Director/Sr. Director HR Business Partner (Fractional Consultant)

Position Summary: Quotient is in search of a seasoned HR leader to fulfill the role of a fractional, part-time (3 days per week) on-site HR Consultant at our Cambridge, UK location. This role is structured as a consulting/independent contractor engagement rather than a permanent employment opportunity. The HR Consultant will work directly with the Consultant VP of HR based in the United States and will integrate as a vital part of the global HR function throughout the duration of the engagement. This consultant will act as the senior HR business partner for UK leadership, effectively translating enterprise-wide people strategies into actionable local initiatives, while fostering close collaboration with HR leadership based in the US. The consultant will be a pivotal HR thought partner to both C-level executives and the R&D leadership team, striving to enhance team structure, promote a performance-oriented mindset, and cultivate a team-centric culture. The role necessitates strict adherence to enterprise HR governance, ensuring that UK-based personnel practices, policies, and decisions align with global standards and receive appropriate leadership oversight. This engagement will not create a standalone UK HR function; instead, the consultant will operate within an established global HR framework. The ideal candidate will successfully balance strategic insight with practical implementation in a fast-paced, early-stage environment, aiding in the scaling of the organization while ensuring consistency, compliance, and cultural unity across different regions.

Flagship Pioneering seeks a Senior Director of Human Resources Business Partner based in Cambridge, MA. This role focuses on shaping and executing the people strategy for Flagship’s Pioneering Business Units. The Senior Director will work closely with business unit leaders and the broader HR team to influence key decisions and support organizational goals. What you will do Collaborate with business leaders to design and deliver people strategies for multiple business units Advise on leadership development, talent management, and succession planning Support organizational development and change management initiatives Participate in budgeting, compensation, and workforce planning discussions Guide efforts in performance management, employee engagement, and career growth Address employee relations and help shape internal communication strategies Reporting structure This position reports to the Vice President of HR.

Scholar Rock is a pioneering biopharmaceutical company dedicated to discovering, developing, and delivering transformative therapies for patients with serious diseases that exhibit significant unmet needs. Renowned globally for our expertise in the biology of the transforming growth factor beta (TGFβ) superfamily, we are committed to advancing innovative treatments where protein growth factors are critical. Over the last decade, we have built a robust pipeline that has the potential to redefine the standard of care for neuromuscular diseases, cardiometabolic disorders, cancer, and various other conditions where growth factor-targeted therapies can make a significant impact.Scholar Rock uniquely demonstrated clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). Our dedication to exploring fundamentally different therapeutic avenues is driven by the innovative application of our proprietary platform, which has produced novel monoclonal antibodies that modulate protein growth factors with remarkable precision. By leveraging cutting-edge scientific research in disease areas historically underserved by conventional treatments, we work tirelessly to create new opportunities for patients. Discover more about our approach at ScholarRock.com and follow us on @ScholarRock and on LinkedIn.Position Overview:The Director or Senior Director of Regulatory Strategy, reporting directly to the Senior Vice President, Global Head of Regulatory Affairs, will be responsible for formulating and executing the global regulatory strategy for designated clinical and pipeline programs. As a subject matter expert, this individual will engage with program teams to identify regulatory risks and opportunities, thereby informing strategic direction and planning. The ideal candidate will spearhead interactions with regulatory authorities, overseeing the preparation and submission of all regulatory documentation and correspondence.

Director of Business Development - USVCLS: Accelerating the Path to PatientsSince 1997, VCLS has been at the forefront of supporting innovators in biotech, Medtech, and Healthtech on their journey from discovery to market. We have a simple yet ambitious mission: to accelerate the delivery of life-changing products to patients. With over 230 industry experts globally, we are dedicated to our long-term vision of delivering 500 new healthtech products by 2050.We are currently on the lookout for a Director of Business Development - US—an experienced, hands-on leader—to implement our US commercial strategy with clarity, intention, and urgency. This role is perfect for an individual who views business development as a consultative art rather than just a transactional process, characterized by curiosity, empathy, and a genuine passion for Life Sciences.Key Results & AccountabilitiesDriving Growth Through Consultative Partnerships Propel significant revenue growth by cultivating strong, trust-based relationships within the biotech, medtech, healthtech, and investment sectors. Take charge of the complete business development lifecycle including listening, identifying opportunities, crafting solutions, and securing strategic partnerships. Exhibit total ownership of the sales process ensuring every client feels comprehensively understood and supported without any handoffs or gaps.Excellence in Client Engagement & Sales OwnershipThis role is committed to delivering a world-class consultative experience, anchored in scientific curiosity and deep client insight: Actively listen and convert client challenges into clear, actionable opportunities. Ensure that clients connect with the right VCLS experts at the right time to maximize value. Coordinate internal teams to facilitate meaningful discussions rather than generic interactions. Lead the development of proposals with meticulous attention, ensuring that each reflects a deep understanding and tailored solutions. Maintain outstanding responsiveness, clarity, and follow-through throughout the client engagement journey.Market Presence & Brand Elevation Represent VCLS credibly and passionately across the US market. Establish a prominent presence at industry events, within accelerators, investor networks, and innovation hubs. Enhance VCLS’s reputation as a reliable partner in regulatory strategy, clinical development, CMC, evidence generation, and commercialization.Stakeholder Leadership & Internal Alignment Collaborate closely with Business Unit leaders, scientific experts, and senior management to ensure seamless execution of business development initiatives. Encourage cross-functional teamwork to optimize client outcomes.

Role overview The Senior Director of Business Analytics at Scholar Rock will play a central role in shaping the company's analytics strategy. Based in Cambridge, MA, this leader will drive efforts to support business growth and enable data-informed decision-making throughout the organization. What you will do Create and implement analytics strategies that support Scholar Rock’s goals Work closely with teams across the company to move data-driven projects forward Encourage and foster a strong analytics mindset among colleagues Use business analytics expertise to help set strategic direction and find ways to improve how the company operates Location This role is located in Cambridge, MA.

Pioneering Medicines, part of Flagship Pioneering in Cambridge, MA, focuses on developing a wide range of new treatments by building on Flagship’s scientific platforms. The team collaborates with Flagship companies to expand into new therapeutic areas, aiming to bring innovative medicines to more patients faster. With a strong drug development team and access to Flagship’s broader network, Pioneering Medicines generates new therapeutic ideas both internally and through strategic partnerships. Role overview The Director of Business Development Transactions leads strategic transactions for Pioneering Medicines and selected Flagship companies. This position requires strong influence across all organizational levels, excellent organizational and communication skills, and the ability to present complex information clearly. Scientific understanding, strategic thinking, and a collaborative approach are essential, as is comfort working in an entrepreneurial setting. What you will do Lead the structuring, negotiation, and execution of in-licensing, out-licensing, and asset sale transactions for Pioneering Medicines. Negotiate a range of strategic transactions for companies within the Flagship ecosystem. Direct due diligence and financial analysis to support new deals. Present key findings and recommendations to company leadership and investment decision-makers. Additional responsibilities Collaborate with the Partnering team and cross-functional leaders to shape and execute Flagship’s business development strategy. Build credibility across the organization with a deep understanding of biotech and pharmaceutical deal-making. Prepare opportunity assessments, including scientific and portfolio rationale, partnership frameworks, financial evaluations, competitive analysis, and deal term comparisons.

Amylyx Pharmaceuticals, Inc. is a clinical-stage company in Cambridge, MA, dedicated to developing treatments for diseases with significant unmet needs. The current pipeline focuses on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). The team values urgency, scientific rigor, boldness, curiosity, authenticity, engagement, and accountability. Role overview The Senior Director of Human Resources Business Partner – Commercial will report to the SVP of Human Resources and Talent Acquisition. This leader will work closely with the Chief Commercial Officer and the Commercial Leadership Team to shape, scale, and strengthen a high-performing commercial group. The role centers on aligning HR strategies with business needs as Amylyx prepares for commercial scale-up and key data milestones. Key responsibilities Advise the Chief Commercial Officer and Commercial Leadership Team to ensure HR initiatives support business objectives. Lead efforts to build and enhance the commercial function, supporting both corporate and field-based teams. Provide broad HR Business Partner support across the company, including Clinical, Technical Operations, and G&A functions as needed during the initial phase. Balance strategic leadership with hands-on HR work in a resource-limited and adaptive setting. Adapt responsibilities as the company grows, transitioning from broad HRBP support to a more specialized commercial HR leadership focus as milestones are achieved. What success looks like HR strategies effectively aligned with commercial and company-wide goals. Strong partnerships built with commercial and cross-functional leaders. Ability to navigate and support a streamlined, evolving organization. Demonstrated flexibility and willingness to handle both strategic and operational HR responsibilities. Location This position is based in Cambridge, MA.

Director of Accounting AdvisoryAs a Director at CFGI, you will collaborate directly with C-level executives from FTSE 100, mid-cap, and emerging companies. Your role will encompass leading project teams and engaging with clients alongside their Big 4 auditors, addressing all facets of engagements including report preparation, relationship management, and business growth initiatives. Take Charge of Your Career at CFGI:· Gain exposure to diverse industries and projects.· Make a significant business impact for your clients.· Manage projects from inception to completion.· Engage in a client-facing role that emphasizes interaction.· Continuously be challenged and learn within a collegial environment of top-tier experts.· Enjoy flexible work options tailored to specific engagements—office, remote, or client site.· Forge your own career path.· Find joy in your work! Your Expectations:· Collaborate with clients’ executive teams and auditors, acting as a subject matter expert to guide them through intricate accounting challenges.· Lead client engagement, ensuring delivery of operational due diligence for complex transactions such as IPOs, acquisitions, divestitures, stock offerings, and debt raises.· Ensure adherence to regulatory requirements while delivering financial and regulatory information.· Serve as a subject matter expert for new accounting standards on relevant projects.· Spearhead process improvement initiatives and implement necessary changes.· Mentor senior managers and consultants, serving as a moral and ethical role model, fostering professional growth, and providing constructive feedback.

Join Flagship Pioneering Inc. as the Director/Senior Director of Compensation, where you will lead the strategic development and execution of our compensation programs. Your role will involve designing competitive compensation structures, ensuring alignment with industry standards, and driving initiatives that enhance employee engagement and performance. You will collaborate with senior leadership to shape compensation policies that reflect our commitment to attracting and retaining top talent.

Your Role at Lila Sciences Lila Sciences is seeking a proactive and strategic Director of Facilities to oversee the daily operations and long-term management of our diverse facilities. You will be responsible for developing a scalable facilities strategy, ensuring safety and compliance across all sites, and managing budgets, capital planning, vendor relationships, and KPI reporting. This role is a pivotal cross-functional leadership position, with the opportunity to build and nurture a world-class facilities team that aligns with our growth and supports our scientific mission. Your Key Contributions Strategic Leadership Develop and implement a comprehensive facilities strategy that aligns with company growth, scientific initiatives, and operational risk management. Recruit, mentor, and lead a high-performing facilities organization, fostering a culture of safety, reliability, and continuous improvement. Team Development Directly manage and mentor facility managers, supervisors, and support staff, promoting a collaborative culture focused on employee engagement and professional development. Encourage cross-functional collaboration with business development, technology, finance, legal, and HR teams to drive informed decisions and improvements. Safety and Compliance Establish and maintain enterprise-wide safety standards and compliance across all facilities; lead audits and implement corrective actions. Direct capital planning, lifecycle management, and end-of-life decisions for critical equipment using ROI-driven analyses. Financial Management Oversee multi-site budgets, long-term capital planning, and KPI performance; optimize total cost of ownership. Manage the vendor lifecycle, including RFPs, contract negotiations, service level agreements, and vendor performance evaluations. Operations Excellence Standardize and enhance maintenance processes utilizing documentation, digital tools, and scalable playbooks; champion improvements focused on employee and occupant satisfaction. Implement governance, risk management, and compliance controls to ensure audit readiness and transparent reporting. Stakeholder Engagement Act as the primary liaison with clients, senior leadership, the Facilities Organization, and key business teams, translating facilities strategy into measurable business value. Collaborate with HR on workforce planning, safety training, and related initiatives.

At Flagship Pioneering, we are pioneering advancements in biotechnology, creating innovative platform companies that aim to transform the world. We unite visionary scientific minds with entrepreneurial leaders and provide the necessary capital to boldly tackle humanity's most pressing health and sustainability challenges. Our work spans vital areas, including cancer detection and treatment, as well as nature-positive agriculture. What distinguishes Flagship is our unique ability to advance biotechnology by integrating life sciences innovation, company creation, and capital investment. This unprecedented approach unites our scientific founders, entrepreneurial leaders, and professional capital managers around a streamlined process that fosters innovation for the greater good of people and the planet. Our portfolio has made significant strides in addressing critical global issues: from rapidly vaccinating billions against COVID-19 to curing persistent diseases, enhancing health outcomes, preventing illness, and boosting agricultural resilience and sustainability. Flagship has been honored twice on FORTUNE’s “Change the World” list and recognized by Fast Company as one of the World’s Most Innovative Companies. Why Choose Flagship?At Flagship Pioneering, we offer inspiring leadership, a vibrant company culture, competitive compensation, comprehensive benefits, generous paid time off, a beautifully designed office stocked with unlimited snacks and daily free lunches, and meaningful work that promotes endless career growth.

Join Iterative Health as our Director of Compliance, where you will play a pivotal role in shaping our compliance strategy and ensuring adherence to regulatory requirements. This leadership position will involve developing and implementing compliance programs, monitoring compliance performance, and liaising with regulatory bodies. You will lead a team of compliance professionals and collaborate with various departments to cultivate a culture of compliance within the organization.

The Company:At Nuvalent, we leverage our profound knowledge of chemistry to develop targeted therapeutics aimed at meeting the unique needs of cancer patients. As an innovative early-stage organization, we unite seasoned scientists and industry experts with a successful background in drug discovery, oncology development, and building impactful biopharmaceutical companies.The Role:In this pivotal position, reporting to the Vice President of Information Technology, the Director of IT Business Partnership for GXP will act as a key technology strategist. You will be responsible for ensuring that IT capabilities are effectively aligned with the business goals of all GXP-regulated departments (GMP, GLP, GCP) as we gear up for our commercial launch. This role demands extensive expertise in pharmaceutical IT systems, regulatory compliance, and the ability to convert intricate business needs into scalable technology solutions that bolster quality, compliance, and operational excellence.

Your Role at Lila Sciences Lila Sciences stands at the forefront of scientific innovation, operating as the world’s first scientific superintelligence platform and autonomous laboratory dedicated to life sciences, chemistry, and materials science. Our mission is to revolutionize the process of scientific discovery by seamlessly integrating AI into every facet of the scientific method, empowering researchers to address humanity’s most pressing challenges in health, climate change, and sustainability at unprecedented speed and scale. Position Overview As the Director/Senior Director of Applied AI, you will spearhead the establishment of our foundational Applied AI team, responsible for refining and adapting our AI models for practical product deployment. You will ensure their safe integration with diverse customer datasets and oversee the development of high-performance interfaces, including chat experiences and inference endpoints like gRPC, HTTP, and PCP servers. Reporting directly to the CTO, you will manage the complete roadmap from data acquisition to model deployment, collaborating closely with Research, Product, Software, Application, Safety, and Security teams to deliver models that are functional, quantifiable, and dependable. Key Responsibilities Lead and mentor a high-performing Applied AI team to produce exceptional scientific reasoning models for consumer applications. Manage an end-to-end model customization pipeline to generate impactful models from Lila’s base models for high-value applications, including inference, chat, and API integration. Develop a comprehensive evaluation framework to facilitate ongoing model enhancement and performance optimization. Collaborate with cross-functional teams to define project requirements, deliver customer proofs of concept (POCs), and transition successful pilots into scalable products. Establish technical standards, documentation, and incident response protocols for AI systems in production. Recruit, mentor, and foster a diverse and inclusive team environment. Qualifications for Success 8+ years of experience in applied machine learning or ML systems, with a minimum of 3 years in a leadership role; proven track record of deploying large language models (LLMs) into production. Extensive experience in fine-tuning and evaluating large-scale models for customer interactions. Production inference expertise, including familiarity with serving frameworks (Triton, vLLM, TGI, Ray, Kubernetes), GPU orchestration, caching, and observability. Strong understanding of data privacy and security best practices in multi-tenant systems. Preferred Qualifications Experience with instruction fine-tuning and optimization techniques. Proficiency in developing chat user experiences, implementing guardrails, tool/function calling, and managing long-context interactions.

About Flagship Pioneering, Inc. Flagship Pioneering is at the forefront of innovation, dedicated to inventing and nurturing platform companies that have the potential to revolutionize human health, sustainability, and more. Since our inception in 2000, we have successfully launched over 100 companies that tackle some of the world's most pressing challenges, such as vaccinating billions against COVID-19, curing difficult diseases, enhancing human health, preventing illness, and improving agricultural resilience and sustainability. Our commitment to impactful innovation has earned us recognition on FORTUNE's 'Change the World' list, highlighting companies that make a significant social and environmental impact, and we have appeared on Fast Company's annual list of the World’s Most Innovative Companies. Position Summary: We are looking for a passionate and experienced individual to join our Communications and Public Affairs team as the Senior Director of Communications. In this role, you will spearhead the development and implementation of communications and branding strategies for a selection of companies within Flagship Pioneering's diverse portfolio. The ideal candidate will possess a robust background in biotech corporate communications and excel in a fast-paced, startup atmosphere. This is a remarkable opportunity to influence the trajectory of groundbreaking life sciences and technology firms across human health, agriculture, and AI sectors. This full-time role requires in-office presence four days a week in Cambridge, MA. Key Responsibilities: Provide strategic counsel to the founders and leadership of emergent Flagship companies (Flagship NewCos) in developing their brand, voice, foundational messaging, and overall communication strategies. Oversee brand development, visual identity, and website design for NewCos, collaborating with external agencies. Create and implement tailored, integrated communication strategies for company launches, encompassing all written content, media engagement, and social media components. Manage PR agency support as necessary. Develop and execute communication strategies for both NewCos and more established companies (Flagship GrowthCos), including milestone announcements, internal communications, social and digital media strategies, speaking opportunities, and issue management, in close collaboration with company leadership.

Scholar Rock is a pioneering biopharmaceutical entity dedicated to the discovery, development, and delivery of transformative therapies aimed at addressing significant unmet medical needs. As a recognized leader in the biology of the transforming growth factor beta (TGFβ) superfamily, and inspired by the structural resemblance of a scholar rock to protein formations, our clinical-stage company is devoted to advancing groundbreaking treatments that leverage protein growth factors. Over the last decade, we have established a robust pipeline designed to redefine the standard of care for conditions such as neuromuscular diseases, cardiometabolic disorders, and cancer, where growth factor-targeted therapies can make a substantial impact. Scholar Rock stands out as the sole organization demonstrating clinical proof of concept for a muscle-targeted therapy in spinal muscular atrophy (SMA). Our commitment to unlocking innovative therapeutic pathways is underscored by the extensive application of our proprietary platform, which has yielded novel monoclonal antibodies to selectively modulate protein growth factors. By harnessing cutting-edge scientific advancements in traditionally underserved disease areas, we strive each day to create new possibilities for patients. Discover more about our mission at ScholarRock.com and connect with us on @ScholarRock and LinkedIn.Position Overview:As Scholar Rock embarks on a pivotal phase with the impending launch of our inaugural commercial product, we are in search of a strategic and operationally-savvy Senior Director of Global Facilities. This role transcends purely administrative functions; we require a visionary builder who comprehends the intricacies of scaling infrastructure within a rapidly evolving biotech setting while adeptly navigating day-to-day operational challenges.With facilities strategically located worldwide and poised for future growth, you will be responsible for ensuring our environments are safe, compliant, efficient, and conducive to supporting both research and commercial initiatives. If you are a proactive self-starter who thrives in dynamic, transformative organizations and is eager to contribute significantly, this opportunity allows you to apply your expertise, learn extensively, and make a meaningful impact.

The Opportunity: Join Relay Therapeutics as a Senior Medical Director, where you will be pivotal in propelling our clinical pipeline from IND to proof of concept and ultimately to registration. In this role, you will partner with senior medical staff to shape clinical strategies, design clinical trials, and ensure successful execution. Collaborating across various functions including clinical project management, regulatory affairs, clinical operations, biostatistics, data management, and medical writing, you will significantly contribute as Relay Therapeutics continues to advance product candidates into clinical settings. You will provide clinical leadership to R&D teams and closely collaborate with Development leadership. We are open to remote employees

Role Overview Lila Sciences is hiring a Director or Senior Director of Talent Acquisition in Cambridge, MA. This leader will guide the full recruitment function, shaping hiring strategy and team structure as the company grows. What You Will Do Lead and mentor the talent acquisition team, setting clear goals and supporting professional development Design and refine recruitment processes to attract and retain skilled professionals in biotechnology Develop strategies to build a diverse and creative workforce Collaborate with leadership to align hiring plans with company objectives About Lila Sciences Lila Sciences advances work in the biotechnology sector from its Cambridge, MA headquarters. The company values innovation, inclusion, and building strong teams to support its mission.

About Fulcrum Therapeutics Fulcrum Therapeutics, Inc. (NASDAQ: FULC) is a clinical-stage biopharmaceutical company based in Cambridge, MA. The team focuses on developing small molecule therapies for genetically defined rare diseases, with an emphasis on areas where patients have limited treatment options. The lead program, Pociredir, aims to increase fetal hemoglobin expression as a novel approach for treating sickle cell disease (SCD). Role Summary: Director of Biostatistics The Director of Biostatistics plays a key role within the Biometrics Department and reports to the VP of Biometrics. This position acts as the statistical subject matter expert for Fulcrum’s clinical development programs and individual studies. The director oversees statistical activities for outsourced clinical trials and ensures all work meets regulatory requirements. Main Responsibilities Serve as the lead statistician for clinical development programs and studies Oversee statistical activities in outsourced clinical trials Ensure compliance with regulatory standards in all statistical work Apply advanced study designs and statistical methods, including estimand strategies, endpoint selection, and approaches for missing data and multiplicity Work closely with teams across biometrics, clinical development, clinical operations, pharmacovigilance, medical writing, and regulatory affairs

Riverlane seeks a Director of IT Infrastructure to lead technology operations at its Cambridge, UK headquarters. This permanent, full-time position offers a hybrid work arrangement and a salary range of £100,000 to £130,000 depending on experience. Role overview This senior leadership role oversees all aspects of IT at Riverlane, from managing corporate systems to optimizing high-performance computing (HPC) infrastructure. The Director will shape IT strategy, execute plans, and collaborate with engineering, operations, security, and finance teams to ensure infrastructure remains secure, scalable, and aligned with company growth. What you will do Lead and refine Riverlane's IT strategy, policies, and roadmap to support company objectives and security needs. Manage and improve corporate IT systems, including endpoint management, identity and access management (IAM), collaboration tools, SaaS platforms, and networking. Direct IT procurement, oversee vendor relationships, and optimize software licensing across all platforms. Establish and maintain IT support processes to ensure high availability and responsiveness for a team of scientists and engineers. Develop and manage Riverlane’s information security framework, covering policies, risk management, access controls, and compliance with standards such as ISO 27001. Compensation Salary: £100,000 to £130,000 DOE