Senior Program Manager at 10x Genomics | Pleasanton, California

About The Role Join our innovative Program Management team at 10x Genomics in Pleasanton, where we are dedicated to revolutionizing the field of biology. As a Senior Program Manager, you will collaborate with a dynamic group of biologists, chemists, engineers, computational biologists, and software developers to create groundbreaking products. Our cutting-edge solutions empower researchers to explore biological systems with unmatched resolution and scale, uncovering insights across diverse disciplines including cancer biology, immunology, neuroscience, and developmental biology. In this role, you will lead high-energy, cross-functional teams focused on delivering vital new instruments and consumables to our customers. Your collaboration with technical leads will be essential in defining and managing program priorities, risks, resources, and schedules, ensuring that adjustments are made as the scientific landscape evolves. Your technical expertise and prioritization skills will facilitate team discussions on project scope and potential pathways. With exceptional communication abilities, you will ensure that all team members are aligned and valued. Your organizational skills will play a critical role in keeping projects on track and ensuring nothing is overlooked. What You Will Be Doing Lead as Program Manager on 10x R&D teams during product development and introduction, directing cross-functional teams to define and commit to appropriate scope, schedule, and budget for optimal scientific and business outcomes. Work closely with technical leads to establish and actively manage program priorities, risks, resources, and schedules, adapting as scientific and development needs change. Oversee daily program operations, ensuring swift identification and resolution of issues utilizing modern program management tools and techniques. Facilitate program communications and phase approval reviews, delivering clear and concise updates to all stakeholders, adapting your communication style for a diverse audience. Utilize advanced AI tools (e.g., Claude, Gemini, Asana AI) to enhance program planning, synthesize complex information, and establish best practices for AI-assisted program management. Evaluate and enhance Program Management workflows and communication processes. Note: This is not an IT or Software project management position.

10x Genomics is growing its diagnostics team, bringing single-cell and spatial genomics technologies into clinical practice. The Clinical Laboratory Scientist (General Supervisor) leads daily operations for high-complexity next-generation sequencing (NGS) testing in the CLIA-certified laboratory at the Pleasanton, California headquarters. This position ensures test results are accurate and timely, upholding rigorous regulatory and quality standards. The supervisor also guides technical staff and helps keep lab operations running smoothly. What you will do Oversee daily laboratory operations for high-complexity NGS assays, following established protocols and quality requirements. Supervise and mentor laboratory staff, including training, competency assessments, and performance reviews. Review quality control data and assay performance to verify accuracy and reliability of test results. Ensure compliance with CLIA, CAP, and other relevant regulatory standards. Contribute to developing, validating, implementing, and improving NGS assays and lab workflows. Monitor laboratory throughput, turnaround times, and resource usage to support efficient operations. Troubleshoot technical issues with instruments, assays, or data analysis. Maintain detailed laboratory records, including SOPs, validation documents, and quality logs. Collaborate with lab leadership on ongoing quality improvement projects. Oversee maintenance and calibration of laboratory equipment. Location This role is based at 10x Genomics headquarters in Pleasanton, California.

The Director of Global Digital Marketing plays a pivotal role in the dynamic digital marketing landscape of 10x Genomics, driving impactful business results and innovating across various channels to maintain our leadership in scientific markets. Reporting to the Vice President of Integrated Marketing Communications, you will be responsible for the strategic planning, execution, and optimization of all digital marketing initiatives, including website management, SEO, SEM, email campaigns, webinars, and digital advertising. This role demands a strategic yet hands-on leader who is dedicated to fostering measurable growth, exceptional digital engagement, and seamless user experiences that enhance product launches, drive demand generation, and elevate brand presence.

About the Role At 10x Genomics, we are proud to announce the establishment of our inaugural CLIA/CAP-certified laboratory, dedicated to integrating advanced single-cell and spatial genomic technologies into clinical settings. As a pivotal member of our team, the Quality Assurance Manager will report directly to the Head of Quality and Regulatory, and will be instrumental in shaping, developing, and executing the laboratory's quality framework. This role ensures adherence to CLIA, CAP, and state-specific (California and New York) regulations. The ideal candidate is a proactive quality assurance professional, capable of independently managing QA responsibilities during the initial phases of lab development, and ultimately leading a small QA team as clinical operations expand. A strong background in clinical laboratory quality systems, coupled with practical, solution-driven execution in a dynamic and collaborative environment, is essential for success in this position.

About the Role: The Mechanical Engineering Intern will play a vital role in assisting the design and analysis of mechanical systems and test fixtures for cutting-edge biotechnology and life sciences instrumentation. This position involves conducting feasibility testing and gathering data on new and revised designs. You will support the R&D engineering team in detailed design preparation for test equipment, test setups, data analysis, and documentation. We are looking for a motivated and meticulous Mechanical Engineering Intern to join our Hardware Engineering team for a 3-month summer internship in 2026. This role is crucial for supporting product testing and validation efforts for our ultra-precision life sciences instrumentation, including components for automation and fluid handling. The ideal candidate will possess a foundational understanding of Mechanical Engineering principles and a strong eagerness to gain hands-on experience in testing, small-scale fixture design, and data analysis. What You Will Be Doing: Test Fixture Design and Modeling: Collaborate in the design and modeling of small mechanical test fixtures using CAD software (SolidWorks) for specific component or system validation in life science instruments. Experimental Execution: Conduct mechanical, thermal, or functional tests on prototypes and existing designs, often requiring precise control of movement or fluids. Data Acquisition and Light Coding: Assist in establishing data logging and instrumentation setups. Perform light coding tasks (e.g., in Python or MATLAB) for data acquisition, reduction, or basic control of test sequences involving sensors and actuators. Data Analysis: Analyze and interpret collected test data to identify performance metrics and areas for improvement, focusing on precision, repeatability, and reliability. Design Support: Work with senior engineers to review test results and suggest minor design updates or modifications based on findings, emphasizing Design for Reliability and Design for Manufacturing (DFM). Documentation: Aid in the preparation of detailed documentation, including test procedures, result summaries, and contributions to documentation. System Understanding: Support testing related to electro-mechanical components, fluidic systems (pneumatic or microfluidic), and structural elements typical in laboratory automation.

At 10x Genomics, we are dedicated to revolutionizing the field of biology. Our mission is not just a statement; it is a commitment to advancing scientific research and discovery. As we navigate through this century of biology, the innovations we bring forth have the potential to create transformative changes in the world. We empower scientists to explore new realms of inquiry, enabling them to pursue scientific questions previously thought unapproachable. Our cutting-edge tools have facilitated groundbreaking research in diverse application areas, including cancer, immunology, and neuroscience. We foster a culture that encourages our team members to ignite their passions, explore innovative ideas, and excel in a collaborative, inclusive environment. We understand that the scientific breakthroughs we support are underpinned by a robust infrastructure of talented professionals who drive the life sciences sector forward, enabling scientists, engineers, clinicians, computational biologists, and others to achieve remarkable advancements. We are committed to recruiting the best talent to enhance every aspect of our organization because the discoveries we make together will lead to improved technologies, enhanced treatments, and a brighter future. Discover how you can make a significant impact at 10x Genomics. This position offers a hybrid work arrangement in Pleasanton, CA. About the Role: We are looking for a highly skilled and motivated Senior Security Engineer (IAM Identity Engineer) to take ownership of our identity and access management systems. This role will primarily focus on enhancing our Okta implementation and fortifying our AWS Identity and Access Management configurations. The ideal candidate will possess extensive knowledge of the Okta platform, a proven track record in configuring SCIM, and significant multi-cloud experience. We recognize the complexities of security and prioritize safeguarding our customers above all else. If you are a proactive individual with a passion for security and thrive in a collaborative environment alongside a diverse team of experts, we invite you to join us at 10x Genomics. As a Senior Security Engineer, you will act as the technical subject matter expert for our identity solutions and cloud configurations. Your responsibilities will include conducting design reviews, performing technical security assessments, and executing access reviews to identify overly permissive policies. You will collaborate with engineering teams to mitigate risks and enhance the overall security of our products. In this security leadership role, you will develop a comprehensive understanding of our products and systems, ensuring that security measures are seamlessly integrated. This position demands both deep and broad technical expertise across various disciplines, combined with a hands-on approach across a diverse range of software.

About the Role At 10x Genomics, we are dedicated to empowering researchers to unravel some of the most complex and elusive questions in biology. Our commercial systems serve as the backbone of our revenue generation, and we are on the lookout for a Senior Product Manager to spearhead the enhancement of our sales technology ecosystem. This position is ideal for a strategic and systems-oriented product leader who possesses exceptional B2B enterprise SaaS expertise to elevate our commercial framework. You will play a pivotal role in designing sophisticated, scalable systems that cater to both B2B enterprise and emerging B2C purchasing experiences. Your primary focus will include the backend architecture and the Salesforce ecosystem, alongside ensuring our internal tools are user-centric. You will advocate for our internal teams' daily experiences, influence system designs, and engage in web projects that interact with our commercial data flow. Key Responsibilities Architect and implement a strategic overhaul of our end-to-end purchasing experience and CRM. Transform complex system needs into a streamlined and scalable architecture. Automate valuable team initiatives by integrating account-based outreach, intent data, and sales enablement tools to reduce manual processes and direct efforts toward the most impactful activities. Develop data models and account hierarchies to support a comprehensive omnichannel commercial strategy, seamlessly handling intricate B2B business models alongside self-service e-commerce options. Collaborate extensively with commercial leadership and engineering teams, translating complex business goals into precise requirements. Promote outstanding UX for internal systems, ensuring that our tools enhance internal teams' efficiency in selling rather than encumbering them with data entry tasks.

About the Role At 10x Genomics, we empower researchers to tackle the most challenging questions in biology. Our innovative commercial systems and software serve as the foundation for engaging and converting global researchers. We are looking for a Senior Product Manager to spearhead the ongoing development of our marketing systems and web platform. This position is ideal for a strategic and decisive product leader who possesses extensive knowledge in B2B growth, custom web application experiences, and a methodical approach to enterprise marketing technology (MarTech) and data architecture. You will collaborate closely with engineering and commercial teams to develop intuitive, self-service web solutions that enhance user satisfaction and accelerate our sales pipeline. Additionally, you will oversee our MarTech ecosystem, designing scalable data pipelines that integrate our custom-built web platform with enterprise tools like Marketo and Salesforce, optimizing both customer acquisition and existing customer engagement. Your Responsibilities Develop a compelling product strategy for our web properties and customer platform, simplifying complex scientific purchasing journeys into user-friendly, self-service experiences that drive new lead acquisition and streamline re-ordering for returning researchers. Oversee our MarTech ecosystem. Conduct a strategic review of our current technology stack, establishing strong operational governance and ensuring seamless data flow between our web frontend, marketing automation, and CRM tools. Leverage data as your creative strength. Utilize web analytics, qualitative insights, and quantitative metrics to validate ambitious ideas, optimize conversion funnels, and secure high-quality marketing intelligence. Define the attribution and routing logic that connects web interactions to sales opportunities using your extensive expertise. Engage deeply with commercial leadership and engineering, translating intricate business objectives into clear requirements. Use your exceptional interpersonal skills to foster consensus on requirements, manage change effectively, and align cross-functional teams around scalable best practices. Design requirements for the necessary data models and workflows to support complex, omnichannel demand generation campaigns across web, email, and paid media.

About the Role: 10x Genomics is seeking an exceptional Senior Scientist to join our Process Development team. This pivotal role supports the development and commercial launch of innovative new products. The successful candidate will collaborate across various teams, including Chemistry, Microfluidics, custom plastic consumables, Assay Development, and Production, to develop, optimize, validate, and transfer novel chemistries and processes essential for producing 10x reagents and consumables. A comprehensive understanding of chemical processes and analytical methods related to polymer, surfactant, or surface chemistry is crucial, along with hands-on experience in custom instrumentation and a background in process development, scale-up, implementation, and validation within a commercial manufacturing environment. The ideal candidate is a self-starter, a strategic thinker, action-oriented, and adaptable to shifting priorities and methodologies. You should flourish in a dynamic environment, excel at managing multiple tasks, and effectively communicate across all organizational levels, providing immediate and impactful contributions.

Position Overview The Senior Strategic Product Marketing Manager plays a pivotal role within the Marketing Strategy team at 10x Genomics. This senior-level position serves as the chief architect for the positioning and market introduction of 10x Genomics’ groundbreaking innovations. You will harmonize long-term vision with market readiness, ensuring that product strategies are in sync with overarching business goals and yield measurable market results. This is a highly collaborative role that connects Product Management, Portfolio Strategy, and Integrated Marketing teams. You will distill complex scientific and technical features into compelling value propositions that resonate with target audiences in the single-cell and spatial biology sectors. Key Responsibilities: Strategic Positioning and Messaging Positioning Development: Create engaging, customer-focused product positioning and campaign themes. Scientific Translation: Convert intricate technical and scientific product features into clear, benefit-driven narratives for targeted audiences. Differentiation: Identify and validate unique selling points in relation to the competitive landscape. Go-To-Market (GTM) Leadership Launch Ownership: Spearhead the development and planning of global GTM strategies for new product introductions (NPIs). Commercial Readiness: Establish launch objectives, timelines, and deliverables to ensure organizational preparedness for market entry. Strategic Alignment: Collaborate with Product Management to ensure that the roadmap meets market demands and work with the Integrated Marketing team to execute campaign launches. Sales Enablement and Field Readiness Asset Creation: Produce strategic sales materials, including pitch decks, market comparisons, and objection-handling guides. Training: Design and deliver training sessions to empower field and channel teams to effectively convey product value.

About the Role Join 10x Genomics as a Senior Systems Engineer, where you will play a pivotal role in the entire product development lifecycle, from conceptualization to launch. You will be responsible for developing instrument architectures, creating and executing system-level models, and designing and implementing custom hardware systems along with their metrology and testing strategies. Collaborating closely with hardware engineers across mechanical, electrical, optical, and fluidic disciplines, you will also work in tandem with software, chemistry, and computational biology teams. The ideal candidate is a highly motivated, independent thinker with a systemic approach to engineering challenges. You value innovative and reliable design while enjoying the interdisciplinary nature of your work. Strong data analysis and presentation skills are essential, alongside a solid technical background in instrument hardware and/or software design. A proven track record in hardware development, system integration, and testing is crucial for success in this role.

Join our dynamic finance team as a Senior Accountant, where you will play a crucial role in managing financial operations and ensuring compliance with accounting standards. You will be responsible for preparing financial statements, conducting audits, and providing insightful reports to drive business decisions. Collaborate closely with cross-functional teams to enhance financial processes and contribute to the overall success of Tekion.

About the Role:The Senior Manager, Clinical Operations and Strategic Alliances, under the guidance of the Director of Business Development and Strategic Partnerships, will spearhead the operational execution and strategic oversight of pivotal alliances that are essential to 10x Genomics’ mission of advancing innovative diagnostic solutions utilizing single-cell and spatial technologies.Key responsibilities encompass managing a portfolio of academic collaborations and strategic partnerships, ensuring alignment with established milestones and outcomes. You will lead the operational execution of extensive, multi-year collaborations with leading academic institutions, generating critical evidence for future clinical applications of our technologies. Additionally, you will facilitate collaboration between internal cross-functional teams and external partners to drive desired outcomes efficiently.This position requires a distinctive combination of Clinical Operations and Alliance Management. The ideal candidate will be an action-oriented, results-driven leader with prior experience in managing clinical research studies and strategic partnerships.What You Will Be Doing:Clinical Operations and Study ExecutionStudy Execution: Oversee the operational execution of large-scale, longitudinal clinical research studies, adhering to established agreements with academic institutions.Timeline & Risk Management: Own the clinical research study timelines, deliverables, and operational plans, ensuring compliance with sampling schedules; proactively identify operational risks related to enrollment, setup, or logistics, implementing mitigation strategies to uphold study integrity.Sample Logistics & Chain of Custody: Develop and enforce auditable procedures for sample collection, tracking, and chain of custody, ensuring compliant transport from clinical sites to 10x Genomics laboratories.Budget & Resource Oversight: Manage study budgets, including oversight of reimbursements, equipment provisioning, and consumables provided to partner sites.Regulatory & Quality Compliance: Ensure full compliance of all study activities with IRB protocols, patient consent requirements, and GCLP/CLIA standards where applicable.Strategic Alliance Management

Join our dynamic team as a Retail Merchandiser in Pleasanton! In this role, you will be responsible for enhancing the shopping experience by ensuring product availability and visual appeal on shelves. You will collaborate with store management to implement merchandising strategies that drive sales and customer satisfaction.

About the Role At 10x Genomics, we are pioneering advancements in diagnostics by harnessing our cutting-edge single-cell and spatial assay technologies for transformative clinical applications. We are currently looking for a Scientist II to become an integral part of our clinical bioinformatics team. The ideal candidate will be adept at translating intricate biological questions into effective computational strategies, employing computational and statistical methodologies to analyze extensive single-cell or spatial transcriptomics datasets to extract clinically relevant insights. This role necessitates a biology-first approach, expertise in large-scale bioinformatics analysis, and a strong foundation in scientific reasoning and statistical analysis. The successful candidate will have the chance to work with some of the largest biomedical datasets, using state-of-the-art 10x Genomics technologies to drive innovations in clinical diagnostics. What You Will Be Doing: Execute comprehensive computational and statistical methods for single-cell and spatial transcriptomics data analysis. Extract actionable insights from clinical and translational single-cell or in-situ spatial datasets. Design, implement, and validate biomarkers for diagnostic use. Develop and uphold bioinformatics pipelines for reproducible, large-scale data processing. Process and analyze single-cell or in-situ spatial transcriptomics datasets encompassing hundreds to thousands of samples. To Be Successful, You Will Need: A Ph.D. in bioinformatics, computational biology, genomics, or a related field, along with substantial hands-on experience in single-cell NGS data analysis. At least 2 years of relevant industry experience post-Ph.D. Proficiency in analyzing large-scale single-cell or spatial transcriptomics datasets to glean biologically significant insights and/or diagnostic biomarkers. A deep understanding of the assumptions, limitations, and caveats associated with statistical methods. Experience in developing and optimizing high-performance, scalable code. Proficiency in a Linux environment. A goal-oriented, self-driven mindset with a knack for independent problem solving. Exceptional attention to detail and a strong work ethic.

Location: Pleasanton, California, USA (HQ). Primarily onsite; some flexibility considered. Role Overview 10x Genomics is looking for a Director of Human Resources Business Partner to support the Research and Development (R&D) division. This leader will shape talent management strategies and work closely with senior R&D leaders on decisions that affect organizational structure, leadership development, and team culture. The Director will model strong HR partnership and help set the tone for the HR Business Partner team. What You Will Do Advise R&D senior leaders on talent management, organizational design, and leadership development. Build trust and become a key resource for leadership on critical HR decisions. Coach colleagues through complex or ambiguous situations, providing clear, constructive guidance. Promote a culture where teams can do their best work and grow. Set standards for collaboration within the HR Business Partner group. Who We’re Looking For Experience navigating ambiguity and challenging senior leaders constructively. Comfort coaching others through complex scenarios. Data-driven mindset with the ability to make timely, informed decisions under pressure. Focus on long-term solutions and organizational health. Ability to work onsite regularly in Pleasanton, CA, with some flexibility as needed. Reporting This position reports to the Senior Director of Global HR Business Partners.

Join Calyxo as a Senior Manager, Sourcing and Procurement in Pleasanton, CA, where you will lead strategic sourcing initiatives and drive procurement excellence across the organization. You will collaborate with cross-functional teams to optimize supply chain processes, negotiate contracts, and ensure the timely delivery of high-quality materials.Your expertise will be pivotal in identifying cost-saving opportunities and implementing best practices in sourcing and procurement.

About the IT Internship bkf engineers is looking for an IT Intern in Pleasanton, California for 2026. This internship puts students alongside experienced IT professionals, supporting projects that keep the company’s technology running smoothly. Interns will see first-hand how an engineering firm manages and improves its tech infrastructure. What You Will Do Work with the IT team on projects that support and improve company systems Apply classroom knowledge to practical challenges in a real engineering setting Contribute to solutions that help the business operate more efficiently Location Pleasanton, California, United States

About the Role: Join 10x Genomics in our mission to revolutionize diagnostics by leveraging our pioneering single-cell and spatial genomics technologies for impactful clinical applications. We are currently looking for a talented and driven Senior Scientist to become a key member of our Diagnostic Assay Development team. This role is a hands-on bench scientist position that involves taking scientific ownership of assay development and optimization while providing mentorship and technical guidance to junior staff. As a Senior Scientist, you will execute, troubleshoot, and enhance 10x Genomics-based assays to facilitate the development of robust Laboratory Developed Tests (LDTs). Key Responsibilities: Assay Development & Execution Independently perform complex single-cell and spatial genomics workflows, including sample processing, library preparation, and sequencing. Act as a hands-on technical authority for 10x Genomics platforms (e.g., Chromium, Xenium), ensuring high standards in assay performance. Methodically troubleshoot and refine assay workflows to enhance robustness, sensitivity, and reproducibility. Adapt, refine, and expand existing protocols to fulfill clinical, regulatory, and scalability criteria. Design and conduct feasibility studies to assess new reagents, chemistries, instrumentation, and workflow enhancements. Process a variety of challenging clinical sample types to support clinical research and validation studies. Analytical Validation & Documentation Design and implement experiments that support analytical validation, focusing on accuracy, precision, detection limits, and reproducibility. Create, review, and uphold high-quality laboratory documentation, including SOPs, validation protocols, and batch records, in compliance with Good Documentation Practices. Analyze assay performance metrics and quality control data to drive informed, data-based technical decisions. Present experimental data and scientific findings clearly in team meetings and written reports. Scientific Leadership & Mentorship Provide daily technical guidance and mentorship to junior team members. Review experimental data and assist in the interpretation of results to foster a collaborative research environment.

10x Genomics is developing a diagnostics program that brings single-cell and spatial genomics technologies to clinical settings. The Clinical Laboratory Scientist (Technical Supervisor) will oversee scientific and technical operations for complex next-generation sequencing (NGS) assays in the company’s CLIA-certified laboratory at headquarters in Pleasanton, California. This position ensures that NGS testing is accurate, meets analytical and regulatory standards, and operates smoothly. As the technical lead, the supervisor acts as an expert in assay validation, quality systems, and troubleshooting, partnering with lab leadership to uphold standards and drive ongoing improvements. Main Responsibilities Direct daily operations and technical aspects of complex NGS assays to deliver accurate and reliable results. Validate and implement NGS assays in compliance with CLIA, CAP, and other regulatory requirements. Establish and monitor quality control and assurance programs by analyzing performance data, identifying trends, and initiating corrective actions as needed. Draft, review, and approve technical documents, including standard operating procedures (SOPs), validation protocols, reports, and testing methods. Maintain regulatory compliance and support both internal and external audits and inspections. Act as the primary technical contact for resolving complex issues related to assays, laboratory instruments, and bioinformatics. Review and approve changes to assays, workflows, instruments, and software, and oversee any required revalidation. Manage proficiency testing, method comparisons, and ongoing monitoring of assay performance. Provide technical training and assess competency of laboratory staff. Collaborate with teams in bioinformatics, R&D, quality, and operations to improve and optimize assays. Stay current with new technologies, regulatory updates, and best practices in NGS and molecular diagnostics.