Senior Director of Oncology Clinical Trial Operations

As a Senior Director of Oncology Clinical Trial Operations at Natera, you will lead and optimize our clinical trial operations in the oncology space, ensuring the successful execution of clinical studies from inception to completion. You'll collaborate with cross-functional teams to develop innovative strategies that align with our mission to improve patient outcomes through precision medicine.Your leadership will be pivotal in managing a team of dedicated professionals, fostering a culture of excellence and continuous improvement. The ideal candidate will possess a deep understanding of oncology clinical trials, regulatory requirements, and an ability to navigate complex project landscapes.

Join Natera as a Senior Clinical Scientist in Oncology, where you will play a vital role in advancing our mission to transform the field of oncology through innovative diagnostics. You will leverage your expertise to drive clinical research projects and collaborate with cross-functional teams to support the development of cutting-edge solutions.

Join Our Mission to Safeguard Humanity!Vaxcyte is at the forefront of clinical-stage vaccine innovation, dedicated to developing high-fidelity vaccines aimed at protecting humanity from the serious and costly implications of bacterial diseases. Our commitment to eradicating or treating infections such as invasive pneumococcal disease, Group A Strep, and Shigella exemplifies our mission. With a clear and well-defined path to success, Vaxcyte is poised to make a significant impact. Our Approach: At Vaxcyte, what we do is as crucial as how we do it. Our collaboration is anchored in four enduring core values: *Rethink Convention: We infuse creativity and diverse thinking into every aspect of our work to continuously innovate how vaccines are delivered. *Aim High: We embrace our bold collective goal to courageously develop the most complex biologics ever attempted to safeguard humanity. *Lead with Heart: Every individual at Vaxcyte leads with a kindness-first, inclusive approach that fosters collaboration and vigorous debate to advance our business objectives. *Model Excellence: The scale of our challenge necessitates a shared commitment to integrity, accountability, equality, and transparency in communication and decision-making.Position Overview:The Associate Director of Quality Control Operations is a pivotal executive role within our global vaccine organization. This position is responsible for implementing Vaxcyte's analytical strategies at our Contract Development and Manufacturing Organizations (CDMOs) and Contract Research Organizations (CROs). Acting as the primary liaison for our CDMOs and CROs, you will ensure the delivery of high-quality, accurate, and compliant testing and analytical services. Collaborating closely with the analytical technical lead and various functions—including Analytics, Process Development, Manufacturing Science, Quality Assurance, and Regulatory Affairs—you will provide leadership and oversight for the execution of analytical strategies supporting analytical readiness and deliverables. You will be accountable for ensuring timely and compliant testing and release at our CDMO and CRO, facilitating a secure and uninterrupted supply of Vaxcyte’s groundbreaking therapies.

Be a Part of Our Mission to Safeguard Humanity!Vaxcyte is at the forefront of vaccine innovation, focusing on the development of high-fidelity vaccines aimed at protecting society from severe bacterial diseases that can lead to significant health challenges. Our commitment to combating bacterial infections, including invasive pneumococcal disease, Group A Streptococcus, and Shigella, positions us as leaders in the field. With a clear and defined path toward success, Vaxcyte is committed to making a lasting impact on global health. Our Approach: Values that Drive Us We believe that our mission is as important as our methodology. Our work is guided by four foundational values: *RETHINK CONVENTION: We embrace creativity and diverse perspectives to continuously innovate the delivery of vaccines. *AIM HIGH: Our ambitious goal is to develop the most complex biologics designed to protect humanity. *LEAD WITH HEART: Collaboration at Vaxcyte is rooted in kindness and inclusivity, fostering an environment where vigorous debate leads to meaningful outcomes. *MODEL EXCELLENCE: Meeting our challenges requires a collective commitment to integrity, accountability, and clarity in communication and decision-making.Position Summary:The Executive Director of Clinical Regulatory is a leadership role responsible for crafting and executing global regulatory strategies for clinical investigations and the commercialization of vaccines across both adult and pediatric populations. Working closely with Clinical Development and Safety teams, this position will provide regulatory oversight that supports the preparation of clinical development protocols, interpretation and summarization of clinical data, and the creation and management of clinical and pre-clinical regulatory documents. This role also entails liaising with regulatory authorities to secure commercial approval for innovative vaccine products.Candidates should possess extensive experience in developing and executing regulatory strategies for vaccines and preparing investigational and commercial regulatory submissions, such as IND/IMPD, BLA/MAA, and post-approval clinical and safety notifications. Strong communication skills are essential, particularly the ability to simplify complex regulatory issues and effectively convey potential options and opportunities.

Join Natera as a Lead Clinical Lab Scientist, where you will play a pivotal role in advancing our laboratory operations. We are seeking an experienced and passionate scientist who is ready to lead a team, drive innovation, and ensure the highest quality standards in our clinical laboratory environment.In this role, you will oversee laboratory procedures, mentor junior staff, and collaborate with cross-functional teams to optimize lab performance. Your expertise will be crucial in implementing new technologies and methodologies that enhance our testing capabilities and improve patient outcomes.

About Obvio AIEvery year, over 7,500 pedestrians lose their lives due to vehicular accidents in the U.S., a staggering increase of 70% over the last decade. Despite heightened awareness, numerous cities find it challenging to combat dangerous driving, resulting in inadequate 'Vision Zero' initiatives nationwide.At Obvio AI, we aim to revolutionize this landscape.We utilize solar-powered, AI-enhanced cameras to enforce traffic regulations in areas where pedestrians are most at risk—automating enforcement in ways that traditional systems and police departments cannot. Our innovative approach has already led to significant reductions in reckless driving and enhanced safety for pedestrians, drivers, and law enforcement.Founded by the creators of Motive’s AI dashcam, Obvio is supported by Bain Capital Ventures and Khosla Ventures. With a recent $22M Series A funding round, we are collaborating with some of the most progressive cities across the nation. Backed by meaningful revenue, a vast market, and strong policy support, we are building the intelligence layer for safer streets on a global scale.About the RoleAs the Head of Annotation Operations, you will oversee our annotation and review function from inception to execution as we expand our capabilities.This position will lead a team poised for substantial growth over the upcoming year. You will be responsible for designing and managing workflows, quality assurance systems, training programs, and performance evaluations essential for operating a high-throughput, safety- and compliance-critical operation.Your ResponsibilitiesAnnotation Operations & Workflow Management:Lead the implementation and ongoing enhancement of Obvio's annotation and review workflows for automated traffic enforcement.Translate enforcement requirements and edge cases into comprehensive review guidelines, task specifications, and escalation pathways.Ensure a balance between throughput, accuracy, and consistency in a high-pressure operational context.Organizational Scaling:Develop the operational framework for a rapidly growing review team, encompassing team structure, leadership roles, and quality assurance functions.Oversee recruitment, onboarding, and training programs to accelerate reviewer proficiency.Establish and manage performance assessment systems, including coaching, feedback, and accountability metrics.

Join Our Mission to Safeguard Humanity!At Vaxcyte, we are pioneering vaccine innovations aimed at developing high-fidelity vaccines to combat the dire consequences of bacterial diseases. These diseases pose significant health risks and financial burdens if not addressed. Our commitment extends to eradicating or treating various bacterial infections, including invasive pneumococcal disease, Group A Strep, and Shigella. We have a clear and strategic path to success, positioning Vaxcyte for long-term achievement. Our Approach: We believe that WHAT we do is equally important as HOW we do it! Our collaborative efforts are underpinned by four enduring core values: *RETHINK CONVENTION: We infuse creative and intellectual diversity into every aspect of our work to innovate and continuously improve the delivery of vaccines. *AIM HIGH: Together, we strive toward an ambitious goal of developing the most complex biologics to safeguard humanity. *LEAD WITH HEART: At Vaxcyte, we foster a kindness-first, inclusive approach to leadership, promoting collaboration and open debate that drives our business objectives forward. *MODEL EXCELLENCE: The scale of our challenges calls for a shared commitment to integrity, accountability, equality, and clarity in our communications and decision-making processes.Position Summary:The Senior Director of Global Logistics and Distribution will oversee the shipping and storage of all Vaxcyte CMC materials, including finished goods, bulk products, and samples. This role encompasses materials for Research, Development, Clinical, and Commercial purposes and will report directly to the Executive Director of Global Supply Chain.Key Responsibilities:Strategic Planning:Formulate and execute a global logistics and distribution strategy that aligns with corporate goals, including network design, transportation optimization, and warehousing operations.Operations Management:Guarantee the efficient, timely, compliant, and high-quality delivery of all materials within scope.Ensure robust pack-out designs with appropriate containers and components to maintain materials at target temperatures and facilitate efficient receipt.Establish strong shipping agreements with CMOs and suppliers to ensure seamless operations.

Role overview Natera seeks a Senior Manager of Research and Development to join the Oncology Product Development team in San Carlos, CA. This leader will oversee the development and optimization of next-generation sequencing (NGS)-based oncology diagnostic assays. The role also includes supporting product lifecycle management after launch. Success depends on technical leadership, strong collaboration across teams, and attention to product performance and scalability. What you will do Direct the technical development of NGS-based oncology assays, including project planning, execution, and coordination with multiple teams. Lead assay development from feasibility through verification and validation within a regulated CLIA environment. Work in partnership with Research, Informatics, Statistics, Software, Regulatory, Quality, and Commercial teams to bring products from concept to launch. Support post-launch activities such as process improvements, troubleshooting, and collaboration with Operations on commercialized assays. Prepare and review technical documents, including study protocols, reports, and validation materials to meet regulatory and product requirements. Mentor and manage team members, fostering their professional growth. Lead and oversee data analysis using statistical methods. Requirements PhD in Molecular Biology or a related field with at least 6 years of relevant industry experience, or BS/MS with a minimum of 8 years in biotech, including at least 2 years in management. Hands-on experience developing NGS-based assays in a regulated setting; CLIA experience preferred. Familiarity with CLIA laboratory workflows and implementing assays in production. Track record of leading projects and collaborating across functions; people management experience is a plus. Experience with high-throughput workflows or automation is beneficial. Knowledge and skills Strong technical background in oncology diagnostics and NGS technologies. Analytical thinking and problem-solving abilities. Proficiency in technical writing and documentation for regulated environments. Understanding of regulatory standards and design control processes, including LDT, CAP/CLIA, product development lifecycle, and change management. Excellent collaboration, communication, and interpersonal skills.

Become a Champion for Global Health!At Vaxcyte, we are at the forefront of vaccine innovation, developing cutting-edge vaccines designed to combat the severe and costly impacts of bacterial diseases. Our mission is to eliminate or effectively manage bacterial infections, including invasive pneumococcal disease, Group A Streptococcus, and Shigella. We have a clear trajectory towards success, and Vaxcyte is well-equipped to achieve our ambitious goals. Our Approach: What we do is equally as significant as how we accomplish it! Our collaborative efforts are driven by four core values: *RETHINK CONVENTION: We introduce creativity and diverse perspectives into every aspect of our work to innovate and continuously improve vaccine delivery methods. *AIM HIGH: We strive for excellence with a bold ambition to create some of the most intricate biologics ever developed to safeguard human health. *LEAD WITH HEART: Kindness and inclusivity are at the forefront of our leadership style, fostering collaboration and robust discussions that propel our business forward. *MODEL EXCELLENCE: We share an unwavering commitment to integrity, accountability, and clarity in all our communications and decisions.Position Overview:Vaxcyte is in search of a Senior Director, Product Launch Lead for VAX-31, who will spearhead the strategic planning and execution of our inaugural launch. This pivotal role involves coordinating cross-departmental initiatives from late-stage development through market introduction, ensuring readiness across supply chain, regulatory, medical affairs, and commercial operations. You will collaborate with senior leadership to outline launch strategies, manage timelines, address risks, and synchronize efforts among internal and external stakeholders to successfully introduce our products to the global market.

Vaxcyte, based in San Carlos, California, develops vaccines aimed at preventing serious bacterial diseases such as invasive pneumococcal disease, Group A Strep, and Shigella. The company’s mission is to advance vaccine science and help protect communities around the world. The team values fresh thinking, high standards, and open communication. Vaxcyte encourages new ideas to improve vaccine delivery, strives for significant progress in biologics, and emphasizes kindness, inclusivity, and clear communication. Integrity and accountability guide their approach to every challenge. Role overview The Senior Manager of Indirect Procurement for Clinical Development leads procurement efforts that support clinical development programs. This role serves as a strategic partner to Clinical Operations and works closely with Finance and Legal. Responsibilities span the entire procurement process for clinical trials, from project initiation through closeout, and require flexibility as indirect spend categories evolve. Key responsibilities Direct procurement support for clinical development initiatives Oversee the requisition to purchase order process for clinical trials Assist with vendor selection and coordinate contracts to ensure engagements are timely, compliant, and cost-effective Work with Clinical Operations, Finance, and Legal teams throughout the procurement lifecycle

Role Overview The Lead Clinical Laboratory Scientist at Natera, Inc. in San Carlos, CA, plays a key part in specimen analysis and daily lab operations. This position works closely with the supervisor to meet production goals and maintain high standards in laboratory practices. Main Responsibilities Verify specimen accuracy for patient testing and perform required laboratory tests with precision. Support daily laboratory operations by following standard operating procedures and minimizing errors. Maintain Good Laboratory Practices (GLP), reporting any deviations from protocols to management. Complete production tasks on schedule and process all case samples efficiently. Assist the supervisor with projects assigned by management. Serve as the main point of contact on the lab floor when the supervisor is absent. Train new team members in current laboratory procedures and help implement new processes. Support staff competency evaluations alongside the supervisor and laboratory trainer. Deliver specialized training on laboratory instruments and protocols. Troubleshoot and resolve equipment malfunctions and laboratory errors. Understand the full laboratory workflow and address operational issues as they arise. Ensure correct rollout of new laboratory procedures. Communicate laboratory issues and team concerns to supervisors or managers, offering solutions where possible. Report discrepancies in team performance to the supervisor. Provide constructive feedback during team performance evaluations. Participate in regular meetings with the supervisor. Promote professionalism and maintain team morale, serving as a role model for colleagues. Follow all departmental expectations. Handle Protected Health Information (PHI) in both paper and electronic formats, using various technologies as required. Complete all required HIPAA/PHI privacy, policy, and security training within the first 30 days of employment. Stay current with Natera training requirements. Perform other duties as assigned.

Location: San Carlos, CA (on-site) About 1X 1X builds versatile robots in San Carlos, California, with a focus on advancing AI and robotics for everyday life. The team aims to design humanoid robots that work alongside people, learning and adapting as they go. The goal: friendly, useful home robots that fit naturally into daily routines. Role Overview 1X seeks a Director of Maintenance and Repair Operations to build and lead the internal team responsible for keeping robotic systems running smoothly. This leader will shape the full workflow for diagnosing, repairing, and maintaining robots in a hands-on workshop environment. The work will span from early prototype support to scaling up for higher-volume production. The Director will play a key part in improving system reliability, gathering product feedback, and ensuring the company is ready for expanded operations. Success in this role calls for deep technical knowledge, strong operational judgment, and a willingness to work directly with the team in a startup setting. What You Will Do Build and lead the Maintenance and Repair organization for robotic systems. Refine and expand playbooks for diagnosing and troubleshooting complex electromechanical issues at both system and component levels. Create and scale repair workflows, including intake, triage, repair, validation, and return-to-service steps. Hire, coach, and develop a team of repair technicians and diagnostic/service engineers (including both exempt and non-exempt roles). Set clear roles, responsibilities, and career paths within the Maintenance and Repair team. Partner with Quality Assurance to build structured processes for failure tracking, root cause analysis, and ongoing improvement. Work closely with design, manufacturing, and reliability engineering teams to drive product improvements based on real-world and production feedback. Interpret and enforce the use of technical documentation such as schematics, work instructions, and bills of materials (BOMs). Maintain high standards for quality, safety, and traceability throughout operations. Support the shift from low-volume builds to higher-volume production as operations grow.

Shift: 3pm-11:30pmAbout 1XAt 1X, we innovate humanoid robots designed to work alongside humans, addressing labor shortages and fostering abundance in various sectors.The RoleIn this dynamic and impactful position, you will be responsible for operating humanoid robots in both research and development settings and, as technology progresses, in residential environments. As a Senior Operator, your role will involve executing tasks with meticulous precision, elevating team performance, contributing to process enhancements, and establishing benchmarks for operational excellence. You'll follow established procedures to gather high-quality data, assist in robot session support and annotation, monitor performance, address issues, and uphold safety and quality standards. Your contributions will directly influence the AI training process and shape how robots function in real-world scenarios.Key ResponsibilitiesUtilize humanoid robots with precision, adhering to standard operating procedures in lab and home environments.Demonstrate leadership by executing complex tasks consistently to ensure high-quality data collection.Employ a Virtual Reality headset for designated movements and actions as per project specifications.Facilitate robot sessions: prepare environments, assist in task execution, and interact with robots for seamless operation.Identify workflow inefficiencies and contribute to the enhancement of SOPs, tools, and processes.Annotate gathered data using internal tools to aid AI model training.Monitor robot performance and provide detailed issue logs with timestamps, video/screenshot evidence, and task context.Ensure all equipment is maintained in safe, operational condition, and elevate standards for operational readiness.Provide constructive feedback on equipment performance.Analyze and report on data collected during shifts.Communicate timely with leadership regarding any arising issues.As systems are deployed, deliver in-home support with professionalism and effective communication.Adhere to all safety protocols in lab and home environments.Maintain organized records of completed workflows and robot/system behaviors.Be prepared to work flexible shifts, including evenings, weekends, and overtime as necessary.

Shift: 7am-3:30pmAbout 1XAt 1X, we are pioneering the development of humanoid robots designed to collaborate with humans, addressing labor shortages and fostering abundance in various sectors.Role OverviewIn this dynamic and hands-on position, you will operate cutting-edge humanoid robots in both research and development environments, and as our technology advances, directly within customer homes. As a Senior Operator, you will uphold exceptional standards of precision and contribute to team performance enhancements, process optimizations, and operational excellence. Your responsibilities will include adhering to structured protocols for high-quality data collection, annotating and supporting robotic sessions, monitoring performance, reporting issues, and maintaining safety and quality standards. Your contributions are vital to the AI training process that influences real-world robot behavior.Key ResponsibilitiesOperate humanoid robots with precision according to standard operating procedures (SOPs) in laboratory and residential settings.Model best practices while executing complex tasks, ensuring consistent and high-quality data collection.Utilize virtual reality headsets to perform designated movements and actions as per project requirements.Support ongoing robot sessions by staging environments, assisting with task execution, and interacting with robots for seamless operation.Identify inefficiencies in workflows and proactively contribute to the enhancement of SOPs, tools, and processes.Annotate collected data using internal tools to support AI model training efforts.Monitor robot performance and document issues effectively, including timestamps, visual evidence, and task context.Ensure all equipment is maintained in a safe and operational state, elevating standards for readiness.Provide constructive feedback regarding equipment performance.Analyze and report data collected during your shift.Communicate promptly with leadership regarding any issues requiring attention.Deliver in-home support as systems are deployed, maintaining professionalism and clear communication.Adhere to all safety protocols in both lab and home environments.Keep thorough records of completed workflows and robot/system behaviors.Be flexible with shift work, including day/swing shifts, weekends, and additional hours as required.

Join Natera as a Lead Biostatistician in Clinical Research, where you will play a pivotal role in the design and analysis of clinical trials. You will collaborate closely with cross-functional teams and contribute to the advancement of innovative healthcare solutions. This is an exciting opportunity to lead statistical programming efforts, ensuring the highest standards of quality and compliance in clinical data analysis.

Join Natera as a Clinical Lab Supervisor, where you'll lead a team of professionals in a dynamic clinical laboratory environment. In this pivotal role, you will oversee daily laboratory operations, ensuring compliance with quality standards and regulatory requirements. Your leadership will foster a culture of excellence and innovation as you mentor and develop staff, driving continuous improvement in laboratory processes.

Join Natera as a Clinical Lab Supervisor, where you will lead and manage laboratory operations while ensuring compliance with standards and regulations. This pivotal role involves supervising laboratory staff, maintaining quality control, and collaborating with cross-functional teams to enhance lab efficiency.

About Q BioAt Q Bio, we are revolutionizing preventive healthcare. Collaborating with clinics and health systems, we launch cutting-edge longevity programs powered by the Q Exam—a proprietary evaluation that merges whole-body MRI with integrated biomarkers to furnish a clinically robust overview of health and early disease detection. Our mission extends beyond developing tools; we are crafting the data-driven future of personalized health.Your RoleWe are on the lookout for a Senior Technical Program Manager who will drive the successful delivery of Q Bio’s enterprise software and clinical technology initiatives. This pivotal role is responsible for overseeing complex, regulated programs, establishing a clear operational rhythm, identifying risks early, and ensuring disciplined follow-up across diverse teams. Working closely with Product, Engineering, Clinical, Quality, Security, and external stakeholders, the Senior Technical Program Manager will guarantee alignment and progress—infusing structure, visibility, and disciplined execution into multifaceted, cross-functional projects. In light of Q Bio’s evolving nature, this position will not only operate within current parameters but will also contribute to the development of systems, processes, and governance that facilitate predictable, scalable execution as the organization evolves.Key ResponsibilitiesAccountability & ProgressDefine clear ownership, milestones, and success criteria for all programs. Propel disciplined, visible progress and ensure that commitments are achieved or proactively escalated.Operational TransparencyCreate and maintain a comprehensive source of truth regarding program health, encompassing schedules, dependencies, risks, and resources. Offer leadership high-fidelity, decision-ready visibility.Interdependency ManagementProactively identify and manage cross-functional dependencies across Product, Engineering, Clinical, Regulatory, Security, and external collaborators to sustain program momentum.Engineering Force MultiplierOversee coordination, logistics, and follow-through to enhance execution efficiency, enabling engineers and scientists to concentrate on high-impact delivery and innovation.

Natera, Inc. is hiring a Clinical Lab Scientist I based in San Carlos, CA. This role plays a key part in supporting essential diagnostics by carrying out laboratory tests that directly inform patient care and clinical decisions. What you will do Perform laboratory tests following established protocols Help deliver accurate and timely diagnostic results Uphold quality standards throughout all testing procedures Role impact The work done in this position ensures that patients and clinicians have reliable information for making important healthcare decisions.

Join Natera as a Clinical Lab Scientist II, where you will play a pivotal role in our laboratory operations, contributing to groundbreaking genetic testing technologies. You will be responsible for performing complex laboratory tests, ensuring accuracy and compliance with all regulatory requirements. Your expertise will help us deliver critical insights and improve patient outcomes.