to commercialization, and mentoring team members while fostering robust collaboration across departments.

Join our dynamic team as a Scientist II, where you will leverage your expertise to drive innovation and contribute to cutting-edge research projects. You will work collaboratively with a team of professionals in a stimulating environment that fosters growth and creativity.

Join AbbVie as a Scientist II specializing in In Vitro Pharmacology. In this pivotal role, you will collaborate with a dynamic team of scientists to drive innovative research that advances our understanding of pharmacological compounds. Your expertise will contribute to the development of groundbreaking therapies aimed at improving patient outcomes.

Job Overview: We are seeking a dedicated Bench Scientist II to join our dynamic team in San Diego. This role entails collaborating with fellow scientists to advance translational pharmacology research focusing on various clinical candidate compounds and late-stage assets. Key responsibilities include performing tissue culture, conducting cell-based assays, and executing western blot analysis. The ideal candidate will possess a solid background in cancer biology and relevant laboratory experience while demonstrating strong communication and teamwork skills.Key Responsibilities: Conduct tissue culture, cell-based assays, and western blot analysisWork with unscreened blood, human tissue, or human cell lines

Join our innovative team at Artech Information Systems LLC as a Research Scientist. We are seeking a dedicated individual to contribute to groundbreaking research initiatives. You will engage in scientific inquiry, data analysis, and collaborative projects that push the boundaries of knowledge in your field.

We are on the lookout for exceptional scientists to join our Discovery Machine Learning team at Iambic Therapeutics. This position will play a pivotal role in utilizing cutting-edge machine learning techniques to enhance our drug discovery initiatives. You will collaborate with drug discovery teams focused on developing innovative therapeutics for a variety of conditions. Your work will center around our leading machine learning models, such as Enchant, our multimodal transformer model designed for predicting drug-target interactions and molecular properties. This opportunity is based at our headquarters in San Diego.

Join LanceSoft, Inc. as a Research Scientist I in the vibrant city of San Diego, California. In this entry-level role, you will play a crucial part in supporting scientific research initiatives, collaborating with senior scientists, and contributing to innovative projects within our dynamic team.

Join our dynamic team at Integrated Resources, Inc. as a Research Scientist I. In this role, you will contribute to cutting-edge research initiatives, collaborating with multidisciplinary teams to innovate and develop groundbreaking solutions.

Role Overview iambic therapeutics is seeking a Principal Scientist in Medicinal Chemistry to join the team onsite at our San Diego headquarters. This role calls for an accomplished medicinal chemist who brings a strong track record in drug discovery and thrives in a collaborative, multidisciplinary setting. The position involves close interaction with teams focused on automated experimentation, AI-driven molecular design, property prediction, and bioassay data generation. What You Will Do Design and refine strategies to identify and optimize lead molecules for potency, selectivity, and ADME properties, using multivariate SAR analysis and hypothesis-driven design. Apply a broad range of modern organic chemistry transformations and synthetic methodologies, including parallel experimentation, to advance project goals. Work closely with colleagues in molecular and cellular biology, pharmacology, computational chemistry, ADME, and related groups to drive discovery efforts. Shape the use of computational approaches, automated synthesis, and high-throughput experimentation in medicinal chemistry projects. Collaborate with AI and machine learning teams to build and apply predictive models for novel molecule design. Clearly communicate project updates and findings to the broader team and stakeholders. Contribute to the Chemistry research group, supporting a culture of scientific rigor, innovation, and teamwork. Qualifications BS, MS, or PhD in chemistry, with a focus on synthetic organic chemistry. Direct experience in small molecule drug discovery within biotech or pharma: minimum 15+ years with a BS, 12+ years with an MS, or 8+ years with a PhD. Documented success advancing drug discovery programs from lead identification through advanced candidate stages. Deep experience optimizing lead compounds for potency, selectivity, ADME, and pharmacokinetics. Expert knowledge of modern synthetic organic chemistry methods, supported by publications and patents. Hands-on familiarity with target protein degradation and modalities such as molecular glues and PROTACs. This position is based onsite at our San Diego HQ.

About Capricor Therapeutics Capricor Therapeutics (NASDAQ: CAPR) is a biotechnology company focused on developing cell and exosome-based therapies for rare diseases. The company’s lead product, Deramiocel (CAP-1002), is in late-stage development for Duchenne muscular dystrophy. Capricor’s StealthX™ exosome platform supports new approaches in targeted delivery systems and vaccinology, with a mission to advance science and deliver new treatments for patients and families facing serious conditions. Role Overview: Quality Control Scientist, Analytical Controls This role is based in San Diego (SD1). The Quality Control Scientist, Analytical Controls, develops, qualifies, and manages analytical control materials for QC assays. The scientist will generate and maintain both positive and negative controls, design and execute analytical studies, and troubleshoot or improve analytical methods used in QC testing. Key Responsibilities Develop and qualify analytical control materials for use in QC assays. Manage the lifecycle of control materials, including ongoing maintenance and documentation. Design and conduct analytical studies to support QC operations. Troubleshoot and refine analytical methodologies as needed for QC testing. Ensure reliability, reproducibility, and regulatory compliance of QC assays. Provide scientific guidance on assay control strategies. Collaborate with teams in Quality Control, Analytical Development, Process Development, Manufacturing, and Quality to support analytical readiness for Capricor’s therapeutic programs. Collaboration This position works closely with multiple teams to ensure analytical controls meet the needs of Capricor’s research and manufacturing efforts. The scientist will contribute expertise to cross-functional projects and help maintain high standards for QC laboratory performance.

AbbVie is hiring an Associate Scientist I/II for its Formulation & Process Development team in San Diego. This position plays a key part in advancing biopharmaceutical products from concept to practical use. Role overview The Associate Scientist works alongside experts from various disciplines to develop and refine drug formulations. The main goal is to create products that meet strict requirements for both efficacy and safety. Collaboration This role involves frequent interaction with colleagues from different scientific backgrounds, ensuring that each formulation benefits from a range of perspectives and expertise. Focus areas Supporting the formulation of new drug products Improving existing processes to enhance product quality Maintaining standards for safety and effectiveness throughout development

We are seeking a dedicated and detail-oriented Research Associate II to join our dynamic team in San Diego. In this role, you will be responsible for conducting research, analyzing data, and contributing to the development of innovative solutions. You will work collaboratively with senior researchers and other team members to support ongoing projects and initiatives.

Join the Institutional Animal Care and Use Program team as an IACUC Research Specialist II at The Scripps Research Institute (TSRI). This key role is pivotal in upholding TSRI's commitment to compliance with federal regulations governing animal research and educational activities. You will provide essential support and guidance to the Institutional Animal Care and Use Committee (IACUC) on a daily basis, ensuring the institution adheres to the highest standards of animal care and use. As a recognized expert in regulatory requirements, you will advise on compliance matters related to TSRI's animal care program.RESPONSIBILITIES AND DUTIES* Conduct thorough reviews of incoming research protocols and amendments, checking for grant/protocol alignment as well as verifying consistency with previously submitted versions;* Draft comprehensive memos detailing review findings, including suggestions for improvements;* Organize and participate in IACUC meetings, setting the agenda, documenting minutes, and managing post-meeting communications with investigators;* Maintain document control and track the research animal protocol review process daily, including oversight of the IACUC email, document processing, and data entry across various systems;* Provide guidance to TSRI faculty, staff, and students involved in animal-related research to ensure compliance with federal and institutional guidelines;* Track veterinary observations, protocol non-compliance, and regulatory exceptions;* Aid in the development and execution of a continuing review program for monitoring IACUC protocols and animal-related activities, including delivering remedial education and training to research personnel as necessary;* Perform comparative protocol reviews against grants and lab practices;* Schedule and prepare for semi-annual inspections of research facilities; compile and submit reports approved by the IACUC to the Institutional Official;* Serve as a liaison between animal husbandry/veterinary staff and IACUC regarding compliance issues;* Assist in creating and delivering training programs for faculty, staff, and students;* Maintain the IACUC web page;* Support the writing and submission of Standard Operating Procedures and IACUC newsletters for review;* Undertake other responsibilities as assigned.

Join Veracyte, a trailblazer in transforming cancer care on a global scale. Our team is dedicated to making a profound impact on patient lives while fostering an environment of continuous learning and growth. We embody the Veracyte way, a collaborative spirit driven by our core values to equip clinicians with the critical insights necessary for impactful patient decisions.Our Core Values:We Seek A Better Way: Innovating with courage, learning from challenges, and resiliently pursuing advancements in cancer care.We Make It Happen: Acting with urgency and dedication to quality while finding joy in our endeavors.We Are Stronger Together: Fostering open collaboration, understanding, and celebrating our collective successes.We Care Deeply: Valuing our differences, committing to integrity, and supporting one another. The Role:We are in search of a skilled Bioinformatics Scientist to enhance our Sustaining and Continuous Improvement team within Global Operations. This pivotal role involves constructing, refining, and supervising comprehensive quality control (QC) processes for RNA-based microarray and NGS high-volume Laboratory Developed Test (LDT) diagnostic products in CLIA labs. The Bioinformatics Scientist will ensure operational excellence, drive process enhancements, and collaborate with cross-functional teams for effective troubleshooting. The selected candidate will maintain product consistency through routine CLIA updates, contribute to verification and validation documentation, and engage in design reviews. This role promises valuable exposure to diagnostic product development and sustainability, with a direct impact on improving patient outcomes.