Clinical Operations Lead

We are seeking an experienced and innovative Device Development Lead to spearhead our efforts in advancing Drug Delivery Systems. The ideal candidate will possess a deep understanding of device development, coupled with a passion for enhancing patient outcomes through cutting-edge technology.Your role will involve leading cross-functional teams, driving product design, and ensuring compliance with regulatory standards. You will also be responsible for conducting feasibility studies, prototyping, and overseeing the entire development lifecycle from concept to clinical trials.

Join Eurofins Scientific as a Business Development Manager specializing in Drug Discovery. In this dynamic role, you will drive strategic initiatives to enhance our laboratory testing services, fostering collaboration with clients and stakeholders. You will leverage your expertise to identify market opportunities, develop client relationships, and contribute to the growth of our innovative drug discovery solutions.

Role overview Lila Sciences seeks a Scientist I/II in Drug Delivery Chemistry for its Cambridge, MA location. This role centers on advancing drug delivery systems that align with the company’s broader research objectives. Key responsibilities Collaborate with fellow researchers to design and refine drug delivery technologies. Apply chemistry expertise to enhance scientific strategies and laboratory processes. Contribute to projects focused on improving patient outcomes through innovative drug delivery solutions. Location This position is based in Cambridge, Massachusetts.

Role Overview Isomorphic Labs is seeking a Director of Computational Drug Design to join its Cambridge, MA site. This leader will shape computational chemistry strategy for both internal research and collaborative projects. The position sits within the Drug Design and Medical Research division, working closely with AI and machine learning specialists to advance the company’s drug design engine and accelerate new medicine development. About Isomorphic Labs Founded in 2021, Isomorphic Labs (IsoLabs) builds on the AlphaFold system, applying advanced AI to solve complex problems in human health. The team combines drug discovery expertise with machine learning to create predictive and generative models that speed up scientific discovery. The company’s mission is to design novel molecules, predict drug performance, and develop new treatments for challenging diseases by modeling biological systems with AI. Isomorphic Labs has developed an AI-driven drug design engine capable across various therapeutic areas and drug types. The organization continues to refine model architectures and expand capabilities, aiming to realize the promise of digital biology and ultimately eradicate disease through artificial intelligence. About the Computational Drug Design Team The Cambridge-based Computational Drug Design team brings together computational chemists focused on driving strategy, supporting both internal and partner projects. Close collaboration with AI/ML colleagues is central to the group’s work, ensuring the continued evolution of the Isomorphic Labs Drug Design Engine. The team values a supportive environment, ongoing learning, and professional development for every member.

As a Drug Safety Associate at Integrated Resources Inc., you will play a crucial role in ensuring the safety and efficacy of pharmaceutical products. You will be responsible for monitoring and evaluating adverse events, coordinating safety reports, and contributing to the overall pharmacovigilance efforts within our organization. Your attention to detail and analytical skills will be vital in supporting our commitment to patient safety.

Join Isomorphic Labs as the Head of Chemistry in Drug Design, where you will be at the forefront of innovative drug discovery. You will lead a talented team of chemists, collaborating with interdisciplinary groups to design and optimize drug candidates. Your expertise will guide the development of cutting-edge pharmaceutical solutions that have the potential to transform patient outcomes.

Join Integrated Resources Inc. as a Senior Drug Safety Associate and contribute to the vital field of drug safety and pharmacovigilance. In this role, you will play a key part in monitoring and ensuring the safety of pharmaceutical products, working closely with cross-functional teams to assess risk and implement safety measures.

Scholar Rock, Inc. is a pioneering biopharmaceutical firm dedicated to the discovery, development, and delivery of transformative therapies for individuals suffering from serious diseases with significant unmet medical needs. As a recognized leader in the biology of the transforming growth factor beta (TGFβ) superfamily of proteins, Scholar Rock is committed to advancing innovative treatments where the modulation of protein growth factors is crucial. Over the last decade, we have developed a robust pipeline aimed at redefining the standard of care for neuromuscular conditions, cardiometabolic disorders, cancer, and other diseases where growth factor-targeted therapies can radically change patient outcomes. Scholar Rock is the first and only company to demonstrate clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). Our commitment to unlocking unique therapeutic strategies is driven by our proprietary platform, which has generated novel monoclonal antibodies designed to modulate protein growth factors with remarkable precision. By leveraging cutting-edge scientific advancements in therapeutic areas that have historically been overlooked by conventional treatments, Scholar Rock tirelessly works to create new avenues for patient care. Discover more about our innovative approach at ScholarRock.com and follow us on @ScholarRock and LinkedIn.Position Overview:The Senior Medical Director of Drug Safety & Pharmacovigilance plays a critical role within the company, significantly influencing the development and lifecycle management of drug projects. This position is responsible for defining and implementing safety strategies and providing expert guidance during both pre- and post-approval phases for assigned products. The Senior Medical Director will proactively lead risk management initiatives in compliance with global regulatory standards, continuously evaluating safety data, conducting signal detection, and managing the safety profiles of compounds. Additionally, this role will involve close collaboration with cross-functional teams to achieve project objectives within established timelines and quality standards.

We are seeking a highly skilled Associate Director of Drug Safety and Pharmacovigilance to join our dynamic team at Nuvalent. This pivotal role involves overseeing drug safety operations, ensuring compliance with regulatory requirements, and enhancing the pharmacovigilance strategy. The ideal candidate will possess a deep understanding of drug safety processes and a passion for advancing patient safety in the pharmaceutical industry.

Isomorphic Labs is hiring a Head of Translational Sciences, Drug Design for its Cambridge, MA site. This senior leader will guide the translational strategy across the drug discovery portfolio, working closely with teams at the intersection of biology, artificial intelligence, and medicine. The position plays a central role in shaping how new therapies are advanced and how disease mechanisms are understood within the organization. Role overview This leadership role focuses on driving translational approaches for drug design. The Head of Translational Sciences will collaborate with colleagues to advance projects from early discovery through clinical evaluation. The team’s work includes strengthening biological insights into disease, supporting the selection of drug targets, and developing biomarkers to track pharmacodynamic effects and target engagement in clinical studies. Translational Sciences at Isomorphic Labs The Translational Sciences group in Boston is essential to the company’s mission. This team informs critical decisions across the portfolio, guiding projects through various stages of research and development. Close collaboration with other teams ensures that scientific progress benefits from both biological expertise and AI-driven insights. Company background Founded in 2021, Isomorphic Labs (IsoLabs) builds on the breakthroughs of the AlphaFold system. The company brings together drug discovery experts and machine learning specialists to develop predictive and generative AI models that accelerate scientific progress. The team uses AI to model complex biological systems, design new therapeutic molecules, and pursue treatments for challenging diseases. Ongoing innovation in model architecture supports work across diverse therapeutic areas and modalities. Culture Isomorphic Labs values interdisciplinary collaboration and a supportive environment. Every team member contributes to the shared goal of addressing serious diseases through AI-driven science and digital biology.

Scholar Rock is a pioneering biopharmaceutical organization dedicated to the discovery, development, and provision of transformative therapies aimed at addressing significant unmet medical needs for individuals suffering from serious health conditions. As a frontrunner in understanding the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins, our clinical-stage company is devoted to advancing innovative treatments that leverage the fundamental role of protein growth factors. Over the last decade, we have established a robust pipeline that aims to elevate the standard of care for conditions such as neuromuscular diseases, cardiometabolic disorders, cancer, and other illnesses where growth factor-targeted therapies can make a substantial difference. Scholar Rock is distinctively positioned as the only company to showcase clinical proof of concept for a muscle-targeted therapy in spinal muscular atrophy (SMA). Our unwavering commitment to exploring fundamentally novel therapeutic strategies is fueled by our proprietary platform, which has successfully developed innovative monoclonal antibodies designed to modulate protein growth factors with remarkable selectivity. By applying cutting-edge scientific advancements in traditionally under-addressed disease areas, we strive daily to forge new possibilities for patients. Discover more about our approach at ScholarRock.com and follow us on @ScholarRock and LinkedIn.Position Overview:Scholar Rock is actively seeking a highly skilled and technically adept Senior Director of Drug Product External Manufacturing to spearhead the external manufacturing of drug products across our portfolio of biologics, which includes monoclonal antibodies, fusion proteins, and bispecifics. In this pivotal role, you will lead and supervise all drug product manufacturing operations conducted through external contract manufacturing organizations (CMOs). This position is essential for ensuring the efficient production, quality assurance, and timely delivery of both clinical and commercial products, in alignment with our organizational objectives and stringent regulatory requirements. The ideal candidate will possess extensive expertise in biopharmaceutical manufacturing, demonstrate strategic leadership capabilities, and exhibit a strong aptitude for managing complex global operations.

Nuvalent is seeking a highly experienced and visionary Senior Director of Drug Metabolism and Pharmacokinetics (DMPK) to lead our DMPK team. This role is crucial for the advancement of our drug development programs as we strive to create innovative treatments. Join us in our mission to transform the lives of patients with targeted therapies.

Your Impact at Lila Lila Sciences is actively seeking a talented Boomi Developer to spearhead the design, development, and maintenance of integrations that enhance our core business systems. In this role, you will oversee the complete integration delivery process within Boomi AtomSphere—from gathering requirements and mapping to deployment, monitoring, and ongoing support. You will collaborate closely with stakeholders in Finance, People Ops, IT, and GTM. Familiarity with procure-to-pay (P2P) and onboarding/offboarding workflows is highly valued. What You Will Build Design, develop, and maintain Boomi AtomSphere integrations, including processes/atoms, APIs, schedules, connectors across various platforms such as ERP, HCM, IAM, CRM, ITSM, and data. Convert business needs into scalable integration designs and data mappings (JSON, XML, CSV, EDI). Create robust error handling, retries, and alert systems; ensure observability and maintain clear runbooks for L1/L2/L3 support. Administer Boomi MDH to uphold Data Quality and Source Data integrity. Execute and manage REST/SOAP APIs, webhooks, and event-driven patterns as necessary. Enhance existing integrations for performance, reliability, and cost-effectiveness; safely phase out outdated jobs. Oversee CI/CD, environment promotion, and release governance for integration assets. Guarantee data quality, security, and compliance (PII handling, least privilege, audit readiness). Collaborate with stakeholders to prioritize the roadmap; provide estimates, status updates, and documentation. Offer production support within defined SLAs, including incident response and root-cause analysis. Contribute to standards, templates, and best practices for integration development at Lila. What You’ll Need to Succeed 3–5 years of experience in integrations/iPaaS, with a minimum of 2 years of hands-on experience with Boomi AtomSphere. Expertise in API design and integration (REST/SOAP), authentication methods (OAuth2, JWT, API keys), and data formats (JSON, XML, CSV). Strong data transformation abilities (map functions, scripting, XSLT preferred) and familiarity with error-handling patterns. Proficient understanding of data quality, security, and compliance standards. Ability to communicate effectively with technical and non-technical stakeholders. A proactive approach to problem-solving and a commitment to continuous improvement.

Join our innovative team as a Systems Software Architect at ttp1 in Cambridge. In this role, you will be pivotal in designing, developing, and implementing advanced software solutions that drive our deep tech initiatives. We’re looking for a visionary who can blend technical expertise with strategic insight to create systems that are not only functional but also scalable and robust.Your responsibilities will include collaborating with cross-functional teams, conducting system architecture assessments, and ensuring software meets both technical and user requirements. If you are passionate about technology and eager to work in a dynamic environment, we want to hear from you!

Redgate Software develops tools that help data professionals manage and protect critical databases. As organizations face growing data needs, evolving regulations, and new technologies, Redgate’s products play a key role in supporting these changes. The Shared Applications & Services team oversees the business systems and data flows that underpin daily operations. This group addresses complex technical problems and values collaborative decision-making, drawing on input from across the team to shape its direction. Role overview The Business Systems Architect leads the design and structure of Redgate’s internal systems. This includes a varied landscape of SaaS platforms, services, data integrations, and business processes. The role involves developing and sharing an architectural vision and roadmap for Shared Applications & Services, balancing long-term strategy with immediate needs. Working closely with teams in Sales, Marketing, Finance, and Operations, the Business Systems Architect makes practical decisions that align business goals with technical delivery. The position requires designing and guiding cross-system solutions, relying on experience, sound judgment, and facilitation skills rather than authority. Establishing architectural standards and shaping group decision-making processes are also key parts of this role. Location This position is based in Cambridge.

Join GT Biosciences, a pioneering techbio startup based in Cambridge, MA, dedicated to revolutionizing drug delivery through our innovative Deliveromics platform. We are seeking a passionate and multidisciplinary LNP Scientist to join our team, focusing on the advancement of cutting-edge non-viral delivery technologies.In this pivotal role, you will spearhead the design and development of novel ionizable lipids and engineer ligand-conjugated lipid nanoparticle formulations. Your expertise will support in vivo screening for Deliveromics and evaluate performance through both in vitro assays and in vivo animal models. You will be responsible for experimental planning, execution, data analysis, interpretation, and effectively communicating results.As one of the earliest scientific hires at this innovative startup, you will play a crucial role in shaping platform development and collaborating across various disciplines to create transformative solutions for genetic medicine delivery. This is a full-time, in-person position based in Cambridge, MA.

Nuvalent, Inc. is seeking a Senior Director of Clinical Pharmacology to lead our clinical pharmacology team. This pivotal role involves developing and executing clinical pharmacology strategies to support our innovative drug candidates. The ideal candidate will have extensive experience in clinical pharmacology and a passion for advancing novel therapies.

About Us:GT Biosciences is an innovative techbio startup focused on revolutionizing drug delivery through our groundbreaking platform, Deliveromics. This AI-powered, high-throughput, multiplexed in vivo data engine is designed to uncover the fundamental rules of drug delivery. Founded by a team of MIT PhDs and an esteemed MIT professor, and supported by leading investors, we are dedicated to developing next-generation, non-viral, cell-type-specific delivery systems. Our passionate, science-driven team is on a mission to make routine in vivo cell reprogramming a reality.We embrace a culture of transparency and collaboration, seeking enthusiastic team members who thrive in an open, cooperative environment and aspire to grow alongside the company and their colleagues.Job Overview:We are looking for a dedicated and multidisciplinary Nucleic Acids Platform Scientist to join our Deliveromics Platform Development team. In this pivotal role, you will design and optimize innovative nucleic acid constructs and chemistries, including mRNA, ASO, and siRNA, for targeted delivery applications. Your responsibilities will include supporting Deliveromics in vivo screening and conducting thorough evaluations of performance through both in vitro assays and animal models. You will independently plan and execute experiments, analyze complex datasets, and communicate findings effectively. As an early scientific hire at our emerging biotech firm, you will play a crucial role in shaping our platform, fostering interdisciplinary collaboration, and contributing to transformative delivery solutions for genetic medicines. This is a full-time, on-site position located in Cambridge, MA.

Amylyx Pharmaceuticals is on a bold mission to revolutionize the treatment of diseases with significant unmet needs. Where others see obstacles, we identify opportunities, approaching them with urgency, rigorous scientific inquiry, and an unwavering dedication to the communities we serve. As a clinical-stage organization, we are currently focused on conditions such as post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).Our commitment is fueled by our dynamic team. Our core values—be audacious, be curious, be authentic, be engaged, and be accountable—foster a culture of compassion and action. We have assembled a knowledgeable team poised to make an impact because the communities we support cannot afford delays. If you share our enthusiasm and are driven to tackle some of medicine’s most challenging issues, we invite you to explore this opportunity and apply.The Vice President of Clinical Pharmacology will lead and support the clinical pharmacology team, overseeing the strategic direction for evaluating the pharmacokinetic (PK), pharmacodynamic (PD), and immunogenicity characteristics of all drug candidates in development, extending through commercialization when applicable. As the clinical pharmacology authority within the organization, you will leverage your matrixed leadership and team development skills to guide, mentor, and educate cross-functional teams. Additionally, you will have the chance to engage in diligence assessments. Reporting directly to the Senior Vice President and Head of Clinical Development, you will maintain a high profile within the leadership team, including interactions with the Chief Medical Officer. Your ability to synthesize both internal and external data will be crucial in formulating the clinical pharmacology strategy.