Staff Principal Engineer Technical Mitigations Research jobs in Cambridge – Browse 472 openings on RoboApply Jobs
Staff Principal Engineer Technical Mitigations Research jobs in Cambridge
Open roles matching “Staff Principal Engineer Technical Mitigations Research” with location signals for Cambridge. 472 active listings on RoboApply Jobs.
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Staff / Principal Engineer, Technical Mitigations Research
Lila SciencesCambridge, MA USA; London, UK; San Francisco, CA USA
On-site Full-time
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We are seeking candidates with a strong engineering background, preferably with a focus on technical mitigations. Experience in research and development, along with a passion for solving complex problems, is essential. Ideal candidates will have a proven track record of successful project execution and the ability to work collaboratively within a multidisciplinary team.
About the job
Join Lila Sciences as a Staff or Principal Engineer specializing in Technical Mitigations Research. This role offers an exciting opportunity to leverage your engineering expertise to develop innovative solutions in the field of technical mitigations.
About Lila Sciences
Lila Sciences is at the forefront of innovation, dedicated to transforming the landscape of scientific research. Our mission is to push the boundaries of technology and create impactful solutions that contribute to the advancement of science and health.
Full-time|On-site|Cambridge, MA USA; London, UK; San Francisco, CA USA
Join Lila Sciences as a Staff or Principal Engineer specializing in Technical Mitigations Research. This role offers an exciting opportunity to leverage your engineering expertise to develop innovative solutions in the field of technical mitigations.
Full-time|$224K/yr - $336K/yr|On-site|Cambridge, MA USA; San Francisco, CA USA
Your Impact at Lila As a Senior or Principal Research Engineer specializing in Synthetic Data, you will play a pivotal role in shaping the vision, roadmap, and execution of our synthetic data initiatives. Your responsibilities will span from asset generation and simulation to integrating machine learning training and achieving measurable enhancements in model performance. Collaborating closely with our Research Engineering team, you will design, generate, and implement artificial datasets aimed at training, testing, and refining Lila’s platform to achieve our strategic objectives. What You Will Build Define and refine the synthetic data strategy along with a comprehensive multi-quarter roadmap. Create evaluation frameworks that effectively connect synthetic interventions with genuine model performance. Establish high standards for asset quality, diversity, thorough documentation, and reproducibility while fostering a robust review culture. What You Will Need to Succeed Over 6 years of experience in applied ML/ML systems, with at least 3 years leading industry initiatives, showcasing a strong track record in advanced algorithms and frameworks designed for large-scale synthetic data generation. More than 8 years of experience working with contemporary ML workflows, including Python, PyTorch, dataset tools, training loops, and evaluation frameworks; adept at profiling and optimizing GPU-intensive pipelines. Bonus Points For A proven history of constructing synthetic datasets from source data to significantly enhance model performance in specific domains. Experience with instruction fine-tuning and hill-climbing techniques. Ability to translate product requirements and feedback into a scalable synthetic data generation pipeline. Knowledge of quantization, distillation, routing, mixture-of-experts, and cost optimization at scale. Experience in compliance-heavy settings (HIPAA, PCI, FedRAMP) and with on-premises/VPC deployments. About Lila Lila Sciences stands at the forefront of innovation as the world’s first scientific superintelligence platform and autonomous lab, dedicated to life sciences, chemistry, and materials science. We are ushering in an era of limitless discovery by harnessing AI to enhance every facet of the scientific method. Our mission is to empower scientists to tackle humanity's most pressing challenges in health, climate, and sustainability at an unprecedented pace and scale. Discover more about our mission at www.lila.ai. If this sounds like an environment in which you would thrive, we encourage you to apply even if your experience doesn't perfectly align with every requirement listed.
Harvard University is hiring a Principal Research Scientist in the Sciences - Chemistry and Chemical Biology department based in Cambridge. This position guides research activities and partners with faculty and other scientists to deepen knowledge in chemistry and chemical biology. Key responsibilities Lead research projects focused on chemistry and chemical biology topics Work with faculty and research teams to design experiments and analyze results Use new approaches to solve challenging scientific problems Support the creation of scientific papers and presentations
Join our dynamic team at Ramboll as a Senior / Principal Electrical Engineer. In this role, you will lead innovative projects, collaborate with a talented team, and contribute to the development of sustainable electrical solutions. Your expertise will be pivotal in driving forward our commitment to excellence in engineering.
The Center for Nanoscale Systems at Harvard University is hiring a Research and Innovation Engineer based in Cambridge. This role supports collaborative research efforts focused on nanoscale systems and their use across various scientific disciplines. Role overview As a Research and Innovation Engineer, work will involve partnering with teams from different backgrounds to move research projects forward. The position centers on nanoscale systems, contributing to studies and developments that span several areas of science. Collaboration This role requires regular interaction with interdisciplinary groups, facilitating progress and innovation in ongoing projects. The work environment values teamwork and the exchange of ideas between researchers from diverse fields.
Full-time|$167.2K/yr - $209K/yr|On-site|Cambridge, MA
Join Cambridge Mobile Telematics (CMT), the world's leading telematics service provider, dedicated to enhancing road safety and improving driver behavior. Our cutting-edge AI platform, DriveWell Fusion®, integrates sensor data from millions of IoT devices—including smartphones, proprietary Tags, connected vehicles, dashcams, and third-party devices—melding it with contextual information to deliver a comprehensive analysis of vehicle and driver interactions. Our insights empower auto insurers, automotive manufacturers, mobility companies, and public sector organizations to optimize risk assessment, safety protocols, claims processing, and driver improvement initiatives. Based in Cambridge, MA, with global offices in Budapest, Chennai, Seattle, Tokyo, and Zagreb, CMT actively monitors and safeguards millions of drivers worldwide every day.As a Principal Software Engineer within our Trip Processing team, you will play a crucial role in delivering innovative technical solutions at the core of our advanced telematics pipeline. Collaborating closely with product and research teams, you will design, develop, and implement new features while mentoring junior engineers and enhancing our codebase. Your contributions will be vital in upholding our high standards of software quality to meet the expectations of our insurance partners.We seek a collaborative, customer-focused, and imaginative Principal Software Engineer II - Backend who is eager to help make roads safer and drivers more responsible!
Join Harvard University as a Research Infrastructure and Software Engineer, where you will play a pivotal role in enhancing research capabilities through innovative software solutions. Collaborate with cross-functional teams to design, implement, and maintain robust infrastructure that supports diverse research initiatives. Your expertise will enable researchers to focus on their work while you ensure seamless access to data and resources.
POS-4092 Team and Product Focus The Data Hub team at HubSpot connects scattered data sources to deliver practical insights for Revenue Operations, marketing, sales, and customer teams. By integrating information from various channels and tools, the team improves data quality and makes this data actionable within HubSpot. This enables teams to run AI-powered demand generation, optimize campaigns, and produce reliable reports, without requiring deep expertise in data systems. Product engineering here blends data engineering, machine learning, applied AI, and market strategy. The group prioritizes reliability, cost efficiency, and scalability, while always considering usability for marketers and sales professionals. Role Overview HubSpot is seeking a Lead Principal Software Engineer to steer the next phase of Data Hub's development. This platform is evolving into the central engine for data-driven demand generation company-wide. Key Responsibilities Take ownership of critical components in the data lake and analytics architecture, working with technologies such as Iceberg, Spark, and both batch and streaming data pipelines. These systems underpin large-scale demand generation, segmentation, and scoring. Design and refine data systems to achieve the right balance between cost, latency, data freshness, and reliability. Apply principles like the CAP theorem, efficient partitioning, and thoughtful storage layout to guide decisions. Collaborate closely with Product Management, product analytics, and go-to-market leaders to deliver solutions that drive business outcomes: improved lead scoring, enhanced funnel visibility, audience segmentation, and campaign attribution for marketing and sales. Contribute to transforming Data Hub into an AI-powered platform, aiming for curated, always-available datasets that support AI agents and reporting tools, eliminating the need for manual integrations or custom pipelines. This is a hands-on principal engineering position. The role involves building systems, working alongside product and design, and amplifying the impact of HubSpot's broader engineering community.
Full-time|$171K/yr - $230.5K/yr|On-site|Cambridge, MA USA
Role Overview Lila Sciences is seeking a Principal Engineer with expertise in AI Security for its Cambridge, MA office. This senior individual contributor will help define and drive the technical strategy to secure AI applications across the organization. The role involves close collaboration with IT and business teams to ensure AI tools and platforms are implemented safely and in compliance with internal and external requirements. Securing both third-party and in-house AI tools is central to this position. The work will focus on protecting sensitive data, intellectual property, and scientific processes as AI becomes increasingly embedded in Lila's operations. What You Will Do Enterprise AI Security Strategy: Develop and roll out security controls and guidelines for using AI tools throughout the company, covering LLM APIs and SaaS AI platforms. AI Gateway & Agentic Gateway Security: Design and enforce controls for AI gateways, monitoring and managing access to AI systems. Ensure agentic workflows are secured with strong identity and authorization measures. AI Red Teaming & Adversarial Testing: Lead red teaming and adversarial testing efforts to uncover vulnerabilities in AI usage, such as prompt injection and data exfiltration risks. Data Protection for AI Usage: Establish and maintain safeguards to prevent sensitive data exposure through AI systems, with a focus on input/output filtering and secure data management. Multi-Layer AI Security: Integrate AI security practices with the organization's broader security framework, maintaining visibility and control over AI service access and data flows. AI Threat Modeling: Build and maintain threat models tailored to enterprise AI applications, addressing risks like data leaks and unauthorized agent actions. Vendor & Platform Security: Assess and advise on secure integration of third-party AI vendors, with close attention to their data handling practices and model behavior.
Full-time|$163.4K/yr - $228K/yr|On-site|Cambridge, MA USA
Your Impact at Lila Sciences Lila Sciences is on the lookout for a highly skilled Staff/Principal Mechanical Engineer to enhance our Hardware & Controls Engineering team. The specific title—Staff or Principal—will align with your level of experience and expertise. As a pivotal technical leader, you will apply your extensive knowledge to design and develop components for workcell robotics, mechanical systems, and automation within the realms of life sciences and physical sciences. You'll collaborate with a diverse team of experimental scientists, AI/ML specialists, software engineers, and process automation experts to spearhead intricate projects, mentor multidisciplinary teams, and deliver cutting-edge automation solutions. What You Will Be Creating Oversee the design and execution of bench-scale robotics and mechanical systems for advanced automation in life science and physical science applications. Craft innovative pneumatic, electro-mechanical, and optical solutions tailored for state-of-the-art robotic workcells utilized in biological research and materials discovery. Lead and mentor teams in advanced CAD design and analyses using SolidWorks, optimizing systems for high-throughput workflows. Manage the creation and validation of designs through rapid prototyping techniques such as 3D printing and laser cutting. Facilitate cross-functional collaborations to seamlessly integrate mechanical designs with software and controls across scientific fields. Devise strategies to convert manual processes into automated workflows while adhering to stringent safety and quality standards. Coordinate with external suppliers for bespoke component development and system integration. What You Need to Succeed A Bachelor's or Master's degree in Mechanical Engineering, Robotics, or a related discipline. 8+ years of mechanical engineering experience, showcasing proven expertise in life science and physical science automation (title will be aligned with experience & expertise). Extensive proficiency in SolidWorks CAD design, GD&T, and DFMA methodologies. In-depth experience utilizing requirement management systems, product lifecycle management, and product data management systems. Proven leadership in managing complex projects and mentoring engineering teams. Bonus Points For Significant experience in automation across scientific disciplines, with a strong command of SolidWorks CAD design, PDM, and related technologies.
Full-time|$163.4K/yr - $228K/yr|On-site|Cambridge, MA USA
Your Impact at Lila Lila Sciences is on the lookout for a talented Industrial Engineer to take the lead in designing and optimizing the physical layout of our cutting-edge AI Science Factories. In this pivotal role, you will integrate laboratory instrumentation and robotics into a seamless and efficient factory design. Your collaboration with hardware engineering, scientific teams, robotics, facilities, and operations will be crucial in creating layouts that prioritize safety, scalability, and high-throughput autonomous research. This position is vital for translating intricate cross-functional requirements into a factory environment that propels Lila’s next-generation scientific capabilities. What You'll Be Building Take ownership of the complete factory layout, focusing on spatial planning, adjacency mapping, and utility requirements. Integrate diverse lab instrumentation layouts from various scientific and engineering domains into a cohesive, high-performance factory design. Work closely with teams in hardware, robotics, science, automation, safety, and facilities to incorporate essential requirements for utilities, safety, accessibility, maintenance, and environmental controls. Create and maintain precise 2D and 3D CAD models of the entire factory layout, managing version control and change updates effectively. Collaborate with robotic teams to conduct simulations and scenario analyses, evaluating throughput, operational efficiency, and identifying bottlenecks. Partner with construction, facilities, and external vendors to ensure that physical buildouts accurately reflect intended designs and are scalable to meet future demands. Develop standards, documentation, and layout guidelines for new lab instrumentation and factory expansions. What You’ll Need to Succeed Bachelor’s or Master’s degree in Industrial Engineering, Mechanical Engineering, Manufacturing Engineering, Systems Engineering, or a related field. Proven experience in designing factory, laboratory, or production layouts in complex environments. Expertise in CAD tools (e.g., AutoCAD, REVIT, SolidWorks). Strong knowledge of workflow optimization, material flow, ergonomics, and spatial systems. Ability to work collaboratively across multidisciplinary engineering and scientific teams. Exceptional communication and documentation skills.
Join Riverlane as a Staff Testing Engineer in Cambridge, UK. This is a full-time, permanent position offering a hybrid working model.Salary: £95,000 to £120,000, depending on experience, plus bonus and benefits.We offer a competitive salary range based on the candidate's experience, industry knowledge, and relevant skills. Every offer will be tailored to reflect the applicant's background and accomplishments.Part-time applications are welcome. Please indicate your preferred working schedule in your cover letter.About RiverlaneAt Riverlane, we are on a mission to revolutionize quantum error correction (QEC) to facilitate a new era of technological advancement. Our work spans various fields, including material and climate science and drug design simulations, showcasing the potential of quantum computing in addressing humanity's grand challenges. As the leading organization in QEC technology, we are committed to overcoming the industry's most significant technical challenges.With over $125M in funding, we are accelerating our pioneering research and development in QEC and collaborating with top quantum hardware companies and government entities to make fault-tolerant quantum computing a reality.
Location: Cambridge, UK | Employment Type: Full-time | Contract Type: Permanent | Work Arrangement: HybridSalary Range: £90,000 to £115,000 depending on experience + Bonus + BenefitsWe are open to considering part-time applications for this role. Please specify your preferred working hours in your cover letter.About UsAt Riverlane, we are on a mission to master quantum error correction (QEC), paving the way for breakthroughs in material science, climate science, and drug design. Quantum computers are set to tackle some of humanity's most pressing challenges, and we are proud to lead the industry in QEC technology. Our team thrives on a blend of expertise, innovation, and passion, which are essential to overcoming this complex problem. With over $125M in funding, we collaborate with top global quantum hardware providers and government agencies to make fault-tolerant quantum computing a reality.
POS-31591About Our TeamThe Prospecting Solutions team is revolutionizing the way B2B SMB and mid-market sales teams cultivate their pipeline. The current outbound sales approach is often inefficient and outdated, with representatives dedicating excessive time to research, tool integration, and uncertain contact strategies. Our focus transcends mere outreach execution; we prioritize intelligent sourcing, prioritization, and trust.This team is developing a comprehensive, signal-driven prospecting ecosystem that aligns with contemporary B2B purchasing behavior: account-centered, aware of buying groups, and trust-oriented. Our mission is to merge human discernment with automation, enabling sales teams to generate consistent, high-quality pipeline without compromising their brand integrity or their representatives' well-being.About the RoleWe are seeking a Principal Software Engineer to serve as a pivotal technical leader for Prospecting Solutions. This role is highly hands-on, perfect for an innovator who excels in dynamic, product-defining environments.As a Principal Engineer within our team, you will play a crucial role in shaping how data, AI, and workflows converge to facilitate intelligent prospecting at scale. You won't just follow a roadmap; you will help craft it, transforming ambiguous challenges such as “who should I contact next and with what message?” into robust, transparent, production-grade systems utilized by millions of sales professionals.Key ResponsibilitiesDesign signal-driven prospecting systems: Define the integration of intent signals, firmographics, behavioral insights, and CRM context to create actionable prioritization and recommendations.Hands-on, impactful developer: Write production-quality code, steer complex projects from conception to completion, and scale prototypes into full-fledged systems.AI and systems integration: Guide the integration of machine learning and generative AI models into deterministic workflows, balancing efficiency with transparency and user trust.Influential technical leadership: Shape not only the construction of the product but also its vision, collaborating closely with Product to define interfaces, workflows, and necessary trade-offs.Extensibility focus: Design systems capable of functioning across diverse accounts, buying groups, and regions while ensuring adaptability and ongoing evolution.Cross-department collaboration: Work collaboratively across CRM, data, AI, and GTM teams to synchronize patterns and avoid localized optimizations.Elevate technical standards: Foster a culture of excellence in engineering practices and innovation.
Collaboration Fuels Innovation. Join Roku, the leader in TV streaming technology.As the foremost TV streaming platform across the U.S., Canada, and Mexico, Roku is dedicated to transforming the way viewers engage with television. Our pioneering spirit in streaming technology aims to connect every television globally. We link audiences to their favorite content, empower content creators to grow and monetize their reach, and offer advertisers innovative ways to connect with consumers.From day one at Roku, your contributions will be significant and valued. In our rapidly growing public company, everyone plays an essential role. You will have the chance to enhance the experiences of millions of TV streamers while gaining invaluable insights across various fields. About Our Team At Roku, our Trust Engineering team is a passionate and cohesive group of professionals dedicated to safeguarding our customers, partners, devices, services, infrastructure, and data. We collaborate closely, sharing knowledge and expertise to remain at the forefront of security challenges. By joining us, you will become part of a vibrant team that thrives on overcoming obstacles and celebrating successes together. Role Overview As a Security Researcher Intern at Roku, you will actively participate in our mission to enhance the security and reliability of our streaming services. Collaborating with seasoned professionals, you will gain hands-on experience in security research, threat analysis, and the development of innovative security solutions.
POS-9034About Our TeamThe Commerce Hub at HubSpot is revolutionizing how businesses sell, bill, and manage revenue seamlessly within our platform. Handling billions in customer transactions, our focus on accuracy, clarity, and reliability is paramount. We are developing an AI-first commerce ecosystem that integrates flawlessly with HubSpot’s CRM, offering a streamlined, consistent, and adaptable experience for both sellers and buyers.About the RoleWe are in search of a Principal Software Engineer to drive the technical evolution of Commerce Hub. This pivotal role demands hands-on involvement, where you will engage in coding, exploring services, evaluating complex designs, troubleshooting intricate systems, and taking ownership of the architecture for critical components in CPQ, Billing, Payments, and Revenue OS.Your ResponsibilitiesDevelop a Cohesive, Scalable PlatformInfluence the technical roadmap for CPQ, Billing, and Payments using strong, decisive patterns.Define and enhance core domain models to ensure consistent and predictable behavior for pricing, products, contracts, invoices, and payments.Create frameworks that facilitate easy extensions without increasing complexity.Be a Proactive, Impactful BuilderRegularly write code, lead design reviews, and construct impactful systems from start to finish.Manage extensive multi-team projects that encompass CPQ, Billing, and Payments.Transform prototypes into scalable production-ready solutions.Guide Architectural DirectionEstablish patterns for extensibility, contract boundaries, financial accuracy, event-driven consistency, and safe interactions between AI/agents and commerce objects.Advocate for simplicity in complex domains while maintaining consistency across surfaces.Collaborate Closely with Product LeadershipShape product strategies across CPQ, Buyer Portal, and Revenue OS.Assist teams in navigating trade-offs between speed, accuracy, compliance, and long-term platform sustainability.Elevate Organizational StandardsMentor senior engineers and technical leads.Drive informed design choices and facilitate learning from incidents and significant migrations.Encourage teams to align on best practices and strategic goals.
Full-time|On-site|Cambridge, MA USA; San Francisco, CA USA
Join our innovative team at Lila Sciences as an AI Lab Research Engineer. In this role, you will contribute to cutting-edge AI research and development, focusing on enhancing the capabilities of our laboratory systems. Your expertise will help drive forward our mission to revolutionize scientific research through artificial intelligence.
Join Harvard University as a Senior Research Software Engineer, where you will play a pivotal role in advancing research through innovative software solutions. You will collaborate with researchers across various disciplines, design scalable systems, and contribute to cutting-edge projects that impact the academic community and beyond.
At Toyota Research Institute (TRI), we are dedicated to enhancing the quality of human life through innovative technology. Our mission is to develop advanced tools and capabilities that enrich the human experience. To spearhead this transformative evolution in mobility, we have assembled a premier team that is at the forefront of advancements in AI, robotics, driving technologies, and materials science.The TeamThe Future Factory team within TRI's Energy and Materials division is committed to pioneering state-of-the-art tools and methodologies that expedite change while enhancing flexibility and efficiency in Toyota's product design and manufacturing processes. Our goal is to accelerate the transition to a zero-emissions future. To accomplish this, we are constructing comprehensive AI systems that can reason about the design and manufacture of physical objects—encompassing geometry, constraints, simulation, and assembly—and creating the engineering infrastructure necessary for training, evaluating, and iterating on these systems at scale.The OpportunityWe are seeking a Senior Research Engineer to collaborate with us in developing the systems and tools that drive our research in physical AI. This role is ideal for candidates with a robust software engineering background, extensive experience in geometry or physical modeling, and a genuine passion for understanding the manufacturing process.As a research engineer on our team, you will design and construct the pipelines and tools that enable researchers to operate swiftly and assess what matters most—ranging from large-scale training and evaluation frameworks to the geometry processing and physics-aware components integral to our models. You will work at the intersection of software engineering and research, translating cutting-edge concepts into reliable, production-ready implementations.
Full-time|$220K/yr - $275K/yr|On-site|Cambridge, Massachusetts, United States, New York, New York, United States
Iterative Health is at the forefront of healthcare technology and services, dedicated to accelerating clinical research to improve patient outcomes. We manage a premier network of over 70 clinical research sites across the US and Europe, focused on expediting the market introduction of innovative gastrointestinal (GI) and hepatology therapies. Our mission is to enhance the success and growth of our partner sites by equipping them with technology-driven services. By combining extensive expertise in clinical trials with pioneering AI, we empower research teams and study sponsors to broaden and accelerate access to groundbreaking therapeutics for patients in need.About the RoleThe Chief of Staff (CoS) will collaborate closely with the CEO, acting as a trusted advisor, gatekeeper, problem solver, and strategic partner. This role is pivotal in shaping and executing strategies that align with our mission and is considered a fast-track opportunity for ascending to an Executive role within the company. You will be integral to both internal and external initiatives, providing strategic oversight to operational and communication needs throughout the organization.As CoS, you will adeptly manage complex situations and multiple responsibilities, balancing long-term projects with immediate demands. This position offers a front-row seat to the dynamism of launching a startup, presenting an excellent opportunity to leverage your comprehensive insight into the organization to identify challenges, devise solutions, and execute critical workflows. This role is perfect for high achievers who excel at the intersection of strategy and execution, enjoy tackling ambiguous problems, and seek expedited exposure to executive-level decision-making.This position resides within the Office of the CEO and will oversee the current Strategy and Operations team. You will begin onboarding with the current Chief of Staff and will report directly to our CEO once fully ramped up.
Full-time|On-site|Cambridge, MA USA; London, UK; San Francisco, CA USA
Join Lila Sciences as a Staff or Principal Engineer specializing in Technical Mitigations Research. This role offers an exciting opportunity to leverage your engineering expertise to develop innovative solutions in the field of technical mitigations.
Full-time|$224K/yr - $336K/yr|On-site|Cambridge, MA USA; San Francisco, CA USA
Your Impact at Lila As a Senior or Principal Research Engineer specializing in Synthetic Data, you will play a pivotal role in shaping the vision, roadmap, and execution of our synthetic data initiatives. Your responsibilities will span from asset generation and simulation to integrating machine learning training and achieving measurable enhancements in model performance. Collaborating closely with our Research Engineering team, you will design, generate, and implement artificial datasets aimed at training, testing, and refining Lila’s platform to achieve our strategic objectives. What You Will Build Define and refine the synthetic data strategy along with a comprehensive multi-quarter roadmap. Create evaluation frameworks that effectively connect synthetic interventions with genuine model performance. Establish high standards for asset quality, diversity, thorough documentation, and reproducibility while fostering a robust review culture. What You Will Need to Succeed Over 6 years of experience in applied ML/ML systems, with at least 3 years leading industry initiatives, showcasing a strong track record in advanced algorithms and frameworks designed for large-scale synthetic data generation. More than 8 years of experience working with contemporary ML workflows, including Python, PyTorch, dataset tools, training loops, and evaluation frameworks; adept at profiling and optimizing GPU-intensive pipelines. Bonus Points For A proven history of constructing synthetic datasets from source data to significantly enhance model performance in specific domains. Experience with instruction fine-tuning and hill-climbing techniques. Ability to translate product requirements and feedback into a scalable synthetic data generation pipeline. Knowledge of quantization, distillation, routing, mixture-of-experts, and cost optimization at scale. Experience in compliance-heavy settings (HIPAA, PCI, FedRAMP) and with on-premises/VPC deployments. About Lila Lila Sciences stands at the forefront of innovation as the world’s first scientific superintelligence platform and autonomous lab, dedicated to life sciences, chemistry, and materials science. We are ushering in an era of limitless discovery by harnessing AI to enhance every facet of the scientific method. Our mission is to empower scientists to tackle humanity's most pressing challenges in health, climate, and sustainability at an unprecedented pace and scale. Discover more about our mission at www.lila.ai. If this sounds like an environment in which you would thrive, we encourage you to apply even if your experience doesn't perfectly align with every requirement listed.
Harvard University is hiring a Principal Research Scientist in the Sciences - Chemistry and Chemical Biology department based in Cambridge. This position guides research activities and partners with faculty and other scientists to deepen knowledge in chemistry and chemical biology. Key responsibilities Lead research projects focused on chemistry and chemical biology topics Work with faculty and research teams to design experiments and analyze results Use new approaches to solve challenging scientific problems Support the creation of scientific papers and presentations
Join our dynamic team at Ramboll as a Senior / Principal Electrical Engineer. In this role, you will lead innovative projects, collaborate with a talented team, and contribute to the development of sustainable electrical solutions. Your expertise will be pivotal in driving forward our commitment to excellence in engineering.
The Center for Nanoscale Systems at Harvard University is hiring a Research and Innovation Engineer based in Cambridge. This role supports collaborative research efforts focused on nanoscale systems and their use across various scientific disciplines. Role overview As a Research and Innovation Engineer, work will involve partnering with teams from different backgrounds to move research projects forward. The position centers on nanoscale systems, contributing to studies and developments that span several areas of science. Collaboration This role requires regular interaction with interdisciplinary groups, facilitating progress and innovation in ongoing projects. The work environment values teamwork and the exchange of ideas between researchers from diverse fields.
Full-time|$167.2K/yr - $209K/yr|On-site|Cambridge, MA
Join Cambridge Mobile Telematics (CMT), the world's leading telematics service provider, dedicated to enhancing road safety and improving driver behavior. Our cutting-edge AI platform, DriveWell Fusion®, integrates sensor data from millions of IoT devices—including smartphones, proprietary Tags, connected vehicles, dashcams, and third-party devices—melding it with contextual information to deliver a comprehensive analysis of vehicle and driver interactions. Our insights empower auto insurers, automotive manufacturers, mobility companies, and public sector organizations to optimize risk assessment, safety protocols, claims processing, and driver improvement initiatives. Based in Cambridge, MA, with global offices in Budapest, Chennai, Seattle, Tokyo, and Zagreb, CMT actively monitors and safeguards millions of drivers worldwide every day.As a Principal Software Engineer within our Trip Processing team, you will play a crucial role in delivering innovative technical solutions at the core of our advanced telematics pipeline. Collaborating closely with product and research teams, you will design, develop, and implement new features while mentoring junior engineers and enhancing our codebase. Your contributions will be vital in upholding our high standards of software quality to meet the expectations of our insurance partners.We seek a collaborative, customer-focused, and imaginative Principal Software Engineer II - Backend who is eager to help make roads safer and drivers more responsible!
Join Harvard University as a Research Infrastructure and Software Engineer, where you will play a pivotal role in enhancing research capabilities through innovative software solutions. Collaborate with cross-functional teams to design, implement, and maintain robust infrastructure that supports diverse research initiatives. Your expertise will enable researchers to focus on their work while you ensure seamless access to data and resources.
POS-4092 Team and Product Focus The Data Hub team at HubSpot connects scattered data sources to deliver practical insights for Revenue Operations, marketing, sales, and customer teams. By integrating information from various channels and tools, the team improves data quality and makes this data actionable within HubSpot. This enables teams to run AI-powered demand generation, optimize campaigns, and produce reliable reports, without requiring deep expertise in data systems. Product engineering here blends data engineering, machine learning, applied AI, and market strategy. The group prioritizes reliability, cost efficiency, and scalability, while always considering usability for marketers and sales professionals. Role Overview HubSpot is seeking a Lead Principal Software Engineer to steer the next phase of Data Hub's development. This platform is evolving into the central engine for data-driven demand generation company-wide. Key Responsibilities Take ownership of critical components in the data lake and analytics architecture, working with technologies such as Iceberg, Spark, and both batch and streaming data pipelines. These systems underpin large-scale demand generation, segmentation, and scoring. Design and refine data systems to achieve the right balance between cost, latency, data freshness, and reliability. Apply principles like the CAP theorem, efficient partitioning, and thoughtful storage layout to guide decisions. Collaborate closely with Product Management, product analytics, and go-to-market leaders to deliver solutions that drive business outcomes: improved lead scoring, enhanced funnel visibility, audience segmentation, and campaign attribution for marketing and sales. Contribute to transforming Data Hub into an AI-powered platform, aiming for curated, always-available datasets that support AI agents and reporting tools, eliminating the need for manual integrations or custom pipelines. This is a hands-on principal engineering position. The role involves building systems, working alongside product and design, and amplifying the impact of HubSpot's broader engineering community.
Full-time|$171K/yr - $230.5K/yr|On-site|Cambridge, MA USA
Role Overview Lila Sciences is seeking a Principal Engineer with expertise in AI Security for its Cambridge, MA office. This senior individual contributor will help define and drive the technical strategy to secure AI applications across the organization. The role involves close collaboration with IT and business teams to ensure AI tools and platforms are implemented safely and in compliance with internal and external requirements. Securing both third-party and in-house AI tools is central to this position. The work will focus on protecting sensitive data, intellectual property, and scientific processes as AI becomes increasingly embedded in Lila's operations. What You Will Do Enterprise AI Security Strategy: Develop and roll out security controls and guidelines for using AI tools throughout the company, covering LLM APIs and SaaS AI platforms. AI Gateway & Agentic Gateway Security: Design and enforce controls for AI gateways, monitoring and managing access to AI systems. Ensure agentic workflows are secured with strong identity and authorization measures. AI Red Teaming & Adversarial Testing: Lead red teaming and adversarial testing efforts to uncover vulnerabilities in AI usage, such as prompt injection and data exfiltration risks. Data Protection for AI Usage: Establish and maintain safeguards to prevent sensitive data exposure through AI systems, with a focus on input/output filtering and secure data management. Multi-Layer AI Security: Integrate AI security practices with the organization's broader security framework, maintaining visibility and control over AI service access and data flows. AI Threat Modeling: Build and maintain threat models tailored to enterprise AI applications, addressing risks like data leaks and unauthorized agent actions. Vendor & Platform Security: Assess and advise on secure integration of third-party AI vendors, with close attention to their data handling practices and model behavior.
Full-time|$163.4K/yr - $228K/yr|On-site|Cambridge, MA USA
Your Impact at Lila Sciences Lila Sciences is on the lookout for a highly skilled Staff/Principal Mechanical Engineer to enhance our Hardware & Controls Engineering team. The specific title—Staff or Principal—will align with your level of experience and expertise. As a pivotal technical leader, you will apply your extensive knowledge to design and develop components for workcell robotics, mechanical systems, and automation within the realms of life sciences and physical sciences. You'll collaborate with a diverse team of experimental scientists, AI/ML specialists, software engineers, and process automation experts to spearhead intricate projects, mentor multidisciplinary teams, and deliver cutting-edge automation solutions. What You Will Be Creating Oversee the design and execution of bench-scale robotics and mechanical systems for advanced automation in life science and physical science applications. Craft innovative pneumatic, electro-mechanical, and optical solutions tailored for state-of-the-art robotic workcells utilized in biological research and materials discovery. Lead and mentor teams in advanced CAD design and analyses using SolidWorks, optimizing systems for high-throughput workflows. Manage the creation and validation of designs through rapid prototyping techniques such as 3D printing and laser cutting. Facilitate cross-functional collaborations to seamlessly integrate mechanical designs with software and controls across scientific fields. Devise strategies to convert manual processes into automated workflows while adhering to stringent safety and quality standards. Coordinate with external suppliers for bespoke component development and system integration. What You Need to Succeed A Bachelor's or Master's degree in Mechanical Engineering, Robotics, or a related discipline. 8+ years of mechanical engineering experience, showcasing proven expertise in life science and physical science automation (title will be aligned with experience & expertise). Extensive proficiency in SolidWorks CAD design, GD&T, and DFMA methodologies. In-depth experience utilizing requirement management systems, product lifecycle management, and product data management systems. Proven leadership in managing complex projects and mentoring engineering teams. Bonus Points For Significant experience in automation across scientific disciplines, with a strong command of SolidWorks CAD design, PDM, and related technologies.
Full-time|$163.4K/yr - $228K/yr|On-site|Cambridge, MA USA
Your Impact at Lila Lila Sciences is on the lookout for a talented Industrial Engineer to take the lead in designing and optimizing the physical layout of our cutting-edge AI Science Factories. In this pivotal role, you will integrate laboratory instrumentation and robotics into a seamless and efficient factory design. Your collaboration with hardware engineering, scientific teams, robotics, facilities, and operations will be crucial in creating layouts that prioritize safety, scalability, and high-throughput autonomous research. This position is vital for translating intricate cross-functional requirements into a factory environment that propels Lila’s next-generation scientific capabilities. What You'll Be Building Take ownership of the complete factory layout, focusing on spatial planning, adjacency mapping, and utility requirements. Integrate diverse lab instrumentation layouts from various scientific and engineering domains into a cohesive, high-performance factory design. Work closely with teams in hardware, robotics, science, automation, safety, and facilities to incorporate essential requirements for utilities, safety, accessibility, maintenance, and environmental controls. Create and maintain precise 2D and 3D CAD models of the entire factory layout, managing version control and change updates effectively. Collaborate with robotic teams to conduct simulations and scenario analyses, evaluating throughput, operational efficiency, and identifying bottlenecks. Partner with construction, facilities, and external vendors to ensure that physical buildouts accurately reflect intended designs and are scalable to meet future demands. Develop standards, documentation, and layout guidelines for new lab instrumentation and factory expansions. What You’ll Need to Succeed Bachelor’s or Master’s degree in Industrial Engineering, Mechanical Engineering, Manufacturing Engineering, Systems Engineering, or a related field. Proven experience in designing factory, laboratory, or production layouts in complex environments. Expertise in CAD tools (e.g., AutoCAD, REVIT, SolidWorks). Strong knowledge of workflow optimization, material flow, ergonomics, and spatial systems. Ability to work collaboratively across multidisciplinary engineering and scientific teams. Exceptional communication and documentation skills.
Join Riverlane as a Staff Testing Engineer in Cambridge, UK. This is a full-time, permanent position offering a hybrid working model.Salary: £95,000 to £120,000, depending on experience, plus bonus and benefits.We offer a competitive salary range based on the candidate's experience, industry knowledge, and relevant skills. Every offer will be tailored to reflect the applicant's background and accomplishments.Part-time applications are welcome. Please indicate your preferred working schedule in your cover letter.About RiverlaneAt Riverlane, we are on a mission to revolutionize quantum error correction (QEC) to facilitate a new era of technological advancement. Our work spans various fields, including material and climate science and drug design simulations, showcasing the potential of quantum computing in addressing humanity's grand challenges. As the leading organization in QEC technology, we are committed to overcoming the industry's most significant technical challenges.With over $125M in funding, we are accelerating our pioneering research and development in QEC and collaborating with top quantum hardware companies and government entities to make fault-tolerant quantum computing a reality.
Location: Cambridge, UK | Employment Type: Full-time | Contract Type: Permanent | Work Arrangement: HybridSalary Range: £90,000 to £115,000 depending on experience + Bonus + BenefitsWe are open to considering part-time applications for this role. Please specify your preferred working hours in your cover letter.About UsAt Riverlane, we are on a mission to master quantum error correction (QEC), paving the way for breakthroughs in material science, climate science, and drug design. Quantum computers are set to tackle some of humanity's most pressing challenges, and we are proud to lead the industry in QEC technology. Our team thrives on a blend of expertise, innovation, and passion, which are essential to overcoming this complex problem. With over $125M in funding, we collaborate with top global quantum hardware providers and government agencies to make fault-tolerant quantum computing a reality.
POS-31591About Our TeamThe Prospecting Solutions team is revolutionizing the way B2B SMB and mid-market sales teams cultivate their pipeline. The current outbound sales approach is often inefficient and outdated, with representatives dedicating excessive time to research, tool integration, and uncertain contact strategies. Our focus transcends mere outreach execution; we prioritize intelligent sourcing, prioritization, and trust.This team is developing a comprehensive, signal-driven prospecting ecosystem that aligns with contemporary B2B purchasing behavior: account-centered, aware of buying groups, and trust-oriented. Our mission is to merge human discernment with automation, enabling sales teams to generate consistent, high-quality pipeline without compromising their brand integrity or their representatives' well-being.About the RoleWe are seeking a Principal Software Engineer to serve as a pivotal technical leader for Prospecting Solutions. This role is highly hands-on, perfect for an innovator who excels in dynamic, product-defining environments.As a Principal Engineer within our team, you will play a crucial role in shaping how data, AI, and workflows converge to facilitate intelligent prospecting at scale. You won't just follow a roadmap; you will help craft it, transforming ambiguous challenges such as “who should I contact next and with what message?” into robust, transparent, production-grade systems utilized by millions of sales professionals.Key ResponsibilitiesDesign signal-driven prospecting systems: Define the integration of intent signals, firmographics, behavioral insights, and CRM context to create actionable prioritization and recommendations.Hands-on, impactful developer: Write production-quality code, steer complex projects from conception to completion, and scale prototypes into full-fledged systems.AI and systems integration: Guide the integration of machine learning and generative AI models into deterministic workflows, balancing efficiency with transparency and user trust.Influential technical leadership: Shape not only the construction of the product but also its vision, collaborating closely with Product to define interfaces, workflows, and necessary trade-offs.Extensibility focus: Design systems capable of functioning across diverse accounts, buying groups, and regions while ensuring adaptability and ongoing evolution.Cross-department collaboration: Work collaboratively across CRM, data, AI, and GTM teams to synchronize patterns and avoid localized optimizations.Elevate technical standards: Foster a culture of excellence in engineering practices and innovation.
Collaboration Fuels Innovation. Join Roku, the leader in TV streaming technology.As the foremost TV streaming platform across the U.S., Canada, and Mexico, Roku is dedicated to transforming the way viewers engage with television. Our pioneering spirit in streaming technology aims to connect every television globally. We link audiences to their favorite content, empower content creators to grow and monetize their reach, and offer advertisers innovative ways to connect with consumers.From day one at Roku, your contributions will be significant and valued. In our rapidly growing public company, everyone plays an essential role. You will have the chance to enhance the experiences of millions of TV streamers while gaining invaluable insights across various fields. About Our Team At Roku, our Trust Engineering team is a passionate and cohesive group of professionals dedicated to safeguarding our customers, partners, devices, services, infrastructure, and data. We collaborate closely, sharing knowledge and expertise to remain at the forefront of security challenges. By joining us, you will become part of a vibrant team that thrives on overcoming obstacles and celebrating successes together. Role Overview As a Security Researcher Intern at Roku, you will actively participate in our mission to enhance the security and reliability of our streaming services. Collaborating with seasoned professionals, you will gain hands-on experience in security research, threat analysis, and the development of innovative security solutions.
POS-9034About Our TeamThe Commerce Hub at HubSpot is revolutionizing how businesses sell, bill, and manage revenue seamlessly within our platform. Handling billions in customer transactions, our focus on accuracy, clarity, and reliability is paramount. We are developing an AI-first commerce ecosystem that integrates flawlessly with HubSpot’s CRM, offering a streamlined, consistent, and adaptable experience for both sellers and buyers.About the RoleWe are in search of a Principal Software Engineer to drive the technical evolution of Commerce Hub. This pivotal role demands hands-on involvement, where you will engage in coding, exploring services, evaluating complex designs, troubleshooting intricate systems, and taking ownership of the architecture for critical components in CPQ, Billing, Payments, and Revenue OS.Your ResponsibilitiesDevelop a Cohesive, Scalable PlatformInfluence the technical roadmap for CPQ, Billing, and Payments using strong, decisive patterns.Define and enhance core domain models to ensure consistent and predictable behavior for pricing, products, contracts, invoices, and payments.Create frameworks that facilitate easy extensions without increasing complexity.Be a Proactive, Impactful BuilderRegularly write code, lead design reviews, and construct impactful systems from start to finish.Manage extensive multi-team projects that encompass CPQ, Billing, and Payments.Transform prototypes into scalable production-ready solutions.Guide Architectural DirectionEstablish patterns for extensibility, contract boundaries, financial accuracy, event-driven consistency, and safe interactions between AI/agents and commerce objects.Advocate for simplicity in complex domains while maintaining consistency across surfaces.Collaborate Closely with Product LeadershipShape product strategies across CPQ, Buyer Portal, and Revenue OS.Assist teams in navigating trade-offs between speed, accuracy, compliance, and long-term platform sustainability.Elevate Organizational StandardsMentor senior engineers and technical leads.Drive informed design choices and facilitate learning from incidents and significant migrations.Encourage teams to align on best practices and strategic goals.
Full-time|On-site|Cambridge, MA USA; San Francisco, CA USA
Join our innovative team at Lila Sciences as an AI Lab Research Engineer. In this role, you will contribute to cutting-edge AI research and development, focusing on enhancing the capabilities of our laboratory systems. Your expertise will help drive forward our mission to revolutionize scientific research through artificial intelligence.
Join Harvard University as a Senior Research Software Engineer, where you will play a pivotal role in advancing research through innovative software solutions. You will collaborate with researchers across various disciplines, design scalable systems, and contribute to cutting-edge projects that impact the academic community and beyond.
At Toyota Research Institute (TRI), we are dedicated to enhancing the quality of human life through innovative technology. Our mission is to develop advanced tools and capabilities that enrich the human experience. To spearhead this transformative evolution in mobility, we have assembled a premier team that is at the forefront of advancements in AI, robotics, driving technologies, and materials science.The TeamThe Future Factory team within TRI's Energy and Materials division is committed to pioneering state-of-the-art tools and methodologies that expedite change while enhancing flexibility and efficiency in Toyota's product design and manufacturing processes. Our goal is to accelerate the transition to a zero-emissions future. To accomplish this, we are constructing comprehensive AI systems that can reason about the design and manufacture of physical objects—encompassing geometry, constraints, simulation, and assembly—and creating the engineering infrastructure necessary for training, evaluating, and iterating on these systems at scale.The OpportunityWe are seeking a Senior Research Engineer to collaborate with us in developing the systems and tools that drive our research in physical AI. This role is ideal for candidates with a robust software engineering background, extensive experience in geometry or physical modeling, and a genuine passion for understanding the manufacturing process.As a research engineer on our team, you will design and construct the pipelines and tools that enable researchers to operate swiftly and assess what matters most—ranging from large-scale training and evaluation frameworks to the geometry processing and physics-aware components integral to our models. You will work at the intersection of software engineering and research, translating cutting-edge concepts into reliable, production-ready implementations.
Full-time|$220K/yr - $275K/yr|On-site|Cambridge, Massachusetts, United States, New York, New York, United States
Iterative Health is at the forefront of healthcare technology and services, dedicated to accelerating clinical research to improve patient outcomes. We manage a premier network of over 70 clinical research sites across the US and Europe, focused on expediting the market introduction of innovative gastrointestinal (GI) and hepatology therapies. Our mission is to enhance the success and growth of our partner sites by equipping them with technology-driven services. By combining extensive expertise in clinical trials with pioneering AI, we empower research teams and study sponsors to broaden and accelerate access to groundbreaking therapeutics for patients in need.About the RoleThe Chief of Staff (CoS) will collaborate closely with the CEO, acting as a trusted advisor, gatekeeper, problem solver, and strategic partner. This role is pivotal in shaping and executing strategies that align with our mission and is considered a fast-track opportunity for ascending to an Executive role within the company. You will be integral to both internal and external initiatives, providing strategic oversight to operational and communication needs throughout the organization.As CoS, you will adeptly manage complex situations and multiple responsibilities, balancing long-term projects with immediate demands. This position offers a front-row seat to the dynamism of launching a startup, presenting an excellent opportunity to leverage your comprehensive insight into the organization to identify challenges, devise solutions, and execute critical workflows. This role is perfect for high achievers who excel at the intersection of strategy and execution, enjoy tackling ambiguous problems, and seek expedited exposure to executive-level decision-making.This position resides within the Office of the CEO and will oversee the current Strategy and Operations team. You will begin onboarding with the current Chief of Staff and will report directly to our CEO once fully ramped up.
Mar 17, 2026
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