Senior Scientist/Principal Scientist, Biologics Cell Line Development

Asimov is seeking a highly skilled and experienced Senior Scientist/Principal Scientist in Biologics Cell Line Development to join our innovative team in Boston, MA. In this pivotal role, you will lead the development of high-yield mammalian cell lines for the production of biologics. You will collaborate closely with cross-functional teams to optimize production processes and ensure the successful translation of cell line development from research to clinical applications.

Asimov builds tools for designing living systems, combining mammalian synthetic biology with software to support next-generation therapeutics. The Biologics Cell Line Development team in Boston, MA, is growing, and we're seeking a Principal Scientist to help lead our efforts in CHO-based cell line development for biologic therapeutics moving into clinical trials. Role Overview This Principal Scientist position calls for a scientific leader ready to manage a team and drive innovation in cell line development. The role involves designing and executing complex experiments, improving expression systems, and collaborating closely with teams across synthetic biology, modeling, process development, and analytics. The work directly supports Asimov’s mission to advance biological engineering in a startup environment. What You Will Do Oversee CHO cell line development, including transfection, cloning, characterization, and cell banking using advanced technologies. Develop new genetic components, engineer host cell lines, and refine development processes to improve biologics production. Stay current with emerging practices in biologics cell line development and manufacturing, applying new strategies to ongoing projects. Represent the cell line development group on cross-functional projects, making key decisions and communicating progress and plans. Contribute to the scientific community by presenting at conferences, filing patents, and publishing peer-reviewed research. Lead and mentor a team of at least three scientists, providing technical guidance and supporting their career growth. Qualifications At least 8 years of experience in CHO-based cell line development, with a focus on IgG and bispecific expression in an industrial setting. Demonstrated success in creating innovative solutions and experimental approaches in cell line development. Experience managing and developing scientific teams. Strong communication skills for effective work across multidisciplinary groups.

Axon Enterprise, Inc. develops devices and cloud-based software focused on public safety and justice. The company’s teams value collaboration, open communication, and diversity, aiming to create meaningful change while supporting employee growth and ownership. Role overview The Principal Data Scientist will join the Office of the Chief Accounting Officer in Boston. This position blends technical expertise with a strong understanding of finance and accounting. The main goal is to ensure Axon’s AI developers, process owners, decision-makers, and auditors have access to reliable, well-governed data that meets audit requirements. Main responsibilities Design and build data analytics tools and pipelines, dedicating about half of the workload to hands-on development. Apply AI to advance projects such as M&A integration, ERP rollouts, upstream data remediation, and SOX compliance. Work closely with teams in Controllership, Finance Operations, FP&A, Internal Audit, and Technology to support AI, automation, and audit readiness. Incorporate AI-driven development tools into daily tasks to improve productivity and outcomes. Location This position is based in Boston, Massachusetts, United States.

About Cellular IntelligenceCellular Intelligence, previously known as Somite AI, is an innovative venture-backed firm striving to redefine the realm of stem cell biology. We are on a mission to develop AI foundation models that will revolutionize human stem cell applications and promote scalable novel cell therapies.Our comprehensive approach involves generating data at unprecedentedly low costs, training large-scale models with unparalleled predictive capabilities, and employing these models to discover, refine, and optimize impactful applications in cell therapy.Our exceptional founding team includes seasoned AI entrepreneur Dr. Micha Breakstone (Chorus.ai, acquired for $575M), the Head of the Fundamental AI Group at MIT, who has pioneered foundational research on scaling laws, alongside three esteemed Harvard Medical School professors and members of the National Academy of Sciences/Medicine, including the Chair of the Genetics Department at HMS. Based in Boston and set to commence operations in January 2024, Cellular Intelligence has successfully raised nearly $60M to date.Core Values of Cellular Intelligence:Accountability: We show up fully, taking responsibility and committing to our goals.Urgency: We act swiftly and decisively, maintaining a proactive approach.Collaboration: We support one another with empathy and teamwork.Location: Boston, MA (onsite, full-time)About the Role:In the capacity of Senior Computational Biologist, you will be instrumental in developing pipelines, models, and conducting research on extensive single-cell datasets. This role is tailored for individuals passionate about large-scale transcriptomic data that will contribute to pioneering cell replacement technologies. You will operate at the intersection of developmental biological research, data science, and software development, aiding in single-cell and spatial transcriptomics analysis while translating scientific breakthroughs into advanced cell replacement therapies.

CarGurus, a leading online automotive marketplace, is seeking a Principal Data Scientist to join our innovative team in Boston, Massachusetts. As a Principal Data Scientist, you will leverage your expertise in data analysis, machine learning, and statistical modeling to drive insights that enhance our product offerings and improve user experiences. You will play a crucial role in shaping our data strategy and leading complex projects that impact the entire organization.

Join Formation Bio as a Principal Data Scientist, where you will play a pivotal role in shaping our data-driven strategies. We are seeking a highly skilled and innovative data scientist to lead complex projects and drive actionable insights from our data.In this position, you will collaborate with cross-functional teams, leveraging your expertise in statistical analysis, machine learning, and data visualization to inform decision-making and improve our products. Your contributions will directly impact our mission to harness data for groundbreaking advancements in biotechnology.

Cellular Intelligence (CI) is a pioneering AI-driven TechBio firm dedicated to constructing a universal foundation model of cell signaling. Our goal is to comprehend, forecast, and ultimately manipulate cellular behavior, thereby revolutionizing biology from a trial-and-error approach into a precise engineering discipline. With a full-stack methodology, we produce perturbation data at over 1,000 times the efficacy of traditional methods, capturing millions of time-resolved treatment combinations in each experiment. Our large-scale models are designed to generalize across various contexts, facilitating rational protocol design for regenerative medicine, specific drug effect prediction, and systematic disease modeling. The founding team includes notable AI entrepreneur Dr. Micha Breakstone, former Head of the Fundamental AI Group at MIT, and four esteemed professors from Harvard Medical School and the University of Washington, including the Chair of Genetics at Harvard, collectively holding five National Academy memberships. Based in Boston, CI has successfully raised over $60 million from investors such as Khosla Ventures, CZI, SciFi VC, and AMD Ventures, and is rapidly expanding its exceptional team.Core Values of Cellular IntelligenceAccountability - We show up fully accountable, committed, and ready to do whatever it takes.Urgency - We act swiftly, decisively, and proactively.Collaboration - We support each other through teamwork, helpfulness, and empathy.

We are seeking a passionate and detail-oriented Associate Scientist / Bench Scientist to join our dynamic team in Boston. In this role, you will be responsible for conducting experiments, analyzing data, and contributing to innovative research projects that advance our scientific knowledge and product development.

COMPANY DESCRIPTION Abiologics, Inc. is an innovative, privately held biotechnology company dedicated to transforming biology through advanced therapeutic modalities. We are leading the charge in developing Synteins™, a groundbreaking class of macromolecular medicines propelled by cutting-edge synthetic and computational technologies. We are on the lookout for outstanding scientists who are fervent about pioneering therapeutic modality innovations within the biotechnology landscape. Founded within Flagship Pioneering’s venture creation engine, Abiologics has its roots alongside remarkable companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines. Since its inception in 2000, Flagship has nurtured over 100 scientific ventures, producing more than 500 patents and facilitating over 50 clinical trials for novel therapeutic agents. THE ROLE We invite applications for an experienced and driven Senior Scientist in Medicinal Chemistry, with a specialization in miniprotein and peptide drugs. The ideal candidate will be instrumental in the design, synthesis, and optimization of innovative miniprotein therapeutics known as Synteins™. This role provides a distinctive opportunity to guide a new drug modality from early-stage research all the way through clinical development. KEY RESPONSIBILITIES Independently plan, execute, interpret, and enhance Syntein structure-activity campaigns through hands-on laboratory engagement. Utilize modern peptide chemistry and conjugation techniques to expedite the optimization of miniprotein drug development. Collaborate with interdisciplinary teams, including computational chemistry, biology, and pharmacology, to ensure project success. Champion innovation at the bench-side, ensuring a seamless transition from concept to execution. Mentor and lead junior scientists, promoting a collaborative and dynamic laboratory environment. Contribute to patent applications and scientific publications, highlighting laboratory advancements.

ABOUT ABIOLIGICS Abiologics, Inc. is a dynamic, privately held biotechnology firm committed to enhancing biological processes via innovative therapeutic modalities. We are at the forefront of developing Synteins™, a groundbreaking class of macromolecular medicines that leverage cutting-edge synthetic and computational technologies. We are in search of talented scientists eager to advance therapeutic modality innovation within the biotechnology sector. Founded within Flagship Pioneering’s venture creation engine, Abiologics benefits from a legacy of innovation that has birthed industry leaders like Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines. Since 2000, our parent company has been instrumental in launching over 100 scientific ventures, resulting in 500+ patents and 50+ clinical trials for novel therapeutic agents. ROLE OVERVIEW We are looking for a highly skilled and driven Senior Scientist in Medicinal Chemistry with a specialization in miniprotein and peptide drugs. The successful candidate will spearhead projects focused on the design, synthesis, and optimization of innovative miniprotein therapeutics known as Synteins™. This position offers a unique chance to advance a new drug modality from initial research stages into clinical development. KEY RESPONSIBILITIES Plan, execute, interpret, and optimize Syntein structure-activity campaigns through hands-on laboratory work. Utilize modern peptide chemistry and conjugation methods to enhance the development of miniprotein drugs. Collaborate with interdisciplinary teams, including computational chemistry, biology, and pharmacology, to ensure project success. Foster innovation at the bench side, facilitating the transition of concepts into practical applications. Mentor and support junior scientists, creating a collaborative and vibrant lab environment. Contribute to patent applications and scientific publications, highlighting laboratory innovations.

Join Cellular Intelligence as a Senior/Principal Machine Learning Researcher!At Cellular Intelligence, formerly known as Somite AI, we strive to revolutionize stem cell biology by creating AI foundational models that facilitate the development of innovative cell therapies on a large scale.Our comprehensive approach allows us to generate data at a cost efficiency of 1,000 times lower than traditional methods, while training large-scale models that possess unparalleled predictive capabilities. These models are pivotal in discovering, refining, and optimizing impactful applications in cell therapy.Our founding team boasts a wealth of experience, including AI entrepreneur Dr. Micha Breakstone, who successfully led Chorus.ai to a $575M acquisition, the Head of MIT's Fundamental AI Group, and a cadre of professors from Harvard Medical School and the University of Washington, comprising members of the National Academy of Sciences and Medicine. Based in Boston, we are excited to commence operations in January 2024 and have secured nearly $60 million in funding to date.

At IonQ, we are pioneering the development of the world's most advanced full-stack quantum computer utilizing trapped-ion technology. Our mission is to transcend the limitations of classical physics and current supercomputing capabilities, ushering in a transformative era of computing. The potential of quantum computing to enhance every aspect of human life is immense, and IonQ's innovations are set to revolutionize fields including medicine, materials science, finance, artificial intelligence, machine learning, cryptography, and beyond. Join us at the forefront of this technological evolution.We are seeking a Senior Research Scientist specializing in quantum memory development. In this pivotal role, you will spearhead a cross-functional team dedicated to advancing IonQ's mission to construct the preeminent quantum computers capable of tackling the world's most intricate challenges.Your work will involve groundbreaking research in quantum memories tailored for extensive quantum networks and modular quantum computing architectures. Collaborating with a prestigious team of scientists and engineers, you will develop systems designed for rapid processing and storage of quantum information derived from photons, ultimately leading to the creation of scalable quantum computing solutions. Your contributions will range from innovative system design to operationalizing and expanding quantum memory systems that will serve as the foundation for the largest quantum computers globally.

Join Formlabs as a Materials Scientist specializing in photopolymer development, where you will play a critical role in advancing our innovative 3D printing technology. You will be responsible for researching, developing, and optimizing photopolymer materials to enhance product performance and application versatility. Collaborate with cross-functional teams to translate material science insights into practical solutions that drive product excellence.

The Single Cell Core (SCC) at Harvard Medical School is on the lookout for a Research Core Scientist to enhance our team. The ideal candidate will partner closely with the SCC Director to master single-cell RNA-sequencing and spatial transcriptomics techniques. This role involves executing experiments, working collaboratively with researchers to maximize the utility of valuable data derived from rare samples, and optimizing and validating novel technologies across a diverse range of genomics workflows. We seek an innovative, detail-oriented individual with strong analytical skills and exceptional communication abilities, capable of presenting findings in group lab meetings and regional scientific conferences. This position offers a unique opportunity to engage with cutting-edge methodologies at the forefront of next-generation sequencing and spatial transcriptomics, while also providing valuable experience in project management and leadership.Key Responsibilities:Independently conduct intricate single-cell and spatial transcriptomics experiments using various technologies. Manage library preparation and quality control processes. Regularly update and report on experimental progress to users, collaborating with the Director to troubleshoot errors and enhance workflows.Work alongside researchers to design and implement complex experiments utilizing rare samples. As a leading expert in single-cell and spatial transcriptomics at HMS, assist in validating and refining experimental protocols to establish efficient custom workflows, while offering expertise during data analysis and interpretation.Provide training to faculty, trainees, and other staff members on single-cell and spatial transcriptomics instrumentation.Organize and lead promotional and outreach initiatives, including workshops and user group meetings.Oversee core maintenance tasks, including supply procurement, equipment upkeep, and database management. Perform additional duties as necessary, such as billing and administrative tasks.Physical Requirements: Must be able to lift up to 25 lbs.

Join Formlabs as a Senior Materials Scientist and play a crucial role in advancing our innovative 3D printing technologies. You will be instrumental in developing new materials and enhancing existing formulations to meet the diverse needs of our users. Collaborate with cross-functional teams to drive product development and ensure the highest standards of quality. Your expertise will help shape the future of additive manufacturing.

IonQ is looking for a Senior Research Scientist with expertise in Fabrication to help drive progress in quantum computing hardware. This position is based in Boston, Massachusetts. Role overview This role centers on leading research projects focused on developing new fabrication methods for quantum hardware. The Senior Research Scientist will work closely with colleagues from various disciplines to design, test, and refine fabrication processes that improve the performance and reliability of IonQ’s quantum systems. What you will do Lead research initiatives to create and advance fabrication techniques for quantum computing hardware Collaborate with cross-functional teams to design, implement, and optimize fabrication processes Contribute to the enhancement of IonQ’s quantum hardware capabilities through innovative research Requirements Strong background in fabrication, ideally with experience relevant to quantum hardware Ability to lead research projects and work effectively with multidisciplinary teams Motivation to develop and improve fabrication processes for advanced technology

Join Eurofins as a Biophysical Analytical Scientist, where you'll contribute to groundbreaking scientific research and development. In this role, you will utilize state-of-the-art biophysical techniques to analyze and characterize biomolecules. Your expertise will be vital in ensuring the quality and efficacy of products across various sectors.

About AbiologicsAbiologics is a pioneering company under Flagship Pioneering, dedicated to innovating in the field of synthetic biology through the development of Synteins™—a revolutionary category of fully synthetic proteins crafted from entirely artificial building blocks, including D-amino acids and non-canonical residues. Synteins are engineered to overcome the constraints of conventional biologics, offering enhanced oral stability, immune evasion, and metabolic durability, all while being fully programmable by design.Utilizing a cutting-edge AI-enabled discovery platform, Abiologics merges generative design, automated synthesis, and rapid experimental screening to facilitate iterative optimization at scale.

IonQ is at the forefront of quantum computing, pioneering the development of the world's most advanced full-stack quantum computer using trapped-ion technology. Our work transcends the boundaries of classical physics and supercomputing, ushering in a transformative era for computing. Quantum computing holds the promise of significantly enhancing various sectors, including medicine, materials science, finance, artificial intelligence, machine learning, cryptography, and beyond. Join us as we redefine industries with our cutting-edge quantum solutions.We are seeking a talented and driven Lead Microwave Research Scientist to join our dynamic team. In this role, you will collaborate with a multidisciplinary team dedicated to advancing IonQ's mission of constructing the most effective quantum computers capable of addressing the globe's most intricate challenges.As a Lead Microwave Research Scientist, you will be responsible for:Collaborating with architecture teams to translate system-level specifications into detailed component-level requirements and design guidelines.Designing microwave circuits while considering performance targets, fabrication capabilities, and interactions with other components.Fabricating and testing prototype devices.Managing partnerships with external vendors to enhance fabrication and testing processes at scale.Working alongside internal testing and measurement teams to verify that devices fulfill specified performance criteria.

About Formation BioFormation Bio is a pioneering technology and AI-driven pharmaceutical company, uniquely positioned to enhance the efficiency of drug development. With the rapid advancements in AI and drug discovery, the industry is faced with a growing number of candidate drugs that are often stalled due to the prohibitive costs and lengthy timelines associated with clinical trials. Understanding that this bottleneck can restrict the availability of new medicines to patients, Formation Bio, established in 2016 as TrialSpark Inc., has developed advanced technology platforms and processes that effectively accelerate all phases of drug development and clinical trials. Our approach involves partnering with, acquiring, or in-licensing drugs from pharmaceutical companies, research organizations, and biotechnology firms to advance programs beyond clinical proof of concept, ultimately expediting the delivery of new treatments to patients. Our company is backed by a diverse group of influential investors from both the pharmaceutical and technology sectors, including a16z, Sequoia, Sanofi, Thrive Capital, Sam Altman, John Doerr, Spark Capital, SV Angel Growth, and others. Explore more about us through the following links:Our Vision for AI in PharmaOur Current Drug PortfolioOur Technology & PlatformAt Formation Bio, our core values drive our mission to transform the pharmaceutical industry. Each team member embodies these values, playing a crucial role in our commitment to delivering new treatments to patients with greater speed and efficiency. About the PositionAs a Senior Data Scientist specializing in Medical Imaging at Formation Bio, you will spearhead our initiatives to incorporate cutting-edge imaging analytics and AI into our drug development processes. In this pivotal role, you will explore the application of computer vision and deep learning techniques on medical imaging data (including MRI, X-ray, CT, and PET) to expedite clinical trials and enhance patient outcomes. You will be responsible for developing state-of-the-art models for automated image analysis, monitoring disease progression, and assessing treatment responses. Collaborating closely with clinical teams, radiologists, and drug development specialists, you will translate complex imaging data into actionable insights that inform critical decisions across our portfolio. This role provides a unique opportunity to redefine the integration of medical imaging within pharmaceutical development.