Director of Antibody Discovery

Join Flagship Pioneering Inc. as the Director of Antibody Discovery, where you will lead innovative initiatives in antibody research and development. This pivotal role involves overseeing a talented team, driving strategic projects, and collaborating with cross-functional teams to advance our cutting-edge therapeutic programs. Your expertise will be crucial in shaping the future of antibody therapeutics, fostering a culture of scientific excellence, and ensuring the successful execution of discovery projects.

Flagship Pioneering, Inc. is seeking a visionary and experienced Director of Antibody Discovery to lead our innovative research team in Cambridge, UK. In this pivotal role, you will be responsible for spearheading the development of novel antibody therapeutics that will define the future of medicine. You will leverage cutting-edge technologies and methodologies to drive our antibody discovery efforts, collaborating closely with cross-functional teams to bring groundbreaking solutions to patients.

Nuclera is an innovative venture-backed biotech company based in Cambridge, UK, with significant operations in Boston, USA. Our mission is to revolutionize the discovery process by providing rapid and straightforward access to functional proteins that are crucial for drug discovery research. Our cutting-edge eProtein Discovery™ benchtop system enhances the optimization of protein expression and purification in research laboratories.We are looking for a strategic and proactive Product Strategy Manager - Antibody Applications to lead the roadmap for antibody applications on our eProtein Discovery system. In this pivotal role, you will drive adoption among antibody discovery and reagent developers by effectively translating market demands into a distinctive product strategy, offerings, and go-to-market plans. As the antibody domain expert within our product organization, you will collaborate closely with R&D, commercial, and customer-facing teams to foster growth in this essential application area. You will be responsible for the overall success of the antibody applications segment, including defining the roadmap, assessing commercial performance, and developing lifecycle strategies.The ideal candidate will possess a deep background in antibody science paired with proven commercial experience, fully understanding the pain points, challenges, and opportunities in antibody discovery workflows. You should excel at transforming in-depth domain knowledge and customer feedback into compelling product strategies that enhance the adoption and success of Nuclera’s eProtein Discovery System.This role requires approximately 20% travel, including both domestic and international trips for customer meetings, industry events, and visits to Nuclera offices as needed.

Your Impact at Lila Sciences The Director of Discovery Chemistry will spearhead the design, synthesis, and optimization of small molecules across Lila’s discovery platform, emphasizing organic synthesis, molecular design, and scalable chemistry execution. This pivotal role will cultivate and expand a premier molecular chemistry program that translates AI-generated molecular hypotheses into high-quality, synthetically viable, and functionally validated chemical entities. Collaboration is key, as you will work closely with Lila’s AI, automation, computational biology, and platform teams to establish the chemistry infrastructure necessary to swiftly advance novel molecules from conception to validated candidates across diverse discovery initiatives. You will drive synthetic strategy, route design, analog generation, molecular property optimization, and chemistry-enabled innovation while ensuring seamless integration with robotic synthesis and platform-based experimentation. This leadership position is crucial in shaping Lila’s molecular discovery engine by leveraging deep expertise in synthetic organic chemistry, molecular design, and data-driven experimentation to expedite the discovery of high-value molecules for therapeutic and broader platform applications. What You Will Be Building Lead the discovery chemistry strategy across programs, focusing on small molecule design, synthetic innovation, analog generation, and optimization of chemical matter. Oversee the design and implementation of synthetic routes for novel small molecules, prioritizing speed, robustness, scalability, and compatibility with automated synthesis platforms. Develop and enhance efficient workflows for molecular design, compound prioritization, analog generation, and iterative design–make–test cycles in partnership with AI and computational teams. Collaborate closely with automation and platform teams to establish robotic and high-throughput chemistry capabilities that expand accessible chemical space and accelerate molecule generation. Guide the selection of reagents, reaction modalities, and synthetic methodologies to facilitate rapid exploration of structurally diverse and functionally relevant chemical entities.

Join Lila Sciences as a Senior Research Associate or Associate Scientist in the Protein Science department, focusing on our cutting-edge Antibody Platform. You will play a crucial role in advancing our research initiatives, contributing to the development of innovative antibody-based therapeutics. This position offers the opportunity to collaborate with a talented team dedicated to scientific excellence and the pursuit of transformative solutions in healthcare.

Join Eurofins Scientific as a Business Development Manager specializing in Drug Discovery. In this dynamic role, you will drive strategic initiatives to enhance our laboratory testing services, fostering collaboration with clients and stakeholders. You will leverage your expertise to identify market opportunities, develop client relationships, and contribute to the growth of our innovative drug discovery solutions.

Join our innovative team at Flagship Pioneering Inc., where we are at the forefront of therapeutic discovery. As a Senior Research Associate, you will play a critical role in advancing our understanding of novel therapeutic pathways and contribute to groundbreaking research in the life sciences.

Join AbbVie as a Senior Scientist II in our Assay Development team, focusing on innovative research in Discovery Psychiatry. This role involves designing, developing, and optimizing assays to advance our understanding of psychiatric disorders. You will collaborate with cross-functional teams to drive research initiatives and contribute to the discovery of effective treatments.The ideal candidate will possess strong scientific expertise, a passion for psychiatric research, and the ability to thrive in a dynamic environment.

Your Impact at Lila Sciences Lila Sciences is seeking a dynamic and visionary Director of Product, Life Sciences to lead our innovative product strategies. In this pivotal role, reporting directly to the Vice President of Life Science Product, you will be at the forefront of enhancing our therapeutic research and development capabilities, shaping the future of drug discovery, chemical synthesis, and scientific intelligence. What You'll Be Building Steer the strategic direction for developing breakthrough AI solutions in drug discovery, chemical synthesis, and molecular characterization. Convert strategic goals into comprehensive target product profiles (TPPs) and development campaigns that will empower our science and engineering teams to achieve groundbreaking innovations in life sciences. Lead customer and internal-user discovery initiatives, acting as the primary technical liaison between external customers and partners. Pinpoint and cultivate product opportunities driven by real-world discovery challenges, collaborating closely with stakeholders to ensure relevance and maximize downstream value. Transform insights into precise product requirements, acceptance criteria, and experimental plans that will guide our engineering and science teams. Oversee product execution from inception to launch, leading cross-functional teams across various disciplines including science, machine learning, automation, and software engineering. Manage resource allocations effectively (budget, compute, lab access, personnel) against a complex array of priorities. Establish clear success metrics and milestones, communicating progress to the organization, including executive leadership. What You'll Need to Succeed Advanced degree (MS, PhD, or equivalent experience) in medicinal chemistry, chemical biology, chemical engineering, biochemistry, or a related field, with a solid foundation in experimental science. 7+ years of experience in Product Management, particularly in developing new or experimental products in drug discovery, molecular profiling, machine learning, or scientific software development. In-depth understanding of drug development processes, molecular and cellular research tools, as well as wet and dry lab workflows. Experience with small molecule discovery workflows (e.g., lead optimization, ADMET profiling, synthesis planning) is highly preferred.

Your Role at Lila Sciences As a key contributor to our Physical Sciences division, you will focus on advancing the field of in silico materials discovery techniques. Your responsibilities will involve designing autonomous workflows and data-driven pipelines that effectively integrate simulation with artificial intelligence. You will lead the development of strategies that empower agents to analyze simulation data, derive hidden insights, and facilitate hypothesis generation and materials design. Your innovative approach will enhance our utilization of simulation outputs for discovery, fostering a seamless integration of physics-based modeling with AI reasoning systems. Collaboration with specialists in simulation, AI agents, and experimental automation will be pivotal as we strive to redefine the landscape of digital discovery. Key Contributions Create cutting-edge workflows for in silico materials discovery that link physics-based simulations and generative AI models. Develop intelligent systems where AI agents autonomously design, execute, interpret, and optimize simulations. Establish frameworks that maximize the utility of simulation data for prediction, inference, and discovery, with features like automatic data extraction and model training. Prototype and assess novel paradigms for simulation-aware agents that learn from and interact with scientific simulations. Design data structures, metadata specifications, and APIs to ensure smooth information transfer among simulations, machine learning models, and experimental data repositories. Build scalable, modular workflows that connect electronic structure, atomistic, and mesoscale simulations with AI-driven reasoning and hypothesis generation. Work alongside computational scientists, machine learning professionals, and platform engineers to integrate in silico discovery pipelines into Lila’s overarching scientific superintelligence framework. Qualifications for Success PhD or equivalent experience in Computer Science, Materials Science, Chemistry, Physics, Applied Mathematics, or related fields. Strong background in in silico materials discovery, computational materials modeling, and/or simulation workflow design. Familiarity with large language models and their applications in scientific research. Experience in developing AI-driven or agentic workflows for scientific automation and discovery. Proficient programming skills in Python and scientific computing libraries.

Your Impact at Lila The Senior Director of Small Molecule Therapeutics will spearhead the biological evaluation and screening of small molecule therapeutics within Lila’s innovative discovery platform. This pivotal leader will cultivate and expand a top-tier screening organization, effectively translating AI-designed and robotically synthesized molecules into validated biological insights and promising therapeutic opportunities. Collaborating closely with Lila’s chemistry, automation, and AI/computational teams, the Senior Director will establish the biological screening infrastructure necessary for the rapid evaluation of novel chemical entities. This role involves designing and implementing high-throughput and high-content screening strategies, constructing automated assay platforms, and developing creative methodologies to explore extensive chemical libraries. As a key architect of Lila’s small molecule discovery engine, this leader will integrate biology, automation, and data science into scalable discovery workflows, significantly accelerating the identification of high-quality therapeutic candidates. What You’ll Be Building Lead and develop Lila’s small molecule biology and screening organization, focusing on hiring, mentoring, and fostering a high-performing scientific team. Design and implement automated, high-throughput screening platforms to assess small molecules generated through Lila’s AI-driven chemistry and robotic synthesis systems. Develop and refine biochemical, biophysical, and cell-based assays for the identification and validation of novel small molecule hits. Establish scalable automation-enabled workflows for assay execution, screening campaigns, and data generation. Guide the development and execution of DNA-encoded library (DEL) screening strategies and subsequent validation pipelines. Work in partnership with chemistry, computational, and automation teams to harmonize screening results with molecular design and synthesis initiatives. Define and execute screening strategies targeting new therapeutic areas, including target validation, assay design, and hit identification. Oversee large-scale screening initiatives, including hit triage, orthogonal validation, and preliminary mechanism-of-action studies. Implement data-driven methodologies to analyze screening outputs and inform iterative molecule design processes. Set best practices for screening data quality, reproducibility, and assay robustness. Collaborate across various disciplines to translate screening hits into validated chemical starting points for therapeutic development. What You’ll Need to Succeed PhD in Molecular Biology, Biochemistry, or a related field.

Role Overview Isomorphic Labs is seeking a Director of Computational Drug Design to join its Cambridge, MA site. This leader will shape computational chemistry strategy for both internal research and collaborative projects. The position sits within the Drug Design and Medical Research division, working closely with AI and machine learning specialists to advance the company’s drug design engine and accelerate new medicine development. About Isomorphic Labs Founded in 2021, Isomorphic Labs (IsoLabs) builds on the AlphaFold system, applying advanced AI to solve complex problems in human health. The team combines drug discovery expertise with machine learning to create predictive and generative models that speed up scientific discovery. The company’s mission is to design novel molecules, predict drug performance, and develop new treatments for challenging diseases by modeling biological systems with AI. Isomorphic Labs has developed an AI-driven drug design engine capable across various therapeutic areas and drug types. The organization continues to refine model architectures and expand capabilities, aiming to realize the promise of digital biology and ultimately eradicate disease through artificial intelligence. About the Computational Drug Design Team The Cambridge-based Computational Drug Design team brings together computational chemists focused on driving strategy, supporting both internal and partner projects. Close collaboration with AI/ML colleagues is central to the group’s work, ensuring the continued evolution of the Isomorphic Labs Drug Design Engine. The team values a supportive environment, ongoing learning, and professional development for every member.

Scholar Rock is a pioneering biopharmaceutical company dedicated to discovering, developing, and delivering transformative therapies for patients with serious diseases that exhibit significant unmet needs. Renowned globally for our expertise in the biology of the transforming growth factor beta (TGFβ) superfamily, we are committed to advancing innovative treatments where protein growth factors are critical. Over the last decade, we have built a robust pipeline that has the potential to redefine the standard of care for neuromuscular diseases, cardiometabolic disorders, cancer, and various other conditions where growth factor-targeted therapies can make a significant impact.Scholar Rock uniquely demonstrated clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). Our dedication to exploring fundamentally different therapeutic avenues is driven by the innovative application of our proprietary platform, which has produced novel monoclonal antibodies that modulate protein growth factors with remarkable precision. By leveraging cutting-edge scientific research in disease areas historically underserved by conventional treatments, we work tirelessly to create new opportunities for patients. Discover more about our approach at ScholarRock.com and follow us on @ScholarRock and on LinkedIn.Position Overview:The Director or Senior Director of Regulatory Strategy, reporting directly to the Senior Vice President, Global Head of Regulatory Affairs, will be responsible for formulating and executing the global regulatory strategy for designated clinical and pipeline programs. As a subject matter expert, this individual will engage with program teams to identify regulatory risks and opportunities, thereby informing strategic direction and planning. The ideal candidate will spearhead interactions with regulatory authorities, overseeing the preparation and submission of all regulatory documentation and correspondence.

Join Flagship Pioneering Inc. as the Director/Senior Director of Compensation, where you will lead the strategic development and execution of our compensation programs. Your role will involve designing competitive compensation structures, ensuring alignment with industry standards, and driving initiatives that enhance employee engagement and performance. You will collaborate with senior leadership to shape compensation policies that reflect our commitment to attracting and retaining top talent.

Your Role at Lila Sciences Lila Sciences is seeking a proactive and strategic Director of Facilities to oversee the daily operations and long-term management of our diverse facilities. You will be responsible for developing a scalable facilities strategy, ensuring safety and compliance across all sites, and managing budgets, capital planning, vendor relationships, and KPI reporting. This role is a pivotal cross-functional leadership position, with the opportunity to build and nurture a world-class facilities team that aligns with our growth and supports our scientific mission. Your Key Contributions Strategic Leadership Develop and implement a comprehensive facilities strategy that aligns with company growth, scientific initiatives, and operational risk management. Recruit, mentor, and lead a high-performing facilities organization, fostering a culture of safety, reliability, and continuous improvement. Team Development Directly manage and mentor facility managers, supervisors, and support staff, promoting a collaborative culture focused on employee engagement and professional development. Encourage cross-functional collaboration with business development, technology, finance, legal, and HR teams to drive informed decisions and improvements. Safety and Compliance Establish and maintain enterprise-wide safety standards and compliance across all facilities; lead audits and implement corrective actions. Direct capital planning, lifecycle management, and end-of-life decisions for critical equipment using ROI-driven analyses. Financial Management Oversee multi-site budgets, long-term capital planning, and KPI performance; optimize total cost of ownership. Manage the vendor lifecycle, including RFPs, contract negotiations, service level agreements, and vendor performance evaluations. Operations Excellence Standardize and enhance maintenance processes utilizing documentation, digital tools, and scalable playbooks; champion improvements focused on employee and occupant satisfaction. Implement governance, risk management, and compliance controls to ensure audit readiness and transparent reporting. Stakeholder Engagement Act as the primary liaison with clients, senior leadership, the Facilities Organization, and key business teams, translating facilities strategy into measurable business value. Collaborate with HR on workforce planning, safety training, and related initiatives.

Join Iterative Health as our Director of Compliance, where you will play a pivotal role in shaping our compliance strategy and ensuring adherence to regulatory requirements. This leadership position will involve developing and implementing compliance programs, monitoring compliance performance, and liaising with regulatory bodies. You will lead a team of compliance professionals and collaborate with various departments to cultivate a culture of compliance within the organization.

Your Role at Lila Sciences Lila Sciences stands at the forefront of scientific innovation, operating as the world’s first scientific superintelligence platform and autonomous laboratory dedicated to life sciences, chemistry, and materials science. Our mission is to revolutionize the process of scientific discovery by seamlessly integrating AI into every facet of the scientific method, empowering researchers to address humanity’s most pressing challenges in health, climate change, and sustainability at unprecedented speed and scale. Position Overview As the Director/Senior Director of Applied AI, you will spearhead the establishment of our foundational Applied AI team, responsible for refining and adapting our AI models for practical product deployment. You will ensure their safe integration with diverse customer datasets and oversee the development of high-performance interfaces, including chat experiences and inference endpoints like gRPC, HTTP, and PCP servers. Reporting directly to the CTO, you will manage the complete roadmap from data acquisition to model deployment, collaborating closely with Research, Product, Software, Application, Safety, and Security teams to deliver models that are functional, quantifiable, and dependable. Key Responsibilities Lead and mentor a high-performing Applied AI team to produce exceptional scientific reasoning models for consumer applications. Manage an end-to-end model customization pipeline to generate impactful models from Lila’s base models for high-value applications, including inference, chat, and API integration. Develop a comprehensive evaluation framework to facilitate ongoing model enhancement and performance optimization. Collaborate with cross-functional teams to define project requirements, deliver customer proofs of concept (POCs), and transition successful pilots into scalable products. Establish technical standards, documentation, and incident response protocols for AI systems in production. Recruit, mentor, and foster a diverse and inclusive team environment. Qualifications for Success 8+ years of experience in applied machine learning or ML systems, with a minimum of 3 years in a leadership role; proven track record of deploying large language models (LLMs) into production. Extensive experience in fine-tuning and evaluating large-scale models for customer interactions. Production inference expertise, including familiarity with serving frameworks (Triton, vLLM, TGI, Ray, Kubernetes), GPU orchestration, caching, and observability. Strong understanding of data privacy and security best practices in multi-tenant systems. Preferred Qualifications Experience with instruction fine-tuning and optimization techniques. Proficiency in developing chat user experiences, implementing guardrails, tool/function calling, and managing long-context interactions.

About Flagship Pioneering, Inc. Flagship Pioneering is at the forefront of innovation, dedicated to inventing and nurturing platform companies that have the potential to revolutionize human health, sustainability, and more. Since our inception in 2000, we have successfully launched over 100 companies that tackle some of the world's most pressing challenges, such as vaccinating billions against COVID-19, curing difficult diseases, enhancing human health, preventing illness, and improving agricultural resilience and sustainability. Our commitment to impactful innovation has earned us recognition on FORTUNE's 'Change the World' list, highlighting companies that make a significant social and environmental impact, and we have appeared on Fast Company's annual list of the World’s Most Innovative Companies. Position Summary: We are looking for a passionate and experienced individual to join our Communications and Public Affairs team as the Senior Director of Communications. In this role, you will spearhead the development and implementation of communications and branding strategies for a selection of companies within Flagship Pioneering's diverse portfolio. The ideal candidate will possess a robust background in biotech corporate communications and excel in a fast-paced, startup atmosphere. This is a remarkable opportunity to influence the trajectory of groundbreaking life sciences and technology firms across human health, agriculture, and AI sectors. This full-time role requires in-office presence four days a week in Cambridge, MA. Key Responsibilities: Provide strategic counsel to the founders and leadership of emergent Flagship companies (Flagship NewCos) in developing their brand, voice, foundational messaging, and overall communication strategies. Oversee brand development, visual identity, and website design for NewCos, collaborating with external agencies. Create and implement tailored, integrated communication strategies for company launches, encompassing all written content, media engagement, and social media components. Manage PR agency support as necessary. Develop and execute communication strategies for both NewCos and more established companies (Flagship GrowthCos), including milestone announcements, internal communications, social and digital media strategies, speaking opportunities, and issue management, in close collaboration with company leadership.

Scholar Rock is a pioneering biopharmaceutical entity dedicated to the discovery, development, and delivery of transformative therapies aimed at addressing significant unmet medical needs. As a recognized leader in the biology of the transforming growth factor beta (TGFβ) superfamily, and inspired by the structural resemblance of a scholar rock to protein formations, our clinical-stage company is devoted to advancing groundbreaking treatments that leverage protein growth factors. Over the last decade, we have established a robust pipeline designed to redefine the standard of care for conditions such as neuromuscular diseases, cardiometabolic disorders, and cancer, where growth factor-targeted therapies can make a substantial impact. Scholar Rock stands out as the sole organization demonstrating clinical proof of concept for a muscle-targeted therapy in spinal muscular atrophy (SMA). Our commitment to unlocking innovative therapeutic pathways is underscored by the extensive application of our proprietary platform, which has yielded novel monoclonal antibodies to selectively modulate protein growth factors. By harnessing cutting-edge scientific advancements in traditionally underserved disease areas, we strive each day to create new possibilities for patients. Discover more about our mission at ScholarRock.com and connect with us on @ScholarRock and LinkedIn.Position Overview:As Scholar Rock embarks on a pivotal phase with the impending launch of our inaugural commercial product, we are in search of a strategic and operationally-savvy Senior Director of Global Facilities. This role transcends purely administrative functions; we require a visionary builder who comprehends the intricacies of scaling infrastructure within a rapidly evolving biotech setting while adeptly navigating day-to-day operational challenges.With facilities strategically located worldwide and poised for future growth, you will be responsible for ensuring our environments are safe, compliant, efficient, and conducive to supporting both research and commercial initiatives. If you are a proactive self-starter who thrives in dynamic, transformative organizations and is eager to contribute significantly, this opportunity allows you to apply your expertise, learn extensively, and make a meaningful impact.

The Opportunity: Join Relay Therapeutics as a Senior Medical Director, where you will be pivotal in propelling our clinical pipeline from IND to proof of concept and ultimately to registration. In this role, you will partner with senior medical staff to shape clinical strategies, design clinical trials, and ensure successful execution. Collaborating across various functions including clinical project management, regulatory affairs, clinical operations, biostatistics, data management, and medical writing, you will significantly contribute as Relay Therapeutics continues to advance product candidates into clinical settings. You will provide clinical leadership to R&D teams and closely collaborate with Development leadership. We are open to remote employees