Senior Medical Director

The Opportunity: Join Relay Therapeutics as a Senior Medical Director, where you will be pivotal in propelling our clinical pipeline from IND to proof of concept and ultimately to registration. In this role, you will partner with senior medical staff to shape clinical strategies, design clinical trials, and ensure successful execution. Collaborating across various functions including clinical project management, regulatory affairs, clinical operations, biostatistics, data management, and medical writing, you will significantly contribute as Relay Therapeutics continues to advance product candidates into clinical settings. You will provide clinical leadership to R&D teams and closely collaborate with Development leadership. We are open to remote employees

Amylyx Pharmaceuticals is on a daring mission to transform the landscape of treatments for diseases with significant unmet needs. We embrace challenges as opportunities, driving forward with urgency, rigorous scientific approaches, and a steadfast commitment to the communities we serve. As a clinical-stage organization, we are currently dedicated to addressing post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).Our mission is fueled by our exceptional team. We uphold core values of audacity, curiosity, authenticity, engagement, and accountability, fostering a culture of compassion. At Amylyx, we have assembled a skilled team eager to take decisive action, as the communities we serve cannot afford to wait. If you share our passion and are resolute in tackling some of medicine's most challenging problems, we invite you to explore the opportunity below and apply.The OpportunityAmylyx is seeking a Senior Medical Director, Clinical Development to deliver strategic and scientific leadership for one or more late-stage, pivotal programs with the possibility of expanding into additional indications and/or programs within the same molecule or across our portfolio. This role is pivotal in shaping the overall clinical development strategy and may oversee multiple programs or key components of a broader development portfolio.Reporting directly to the Senior VP of Clinical Development, you will be tasked with leading the design, execution, and analysis of clinical studies and managing the development and implementation of Clinical Development Plans across assigned assets. Your strategic input will be crucial in study design, endpoints, and regulatory strategies, ensuring alignment with overall program and corporate objectives.The ideal candidate will work collaboratively with cross-functional teams in a matrix environment, influencing stakeholders across Research, Regulatory Affairs, Clinical Operations, and Commercial to ensure that clinical and scientific considerations are fully integrated into development plans. You will proactively identify and mitigate risks, guide decision-making through data-driven insights, and uphold the highest standards of scientific rigor and data integrity.In this capacity, you will also act as a key external representative, engaging with global medical experts, investigators, regulatory authorities, and alliance partners. You may lead or mentor a team of clinical scientists and physicians and contribute to broader organizational and portfolio-level initiatives.

Scholar Rock is a pioneering biopharmaceutical company dedicated to the discovery, development, and delivery of transformative therapies for patients suffering from serious diseases with significant unmet medical needs. As a global frontrunner in the understanding of the transforming growth factor beta (TGFβ) superfamily of cell proteins, Scholar Rock is aptly named for the visual resemblance of a scholar rock to protein structures. The company is currently in the clinical stage, focusing on advancing groundbreaking treatments that leverage protein growth factors to create better health outcomes. Over the past decade, Scholar Rock has cultivated a robust pipeline aimed at improving the standard of care for conditions such as neuromuscular diseases, cardiometabolic disorders, cancer, and other areas where growth factor-targeted therapies could effectuate significant change. Scholar Rock stands out as the sole company to demonstrate clinical proof of concept for a muscle-targeted treatment for spinal muscular atrophy (SMA). We are committed to pioneering fundamentally different therapeutic approaches, supported by our proprietary platform that has developed novel monoclonal antibodies capable of exquisitely modulating protein growth factors. By utilizing cutting-edge scientific advancements in disease areas that have been historically underserved by conventional therapies, Scholar Rock is dedicated to unlocking new possibilities for patients. To learn more about our innovative approach, visit ScholarRock.com and follow us on @ScholarRock and LinkedIn.Position Overview:The Medical Director/Senior Director will report directly to the Senior Vice President of Clinical Research and will play a crucial role within the late-stage development team. This individual will be responsible for overseeing the clinical development activities for product candidates, guiding them from Proof-of-Concept through to marketing approval and ongoing lifecycle management. The ideal candidate will provide medical leadership for the clinical development of apitegromab and other late-stage product candidates in accordance with the overall corporate strategy. This role requires an enthusiastic physician-scientist with substantial hands-on experience in advancing late-stage product candidates to deliver revolutionary therapies.

Join Alkeus Pharmaceuticals, a pioneering biopharmaceutical company dedicated to transforming the lives of patients with rare diseases. We are seeking a dynamic and visionary Medical Director to lead our clinical development activities, providing strategic direction and oversight for our innovative programs.As the Medical Director, you will collaborate with cross-functional teams, engage with key opinion leaders, and contribute to the development of cutting-edge therapies. This is an exceptional opportunity for a dedicated professional looking to make a significant impact in the field of rare diseases.

About BlueRock TherapeuticsBlueRock Therapeutics LP is a pioneering clinical-stage company focused on innovative cell therapies aimed at addressing neurological and ophthalmic disorders. Our leading investigational therapies, bemdaneprocel (BRT-DA01) for Parkinson’s disease and OpCT-001 for primary photoreceptor diseases, are at the forefront of clinical development. Established in 2016 as a collaboration between Versant Ventures and Leaps by Bayer, BlueRock embodies a culture defined by resilience, urgency in transforming healthcare, integrity in our mission, and a sense of community that emphasizes our collective purpose.Our VisionWe are harnessing advanced scientific techniques to guide the differentiation of universal pluripotent stem cells into authentic, functional cells, paving the way for allogeneic cellular therapies that can tackle a wide range of diseases. Our commitment to cellular and gene therapy is shaping the future of medicine and providing hope through new therapeutic options for countless patients.We are looking for talented individuals who thrive in a collaborative environment, embrace a dynamic workplace culture, and are dedicated to advancing innovative cellular therapies that will significantly impact patients' lives.The Director of Medical Writing will offer strategic and operational leadership across all Medical Writing initiatives to support BlueRock’s project portfolio from early development stages through to product registration.This role will be responsible for establishing and managing a cohesive Medical Writing function that produces high-quality regulatory documents in alignment with BlueRock’s global strategy, development timelines, and corporate objectives. The Director will lead an internal medical writing team, oversee vendor collaborations, and act as a key strategic partner to various departments including Regulatory Affairs, Pharmacovigilance, Clinical Development, Clinical Operations, Biometrics, Translational Science, and Technical Operations. Additionally, this role will play a crucial part in evolving capabilities such as AI-enabled medical writing, content reuse strategies, and collaborative models with Bayer teams.

Scholar Rock, Inc. is a pioneering biopharmaceutical firm dedicated to the discovery, development, and delivery of transformative therapies for individuals suffering from serious diseases with significant unmet medical needs. As a recognized leader in the biology of the transforming growth factor beta (TGFβ) superfamily of proteins, Scholar Rock is committed to advancing innovative treatments where the modulation of protein growth factors is crucial. Over the last decade, we have developed a robust pipeline aimed at redefining the standard of care for neuromuscular conditions, cardiometabolic disorders, cancer, and other diseases where growth factor-targeted therapies can radically change patient outcomes. Scholar Rock is the first and only company to demonstrate clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). Our commitment to unlocking unique therapeutic strategies is driven by our proprietary platform, which has generated novel monoclonal antibodies designed to modulate protein growth factors with remarkable precision. By leveraging cutting-edge scientific advancements in therapeutic areas that have historically been overlooked by conventional treatments, Scholar Rock tirelessly works to create new avenues for patient care. Discover more about our innovative approach at ScholarRock.com and follow us on @ScholarRock and LinkedIn.Position Overview:The Senior Medical Director of Drug Safety & Pharmacovigilance plays a critical role within the company, significantly influencing the development and lifecycle management of drug projects. This position is responsible for defining and implementing safety strategies and providing expert guidance during both pre- and post-approval phases for assigned products. The Senior Medical Director will proactively lead risk management initiatives in compliance with global regulatory standards, continuously evaluating safety data, conducting signal detection, and managing the safety profiles of compounds. Additionally, this role will involve close collaboration with cross-functional teams to achieve project objectives within established timelines and quality standards.

We are seeking a skilled and experienced Senior Medical Writer to join our dynamic team at Artech Information Systems LLC. In this role, you will be responsible for producing high-quality, scientifically accurate documents that communicate complex medical information clearly and effectively. You will collaborate with cross-functional teams to develop and deliver regulatory submissions, clinical study reports, and other essential documentation.

About BlueRock TherapeuticsBlueRock Therapeutics LP is at the forefront of cell therapy innovation, dedicated to developing groundbreaking treatments for neurological and ophthalmic disorders. Our clinical-stage investigational therapies, including bemdaneprocel (BRT-DA01) for Parkinson’s disease and OpCT-001 for primary photoreceptor diseases, represent a significant leap in medical science. Founded in 2016 through a partnership between Versant Ventures and Leaps by Bayer, we are driven by a culture of resilience, urgency for transformation, integrity, and a deep commitment to community.Our VisionWe specialize in harnessing the potential of universal pluripotent stem cells, guiding their differentiation into functional cells for allogeneic cellular therapies aimed at a wide range of conditions. Our passion lies in advancing cellular and gene therapy, ultimately improving the lives of millions of patients by delivering innovative treatment options.We are on the lookout for dynamic individuals who thrive in a collaborative and vibrant environment, and who are dedicated to pioneering cellular therapies that can transform patient outcomes.As we continue to make strides in cellular therapies, we are inviting an exceptional professional to join our Clinical Development team, playing a crucial role in overseeing preclinical, translational IND-enabling, and clinical development activities for our neurology programs.The Associate Medical Director of Neurology will lead scientific and medical initiatives for our neurology programs. Reporting directly to the Vice President of Clinical Development, this individual will collaborate closely with program leads and subject matter experts to enhance our development pipeline. The ideal candidate will serve as a clinical and scientific authority, fostering both internal and external partnerships to drive program success.

Costello Medical is hiring an IT Administrator based in Cambridge, England. This position plays a central role in keeping the company’s IT infrastructure stable and secure, supporting the daily work of teams across the business. Key responsibilities Maintain and oversee IT systems throughout the organization Troubleshoot technical issues, including both hardware and software problems Apply solutions to improve system performance and strengthen security Role focus This role centers on supporting smooth operations by resolving IT challenges and ensuring reliable technology for colleagues. Company mission Costello Medical provides medical communications and data analysis services. The IT Administrator helps support this mission by making sure technology works efficiently and securely.

Join Flagship Pioneering Inc. as the Director/Senior Director of Compensation, where you will lead the strategic development and execution of our compensation programs. Your role will involve designing competitive compensation structures, ensuring alignment with industry standards, and driving initiatives that enhance employee engagement and performance. You will collaborate with senior leadership to shape compensation policies that reflect our commitment to attracting and retaining top talent.

Scholar Rock is a pioneering biopharmaceutical enterprise dedicated to the discovery, development, and delivery of transformative therapies for individuals with serious diseases that are significantly underserved. Renowned for its leadership in the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins, Scholar Rock is committed to advancing innovative treatments where protein growth factors are essential. Over the last decade, the company has established a robust pipeline aimed at enhancing the standard of care for various conditions including neuromuscular diseases, cardiometabolic disorders, and cancer, where growth factor-targeted therapies can make a monumental difference. Scholar Rock stands out as the only organization to demonstrate clinical proof of concept for a muscle-targeted therapy in spinal muscular atrophy (SMA). Our dedication to exploring fundamentally novel therapeutic strategies is driven by the application of a proprietary platform that has yielded innovative monoclonal antibodies designed to modulate protein growth factors with remarkable selectivity. By leveraging advanced scientific approaches in historically neglected disease areas, Scholar Rock is committed to unlocking new opportunities for patients. Discover more about our mission at ScholarRock.com and connect with us on @ScholarRock and LinkedIn.Position Overview:The Medical Director, reporting to the VP of Clinical Research, will play a vital role in the early development team, responsible for steering clinical development initiatives for product candidates from IND to Proof-of-Concept. This role demands a highly driven physician scientist with hands-on experience in advancing product candidates aimed at delivering impactful medicines. The successful candidate will provide medical leadership for clinical development activities related to follow-on indications for apitegromab and new product candidates, aligning with corporate strategy.

About Flagship Pioneering, Inc. Flagship Pioneering is at the forefront of innovation, dedicated to inventing and nurturing platform companies that have the potential to revolutionize human health, sustainability, and more. Since our inception in 2000, we have successfully launched over 100 companies that tackle some of the world's most pressing challenges, such as vaccinating billions against COVID-19, curing difficult diseases, enhancing human health, preventing illness, and improving agricultural resilience and sustainability. Our commitment to impactful innovation has earned us recognition on FORTUNE's 'Change the World' list, highlighting companies that make a significant social and environmental impact, and we have appeared on Fast Company's annual list of the World’s Most Innovative Companies. Position Summary: We are looking for a passionate and experienced individual to join our Communications and Public Affairs team as the Senior Director of Communications. In this role, you will spearhead the development and implementation of communications and branding strategies for a selection of companies within Flagship Pioneering's diverse portfolio. The ideal candidate will possess a robust background in biotech corporate communications and excel in a fast-paced, startup atmosphere. This is a remarkable opportunity to influence the trajectory of groundbreaking life sciences and technology firms across human health, agriculture, and AI sectors. This full-time role requires in-office presence four days a week in Cambridge, MA. Key Responsibilities: Provide strategic counsel to the founders and leadership of emergent Flagship companies (Flagship NewCos) in developing their brand, voice, foundational messaging, and overall communication strategies. Oversee brand development, visual identity, and website design for NewCos, collaborating with external agencies. Create and implement tailored, integrated communication strategies for company launches, encompassing all written content, media engagement, and social media components. Manage PR agency support as necessary. Develop and execute communication strategies for both NewCos and more established companies (Flagship GrowthCos), including milestone announcements, internal communications, social and digital media strategies, speaking opportunities, and issue management, in close collaboration with company leadership.

Role SummaryResponsibilities: You will play a pivotal role in enhancing the company’s commercial operations and business development initiatives while supporting our objective of establishing enduring strategic partnerships with our clients.Salary: £24,500 to £26,000 per annum, commensurate with your experience.Benefits: Enjoy discretionary profit-sharing bonuses disbursed biannually, flexible working arrangements, a generous holiday allowance, private medical insurance, critical illness coverage, income protection, and full sponsorship for external training opportunities. For more details, visit our benefits page.Role Type: Available as either full-time or part-time, permanent roles.Start Date: We are looking for candidates who can start in April or May 2026; please indicate your availability in your application.Application Deadline: Submit your application by Friday 8th March 2026. We will conduct interviews shortly after this date.Location: This opportunity is based at our Global Headquarters in Cambridge.About the RoleAt Costello Medical, a globally recognized B Corp certified medical communications firm, we are experiencing rapid growth driven by our unwavering commitment to exceptional customer service and high-quality deliverables. To facilitate this expansion, we seek a motivated Business Administrator to become part of our dynamic and collaborative External Engagement team.In this capacity, you will assist in various administrative tasks related to our business development and commercial processes, including:Commercial & Negotiation SupportAssisting in the administration of commercial negotiations within the pharmaceutical and healthcare industries by preparing necessary materials, compiling historical communications, and coordinating essential documents.Utilizing Excel to create pricing documents (rate cards) by extracting data, calculating new rates, and drafting proposals.Maintaining and updating commercial data in our internal systems.Overseeing the management of the team’s shared inbox, responding to inquiries, directing requests to appropriate team members, and ensuring timely communications.Coordinating and supporting regular team meetings focused on commercial topics, including scheduling, agenda preparation, note-taking, and action item circulation.Business Development SupportAssisting in business development initiatives and campaigns for our client-facing teams.Conducting research on client pipelines and facilitating outreach efforts to enhance engagement.

Scholar Rock is a pioneering biopharmaceutical entity dedicated to the discovery, development, and delivery of transformative therapies aimed at addressing significant unmet medical needs. As a recognized leader in the biology of the transforming growth factor beta (TGFβ) superfamily, and inspired by the structural resemblance of a scholar rock to protein formations, our clinical-stage company is devoted to advancing groundbreaking treatments that leverage protein growth factors. Over the last decade, we have established a robust pipeline designed to redefine the standard of care for conditions such as neuromuscular diseases, cardiometabolic disorders, and cancer, where growth factor-targeted therapies can make a substantial impact. Scholar Rock stands out as the sole organization demonstrating clinical proof of concept for a muscle-targeted therapy in spinal muscular atrophy (SMA). Our commitment to unlocking innovative therapeutic pathways is underscored by the extensive application of our proprietary platform, which has yielded novel monoclonal antibodies to selectively modulate protein growth factors. By harnessing cutting-edge scientific advancements in traditionally underserved disease areas, we strive each day to create new possibilities for patients. Discover more about our mission at ScholarRock.com and connect with us on @ScholarRock and LinkedIn.Position Overview:As Scholar Rock embarks on a pivotal phase with the impending launch of our inaugural commercial product, we are in search of a strategic and operationally-savvy Senior Director of Global Facilities. This role transcends purely administrative functions; we require a visionary builder who comprehends the intricacies of scaling infrastructure within a rapidly evolving biotech setting while adeptly navigating day-to-day operational challenges.With facilities strategically located worldwide and poised for future growth, you will be responsible for ensuring our environments are safe, compliant, efficient, and conducive to supporting both research and commercial initiatives. If you are a proactive self-starter who thrives in dynamic, transformative organizations and is eager to contribute significantly, this opportunity allows you to apply your expertise, learn extensively, and make a meaningful impact.

Your Role at Lila Sciences Lila Sciences stands at the forefront of scientific innovation, operating as the world’s first scientific superintelligence platform and autonomous laboratory dedicated to life sciences, chemistry, and materials science. Our mission is to revolutionize the process of scientific discovery by seamlessly integrating AI into every facet of the scientific method, empowering researchers to address humanity’s most pressing challenges in health, climate change, and sustainability at unprecedented speed and scale. Position Overview As the Director/Senior Director of Applied AI, you will spearhead the establishment of our foundational Applied AI team, responsible for refining and adapting our AI models for practical product deployment. You will ensure their safe integration with diverse customer datasets and oversee the development of high-performance interfaces, including chat experiences and inference endpoints like gRPC, HTTP, and PCP servers. Reporting directly to the CTO, you will manage the complete roadmap from data acquisition to model deployment, collaborating closely with Research, Product, Software, Application, Safety, and Security teams to deliver models that are functional, quantifiable, and dependable. Key Responsibilities Lead and mentor a high-performing Applied AI team to produce exceptional scientific reasoning models for consumer applications. Manage an end-to-end model customization pipeline to generate impactful models from Lila’s base models for high-value applications, including inference, chat, and API integration. Develop a comprehensive evaluation framework to facilitate ongoing model enhancement and performance optimization. Collaborate with cross-functional teams to define project requirements, deliver customer proofs of concept (POCs), and transition successful pilots into scalable products. Establish technical standards, documentation, and incident response protocols for AI systems in production. Recruit, mentor, and foster a diverse and inclusive team environment. Qualifications for Success 8+ years of experience in applied machine learning or ML systems, with a minimum of 3 years in a leadership role; proven track record of deploying large language models (LLMs) into production. Extensive experience in fine-tuning and evaluating large-scale models for customer interactions. Production inference expertise, including familiarity with serving frameworks (Triton, vLLM, TGI, Ray, Kubernetes), GPU orchestration, caching, and observability. Strong understanding of data privacy and security best practices in multi-tenant systems. Preferred Qualifications Experience with instruction fine-tuning and optimization techniques. Proficiency in developing chat user experiences, implementing guardrails, tool/function calling, and managing long-context interactions.

Company Overview:Atavistik Bio is a leading, privately-held biotechnology firm at the forefront of developing groundbreaking precision allosteric therapeutics aimed at addressing significant unmet medical needs. With our innovative AMPS™ platform, we swiftly uncover functional cryptic pockets across various target classes, enhancing the speed of medicine development. Our growing portfolio of allosteric therapeutics shows promise for superior efficacy and tolerability, leveraging the unique advantages of allostery.Atavistik Bio is spearheaded by a team of seasoned drug hunters with extensive experience in bringing marketed small molecule therapies to fruition, backed by distinguished investors including The Column Group, Nextech Invest, Lux Capital, and Regeneron Ventures.Position Overview:We are on the lookout for a dynamic and strategic Senior Director of Toxicology to become a vital member of our development team. This role involves collaborating with a passionate group of adept scientists within a vibrant, rapidly evolving organization. Reporting directly to the Chief Scientific Officer, the successful candidate will oversee the design, execution, and analysis of all nonclinical safety studies essential for discovery, IND-enabling, and late-stage clinical development. This position will lead toxicology efforts across diverse programs, ensuring the delivery of high-quality data packages for regulatory submissions. Join us in shaping a pioneering toxicology function in an exhilarating clinical-stage environment.

Join Amylyx Pharmaceuticals, Inc. as the Senior Director of Patient Services, where you will lead initiatives aimed at enhancing patient experience and access to our innovative treatments. You will be responsible for developing and implementing strategic plans that prioritize patient needs, while collaborating with cross-functional teams to ensure the highest quality of services is delivered.

Scholar Rock is a pioneering biopharmaceutical company dedicated to discovering, developing, and delivering transformative therapies for patients with serious diseases that exhibit significant unmet needs. Renowned globally for our expertise in the biology of the transforming growth factor beta (TGFβ) superfamily, we are committed to advancing innovative treatments where protein growth factors are critical. Over the last decade, we have built a robust pipeline that has the potential to redefine the standard of care for neuromuscular diseases, cardiometabolic disorders, cancer, and various other conditions where growth factor-targeted therapies can make a significant impact.Scholar Rock uniquely demonstrated clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). Our dedication to exploring fundamentally different therapeutic avenues is driven by the innovative application of our proprietary platform, which has produced novel monoclonal antibodies that modulate protein growth factors with remarkable precision. By leveraging cutting-edge scientific research in disease areas historically underserved by conventional treatments, we work tirelessly to create new opportunities for patients. Discover more about our approach at ScholarRock.com and follow us on @ScholarRock and on LinkedIn.Position Overview:The Director or Senior Director of Regulatory Strategy, reporting directly to the Senior Vice President, Global Head of Regulatory Affairs, will be responsible for formulating and executing the global regulatory strategy for designated clinical and pipeline programs. As a subject matter expert, this individual will engage with program teams to identify regulatory risks and opportunities, thereby informing strategic direction and planning. The ideal candidate will spearhead interactions with regulatory authorities, overseeing the preparation and submission of all regulatory documentation and correspondence.

Join AbbVie as a Senior Director of Search & Evaluation in Neuroscience, where you will lead transformative initiatives in drug discovery and development. You will play a pivotal role in evaluating innovative neuroscience projects and establishing strategic partnerships that will drive our mission to improve patient outcomes.

Join Integrated Resources, Inc. as a Medical Writer, where you will play a pivotal role in the development of high-quality medical documentation. In this dynamic position, you will collaborate with cross-functional teams to produce regulatory documents, clinical study reports, and other materials that adhere to industry standards.