Senior Clinical Scientist at Alkeus | Cambridge, MA

Alkeus Pharmaceuticals, Inc. is a pioneering clinical-stage biotechnology firm headquartered in Cambridge, Massachusetts, dedicated to the advancement of groundbreaking therapies aimed at addressing critical ocular diseases with significant unmet medical needs. Established in 2010, Alkeus has been diligently developing its flagship compound, gildeuretinol acetate (ALK-001), which has received designation as a breakthrough therapy and orphan drug status from the U.S. Food and Drug Administration. Gildeuretinol is currently being assessed across various clinical trials for the treatment of Stargardt disease and geographic atrophy (GA) resulting from age-related macular degeneration (AMD), a leading cause of blindness in the United States.Position Summary:The Senior Clinical Scientist will take charge of providing scientific leadership and oversight for late-stage (Phase 3) clinical development programs focused on rare diseases in the field of ophthalmology. This role is crucial to maintaining scientific integrity, ensuring regulatory compliance, and successfully executing pivotal clinical trials necessary for global registration.As a key individual contributor, the Senior Clinical Scientist will act as a primary scientific collaborator throughout the clinical development process, closely partnering with clinical operations, biostatistics, regulatory affairs, and safety teams to translate strategic objectives into high-quality Phase 3 studies. This position is ideally suited for a seasoned professional with a proven track record in late-stage clinical development, particularly in rare diseases and/or ophthalmology.

Alkeus Pharmaceuticals, a pioneering biopharmaceutical company in Cambridge, MA, is seeking a dynamic and experienced Vice President of Clinical Operations to lead our clinical strategy and execution. This leadership role will be crucial in advancing our innovative therapies through clinical trials and regulatory pathways.The ideal candidate will possess a robust background in clinical operations, with demonstrated success in managing complex clinical programs and ensuring compliance with regulatory standards. You will work closely with cross-functional teams to drive clinical development strategies, oversee operational execution, and maintain high-quality standards throughout our clinical trials.

As a Clinical Trial Manager at Alkeus Pharmaceuticals, you will play a pivotal role in overseeing clinical trials from initiation to completion. You will ensure compliance with regulatory standards, manage timelines, and collaborate with cross-functional teams to deliver high-quality results in a timely manner.

Join eGenesis as a Senior Clinical Research AssociateAt eGenesis, we are at the forefront of innovation in biotechnology, developing human-compatible engineered organs to combat the critical global organ shortage. Our cutting-edge genome engineering platform allows for extensive gene modifications, effectively removing biological barriers and introducing protective human transgenes. Our leading program, EGEN-2784, involves a genetically engineered porcine kidney currently under a multi-patient Expanded Access study at Massachusetts General Hospital (MGH). We are proudly headquartered in Cambridge, MA, and are dedicated to making a significant impact on healthcare.We are currently in search of a highly skilled Senior Clinical Research Associate with over 4 years of experience in monitoring intricate clinical trials within pharmaceutical, biotechnology, and CRO settings. The ideal candidate will demonstrate proven expertise in managing investigative sites, conducting site qualifications, initiation, routine monitoring (both on-site and remote), and closeout visits while ensuring adherence to ICH-GCP, regulatory requirements, and study protocols. You will be tasked with overseeing site performance, preserving data integrity through source data verification and CRF review, and maintaining timely documentation in eTMF, CTMS, and EDC systems. Additionally, you will support site start-up activities, provide training for investigators and site staff, and offer operational guidance to academic medical centers, particularly those with limited IND experience. The right candidate will possess strong capabilities in identifying operational risks, implementing effective mitigation strategies, and managing high volumes of clinical data to uphold patient safety, data quality, and study compliance. Reporting to the Lead CRA or Clinical Operations leadership, you will execute monitoring strategies and facilitate consistent oversight of assigned sites. We value collaboration and are looking for a team player who can work closely with investigative sites and cross-functional teams to enhance enrollment, address operational challenges, and ensure inspection readiness.

Join Alkeus Pharmaceuticals, Inc., a pioneering clinical-stage biotech firm dedicated to the innovation of transformative therapies aimed at addressing serious ocular diseases with significant unmet needs. Established in 2010 and based in the vibrant city of Cambridge, Massachusetts, we are at the forefront of advancing our flagship compound, gildeuretinol acetate (ALK-001). Recognized as a breakthrough therapy and awarded orphan drug status by the U.S. Food and Drug Administration, gildeuretinol is currently undergoing rigorous evaluation in numerous clinical trials targeting Stargardt disease and geographic atrophy (GA) secondary to age-related macular degeneration (AMD)—a leading cause of blindness in the United States.We are actively seeking passionate professionals who aspire to contribute to our mission and play a pivotal role in shaping the future of Alkeus Pharmaceuticals.We encourage you to apply and submit your resume for general consideration. #LI-DNIAlkeus Pharmaceuticals, Inc. is an equal opportunity employer and considers all qualified applicants for employment without regard to any characteristic protected by applicable law. We participate in E-Verify and conduct background checks as a part of our employment process.

Join Alkeus Pharmaceuticals, a pioneering biopharmaceutical company dedicated to transforming the lives of patients with rare diseases. We are seeking a dynamic and visionary Medical Director to lead our clinical development activities, providing strategic direction and oversight for our innovative programs.As the Medical Director, you will collaborate with cross-functional teams, engage with key opinion leaders, and contribute to the development of cutting-edge therapies. This is an exceptional opportunity for a dedicated professional looking to make a significant impact in the field of rare diseases.

About the Role farsyt is looking for a Senior Insurance Producer in Cambridge, MA. This position focuses on building strong client relationships, understanding each client’s insurance needs, and recommending solutions that support their financial well-being. What You Will Do Develop and maintain relationships with clients, both new and existing Assess client insurance requirements and recommend appropriate coverage options Support clients throughout the insurance process, ensuring clear communication and reliable service Contribute to business growth by identifying opportunities to expand client portfolios

Iterative Health is at the forefront of healthcare technology and services, dedicated to accelerating clinical research that significantly transforms patient outcomes. With our unique Iterative Health Site Network comprising over 70 premier clinical research sites across the US and Europe, we expedite the market introduction of innovative gastrointestinal (GI) and hepatology therapies. Our mission centers on empowering our partner sites with tech-enabled services that foster their growth and success. By integrating deep clinical trial expertise with advanced AI capabilities, we enable research teams and study sponsors to broaden and accelerate access to novel therapeutics for patients in need.We are in search of a dynamic and detail-oriented Payroll Specialist to join our team in a full-time capacity. The ideal candidate is an enthusiastic self-starter driven to set and achieve goals while taking initiative in their role. This professional will play a crucial role in minimizing manual processing risks, ensuring compliance with regulations, automating systems, and overseeing day-to-day payroll operations. This position offers an excellent opportunity to enhance your payroll and accounting expertise while contributing to the accuracy and efficiency of our financial operations and supporting broader financial reporting and compliance efforts.

Join Engine as a Senior Associate in Community OperationsAt Engine, we empower visionary founders who are tackling the world's most critical challenges in areas such as climate change, health, and advanced technologies. Our commitment includes providing robust support through founder programs, access to shared infrastructure and labs, and the opportunity to connect with a diverse national network of corporate partners, investors, and industry experts.

Company Summary:At FL122, we are at the forefront of pioneering genomic technologies that redefine human health and assisted reproduction. Founded by the innovative Flagship Pioneering, we are dedicated to creating, funding, and nurturing first-in-category life sciences companies. Our portfolio includes over 100 groundbreaking companies developed over the past two decades, such as Moderna (MRNA), Generate Biomedicines, Tessera Therapeutics, and Quotient Therapeutics. We pride ourselves on being an equal opportunity employer.Position Summary:We are in search of our inaugural Computational Genomics Scientist to spearhead vital research that will underpin our scientific platform. As an early-stage team member, you will enjoy significant ownership of your work, shaping our analytical strategy from the ground up by integrating genomics, statistical genetics, and advanced modeling techniques. Your responsibilities will encompass the comprehensive delivery of computational research projects, including design, execution, interpretation, and communication of results to senior leadership. We seek a resourceful individual who thrives in a fast-paced, agile environment and possesses a proactive mindset. The ideal candidate will combine technical expertise with a growth-oriented approach, meticulous attention to detail, and a relentless drive for excellence. Collaboration is essential in our startup environment, where all team members work closely to push the boundaries of scientific discovery.

Our Mission Speechify aims to make information accessible through audio. The platform lets users listen to articles, documents, and books on their own schedule, at work, while commuting, or during downtime. Like streaming changed audio entertainment, Speechify is changing how people consume written content. The company leads its category and continues to grow rapidly. Role Overview The Senior Software Engineer, Core Experiences, joins a team responsible for the foundational services and SDKs that power Speechify’s product across multiple platforms. This position suits engineers who enjoy working where product and infrastructure meet, and who bring a strategic approach to designing APIs and systems that improve the user experience. What You Will Do Work closely with Product Teams to define project scopes, streamline feedback loops, solve integration and user experience challenges across teams, and deliver solutions through Speechify’s cross-platform SDK. Improve existing features by optimizing performance, reducing load times, and refining parsing through new abstractions and algorithm updates. Build and deploy cloud functions, lightweight backend services, and tasks using Kotlin. Location This role is based in Cambridge, MA, USA.

Are you passionate about advancing the field of machine learning? Join our team at Altos Labs as a Machine Learning Scientist or Senior Machine Learning Scientist. In this role, you will leverage your expertise to drive innovation and development in cutting-edge research projects. Collaborate with a multidisciplinary team to push the boundaries of machine learning technology.

Teamwork makes the stream work. Roku is revolutionizing the way the world enjoys television.As the leading TV streaming platform in the U.S., Canada, and Mexico, Roku is committed to empowering every television worldwide. We pioneered the streaming experience and strive to connect consumers with their favorite content, enable content creators to build and monetize expansive audiences, and offer advertisers unique opportunities to engage.From your first day at Roku, you will contribute significantly to our mission. We are a rapidly growing public company where every individual plays a crucial role. You will have the chance to delight millions of TV streamers globally while gaining invaluable experience across diverse disciplines. About the Role Roku is seeking a Senior Data Scientist to join our Core Analytics team, supporting the Viewer Product division. In this position, you will utilize data analytics to enhance our Live product. You will manage comprehensive analytics that influence how viewers discover, engage with, and return to Live experiences on Roku. Collaborating closely with product management and engineering, you will identify opportunities to create new features, drive their adoption, and generate value for Roku. This role requires an individual who is data-driven, detail-oriented, and possesses exceptional problem-solving skills. What You Will Be Doing

About Lila Sciences Lila Sciences stands at the forefront of innovation with the world's first scientific superintelligence platform and autonomous laboratory dedicated to life sciences, chemistry, and materials science. Our mission is to revolutionize scientific discovery, leveraging AI to enhance every facet of the scientific method. By introducing scientific superintelligence, we aim to address humanity's most pressing challenges while accelerating advancements in human health, climate, and sustainability. Discover more about our vision at www.lila.ai. If you resonate with our mission and possess some of the qualifications listed below, we invite you to apply and join our dynamic team. Your Role and Impact at Lila As a Robotics Scientist at Lila, you will spearhead the research and development of autonomous robotic systems that constitute the intelligent backbone of our scientific superintelligence platform. Your innovations in novel algorithms and intelligent robotic solutions will enable seamless interactions between robotic systems and human scientists, driving fully autonomous workflows for groundbreaking scientific discovery. You will integrate cutting-edge robotics, machine learning, and systems engineering into your work, fostering a new era of scientific exploration. Your Contributions Will Include Designing and developing autonomous robotic systems for transport and workcell operations, incorporating sophisticated path planning, navigation, and motion planning algorithms. Creating production-level mobile manipulation platforms utilizing ROS/ROS2 and modular robotic architectures. Enhancing robotic perception by integrating diverse sensing modalities, including 3D vision, LIDAR, and tactile sensors, to facilitate robust and adaptable task execution. Employing simulation environments to model, test, and optimize task planning, scheduling, and robot behaviors across varied lab scenarios. Collaborating with AI, mechanical, and software engineering teams to transform theoretical robotics research into practical autonomous systems. What You Will Need to Succeed A Ph.D. in Robotics, Computer Science, Mechanical or Electrical Engineering, or a closely related field, or equivalent research experience. In-depth expertise in motion planning, path planning, and navigation for both manipulation and mobile robotics. Proficient in ROS/ROS2, C++, and Python, with practical experience in constructing robotic systems for real-world applications. Comprehensive understanding of perception systems and sensor integration, including cameras, LIDAR, and tactile sensors.

As a Cake Decorator at Shaw's Supermarkets, you will play a vital role in delivering exceptional customer service at our Bakery service counter. Your primary responsibility will involve not only decorating cakes using both freehand techniques and decorating kits but also engaging with customers to fulfill their bakery needs. You will stay updated on product prices, ingredients, and availability, and embody a friendly, knowledgeable, and responsive attitude to enhance customer satisfaction.Your duties will encompass preparing, baking, and packaging bakery products, ensuring they are visually appealing and properly stocked in display cases for customer purchase. You will interact with customers directly, providing personalized service and effectively handling orders. Additionally, you will maintain the cleanliness and organization of the Bakery area, ensuring a sanitary and inviting environment.Key Responsibilities:Expertly decorate cakes and create frosting, ensuring high-quality presentation.Provide courteous service in a fast-paced environment, both independently and as part of a team.Utilize retail selling techniques to enhance customer engagement and increase sales.Operate various bakery equipment, including ovens and mixers, to prepare products for sale.Stock and maintain product displays, ensuring product quality through regular checks.Lift and manage bakery products, adhering to safety standards while working in varied temperature environments.Handle customer inquiries and orders efficiently, both in-person and over the phone.

Pioneering Medicines, part of Flagship Pioneering, develops a broad range of new treatments by applying advanced scientific platforms. The team combines deep drug development knowledge with creative approaches to uncover and advance new therapeutic ideas. Close collaboration with Flagship’s bioplatform companies and external partners helps align efforts with R&D priorities, aiming to move discoveries quickly toward development. Role overview The Senior Director, Head of Toxicology leads the toxicology function at Pioneering Medicines. This position sets and executes nonclinical safety strategies across a varied and fast-moving portfolio. The role covers both investigative and regulatory toxicology, supporting multiple therapeutic modalities. Key responsibilities Establish and oversee nonclinical safety strategies for a growing portfolio of drug candidates. Provide scientific and strategic guidance for investigative and regulatory toxicology activities. Collaborate with multidisciplinary teams to support candidate selection and preclinical development. Ensure programs are prepared for regulatory submissions and early clinical development. Requirements Strong analytical skills and scientific rigor. Clear, effective communication across teams and partners. Experience influencing projects from discovery through early clinical stages. This role is based in Cambridge, MA.

ABOUT VEG Founded in 2014, Veterinary Emergency Group (VEG) has a mission to revolutionize the emergency veterinary experience for both pets and their owners. With rapid nationwide expansion, our hospitals are open 24/7, 365 days a year, providing a supportive and compassionate environment for our patients and our team members, affectionately known as VEGgies. At VEG, we prioritize saying yes to your career aspirations in veterinary emergency medicine. Our innovative open-concept hospitals allow you to manage diverse emergency cases, including exotics, while delivering an immersive, customer-focused experience that ensures every pet and pet parent receives the care they deserve. We are proud to have been recognized as a certified Great Place to Work® in both 2025 and 2026. THE JOB As an Emergency Credentialed Veterinary Technician, you will be an integral part of a dynamic team that excels in high-pressure environments where every second matters. Your role will encompass handling a variety of cases, from the routine to the highly complex, collaborating closely with our veterinarians to provide exemplary, emotionally attuned care. You will be involved in triage, diagnostics, treatments, anesthesia, monitoring, and critical care nursing, all while offering a calm and compassionate presence to pet parents during their most challenging moments. This position is ideal for someone eager to apply their training, enhance their skills, and make a meaningful difference in the lives of both pets and their owners.

As an Associate Scientist at Mindlance, you will play a crucial role in advancing innovative scientific research and development. You will collaborate with a dynamic team of professionals to conduct experiments, analyze data, and contribute to cutting-edge projects. Your expertise will help drive discoveries that make a real difference in various fields.

At HyperLight, we are pioneering the commercialization of thin-film lithium niobate (TFLN) integrated photonics, a transformative technology that facilitates high-performance and scalable optical components across various fields including AI and datacom infrastructure, hyperscale computing, and quantum computing. Established in 2018 and supported by prominent venture capital, we are dedicated to advancing the mass deployment of TFLN photonics technology.Our flagship TFLN Chiplet™ platform represents a groundbreaking modular integrated architecture designed for scalability and manufacturability, ensuring seamless integration into complex systems. This platform provides an exceptional blend of performance and industrial readiness, allowing system developers to rapidly deploy our technology across diverse applications. We collaborate closely with our customers and suppliers throughout all phases—from conceptualization and design to prototyping and mass production—to ensure a smooth transition to TFLN photonic technology.We believe that our platform is a cornerstone in the golden age of integrated photonics, empowering humanity to reach new heights. Our world-class team comprises experts in engineering, business, and operations, all united by core values of integrity, innovation, collaboration, and practical solutions. Driven by a shared commitment to excellence, we embrace challenges with curiosity, humility, and a profound care for one another.Join us in making a significant impact in a dynamic, collaborative, and rapidly growing environment.

Role Overview farsyt is hiring an Account Executive in Cambridge, MA. This role centers on building and sustaining strong client relationships, making sure client needs are met while supporting company goals. The position involves working with a wide range of clients and offering solutions that fit their specific situations. What You Will Do Develop and maintain connections with both new and existing clients Identify and pursue new business opportunities Present farsyt’s products and services to potential and current clients Work closely with internal teams to deliver results that meet client expectations Who We’re Looking For Enthusiastic and proactive approach to client engagement Comfortable managing several projects and priorities at once Motivated to contribute to team and company growth