Senior Scientist I, Pipeline Development & Targeted Delivery

We are seeking a highly motivated and experienced Senior Scientist I to join our Pipeline Development & Targeted Delivery team at AbbVie. In this pivotal role, you will lead innovative research efforts aimed at advancing our therapeutics pipeline. You will collaborate with cross-functional teams to design experiments, analyze data, and contribute to strategic decision-making processes.

Your Contribution at Lila Sciences Lila Sciences is actively seeking a dedicated (Senior) Research Associate to become an integral part of our dynamic Life Sciences team. This pivotal role will be centered around the formulation of lipid nanoparticles (LNPs), their functionalization with targeting ligands, and the characterization of the resulting targeted LNPs (tLNPs). The ideal candidate will possess substantial hands-on experience in LNP formulation and characterization, bioconjugation, protein characterization, and automation technologies. Your expertise will significantly enhance our understanding of the delivery space, enabling a high-throughput closed-loop screening cascade for tLNPs. You will work collaboratively with professionals across protein, cell biology, automation, chemistry, machine learning, and data science teams to establish advanced tools for targeted nucleic acid delivery. Your Key Responsibilities Design, execute, and characterize LNP formulations utilizing various scales and mixing modalities (e.g., DLS, ribogreen, TNS). Develop and optimize high-throughput ligand conjugation and purification methodologies, leveraging automation and robotics to maximize throughput. Collaborate with cell assay and antibody experts to screen candidates across diverse tissue targets in in vivo models. Engage with chemists, biologists, engineers, and data scientists to document processes, share insights, and refine best practices in autonomous flow chemistry. Create, implement, and uphold Standard Operating Procedures (SOPs) for both existing and emerging lab processes. Your Qualifications for Success MSc in Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences, or a closely related field with 3+ years of hands-on experience in targeted LNP production or a BSc with 5+ years of relevant experience. Industry experience is highly desirable. Strong proficiency in bioanalytical techniques (e.g., DLS, fluorescence spectroscopy, electrophoresis, in vitro assays). Experience in protein and antibody design and characterization. Familiarity with automation and high-throughput workflows is preferred. Exceptional troubleshooting, communication, and collaboration skills, with a proven ability to work effectively across interdisciplinary teams. About Lila Sciences Lila Sciences is at the forefront of innovation as the world's first scientific superintelligence platform and autonomous laboratory focused on life sciences, chemistry, and materials science. We are pioneering a new era of limitless discovery by harnessing AI capabilities to enhance every facet of the scientific method. Our mission is to leverage scientific superintelligence to address humanity's most pressing challenges.

We are seeking a passionate and detail-oriented Scientist I to join our innovative team at Integrated Resources Inc. This entry-level position offers a fantastic opportunity to contribute to groundbreaking research and development projects. You will work closely with experienced scientists to support various laboratory activities, including experimental design, data collection, and analysis.

We are seeking a motivated and detail-oriented Scientist I to join our dynamic team in Cambridge. The ideal candidate will have a strong background in scientific research, with a passion for innovation and problem-solving. This entry-level role offers an exciting opportunity to contribute to groundbreaking projects and advance your career in a collaborative environment.

Your Impact at Lila In this pivotal role, you will spearhead the innovation and validation of advanced pooled assays utilizing mammalian cells. Your work will encompass everything from proof of concept to automated screening processes, enabling the generation of intricate, high-dimensional datasets. This position involves collaboration across cell biology, protein design, and nucleic acid teams to facilitate biologic development programs, focusing on the rapid assessment of binding, stability, function, and immunogenicity of diverse biologics. What You'll Be Building Create next-generation mammalian display-based assays for binding, stability, function, and immunogenicity. Implement cutting-edge multiomic, single-cell, and in situ sequencing workflows to design innovative, highly multiplexed assays. Collaborate with protein design, nucleic acid, and automation teams to leverage these workflows in biologics development. Closed-Loop Experimentation and Execution: Work closely with engineering and automation teams to architect automated, high-throughput experimentation platforms that yield data-rich workflows. Join forces with the AI team to conduct iterative experiments in real time, facilitating rapid optimization and discovery cycles. Collaborate, Lead & Communicate: Engage with cell biologists, synthetic biologists, automation engineers, protein design scientists, and data scientists to document systems, share insights, and refine best practices in autonomous science. Mentor junior scientists, align project milestones with internal and external collaborators, contribute to intellectual property and publications, and present findings across the organization. What You’ll Need to Succeed Ph.D. in Chemical/Biomedical Engineering, Biochemistry, Pharmaceutical Sciences, Immunology, or a related discipline (or M.S./B.S. with 5–8+ years of relevant industry experience). Proficiency in the development and/or application of mammalian display or similar pooled mammalian systems (perturb-seq, MPRA, etc.). Experience in designing, executing, and analyzing single-cell, in situ, or multiomic sequencing experiments. Expertise in creating complex libraries of defined sequences in mammalian cells. Experience in designing, executing, and analyzing flow cytometry and sorting experiments. Familiarity with next-generation sequencing (NGS) based experimental design and analysis.

Role overview Lila Sciences seeks a Scientist I/II in Drug Delivery Chemistry for its Cambridge, MA location. This role centers on advancing drug delivery systems that align with the company’s broader research objectives. Key responsibilities Collaborate with fellow researchers to design and refine drug delivery technologies. Apply chemistry expertise to enhance scientific strategies and laboratory processes. Contribute to projects focused on improving patient outcomes through innovative drug delivery solutions. Location This position is based in Cambridge, Massachusetts.

Join AbbVie, a global biopharmaceutical company, as a Senior Scientist I in our Neuroscience division specializing in Biologics Screening. In this role, you will lead innovative research efforts to develop therapies that address unmet medical needs in the field of neuroscience.

Join AbbVie as a Senior Scientist I in the field of siRNA in vitro biology. In this role, you will leverage your extensive knowledge and skills in molecular biology to contribute to innovative research and development projects. Collaborate with a team of dedicated scientists to explore new therapeutic avenues and advance our understanding of RNA interference.

Join AbbVie as a Senior Scientist II in our Assay Development team, focusing on innovative research in Discovery Psychiatry. This role involves designing, developing, and optimizing assays to advance our understanding of psychiatric disorders. You will collaborate with cross-functional teams to drive research initiatives and contribute to the discovery of effective treatments.The ideal candidate will possess strong scientific expertise, a passion for psychiatric research, and the ability to thrive in a dynamic environment.

Join our innovative team as a Senior Scientist where you'll drive critical research projects and make a significant impact in the field. We are seeking a highly motivated individual with a passion for scientific discovery and a strong background in relevant disciplines.

Join Integrated Resources Inc. as an Associate Scientist I, where you will contribute to innovative scientific research and development projects. As a pivotal part of our team, your role will involve conducting experiments, analyzing data, and collaborating with multidisciplinary teams to advance our scientific objectives.

We are seeking a highly motivated and detail-oriented Associate Scientist I to join our dynamic team in Cambridge. The ideal candidate will assist in the design and execution of experiments, analysis of data, and contribute to various projects within our research initiatives.

COMPANY DESCRIPTION Flagship Pioneering is a leading bioplatform innovation firm dedicated to inventing and building transformative companies that aim to make a significant impact on the world. By merging top-tier scientific talent with entrepreneurial visionaries, we mobilize the resources necessary to support bold innovations. Our endeavors in human health, sustainability, and beyond accelerate scientific advancements across a spectrum of fields, including disease detection and treatment, nature-positive agriculture, and cutting-edge AI applications. What distinguishes Flagship is our unique capacity to propel science and technology forward by integrating innovation, company formation, and capital investment under one roof—an approach that is largely unprecedented. Our scientific pioneers, entrepreneurial leaders, and expert capital managers are aligned in a structured process that facilitates transformative innovation for the benefit of both humanity and the planet. We have founded companies that tackle some of society's most pressing challenges, including delivering vaccines to billions during the COVID-19 pandemic, finding cures for chronic diseases, enhancing health outcomes, and fostering sustainable agricultural practices. Flagship Pioneering has been recognized twice on FORTUNE’s “Change the World” list, acknowledging our positive social and environmental contributions, and we have also been honored on Fast Company’s annual list of the World’s Most Innovative Companies. THE ROLE We are on the lookout for a Senior Scientist to spearhead the design, characterization, and optimization of aerosolizable particle systems. This pivotal role involves developing a comprehensive understanding of engineered particles during their generation, dispersion, and transport in air, and translating that knowledge into robust and scalable material and system designs. The Senior Scientist will operate at the intersection of materials science, aerosol physics, and experimental engineering. You will lead the development of aerosol testing capabilities, shape experimental strategies, and connect particle design with airborne performance. This individual will play a vital role in establishing core methodologies and driving projects from concept to validation. In this highly collaborative position, you will work closely with formulation, process development, and hardware teams to ensure seamless integration between particle design, production processes, and real-world deployment challenges.

AbbVie is seeking a talented and motivated Associate Scientist II or Scientist I to join our dynamic In Vivo Pharmacology team in Cambridge. As part of our innovative research environment, you will play a crucial role in advancing our understanding of pharmacological mechanisms through in vivo studies. This position offers an exciting opportunity to contribute to groundbreaking research that has the potential to transform patient care.

COMPANY DESCRIPTION Flagship Pioneering is a groundbreaking bioplatform innovation organization dedicated to inventing and building transformative companies that make a positive impact on the world. We unite exceptional scientific talent with entrepreneurial visionaries and mobilize substantial capital to enable bold advancements in human health, sustainability, and beyond. Our innovative efforts span critical areas such as disease detection and treatment, nature-positive agriculture, and pioneering applications of AI that catalyze the development of new technologies. What distinguishes Flagship is our unique ability to propel science and technology forward by integrating innovation, company creation, and capital investment within a cohesive framework that is largely unprecedented. Our scientific founders, entrepreneurial leaders, and professional capital managers share a commitment to an institutionalized process that empowers us to innovate and transform for the betterment of humanity and the planet. Many of our founded companies have tackled some of the most pressing challenges facing humanity: from vaccinating billions against COVID-19 to curing complex diseases, enhancing human health, preempting illness, and bolstering global food security through improved agricultural resilience and sustainability. Flagship has earned recognition on FORTUNE’s “Change the World” list, celebrating companies that have made a significant social and environmental impact through their core business strategies, and has been named twice to Fast Company’s annual list of the World’s Most Innovative Companies. THE ROLE We are on the lookout for a Senior Scientist I or II to spearhead microbial strain engineering initiatives that will support a pioneering biological platform within one of our stealth mode startups. This position will concentrate on the design, construction, and optimization of engineered microbial strains aimed at enabling scalable production systems. The ideal candidate will manage strain development cycles from genetic design to experimental validation, collaborating closely with our discovery and bioprocess development teams to translate initial biological insights into robust strains suitable for fermentation environments. This role will also provide technical leadership within our technical operations function and aid in establishing best practices for microbial engineering in a dynamic and collaborative R&D setting.

Company Overview Flagship Labs 110 Inc. (FL110) is an innovative, privately held technology company at the forefront of developing a fully integrated, end-to-end platform that revolutionizes proteomics. Our cutting-edge platform combines advanced bioengineering, machine learning, and bespoke microelectronics to deliver unparalleled precision and insights. Backed by Flagship Pioneering, we possess the vision, courage, and resources to achieve extraordinary results. Our culture fosters collaboration and creativity, making it essential for team members to embrace diverse perspectives and an inclusive mindset. If you are excited by the prospect of working in such an environment and possess some of the qualifications listed below, we encourage you to apply. Position Overview: We are looking for a passionate and skilled (Senior) Scientist, Nanopore to become part of our dynamic team. The level for this position is flexible based on experience. Your primary focus will be on the advancement of nanopore sensing technologies, contributing to the development of a nanopore-based protein reading system. As a key member of a cross-functional team, you will collaborate closely with chemists, bioinformaticians, software developers, and hardware engineers. The ideal candidate will have a robust background in nanopore technology, particularly in protein translocation, along with either relevant experience in the biotechnology sector or a proven record of scientific accomplishment.

Role Overview AbbVie is hiring a Scientist I to join the Immunology Discovery group in Cambridge. This is an entry-level role focused on research that supports new therapies in immunology. The team values creative problem-solvers who want to help drive scientific progress. What You Will Do Collaborate with scientists on research projects in immunology Apply modern laboratory techniques to investigate immune system pathways Contribute data and insights to support the development of new therapies Work as part of a team committed to advancing scientific understanding Location This position is based in Cambridge.

Join Eurofins Scientific, a global leader in bioanalytical testing, as a Scientist specializing in Biocatalysis and Enzymatic Process Development. In this pivotal role, you will spearhead innovative research projects focusing on the development and optimization of enzymatic processes, contributing to our commitment to excellence in the field of biotechnology.

Alkeus Pharmaceuticals, Inc. is a pioneering clinical-stage biotechnology firm headquartered in Cambridge, Massachusetts, dedicated to the advancement of groundbreaking therapies aimed at addressing critical ocular diseases with significant unmet medical needs. Established in 2010, Alkeus has been diligently developing its flagship compound, gildeuretinol acetate (ALK-001), which has received designation as a breakthrough therapy and orphan drug status from the U.S. Food and Drug Administration. Gildeuretinol is currently being assessed across various clinical trials for the treatment of Stargardt disease and geographic atrophy (GA) resulting from age-related macular degeneration (AMD), a leading cause of blindness in the United States.Position Summary:The Senior Clinical Scientist will take charge of providing scientific leadership and oversight for late-stage (Phase 3) clinical development programs focused on rare diseases in the field of ophthalmology. This role is crucial to maintaining scientific integrity, ensuring regulatory compliance, and successfully executing pivotal clinical trials necessary for global registration.As a key individual contributor, the Senior Clinical Scientist will act as a primary scientific collaborator throughout the clinical development process, closely partnering with clinical operations, biostatistics, regulatory affairs, and safety teams to translate strategic objectives into high-quality Phase 3 studies. This position is ideally suited for a seasoned professional with a proven track record in late-stage clinical development, particularly in rare diseases and/or ophthalmology.

Join us as a Senior Scientist in Computational Biology at Flagship Pioneering, Inc. In this pivotal role, you will leverage your expertise to drive innovative research and development in computational biology, contributing to groundbreaking discoveries and advancements in the field.