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Essential Functions:Provide technical support during manufacturing processes. Collaborate effectively with CDMO partners. Contribute to process development and validation activities. Maintain laboratory presence and execute experiments independently. Analyze data and communicate findings through technical documentation. Interface with cross-functional teams and external partners.
About the job
Join Our Mission to Safeguard Humanity!
Vaxcyte is a pioneering clinical-stage vaccine development company dedicated to engineering high-fidelity vaccines aimed at protecting humanity from the severe and expensive health repercussions of bacterial diseases. Our mission extends to eradicating or effectively treating bacterial infections, including invasive pneumococcal disease, Group A Strep, and Shigella. With a clear and strategic path to success, Vaxcyte is poised for significant achievements in this critical field.
Our Approach Matters! We are driven by four fundamental core values:
*RETHINK CONVENTION: We embrace creativity and intellectual diversity across all aspects of our work to innovate and continuously improve vaccine delivery methods.
*AIM HIGH: We are committed to achieving our bold goal of developing the most complex biologics ever created for the protection of humanity.
*LEAD WITH HEART: At Vaxcyte, we prioritize a kindness-first, inclusive approach to collaboration and rigorous debate to further our business objectives.
*MODEL EXCELLENCE: The challenges we face demand our collective commitment to integrity, accountability, equality, and clarity in communications and decision-making.
Position Overview:
The Development organization consists of four Process teams: Protein, Polysaccharide, Conjugate Drug Substance (Conjugation), and Drug Product, all supported by Analytical and Formulation Development teams. Vaxcyte is looking for an Associate Engineer II with a solid foundation in vaccine or biologics process development and manufacturing to join our Polysaccharide Clinical Manufacturing/Process Development team.
The successful candidate will provide essential technical support for manufacturing activities in collaboration with our CDMO partners, while actively contributing to process development and validation efforts. This role demands a significant laboratory presence (over 50%) and the capacity to independently execute and document experiments, analyze data, and convey results through technical reports and presentations. The ideal candidate will work collaboratively across departments and may also engage with external CDMO partners to facilitate manufacturing campaigns and process transfers.
About Vaxcyte
Vaxcyte is a leader in vaccine innovation, committed to advancing health through the development of high-fidelity vaccines targeting bacterial diseases. Our team is passionate about creating solutions that aim to protect humankind and transform public health.
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Search for Supplier Development Engineer Structural Die Casting
Full-time|$133K/yr - $195K/yr|On-site|San Carlos, California, United States
About 1X 1X develops humanoid robots designed to work alongside people, helping address labor shortages and support economic growth. Role Overview The Supplier Development Engineer - Structural Die Casting will strengthen 1X’s supply chain by ensuring suppliers deliver high-quality precision structural components for advanced bipedal humanoids. This role is based on-site in San Carlos, CA. The engineer will play a key part in both launching new products and supporting ongoing production. What You Will Do Work with engineering and sourcing teams to identify and select suppliers skilled in die casting, machining, and structural assembly. Source and assess vendors for castings, extrusions, machined parts, and sheet metal components. Validate supplier processes for surface treatments, welding, heat treatments, and coatings. Review GD&T on complex structural parts and verify accuracy with metrology tools. Support lightweighting and design optimization projects. Oversee supplier industrialization from early design through production ramp-up. Help suppliers qualify tooling, equipment, and processes. Assess supplier readiness for vehicle production and manage related risks. Facilitate APQP and support PPAP at production launch. Educate suppliers on 1X’s quality management systems and review part quality documentation. Lead root cause analysis and corrective actions for supplier quality issues. Track and report supplier quality metrics, driving ongoing improvement. Apply lean and quality tools to improve supply chain performance. Travel up to 40% domestically and internationally, often with short notice.
Full-time|$133K/yr - $195K/yr|On-site|San Carlos, California, United States
Supplier Development Engineer, Motors & Magnets | Supply ChainLocation: San Carlos, CA (on-site)About 1XAt 1X, we are revolutionizing the future of work by developing humanoid robots designed to assist humans in overcoming labor shortages and driving efficiency.Role OverviewAs a Supplier Development Engineer focusing on Motors and Magnetic Systems, you will play a pivotal role in ensuring supplier readiness and product quality for the components that power our cutting-edge humanoid robots. Your responsibilities will involve cross-functional collaboration to guarantee that all critical components meet our stringent standards for performance, reliability, and scalability.ResponsibilitiesCollaborate with engineering and sourcing teams to identify and select suppliers based on their capabilities in motor and magnetic component manufacturing.Conduct thorough evaluations of suppliers’ motor winding, rotor/stator assembly, and magnet bonding processes.Ensure suppliers maintain consistency in torque-speed characteristics, thermal performance, and EMI compliance.Assist with rotor balancing, bearing preload setups, and encoder integration.Lead the supplier industrialization process from design through production ramp-up.Support suppliers in tooling, equipment, and process qualifications.Evaluate supplier readiness for vehicle builds and manage production risk effectively.Drive the Advanced Product Quality Planning (APQP) process and support Production Part Approval Process (PPAP) leading up to production initiation.Train suppliers on 1X’s quality systems and review quality documentation for parts.Lead root cause analysis and corrective action initiatives for supplier quality challenges.Monitor and report on supplier quality metrics to ensure ongoing improvement.Utilize lean and quality tools to foster continuous improvement across the supply chain.Willingness to travel up to 40%, domestically and internationally, sometimes on short notice.
Full-time|$142K/yr - $165K/yr|On-site|San Carlos, California, United States
Vaxcyte, Inc. seeks a Manager of Quality Management System (QMS) Vendor Management & Supplier Notifications to lead supplier-related quality activities. Based in San Carlos, California, this position plays a key role in maintaining and improving supplier compliance within Vaxcyte’s QMS, with a focus on timely and accurate handling of supplier notifications. Role overview This manager oversees the intake, triage, and coordination of supplier notifications using Veeva QMS. The role requires close collaboration across departments to evaluate risks, support change controls, and ensure that supplier compliance standards are met. Responsibilities also include participating in vendor qualification, supplier management, and assisting with audits when needed. Main responsibilities Supplier notification management: Manage the full process for supplier notifications in Veeva QMS, from intake and triage to prioritization and tracking. Conduct initial reviews of supplier notifications to determine necessary actions and assess potential impacts. Coordinate with cross-functional teams to ensure thorough impact assessments and follow-up steps are completed. Collaboration and compliance This position works with teams across the company to evaluate supplier-related risks and support ongoing supplier management. The manager may also contribute to internal and external audits as required.
Full-time|$145K/yr - $222K/yr|On-site|San Carlos, California, United States
Global Supply Manager, Structures | Supply ChainLocation: San Carlos, CA (on-site)About 1XAt 1X, we are at the forefront of innovation, building humanoid robots that collaborate with humans to address labor shortages and foster a future of abundance.Role OverviewWe are in search of a dedicated Global Supply Manager to lead the global sourcing of structural components such as frames, enclosures, and pivotal structural systems. Your contributions will be crucial in establishing a robust and scalable supply chain that ensures the reliable production of our next-generation humanoid robots.Key ResponsibilitiesFormulate and implement sourcing strategies for structural components, encompassing metals, plastics, and composites.Identify, assess, and onboard global suppliers that fulfill our stringent quality, cost, and delivery criteria.Negotiate contracts, pricing, and delivery terms to secure advantageous agreements.Collaborate with engineering teams to ensure parts meet both mechanical and aesthetic specifications.Support initiatives aimed at cost optimization while maintaining durability and consistency.Conduct supplier benchmarking and stay abreast of technology and pricing trends.Monitor supplier performance metrics to ensure adherence to contractual obligations.Implement risk mitigation strategies, including alternate sourcing and diversification.Provide technical support for Design for Manufacturing (DFM) efforts with an emphasis on structural systems.Manage supplier audits and drive continuous improvements where necessary.Work collaboratively with manufacturing, operations, and quality teams to ensure seamless integration.
Full-time|$165K/yr - $193K/yr|On-site|San Carlos, California, United States
Join Our Mission to Safeguard Humanity!Vaxcyte is a pioneering clinical-stage vaccine innovation company dedicated to engineering high-fidelity vaccines aimed at protecting humankind from the dire consequences of bacterial diseases, which can lead to severe and costly health issues if not addressed. Our efforts to combat and potentially eliminate bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella are just the beginning of our journey towards success. Vaxcyte is strategically positioned to achieve its goals. Our Work Philosophy: We believe that what we do is as crucial as how we go about it! Our collaborative efforts are guided by four foundational core values: *RETHINK CONVENTION: We embrace intellectual diversity and creativity at every level to innovate and continuously improve vaccine delivery methods. *AIM HIGH: We strive to achieve our ambitious goal of creating the most complex biologics ever developed to protect humanity. *LEAD WITH HEART: Every team member at Vaxcyte approaches leadership with kindness and inclusivity, fostering collaboration and constructive debate to meet our business objectives. *MODEL EXCELLENCE: The scale of our mission demands a unified commitment to integrity, accountability, equality, and clear communication in all our decisions. Position Overview:Vaxcyte is seeking an enthusiastic and skilled Senior Engineer to join our Polysaccharide Development and Manufacturing team within the CMC group. The successful candidate will play a pivotal role in developing a multi-valent polysaccharide-based conjugate vaccine, utilizing a novel carrier protein produced via the Xpress CF platform. With a strong emphasis on downstream purification for early-stage development and late-stage process characterization, the ideal candidate should possess significant experience in these areas. Familiarity with Design of Experiments (DOE) methodologies and proficiency in statistical software (e.g., JMP) are essential. Proven leadership in project initiatives and team management is required. The candidate must be eager to acquire new lab skills, as they will collaborate on experimental designs and execute experiments to advance our polysaccharide development and manufacturing initiatives. This role entails over 50% laboratory time, and the candidate should be capable of working independently and in collaboration with cross-functional teams.
Contract|On-site|San Carlos, California, United States
Be Part of Our Life-Saving Mission!At Vaxcyte, we are at the forefront of vaccine innovation, dedicated to creating high-fidelity vaccines designed to safeguard humankind from the severe health implications of bacterial diseases. Our commitment to combating bacterial infections, including invasive pneumococcal disease, Group A Strep, and Shigella, is just the beginning. We have a clear and robust roadmap for our success, and we are poised to make a significant impact.Our Approach: The impact of our work is matched only by the values that guide us:*RETHINK CONVENTION: We embrace creativity and intellectual diversity in every aspect of our work to revolutionize vaccine delivery.*AIM HIGH: We strive courageously toward our ambitious goal of developing the most complex biologics in history for humanity's protection.*LEAD WITH HEART: At Vaxcyte, every individual is a leader, fostering an inclusive and kind environment where collaboration and constructive debate drive our business objectives forward.*MODEL EXCELLENCE: Our challenges require a shared commitment to integrity, accountability, equality, and clarity in all communications and decision-making processes.Position Overview:We are looking for a dedicated Engineer I to join our Upstream Process Development team within the Protein Development and CMC group. This role offers an exciting opportunity to work alongside a highly skilled team focused on bacterial fermentation development.The ideal candidate will possess the following skills and attributes:Hands-on experience in operating and maintaining bioreactors, including Ambr® 250, at laboratory scale.Familiarity with pilot-scale fermentation and recovery equipment is advantageous.Proficiency in data analysis and presentation for process enhancement, troubleshooting, and optimization.A true team player who collaborates effectively, communicates openly, and is committed to achieving optimal outcomes aligned with company objectives.Exceptional organizational and planning skills.
About Beacon AIAt Beacon AI, we are a dynamic team of aviators, engineers, and operators committed to developing an AI platform that enhances the safety, efficiency, and capabilities of aviation. With the backing of top investors, we have secured numerous Department of Defense contracts and formed partnerships with leading airlines to deliver critical systems. Our culture promotes agility and collaboration, allowing small, focused teams to take ownership of their projects, deliver quickly, and innovate at the intersection of human and AI collaboration in aviation.Role OverviewWe are in search of a Frontend Web Application Engineer to join our innovative team and contribute to the development of impactful web interfaces for our flight safety platform. This role involves close collaboration with senior engineers, product managers, and designers to create user-centric features that facilitate the interaction with complex aviation data. You will enhance existing production systems, develop your technical expertise, and play a crucial role in advancing flight safety and operational efficiency.
Full-time|On-site|San Carlos, California, United States
Role OverviewWe are on the lookout for an innovative RF Engineer to lead the design, development, and enhancement of the head sub-system for our advanced humanoid robot, NEO. In this role, you will be instrumental in creating and integrating RF systems that facilitate the robot's expressive, perceptive, and operational capabilities.Your responsibilities will include hands-on design, prototyping, and system integration, collaborating closely with mechanical, software, manufacturing, and industrial design teams. You will oversee connectivity components and assemblies throughout their lifecycle, from initial concept and prototyping to validation and mass production. Your contributions will significantly impact the reliability, safety, aesthetics, and scalability of humanoid robots deployed globally.The ideal candidate is a creative problem-solver with a strong background in RF design, thriving in a dynamic product development environment.
Director of Software and Firmware DevelopmentAbout AetherfluxAt Aetherflux, we are pioneering the infrastructure that will drive and interconnect the orbital economy. Our innovative, modular satellites harness solar energy in Low Earth Orbit, providing a range of integrated applications including energy transmission via infrared lasers (both space-to-earth and space-to-space), powering on-orbit high-performance computing clusters (GPU/TPU), and delivering secure, high-bandwidth optical data transport.Today’s energy and data systems depend on intricate logistics and antiquated infrastructure. Aetherflux addresses these challenges by facilitating direct, on-demand, secure, and scalable energy distribution and data processing from space. This transformative approach will revolutionize operations both in orbit and on Earth, supporting the rapidly growing space industrial base, In-Space Servicing, Assembly, and Manufacturing (ISAM) operations, remote areas, and mission-critical environments.Founded in 2024 by Baiju Bhatt, inspired by his father's contributions at NASA Langley Research Center, Baiju holds a B.S. in Physics and an M.S. in Mathematics from Stanford University. He also co-founded Robinhood, which has empowered over 20 million Americans to access the financial system, and is now a publicly traded company.Aetherflux has successfully raised $90 million from leading investors including Index Ventures, Interlagos, Construct Ventures, Breakthrough Energy Ventures, Andreessen Horowitz, NEA, and others.This mission is ambitious and requires exceptional talent. Our team comprises experts from organizations like SpaceX, Astranis, NASA, Anduril, and the U.S. Navy, and is located in San Carlos, CA. If you are eager to tackle complex technical challenges and contribute to the creation of a generational energy and infrastructure company, we encourage you to apply.The RoleWe are in search of a Head of Software and Firmware to spearhead the architecture, development, and deployment of the comprehensive software stack that drives our space-based platforms. This includes everything from low-level firmware and embedded systems to onboard computing, autonomy, and distributed data processing.This leadership position encompasses the entire strategy related to firmware, embedded software, and higher-level onboard systems that facilitate energy transmission, real-time spacecraft control, and high-bandwidth data processing in orbit. You will define the co-design principles between software, firmware, and custom hardware, ensuring optimal performance in power-constrained, thermally dynamic, and radiation-exposed environments.You will collaborate cross-functionally with hardware, spacecraft, GNC, RF, and mission teams to deliver robust, high-performance, and fault-tolerant systems. This is a pivotal leadership role that carries significant accountability over system architecture and performance.
About Beacon AIAt Beacon AI, we are a dynamic team of aviators, engineers, and operators dedicated to developing an innovative AI platform aimed at enhancing the safety, efficiency, and capabilities of aviation. Supported by prominent investors, we proudly hold multiple Department of Defense contracts and collaborate with major airlines to implement critical systems. Our structure promotes agility and collaboration, allowing small, focused teams to take ownership of their projects, deliver swiftly, and continuously learn as they explore the integration of AI and human interaction in aviation.Role OverviewWe are on the lookout for a Lead Web Application Engineer who will provide technical leadership and strategic insights to our frontend team. In this pivotal role, you will spearhead the creation of impactful web interfaces that seamlessly connect with our flight safety platform, empowering users to engage with intricate aviation data and extract actionable insights. Your collaboration will span various disciplines, playing a crucial role in the advancement of aviation safety and operational capabilities.What You’ll DoDesign and implement features using React while architecting frontend systems to manage extensive, real-time, and historical aviation data.Integrate, process, and visualize data from diverse sources, encompassing live data streams and archived information.Guide and mentor engineers, promoting best practices through code reviews and architectural discussions.Collaborate with backend engineers, product managers, and UX/UI designers to make informed decisions regarding design and implementation.Guarantee the reliability and maintainability of frontend systems through automated testing, comprehensive documentation, and robust engineering standards.Develop reusable components and internal libraries to expedite future development.What Will Make You SuccessfulA minimum of 5 years of experience in building and delivering high-performance, user-centric web applications.Extensive knowledge of React, TypeScript, JavaScript, state management, and contemporary web standards (HTML/CSS).Strong proficiency in asynchronous frontend patterns and effectively managing live and historical data streams.Demonstrated ownership of complex features or product areas, from concept to delivery with high autonomy.A proactive and resourceful approach with the ability to operate effectively in a fast-paced environment.
About Beacon AIAt Beacon AI, we are a dynamic team of aviators, engineers, and operators dedicated to developing an innovative AI platform that enhances the safety, efficiency, and capability of flying. Supported by leading investors, we have secured multiple Department of Defense contracts and collaborated with major airlines to deliver essential systems. Our approach fosters collaboration without silos or cumbersome processes, enabling small, focused teams to take ownership of their projects, accelerate shipping, and rapidly learn as they redefine the interaction between humans and AI in aviation.Role OverviewWe are on the lookout for a talented iOS Software Engineer to join our mobile development team. In this role, you will contribute to the creation of impactful iOS applications that enhance our flight safety platform. Collaborating closely with senior engineers, designers, and product managers, you will develop user-facing features and support production systems. This position offers an excellent opportunity to deepen your iOS expertise while working on real-time, safety-critical applications that improve flight safety and enhance operational efficiency.
Full-time|$155K/yr - $250K/yr|On-site|San Carlos, California, United States
Join Our Team as an Embedded Linux Engineer – FoundationsLocation: San Carlos, CA (On-site)About the RoleAt 1X, we are revolutionizing the interaction between humans and robots through our innovative humanoid robot, NEO. NEO seamlessly integrates into homes, learns from visual stimuli, and collaborates with individuals. As an Embedded Linux Engineer, you will be pivotal in creating the Linux foundation that empowers this technology.This role is crucial as it serves as the bridge between hardware and intelligence, ensuring rapid boot times, system stability, effective debugging, and seamless updates. You will oversee the comprehensive development of our embedded Linux stack, from initial bring-up to deployment at scale, including Board Support Package (BSP), kernel, drivers, and distribution. The operating system is a core product, not an afterthought.Your Responsibilities:Design and maintain a customized embedded Linux distribution (using Yocto) tailored for 1X hardware, including BSP, root filesystem, and toolchain with reliable build and release processes.Lead the kernel and driver development processes: including device tree configuration, board bring-up, peripheral integration, performance optimization, and implementing a strategy for upstream/downstream Linux patches.Deliver high-quality system software that encompasses the boot chain, initialization processes, services, logging, crash management, and rapid deterministic startup.Develop tools for provisioning, flashing, and over-the-air updates across an expanding fleet, alongside automated testing and hardware bring-up procedures.Oversee platform management from prototype phases to high-volume production, making strategic decisions regarding reliability and optimization as hardware continues to evolve.Enhance CI/CD processes for embedded images, kernel builds, and validation procedures.Ideal Candidate Profile:Possess 5+ years of experience in deploying embedded Linux systems in production environments.Demonstrated experience in writing production-level device drivers for common buses (I2C, SPI, CAN, USB, Ethernet, PCIe) and the ability to interpret schematics to assess hardware behavior based on software indications.Experience with Yocto or Buildroot, showcasing a strong perspective on build systems, release engineering, and test automation.Proficiency in debugging at the kernel level, with the capability to trace software issues effectively.Comfortable taking ownership in dynamic environments where you set the standards.Compensation and Benefits:Competitive salary ranging from $155,000 to $250,000 + equity options.Comprehensive health, dental, and vision insurance.401(k) plan with company matching contributions.Generous paid time off and holiday benefits.Equal Opportunity Employer:1X is committed to fostering a diverse workplace. We encourage applications from all qualified candidates regardless of race, color, religion, sex, gender identity or expression, sexual orientation, national origin, ancestry, citizenship, age, marital status, medical condition, or any other characteristic protected by law.
Full-time|$163K/yr - $191K/yr|On-site|San Carlos, California, United States
Join Our Mission to Safeguard Humanity!Vaxcyte is a pioneering clinical-stage vaccine company dedicated to developing high-fidelity vaccines aimed at combating the far-reaching impacts of bacterial diseases. Our mission is not only to eradicate but also to treat serious bacterial infections, including invasive pneumococcal disease, Group A Strep, and Shigella. Our roadmap to success is clear and meticulously defined, positioning Vaxcyte to make significant strides in global health. At Vaxcyte, what we do is just as important as how we do it! Our collaborative efforts are driven by four core values: *RETHINK CONVENTION: We embrace creativity and intellectual diversity in every aspect of our work to innovate and continuously improve vaccine delivery methods. *AIM HIGH: We embody an audacious ambition to develop the most complex biologics ever attempted for the protection of humanity. *LEAD WITH HEART: At Vaxcyte, everyone leads with kindness and inclusivity, fostering collaboration and spirited debate to advance our business objectives. *MODEL EXCELLENCE: The magnitude of our challenges calls for a collective commitment to integrity, accountability, equality, and clear communication in all decisions.Position Overview:We are on the lookout for a highly skilled Senior Software Engineer with robust full-stack expertise and a strong DevOps inclination. This role is critical in designing, developing, testing, and maintaining scalable web applications that underpin essential business operations.The ideal candidate will demonstrate a solid combination of frontend and backend development skills and a disciplined approach to automation, testing, CI/CD, and production reliability. This position requires technical leadership, architectural foresight, and the capability to promote engineering excellence throughout the software lifecycle.Key Responsibilities:Full-Stack Application DevelopmentDesign, architect, and implement scalable applications using Next.js and React.Create and manage backend services and GraphQL APIs, focusing on schema design and performance enhancement.Maintain high standards of code quality, security, performance, and maintainability.Engage in architectural design reviews and participate in technical decision-making processes.
About Beacon AI Beacon AI brings together aviators, engineers, and operators to advance aviation through an AI-driven platform. The company’s mission centers on improving flight safety, efficiency, and capabilities. Backed by top investors, Beacon AI partners with the Department of Defense and major airlines to deliver essential systems. Teams work collaboratively, without silos, in small groups that own their projects from start to finish. This approach enables fast releases and ongoing learning as the team explores new ground in human and AI collaboration for aviation. Role Overview: iOS Software Engineer – Electronic Flight Bag (EFB) This hybrid role is based in San Carlos. The iOS Software Engineer joins the mobile team to build iOS applications, primarily for iPad, that power Beacon AI’s flight safety platform. The work centers on developing features that pilots and operators rely on, with a focus on usability and precision. What You Will Do Work alongside senior engineers and designers to deliver new features for iOS EFB applications Develop software that handles large aviation datasets, such as wind and weather data, with high performance Build and refine aviation instrument displays for accuracy and speed Integrate with external devices and enable advanced map navigation and location services Design for reliability in offline and low-connectivity environments, ensuring critical features remain available Contribute to robust, production-ready systems that support real-time, safety-critical operations What Matters for This Role Experience developing iOS applications, especially for iPad Background in Electronic Flight Bag (EFB) apps or similar aviation software Familiarity with handling large datasets and optimizing performance Knowledge of map navigation, location services, and device integration Understanding of designing apps for offline and low-connectivity use Commitment to building reliable and accurate tools for aviation professionals This position offers the chance to deepen iOS development skills while working on real-time, safety-critical applications in aviation.
Natera, Inc. is hiring a Scientist in Product Development to join the team in San Carlos, CA. This role centers on advancing genetic testing solutions and contributing to the company’s research and development efforts. Key responsibilities Design experiments that support the creation of new genetics products Analyze experimental results and interpret data to inform next steps Develop and refine methodologies to enhance Natera’s product offerings Collaborate with colleagues from different teams to drive research projects forward What makes this role unique This position provides a direct path to influence the future of genetics research and product development. Success depends on strong scientific knowledge and the ability to think critically about complex problems.
Contract|$62K/yr - $68K/yr|On-site|San Carlos, California, United States
Join Our Mission to Protect Humanity!At Vaxcyte, we are a pioneering clinical-stage vaccine innovation company dedicated to engineering high-fidelity vaccines aimed at safeguarding humanity from the dire consequences of bacterial diseases. Our goal is to combat serious bacterial infections, including invasive pneumococcal disease, Group A Strep, and Shigella. We are on a clear pathway to success, determined to make a significant impact in the world of vaccine development. Our Approach: We believe that what we do is as important as how we do it. Our collaborative work is anchored by four core values: *RETHINK CONVENTION: We embrace creative and intellectual diversity in all aspects of our work to innovate and transform vaccine delivery. *AIM HIGH: We strive to achieve audacious goals, courageously tackling the most complex biologics to protect humankind. *LEAD WITH HEART: At Vaxcyte, leadership is about kindness and inclusivity, fostering collaboration and robust discussions that further our mission. *MODEL EXCELLENCE: Our ambitious challenges necessitate a shared commitment to integrity, accountability, and clarity in our communications and decision-making processes.Position Overview:We invite a dynamic and skilled individual to become part of our Analytical Development team as a Scientist I. In this role, you will execute analytical testing and play a vital role in the development of analytical methods for our biologics and vaccine programs.This position entails performing both routine and advanced analytical assays utilizing modern techniques. You will support method optimization and troubleshooting, engage in continuous improvement initiatives with moderate supervision, and work effectively within cross-functional teams. The ideal candidate will possess hands-on laboratory experience, exceptional technical execution, and robust problem-solving abilities. You will independently plan and execute tasks, analyze and interpret data, and drive or escalate investigations as necessary. Additionally, you will author and maintain comprehensive technical documentation, including method protocols, development summaries, and SOPs, while effectively communicating experimental results to internal stakeholders.
Full-time|On-site|San Carlos, California, United States
Join Our Mission to Safeguard Humanity!Vaxcyte is a pioneering clinical-stage vaccine development company dedicated to engineering high-fidelity vaccines aimed at protecting humanity from the severe and expensive health repercussions of bacterial diseases. Our mission extends to eradicating or effectively treating bacterial infections, including invasive pneumococcal disease, Group A Strep, and Shigella. With a clear and strategic path to success, Vaxcyte is poised for significant achievements in this critical field. Our Approach Matters! We are driven by four fundamental core values: *RETHINK CONVENTION: We embrace creativity and intellectual diversity across all aspects of our work to innovate and continuously improve vaccine delivery methods. *AIM HIGH: We are committed to achieving our bold goal of developing the most complex biologics ever created for the protection of humanity. *LEAD WITH HEART: At Vaxcyte, we prioritize a kindness-first, inclusive approach to collaboration and rigorous debate to further our business objectives. *MODEL EXCELLENCE: The challenges we face demand our collective commitment to integrity, accountability, equality, and clarity in communications and decision-making.Position Overview:The Development organization consists of four Process teams: Protein, Polysaccharide, Conjugate Drug Substance (Conjugation), and Drug Product, all supported by Analytical and Formulation Development teams. Vaxcyte is looking for an Associate Engineer II with a solid foundation in vaccine or biologics process development and manufacturing to join our Polysaccharide Clinical Manufacturing/Process Development team.The successful candidate will provide essential technical support for manufacturing activities in collaboration with our CDMO partners, while actively contributing to process development and validation efforts. This role demands a significant laboratory presence (over 50%) and the capacity to independently execute and document experiments, analyze data, and convey results through technical reports and presentations. The ideal candidate will work collaboratively across departments and may also engage with external CDMO partners to facilitate manufacturing campaigns and process transfers.
Full-time|$213K/yr - $250K/yr|On-site|San Carlos, California, United States
Join Our Mission to Safeguard Humanity!Vaxcyte is a pioneering clinical-stage vaccine innovation enterprise dedicated to engineering high-fidelity vaccines aimed at protecting humanity from the dire consequences of bacterial diseases. Our efforts to eradicate or treat significant bacterial infections, including invasive pneumococcal disease, Group A Strep, and Shigella, are just the beginning. With a clear and well-defined path to success, Vaxcyte is poised to make a lasting impact. Our Approach is as crucial as Our Mission! We are guided by four core values that shape our collaborative efforts: *RETHINK CONVENTION: We embrace creative and intellectual diversity to innovate and continuously improve vaccine delivery methods. *AIM HIGH: Our audacious goal drives us to develop the most complex biologics ever devised to protect humankind. *LEAD WITH HEART: Collaboration and vigorous debate are fostered through a kindness-first, inclusive approach. *MODEL EXCELLENCE: Our challenge requires a shared commitment to integrity, accountability, equality, and clear communication in decision-making.Position Summary:Vaxcyte is looking for a distinguished Director of Immunoassay Development to spearhead and lead a dedicated analytical function focused on immunoassay development for intricate conjugated vaccines. This role will involve building and managing a laboratory team tasked with the development, maintenance, and continuous enhancement of potency- and antigenicity-based immunoassays to support CMC development from preclinical stages through BLA-stage programs and commercialization.A primary focus for this role will be the stewardship of the VAX-31 MSD immunoassay platform, which has advanced to Phase 3 due to extensive internal leadership in clinical serology, GLP studies, and immunoassay development. The ideal candidate will collaborate closely with the current immunoassay leadership to ensure effective knowledge transfer, maintain scientific and execution excellence, and ensure the long-term sustainability of the immunoassay strategy as accountability transitions into Analytical Development.This is a hands-on scientific leadership position embedded within CMC execution.
We are seeking a highly skilled Senior Scientist to join our Research and Development team at Natera in San Carlos, California. In this pivotal role, you will lead innovative projects that contribute to groundbreaking advancements in genetic testing and diagnostics. You will collaborate with cross-functional teams, driving research initiatives that enhance our product offerings and improve patient outcomes.
About Beacon AI Beacon AI builds advanced AI systems to improve aviation safety. The team partners with major airlines and holds Department of Defense contracts. With support from leading investors, Beacon AI focuses on integrating AI solutions that help humans and machines work together more effectively in flight operations. Role Overview: iOS Software Engineer - Health Wearable This hybrid role is based in San Carlos. The iOS Software Engineer will join the mobile team to develop applications for health and wearable technology. The work centers on building features for a flight safety platform, with a focus on health monitoring and data visualization for flight crews. What You Will Do Design and build iOS applications that support wearable health monitoring for aviation professionals Collaborate with senior engineers and designers to deliver user-focused features Create complex user interfaces that present biometric and health data in clear, actionable ways Help develop real-time wearable experiences that provide insights to improve crew safety and operational awareness Who We’re Looking For Experience developing iOS applications, especially for health or wearable devices Strong skills in building complex UIs and transforming large health data sets into user-friendly interfaces An eye for design and a user-first approach to feature development This position offers the chance to shape technology that supports aviation safety and crew wellbeing.
Apr 14, 2026
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