IT Systems Engineer at Orca Bio | Sacramento, CA

Join us at Orca Bio, where we are on a mission to transform the lives of individuals battling blood cancer. Every day, over a million people in the United States are facing this challenge, and while traditional allogeneic stem cell transplants have offered hope, they often come with significant risks, including fatal outcomes and severe complications such as graft vs. host disease. Our innovative biotechnology company is dedicated to redefining the transplant experience through advanced cell therapies that aim to improve survival rates while minimizing risks. We are committed to restoring health and vitality to our patients by providing them with purified, high-precision investigational cell therapies.Position Overview:As an IT Systems Engineer at Orca Bio, you will report to our IT Manager and play a vital role in designing, supporting, maintaining, and optimizing our IT infrastructure, both on-premise and in the cloud. Your expertise in systems and cloud platforms, combined with a proactive problem-solving attitude, will be essential for driving efficiency and reliability in our IT operations. You will have the opportunity to automate routine processes and implement scalable solutions that enhance our research and development environments. Strong communication and collaboration skills are a must, as you will work closely with cross-functional teams in a dynamic and fast-paced setting. A commitment to continuous learning and adaptability will be key to your success in this role.Location: This position is based on-site at our production facility in Sacramento, California.

Join the fight against blood cancer with Orca Bio, a pioneering late-stage biotechnology company that is revolutionizing the transplant process. Our mission is to enhance patient survival rates and minimize risks through cutting-edge cell therapies. With over one million individuals in the U.S. battling blood cancer, our innovative solutions aim to restore their lives by replacing compromised blood and immune systems with healthy alternatives.Our state-of-the-art, 100,000-square-foot manufacturing facility in Sacramento, CA, is integral to our success. This facility is dedicated to ensuring the reliable and consistent delivery of our high-precision cell therapy products, which are crucial for advancing our clinical pipeline and supporting the future commercial availability of life-saving treatments.The Production Planner plays a key role in orchestrating and scheduling production activities across our two production sites dedicated to clinical and commercial drug products. This dynamic position requires keen analytical skills to assess production specifications, capacity, and resources, ultimately developing production schedules that meet customer demands while optimizing efficiency.

At Orca Bio, we understand that over a million individuals in the United States are battling blood cancer. Traditional allogeneic stem cell transplants have provided hope, yet they often come with significant risks, including potential fatal outcomes and complications like graft versus host disease. Our late-stage biotechnology company is on a mission to transform the transplant landscape through innovative, next-generation cell therapies designed to enhance survival rates while minimizing risks. Our purified, high-precision investigational cell therapies aim not only to replace patients' blood and immune systems with healthy alternatives but also to restore their quality of life.As a Facility Coordinator, you will play a crucial role in ensuring the seamless operation and maintenance of our facility’s physical infrastructure. Your responsibilities will include coordinating maintenance tasks, overseeing calibration and certification activities, managing utility systems, liaising with service providers, and ensuring compliance with Good Manufacturing Practices (GMP) and safety regulations. You will collaborate closely with various departments to help achieve our organizational objectives.This is an on-site position located at 3400 Business Drive, Sacramento, CA, with a standard working schedule from Monday to Friday, 7 a.m. to 4 p.m. or 8 a.m. to 5 p.m.

Join Orca Bio, a pioneering late-stage biotechnology firm dedicated to transforming the transplant landscape. We are committed to advancing cell therapies that significantly improve survival rates while minimizing risks associated with traditional allogeneic stem cell transplants. Our state-of-the-art manufacturing facility, spanning 100,000 square feet in Sacramento, CA, plays a crucial role in ensuring the reliable delivery of our high-precision investigational cell therapies. The Engineer, Manufacturing Sciences & Technology (MSAT) will focus on enhancing the efficiency and safety of our drug product manufacturing processes. This position entails lifecycle management of commercial products, process monitoring, troubleshooting, implementing and validating process improvements, and supporting investigations as well as corrective and preventive actions.

Join Orca Bio, a pioneering late-stage biotechnology firm, in our mission to revolutionize the transplant process for blood cancer patients. Our innovative cell therapies aim to significantly enhance survival rates while minimizing risks associated with traditional allogeneic stem cell transplants. Our state-of-the-art 100,000-square-foot manufacturing facility in Sacramento, CA, is at the forefront of delivering high-precision cell therapy products that have the potential to transform lives.As the Manager of Manufacturing Sciences and Technology (MSAT), you will lead a team of process engineers across multiple shifts, ensuring the smooth operation of manufacturing processes to support both clinical and commercial production. Your responsibilities will encompass overseeing daily MSAT operations, addressing deviations, conducting product impact assessments, managing change controls, implementing CAPAs, performing risk assessments, facilitating tech transfers, and driving continuous improvement initiatives. Your leadership will be crucial in upholding product quality, operational efficiency, and compliance with regulatory standards.

Join us at Orca Bio, where we are dedicated to transforming the lives of patients battling blood cancer through innovative cell therapies. Our mission is to redefine the transplant process with our next-generation investigational therapies, aiming to enhance survival rates while minimizing risks. As a Material Handler on the Day Shift, you will play a vital role in ensuring the seamless handling, storage, and distribution of pharmaceutical materials essential for our cutting-edge cell therapy products, all while adhering to rigorous quality standards and regulatory guidelines.Core Responsibilities: You will manage warehouse materials and inventory operations, prepare kitting materials for production, and oversee the movement, intake, and shipping of drug products and samples to support our mission.

Over one million individuals in the United States are currently battling blood cancer. While the traditional allogeneic stem cell transplant has provided hope for many, it can also carry significant risks, including fatal outcomes and severe complications such as graft versus host disease. At Orca Bio, a cutting-edge biotechnology firm, we are revolutionizing the transplant process by creating next-generation cell therapies aimed at significantly enhancing survival rates while minimizing risks. Our goal is to not only replace patients' blood and immune systems with healthy alternatives but also to restore their quality of life. We have established a state-of-the-art 100,000-square-foot manufacturing facility in Sacramento, CA, to guarantee the consistent and reliable delivery of our high-precision cell therapy products. This facility is crucial for advancing our clinical pipeline and ensuring the future commercial availability of our life-saving therapies. The Director, Commercial Manufacturing will lead our cell therapy manufacturing operations and production support functions to ensure the reliable, compliant, and timely delivery of patient-specific therapies. This role is essential in driving consistent batch execution, operational discipline, and cross-functional collaboration to meet on-time patient delivery, all while upholding the highest quality and safety standards.The Director will develop and maintain robust production systems, implement lean manufacturing principles, and spearhead continuous improvement initiatives to scale operations in a dynamic, GMP-regulated environment.

About Nivagen Pharmaceuticals Nivagen Pharmaceuticals LLC develops and supplies affordable generic prescription and over-the-counter medications for the North American market. For more than a decade, the company has focused on quality, integrity, and respect, supporting its mission through vertical integration, advanced technology, and a commitment to high standards. Employees benefit from competitive pay, a strong benefits package, and ongoing training. Nivagen aims to improve healthcare access by providing reliable, cost-effective medicines. Role Overview: Sterile Manufacturing Associate The Sterile Manufacturing Associate works in Sacramento, CA and is responsible for aseptic and cleanroom manufacturing activities. This position requires strict adherence to cGMP standards, regulatory requirements, and internal standard operating procedures (SOPs). Careful attention to detail and the ability to follow established protocols help ensure the quality and safety of sterile drug products produced at Nivagen.

At Xometry (NASDAQ: XMTR), we are at the forefront of revolutionizing the manufacturing industry by connecting innovative thinkers with skilled manufacturers who can turn their visions into reality. Our digital marketplace empowers manufacturers with essential resources to expand their operations while simplifying the process for buyers from Fortune 1000 companies to access global manufacturing capabilities.We are currently in search of enthusiastic Mechanical Engineers to join our team as Manufacturing Solutions Engineers. In this pivotal role, you will be integrated within our key strategic accounts, serving as an extension of their engineering teams. This position requires a unique combination of customer interaction, technical knowledge, and operational execution. You will report to the Operations team while closely collaborating with Sales to drive growth and elevate customer satisfaction.This is an exceptional opportunity to be a part of a dynamic and expanding company leading the charge in digital manufacturing. If you are a driven Mechanical Engineer passionate about ensuring customer success and eager to make a significant impact, we invite you to apply!

Cranial Technologies is a pioneering organization solely devoted to the research and treatment of plagiocephaly, commonly referred to as flat head syndrome. With over 300,000 infants successfully treated, we are recognized as the foremost experts in this field and the leaders in pediatric cranial shaping orthoses.Additionally, Cranial Technologies offers EarWell® treatment to non-surgically correct infant ear shapes. With over 600,000 successful results, EarWell® represents a proven, non-invasive solution for families.We are actively seeking a dedicated full-time Registered Nurse to join our team in Sacramento, CA.

Cranial Technologies stands as the sole organization globally devoted to the research and treatment of plagiocephaly, commonly known as flat head syndrome. With a remarkable track record of successfully treating over 300,000 infants, we are recognized as the experts in this field and a leader in pediatric cranial shaping orthoses.Additionally, Cranial Technologies offers the innovative EarWell® treatment to address infant ear shape corrections without the need for surgical intervention. Having achieved over 600,000 successful outcomes, EarWell® serves as a trusted, non-invasive solution for families.We are excited to announce an opportunity for a dedicated full-time Occupational Therapist to join our growing team in Sacramento, California. This position offers a chance to make a significant impact on the lives of infants and their families.

At Orca Bio, we are committed to transforming the lives of individuals battling blood cancer. Our innovative approach to allogeneic stem cell transplants is setting new standards in the biotechnology industry. We specialize in developing advanced cell therapies that aim to improve survival rates while minimizing the risks associated with traditional procedures, such as graft vs. host disease. Our goal is to not only restore patients' blood and immune systems but also to revitalize their lives through our high-precision investigational therapies.As a Training Specialist, you will play a pivotal role in crafting, executing, and refining both classroom and hands-on training programs tailored to enhance skills related to Good Manufacturing Practice (GMP) operations within a commercial manufacturing setting. Your efforts will ensure that our personnel are thoroughly trained on standard operating procedures (SOPs), equipment usage, safety protocols, and regulatory compliance, all aimed at achieving our production objectives while upholding the highest quality standards.

Join Orca Bio, a pioneering late-stage biotechnology company, dedicated to transforming the lives of individuals battling blood cancer. Our mission is to redefine the transplant process through innovative next-generation cell therapies, significantly improving survival rates while minimizing risks associated with traditional methods, such as allogeneic stem cell transplants. We aim to restore not just patients' blood and immune systems but their lives. Our state-of-the-art manufacturing facility, spanning 100,000 square feet in Sacramento, CA, is crucial to advancing our clinical pipeline and ensuring the reliable delivery of our high-precision cell therapy products. As a key player in our Quality Assurance team, the Quality Assurance Technician will be instrumental in supporting the production of our life-saving therapies by ensuring compliance with stringent quality standards and cGMP regulations. This role involves direct oversight on the production floor, conducting real-time documentation reviews, and collaborating closely with manufacturing and technical teams to swiftly identify and resolve any issues. You will work alongside Manufacturing, Quality Control (QC), and other Quality functions to maintain seamless operations within a highly regulated environment.

About Orca Bio Orca Bio is a late-stage biotechnology company focused on transforming stem cell transplants for blood cancer patients. The team develops next-generation cell therapies designed to improve survival rates and reduce risks like graft versus host disease. With a 100,000-square-foot manufacturing facility in Sacramento, CA, Orca Bio supports both clinical trials and future commercial distribution of its therapies. Role Overview: Quality Assurance Specialist (Weekend Shift) This Quality Assurance Specialist role covers the weekend shift: Friday through Monday. The position plays a key part in maintaining Orca Bio’s quality policy and ensuring that cell therapy products meet rigorous standards before release. What You Will Do Manage and maintain quality systems, including production records and deviation management Oversee processes for deviations, change control, and corrective and preventive actions (CAPA) Handle document management to ensure accurate and compliant record-keeping Make timely batch disposition decisions to support rapid product processing and release Help uphold compliance with internal quality standards and regulatory requirements Location and Shift Details Location: Sacramento, CA Schedule: Friday through Monday (weekend shift) Impact This role directly supports the delivery of innovative cell therapies, contributing to better outcomes for patients facing blood cancers. Learn More For more on allogeneic stem cell transplants, see the Mayo Clinic overview.

Over one million individuals in the United States are currently battling blood cancer. Although allogeneic stem cell transplants have historically provided hope, they can also lead to severe complications, including fatal outcomes and conditions like graft versus host disease. At Orca Bio, a pioneering late-stage biotechnology firm, we are revolutionizing the transplant landscape by developing advanced cell therapies aimed at significantly enhancing survival rates while minimizing risks. Our innovative, high-precision investigational cell therapies are designed not only to replace patients' blood and immune systems with healthy ones but also to restore their quality of life.Our cutting-edge 100,000-square-foot manufacturing facility located in Sacramento, CA, is crucial for ensuring the consistent and reliable delivery of our high-precision cell therapy products. This facility plays a vital role in advancing our clinical pipeline and supporting the future commercialization of our life-saving therapies.Didn’t find a specific role that seems like the ideal match? We still welcome your application. Orca Bio is rapidly expanding, and we are constantly on the lookout for passionate and driven individuals eager to help us shape the future of cell therapy at our Bay Area and Sacramento locations, as well as in certain remote or field-based roles.This general application serves as an opportunity for you to introduce yourself to our Recruitment Team. Please submit your resume along with a brief note detailing your interests and how you envision contributing to Orca Bio. We will keep your information on file and reach out when a suitable opportunity arises, now or in the future.Thank you for your interest in becoming part of our team!What We OfferEligible candidates may receive pre-IPO equity, along with:- Competitive medical, dental, and vision benefits- Flexible paid time off and holidays- 401(k) retirement plan- Life and accidental death & disability insurance- Parental leave benefits- Complimentary daily lunches and snacks at our facilities

Join our dynamic team at 360itprofessionals1 as a Data Analyst in Sacramento, CA! We are looking for analytical thinkers with a passion for data interpretation and insights. As a Data Analyst, you will be responsible for collecting, processing, and analyzing data to help drive strategic decision-making within our organization.Your role will involve collaborating with various departments, providing actionable insights, and contributing to the overall success of our projects. If you have a strong background in data analytics and a desire to make an impact, we want to hear from you!

Orca Bio develops precision cell therapies for blood cancer, with a focus on improving allogeneic stem cell transplants. The Sacramento, CA site plays a critical role in manufacturing these therapies and supporting clinical trials. Role overview The Quality Assurance Specialist (Day Shift) helps maintain high standards for product safety and compliance. This position manages key quality systems and ensures that each batch meets required specifications before release. What you will do Oversee quality systems, including deviation management, change controls, CAPA (corrective and preventive actions), and document management Review and manage production records Make timely batch disposition decisions to uphold quality standards before product release Support efficient processing timelines for cell therapy products Impact This role directly supports the delivery of safe, high-quality cell therapy products to patients in clinical trials, helping Orca Bio advance its mission and meet critical timelines.

Join our dynamic team at 360 IT Professionals as an Electrical Substation Engineer in the vibrant city of Sacramento, California. This is an exciting opportunity to work on cutting-edge electrical projects that shape the future of energy distribution.

Join us at Orca Bio, where we are pioneering innovative cell therapies that aim to transform the transplant process for individuals battling blood cancer. Our mission is to enhance survival rates while minimizing risks through our advanced, high-precision investigational treatments that restore healthy blood and immune systems.The Materials and Cold Chain Operations Supervisor plays a crucial role in overseeing the daily operations related to the supply, handling, cryogenic storage, and cold chain logistics for cell therapy drug products. This position ensures that all activities comply with Good Manufacturing Practices (GMP) and meet regulatory standards for the safe and accurate handling, storage, packaging, and distribution of materials.The supervisor will lead a dynamic team of material handlers and specialists in cryogenic processing and packaging, focusing on maintaining operational readiness, controlling inventory, and ensuring timely shipment of essential materials and patient-specific drug products.Day Shift Hours: 7:00 AM – 3:30 PMCoverage: Core business hours with early escalations as needed.Work Week Schedule: Monday - FridayPlease note there will be an on-call rotation between Day Shift and Night Shift supervisors to guarantee coverage during off-hours (3:30 PM - 10 PM and weekends).

Role overview Terabase Energy is hiring an IT Infrastructure Engineer in Sacramento, CA. This position focuses on designing, deploying, configuring, and supporting both IT and Operational Technology (OT) infrastructure for SCADA systems used in utility-scale solar and battery energy storage projects. The engineer will help maintain the reliability, security, and scalability of infrastructure across several domains, including SCADA servers, virtualization platforms, networking, cybersecurity, remote access, storage, backups, and field connectivity. Close collaboration with teams in SCADA engineering, controls, project management, supply chain, product engineering, and IT operations is required to standardize, deploy, and support infrastructure that meets project schedules and customer requirements. Main responsibilities Design, configure, and support SCADA infrastructure components, such as servers, storage, network switches, firewalls, remote access systems, virtualization platforms, and backup systems for large-scale PV and BESS projects. Oversee the architecture and lifecycle management of Windows-based SCADA environments, including domain structures, user access, patching, antivirus, endpoint hardening, and system recovery. Implement and maintain virtualization solutions (Hyper-V, VMware), including VM creation, template management, resource allocation, performance tuning, and migrations. Configure and troubleshoot industrial and enterprise networking: VLANs, routing, switching, firewalls, VPNs, NAT, cellular modems, and secure remote access for project sites and engineering environments. Support SCADA application hosting environments, including server readiness, redundancy, historian storage, NAS/SAN integration, backup and restore, and disaster recovery planning. Develop and maintain standard infrastructure architectures, documentation, network diagrams, BOM inputs, installation standards, and commissioning support procedures. Collaborate with SCADA software, controls, and commissioning teams to ensure infrastructure is ready for FAT, eFAT, HIL testing, site deployment, and ongoing operational support. Troubleshoot infrastructure issues during integration, FAT, commissioning, and post-COD support, including server performance, network connectivity, remote communications, and cybersecurity controls. Work with supply chain and manufacturing teams to define standard hardware, manage procurement inputs for infrastructure, and improve build quality and repeatability.