Scientist in Responsive Protein Engineering and Screening

Join Flagship Pioneering, Inc. as a Scientist specializing in Responsive Protein Engineering and Screening. In this pivotal role, you will leverage your expertise in protein design and molecular biology to innovate and optimize protein-based solutions. Your work will directly contribute to cutting-edge research and development projects aimed at addressing significant challenges in biotechnology.

Join AbbVie, a global biopharmaceutical company, as a Senior Scientist I in our Neuroscience division specializing in Biologics Screening. In this role, you will lead innovative research efforts to develop therapies that address unmet medical needs in the field of neuroscience.

Role overview Eurofins Scientific seeks an Associate Scientist in Cambridge with a focus on molecular biology and protein purification. This role supports ongoing research projects and daily laboratory operations, working closely with experienced scientists in a well-equipped environment. Key responsibilities Perform experiments in molecular biology and protein purification Manage laboratory workflows to ensure accuracy and reliability Work collaboratively with team members on research projects Support initiatives that advance scientific knowledge Work environment The position is based in a modern laboratory with advanced equipment and a team of specialists. Daily work involves hands-on research and collaboration within a supportive scientific community.

Korrobio seeks an Associate Scientist to join its Compound Management, Cell Screening, and NGS teams at 60 First St, Cambridge, MA 02141. This position supports key research activities and collaborates with scientists across several disciplines. Main responsibilities Support daily compound management tasks and keep detailed records of inventory and usage. Assist with cell screening workflows, ensuring accuracy and consistency in experiments. Contribute to Next Generation Sequencing (NGS) projects, helping maintain efficient and reliable processes. Collaboration This role involves close teamwork with scientists from multiple research areas. Careful handling of compounds, execution of cell-based assays, and participation in sequencing efforts all help advance ongoing projects.

Join Lila Sciences as a Senior Research Associate or Associate Scientist in the Protein Science department, focusing on our cutting-edge Antibody Platform. You will play a crucial role in advancing our research initiatives, contributing to the development of innovative antibody-based therapeutics. This position offers the opportunity to collaborate with a talented team dedicated to scientific excellence and the pursuit of transformative solutions in healthcare.

At Iterative Health, we are at the forefront of healthcare technology and services, committed to revolutionizing clinical research and enhancing patient outcomes. Our renowned Iterative Health Site Network comprises over 70 clinical research sites across the U.S. and Europe, dedicated to expediting the market introduction of groundbreaking gastrointestinal (GI) and hepatology therapies. We empower our partner sites through innovative, tech-enabled services, leveraging our extensive expertise in clinical trials and advanced AI to broaden and accelerate access to vital therapeutics for patients in need.About the RoleThe Manager, Pre-Screening plays a crucial role in overseeing the initial stages of patient engagement for Iterative Health studies. This position is responsible for monitoring key performance indicators related to screenings, randomizations, and overall funnel health. You will lead a dedicated team that conducts electronic health record (EHR) chart reviews to identify potential candidates for trial enrollment, ensuring that every study supported by Iterative Health receives optimal pre-screening assistance.

Your Role at Lila Sciences Lila Sciences is searching for a skilled Senior Research Associate with expertise in Protein Purification, Analytics, and Developability. You will play a crucial role in the establishment and daily functioning of a cutting-edge high-throughput protein characterization platform. This position involves optimizing biophysical characterization workflows, collaborating with cross-functional teams, and ensuring the generation of high-quality, reproducible data as you contribute to the advancement of Lila's Scientific Superintelligence platform. Key Responsibilities Execute and refine high-throughput workflows for protein characterization across various modalities, including antibodies, bi-specifics, and enzymes. Operate and maintain automated chromatography systems, utilizing Size Exclusion Chromatography (SEC), Hydrophobic Interaction Chromatography (HIC), and affinity chromatography via HPLC platforms. Conduct biophysical characterization using advanced techniques such as Dynamic Light Scattering (DLS), melting temperature analysis (DSF), binding assays (BLI/SPR), and capillary electrophoresis (CE-SDS, cIEF) to evaluate protein critical quality attributes. Support workflows for characterizing protein post-translational modifications (PTMs), ensuring thorough sample preparation and precise data capture. Collaborate with scientists, engineers, and automation specialists to identify and implement enhancements in the efficiency, robustness, and scalability of developability workflows. Innovate and adjust protocols to accommodate new protein formats, targets, and analytical strategies. Ensure rigorous data quality, documentation, and reproducibility in all experiments; actively participate in knowledge sharing and continuous improvement initiatives. Work closely with computational scientists to support data analysis pipelines, data processing, and the creation of predictive models for protein characteristics.

Imagine... being part of an innovative organization that cultivates and develops life sciences companies dedicated to pioneering groundbreaking technologies aimed at revolutionizing health care and sustainability. Company Overview Expedition Medicines is a dynamic, privately held, early-stage biotechnology company at the forefront of the Protein Editing field. We specialize in creating small molecules that modify protein structure and function to target currently undruggable options across various therapeutic strategies. Our advanced platform combines cutting-edge small molecule chemistry and chemoproteomic discovery technologies with Machine Learning (ML) to facilitate generative design. Backed by Flagship Pioneering, we leverage their vision, courage, and resources to propel Expedition Medicines from platform validation to impactful patient solutions. We seek passionate, collaborative, and determined problem solvers to join our mission! Role Overview: The Senior/Principal Scientist in Structural Biology will concentrate on determining protein-ligand complex structures using X-ray crystallography and cryo-electron microscopy (cryo-EM). This role involves delivering structural insights and collaborating with project teams to advance structure-based drug design and uncover the mechanisms of action of small molecules. Key Responsibilities: Design and implement structural biology strategies for multiple projects. Oversee the design, expression, and purification of protein constructs for structural determination. Develop and execute protocols to achieve high-quality crystals for X-ray crystallography. Create and implement protocols for grid optimization, data collection, and analysis in cryo-EM. Refine and communicate structures of protein-ligand complexes, collaborating with project teams to drive hit-to-lead and lead optimization processes. Manage contract research organizations (CROs) to ensure efficient delivery of protein expression and structural biology services. Enhance our capabilities and serve as a trusted authority in the field of structural biology.

Company Overview: Korro Bio is an innovative biopharmaceutical firm dedicated to pioneering a new realm of genetic therapies aimed at both rare and prevalent diseases through its proprietary RNA editing platform. Korro is actively cultivating a unique portfolio of programs designed to utilize the body's inherent RNA editing mechanisms for precise, transient single-base edits. By focusing on RNA rather than DNA, Korro is broadening the scope of genetic medicines, offering enhanced precision and tunability, which may lead to greater specificity and improved long-term tolerability. Through an oligonucleotide-based strategy, Korro aims to deliver its therapeutic solutions to patients by leveraging its proprietary platform, established delivery methods, manufacturing expertise, and recognized regulatory pathways for approved oligonucleotide medications. Headquartered in Cambridge, Massachusetts, we are a collaborative team united by a shared mission.Our values—Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity—are the backbone of our organization. These principles are not only practiced daily but also play a crucial role in our hiring process, ensuring Korro attracts exceptional talent and fosters a positive work environment. Join us in redefining possibilities in genetic medicine and making a profound impact on human health.Position Overview: Korro Bio is on the lookout for a driven and detail-oriented Associate Scientist to join our High-Throughput Screening and Next Generation Sequencing (HTS-NGS) operations team. This lab-based role requires a commitment to producing high-quality results within designated timelines. This is an exciting opportunity to engage with a dynamic group of skilled scientists and contribute to the advancement of next-generation RNA editing technology and therapeutics in a rapidly evolving biotech environment.

Your Role at Lila SciencesJoin our innovative Physical Sciences division, where you will spearhead the development of intelligent agent-driven systems designed to enhance AI-accelerated and AI-orchestrated process engineering across diverse industrial applications. In this pivotal role, your mission will be to create methodologies empowering AI agents to reason, design, simulate, optimize, and operate complex physical and chemical processes using both traditional and machine learning-driven process engineering tools. You will focus on building agentic infrastructures that facilitate AI systems in planning and executing multi-step process engineering workflows, which include process synthesis, flowsheet generation, steady-state and dynamic simulation, control strategy design, and techno-economic evaluation. Your contributions will significantly influence how Lila's scientific superintelligence addresses real-world challenges through closed-loop autonomous process engineering.Your ContributionsDesign and implement agentic frameworks supporting comprehensive process engineering workflows, encompassing process setup, simulation, optimization, and analysis.Create AI agents capable of autonomously planning, executing, and refining process engineering tasks utilizing existing tools such as steady-state and dynamic simulators, optimizers, and data systems.Investigate agentic strategies for advanced objectives, including process intensification, control co-design, real-time optimization, and closed-loop learning informed by operational data.Enhance the robustness, interpretability, and reproducibility of agent-driven process engineering workflows; develop internal tools for debugging, observability, validation, and auditability.Collaborate with interdisciplinary teams to apply agentic process engineering across a wide range of industrial applications.

Join our innovative team as a Senior Scientist where you'll drive critical research projects and make a significant impact in the field. We are seeking a highly motivated individual with a passion for scientific discovery and a strong background in relevant disciplines.

We are seeking a motivated and detail-oriented Bench Scientist to join our dynamic team in Cambridge. This entry-level position is an excellent opportunity for recent graduates or those new to the field of scientific research. As a Bench Scientist, you will play a crucial role in conducting experiments, analyzing data, and contributing to innovative projects. If you are passionate about science and eager to learn, we encourage you to apply!

Join Artech Information Systems LLC as a Scientist in Cambridge, where you will contribute to groundbreaking research and innovative solutions in a collaborative environment. Your expertise will help drive scientific advancements and enhance our projects.

AbbVie is seeking a talented and motivated Associate Scientist II or Scientist I to join our dynamic In Vivo Pharmacology team in Cambridge. As part of our innovative research environment, you will play a crucial role in advancing our understanding of pharmacological mechanisms through in vivo studies. This position offers an exciting opportunity to contribute to groundbreaking research that has the potential to transform patient care.

As an Associate Scientist III, you will play a crucial role in advancing our scientific research initiatives. You will collaborate with cross-functional teams to design, execute, and analyze experiments that contribute to our innovative projects. Your expertise will help drive our mission forward, ensuring that we continue to push the boundaries of scientific discovery.

Join our dynamic team at Integrated Resources Inc. as an Associate Scientist II, where you will play a crucial role in advancing our innovative projects. In this position, you will engage in various scientific experiments and analyses, contributing to the development of cutting-edge solutions.

We are seeking a dedicated and detail-oriented Bench Scientist to join our innovative team at Artech Information Systems LLC. This entry-level role is perfect for recent graduates or individuals looking to kickstart their career in scientific research. The Bench Scientist will be responsible for conducting experiments, analyzing data, and contributing to various projects that advance our understanding of scientific principles.

We are seeking a motivated and detail-oriented Bench Scientist to join our dynamic team in Cambridge. In this role, you will be responsible for conducting experiments, analyzing results, and contributing to various research projects. This is an excellent opportunity for a recent graduate or entry-level professional to gain valuable experience in a laboratory setting.

Join Integrated Resources Inc. as an Associate Scientist I, where you will contribute to innovative scientific research and development projects. As a pivotal part of our team, your role will involve conducting experiments, analyzing data, and collaborating with multidisciplinary teams to advance our scientific objectives.

We are seeking a highly motivated and detail-oriented Associate Scientist I to join our dynamic team in Cambridge. The ideal candidate will assist in the design and execution of experiments, analysis of data, and contribute to various projects within our research initiatives.